The role of the disulfide bond in the interaction of islet amyloid polypeptide with membranes

European Biophysics Journal

Volumn 39, Issue 9, 2010, Pages 1359-1364

  Khemtémourian, Lucie ^a   Engel, Maarten F M ^a,b,c   Kruijtzer, John A W ^a   Höppener, Jo W M ^b   Liskamp, Rob M J ^a   Killian, J Antoinette ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

2H NMR; Amylin; Circular dichroism; Model membranes; Protein membrane interactions; Type II diabetes mellitus

Indexed keywords

1-PALMITOYL-2-OLEOYLGLYCERO-3-PHOSPHOSERINE; 1-PALMITOYL-2-OLEOYLPHOSPHATIDYLCHOLINE; 2 OLEOYL 1 PALMITOYLPHOSPHATIDYLCHOLINE; 2 OLEOYL 1 PALMITOYLPHOSPHATIDYLSERINE; AMYLOID; DISULFIDE; PEPTIDE FRAGMENT; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLSERINE; PROTEIN BINDING;

AMINO ACID SEQUENCE; ARTICLE; CELL MEMBRANE; CHEMISTRY; CYTOLOGY; HUMAN; METABOLISM; MOLECULAR GENETICS; OXIDATION REDUCTION REACTION; PANCREAS ISLET; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE;

AMINO ACID SEQUENCE; AMYLOID; CELL MEMBRANE; DISULFIDES; HUMANS; ISLETS OF LANGERHANS; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; PEPTIDE FRAGMENTS; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLSERINES; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY;

EID: 77955654930     PISSN: 01757571     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00249-009-0572-4     Document Type: Article

References (31)

1. A Abedini SM Tracz JH Cho DP Raleigh 2006 Characterization of the heparin binding site in the N-terminus of human pro-islet amyloid polypeptide: implications for amyloid formation Biochemistry 45 9228 9237
2. B Akesson G Panagiotidis P Westermark I Lundquist 2003 Islet amyloid polypeptide inhibits glucagon release and exerts a dual action on insulin release from isolated islets Regul Pept 111 55 60
3. M Apostolidou SA Jayasinghe R Langen 2008 Structure of alpha-helical membrane-bound human islet amyloid polypeptide and its implications for membrane-mediated misfolding J Biol Chem 283 17205 17210
4. MS Balla JH Bowie F Separovic 2004 Solid-state NMR study of antimicrobial peptides from Australian frogs in phospholipid membranes Eur Biophys J 33 109 116
5. M Bloom JH Davis AL Mackay 1981 Direct determination of the oriented sample NMR spectrum from the powder spectrum for systems with a local axial symmetry Chem Phys Lett 80 198 202
6. JR Brender EL Lee MA Cavitt A Gafni DG Steel A Ramamoorthy 2008 Amyloid fiber formation and membrane disruption are separate processes localized in two distinct regions of IAPP, the type-2-diabetes-related peptide J Am Chem Soc 130 6424 6429
7. S Buchoux J Lai-Kee-Him M Garnier P Tsan F Besson A Brisson EJ Dufourc 2008 Surfactin-triggered small vesicle formation of negatively charged membranes: a novel membrane-lysis mechanism Biophys J 95 3840 3849
8. P Calvez S Bussieres D Eric C Salesse 2009 Parameters modulating the maximum insertion pressure of proteins and peptides in lipid monolayers Biochimie 91 718 733
9. RA Demel WS Geurts van Kessel RF Zwaal B Roelofsen LL van Deenen 1975 Relation between various phospholipase actions on human red cell membranes and the interfacial phospholipid pressure in monolayers Biochim Biophys Acta 406 97 107
10. A Demuro E Mina R Kayed SC Milton I Parker CG Glabe 2005 Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers J Biol Chem 280 17294 17300
11. MFM Engel 2009 Membrane permeabilization by islet amyloid polypeptide Chem Phys Lipids 160 1 10
12. MFM Engel H Yigittop RC Elgersma DT Rijkers RM Liskamp B de Kruijff JW Höppener JA Killian 2006 Islet amyloid polypeptide inserts into phospholipid monolayers as monomer J Mol Biol 356 783 789
13. MFM Engel L Khemtémourian CC Kleijer HJ Meeldijk J Jacobs AJ Verkleij B de Kruijff JA Killian JW Höppener 2008 Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane Proc Natl Acad Sci USA 105 6033 6038
14. JD Gehman CC O'Biren F Shabanpoor JD Wade F Separovic 2008 Metal effects on the membrane interactions of amyloid-β peptides Eur Biophys J 37 333 344
15. JW Höppener B Ahren CJ Lips 2000 Islet amyloid and type 2 diabetes mellitus N Engl J Med 343 411 419
16. J Janson RH Ashley D Harrison S McIntyre PC Butler 1999 The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles Diabetes 48 491 498
17. SA Jayasinghe R Langen 2007 Membrane interaction of islet amyloid polypeptide Biochim Biophys Acta 1768 2002 2009
18. R Kayed E Head JL Thompson TM McIntire SC Milton CW Cotman CG Glabe 2003 Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis Science 300 486 489
19. L Khemtémourian JA Killian JW Höppener MFM Engel 2008 Recent insights in islet amyloid polypeptide-induced membrane disruption and its role in beta-cell death in type 2 diabetes mellitus Exp Diabetes Res 2008 421287
20. JD Knight AD Miranker 2004 Phospholipid catalysis of diabetic amyloid assembly J Mol Biol 341 1175 1187
21. BW Koo AD Miranker 2005 Contribution of the intrinsic disulfide to the assembly mechanism of islet amyloid Prot Sci 14 231 239
22. TL Lau EE Ambroggio DJ Tew R Cappai CL Masters GD Fidelio KJ Barnham F Separovic 2006 Amyloid-β peptide disruption of lipid membranes and the effect of metal ions J Mol Biol 356 759 770
23. RP Nanga JR Brender J Xu K Hartman V Subramanian A Ramamoorthy 2009 Three-dimensional structure and orientation of rat islet amyloid polypeptide protein in a membrane environment by solution NMR spectroscopy J Am Chem Soc 131 8252 8261
24. TK Reda A Geliebter FX Pi-Sunyer 2002 Amylin, food intake, and obesity Obes Res 10 1087 1091
25. AN Roberts B Leighton JA Todd D Cockburn PN Schofield R Sutton S Holt Y Boyd AJ Day EA Foot AC Willis KBM Reid GJS Cooper 1989 Molecular and functional-characterization of amylin, a peptide associated with type-2 diabetes-mellitus Proc Natl Acad Sci USA 86 9662 9666
26. PA Rushing MM Hagan RJ Seeley TA Lutz DA D'Alessio EL Air SC Woods 2001 Inhibition of central amylin signaling increases food intake and body adiposity in rats Endocrinology 142 5035
27. I Rustenbeck A Matthies S Lenzen 1994 Lipid composition of glucose-stimulated pancreatic islets and insulin-secreting tumor cells Lipids 29 685 692
28. ES Salnikov AJ Mason B Bechinger 2009 Membrane order perturbation in the presence of antimicrobial peptides by (2)H solid-state NMR spectroscopy Biochimie 91 734 743
29. E Sparr MFM Engel DV Sakharov M Sprong J Jacobs B de Kruijff JWM Höppener JA Killian 2004 Islet amyloid polypeptide-induced membrane leakage involves uptake of lipids by forming amyloid fibers FEBS Lett 577 117 120
30. N Sreerama RW Woody 2000 Estimation of protein secondary structure from circular dichroism spectra: comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set Anal Biochem 287 252 260
31. P Westermark E Wilander GT Westermark KH Johnson 1987 Islet amyloid polypeptide-like immunoreactivity in the islet B cells of type 2 (non-insulin-dependent) diabetic and non-diabetic individuals Diabetologia 30 887 892