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Volumn 9, Issue , 2008, Pages

Association between variations in the TLR4 gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TOLL LIKE RECEPTOR 4; TLR4 PROTEIN, HUMAN; UNCLASSIFIED DRUG;

EID: 42049098225     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/1471-2350-9-9     Document Type: Article
Times cited : (31)

References (36)
  • 1
    • 21344460247 scopus 로고    scopus 로고
    • An immune origin of type 2 diabetes?
    • 10.1007/s00125-005-1764-9 15864529
    • Kolb H Mandrup-Poulsen T An immune origin of type 2 diabetes? Diabetologia 2005, 48:1038-1050. 10.1007/s00125-005-1764-9 15864529
    • (2005) Diabetologia , vol.48 , pp. 1038-1050
    • Kolb, H.1    Mandrup-Poulsen, T.2
  • 2
    • 33645312390 scopus 로고    scopus 로고
    • The epidemiology of low-grade chronic systemic inflammation and type 2 diabetes
    • 10.1089/dia.2006.8.7 16472046
    • Duncan BB Schmidt MI The epidemiology of low-grade chronic systemic inflammation and type 2 diabetes Diabetes Technol Ther 2006, 8:7-17. 10.1089/dia.2006.8.7 16472046
    • (2006) Diabetes Technol Ther , vol.8 , pp. 7-17
    • Duncan, B.B.1    Schmidt, M.I.2
  • 3
    • 0031720795 scopus 로고    scopus 로고
    • Is type II diabetes mellitus a disease of the innate immune system?
    • 10.1007/s001250051058 9794114
    • Pickup JC Crook MA Is type II diabetes mellitus a disease of the innate immune system? Diabetologia 1998, 41:1241-1248. 10.1007/s001250051058 9794114
    • (1998) Diabetologia , vol.41 , pp. 1241-1248
    • Pickup, J.C.1    Crook, M.A.2
  • 4
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • 10.1038/41131 9237759
    • Medzhitov R Preston-Hurlburt P Janeway CA Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity Nature 1997, 388:394-397. 10.1038/41131 9237759
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway Jr., C.A.3
  • 5
    • 0038242875 scopus 로고    scopus 로고
    • Toll-like receptor signaling pathways
    • 10.1126/science.1085536 12791976
    • Barton GM Medzhitov R Toll-like receptor signaling pathways Science 2003, 300:1524-1525. 10.1126/science.1085536 12791976
    • (2003) Science , vol.300 , pp. 1524-1525
    • Barton, G.M.1    Medzhitov, R.2
  • 7
    • 0034650427 scopus 로고    scopus 로고
    • Cutting edge: Heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex
    • 10623794
    • Ohashi K Burkart V Flohe S Kolb H Cutting edge: Heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex J Immunol 2000, 164:558-561. 10623794
    • (2000) J Immunol , vol.164 , pp. 558-561
    • Ohashi, K.1    Burkart, V.2    Flohe, S.3    Kolb, H.4
  • 8
    • 0035451118 scopus 로고    scopus 로고
    • Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4
    • 11509636
    • Smiley ST King JA Hancock WW Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4 J Immunol 2001, 167:2887-2894. 11509636
    • (2001) J Immunol , vol.167 , pp. 2887-2894
    • Smiley, S.T.1    King, J.A.2    Hancock, W.W.3
  • 9
    • 0037449723 scopus 로고    scopus 로고
    • Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells
    • 10.1074/jbc.M209634200 12424240
    • Miller YI Viriyakosol S Binder CJ Feramisco JR Kirkland TN Witztum JL Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells J Biol Chem 2003, 278:1561-1568. 10.1074/jbc.M209634200 12424240
    • (2003) J Biol Chem , vol.278 , pp. 1561-1568
    • Miller, Y.I.1    Viriyakosol, S.2    Binder, C.J.3    Feramisco, J.R.4    Kirkland, T.N.5    Witztum, J.L.6
  • 11
    • 33750584214 scopus 로고    scopus 로고
    • TLR4 links innate immunity and fatty acid-induced insulin resistance
    • 1616196 17053832 10.1172/JCI28898
    • Shi H Kokoeva MV Inouye K Tzameli I Yin H Flier JS TLR4 links innate immunity and fatty acid-induced insulin resistance J Clin Invest 2006, 116:3015-3025. 1616196 17053832 10.1172/JCI28898
    • (2006) J Clin Invest , vol.116 , pp. 3015-3025
    • Shi, H.1    Kokoeva, M.V.2    Inouye, K.3    Tzameli, I.4    Yin, H.5    Flier, J.S.6
  • 12
    • 0035093810 scopus 로고    scopus 로고
    • Diabetes mellitus: A hypercoagulable state
    • 10.1016/S1056-8727(00)00132-X 11259926
    • Carr ME Diabetes mellitus: A hypercoagulable state J Diabetes Complications 2001, 15:44-54. 10.1016/S1056-8727(00)00132-X 11259926
    • (2001) J Diabetes Complications , vol.15 , pp. 44-54
    • Carr, M.E.1
  • 13
    • 19244377379 scopus 로고    scopus 로고
    • Effect of hyperglycemia and hyperlipidemia on atherosclerosis in LDL receptor-deficient mice: Establishment of a combined model and association with heat shock protein 65 immunity
    • 10.2337/diabetes.49.6.1064
    • Keren P George J Shaish A Levkovitz H Janakovic Z Afek A Goldberg I Kopolovic J Keren G Harats D Effect of hyperglycemia and hyperlipidemia on atherosclerosis in LDL receptor-deficient mice: Establishment of a combined model and association with heat shock protein 65 immunity Diabetes 2000, 49:1064-1069. 10.2337/diabetes.49.6.1064 10866061
    • (2000) Diabetes , vol.49 , pp. 1064-1069
    • Keren, P.1    George, J.2    Shaish, A.3    Levkovitz, H.4    Janakovic, Z.5    Afek, A.6    Goldberg, I.7    Kopolovic, J.8    Keren, G.9    Harats, D.10
  • 14
    • 0038639229 scopus 로고    scopus 로고
    • Associations between inflammatory markers, traditional risk factors, and complications in patients with type 2 diabetes mellitus
    • 10.1016/S1056-8727(02)00204-0 12738395
    • Streja D Cressey P Rabkin SW Associations between inflammatory markers, traditional risk factors, and complications in patients with type 2 diabetes mellitus J Diabetes Complications 2003, 17:120-127. 10.1016/ S1056-8727(02)00204-0 12738395
    • (2003) J Diabetes Complications , vol.17 , pp. 120-127
    • Streja, D.1    Cressey, P.2    Rabkin, S.W.3
  • 15
    • 0035104119 scopus 로고    scopus 로고
    • LPS induction of gene expression in human monocytes
    • 10.1016/S0898-6568(00)00149-2 11257452
    • Guha M Mackman N LPS induction of gene expression in human monocytes Cell Signal 2001, 13:85-94. 10.1016/S0898-6568(00)00149-2 11257452
    • (2001) Cell Signal , vol.13 , pp. 85-94
    • Guha, M.1    Mackman, N.2
  • 16
    • 0030615201 scopus 로고    scopus 로고
    • Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases
    • 10.1056/NEJM199704103361506 9091804
    • Barnes PJ Karin M Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases N Engl J Med 1997, 336:1066-1071. 10.1056/NEJM199704103361506 9091804
    • (1997) N Engl J Med , vol.336 , pp. 1066-1071
    • Barnes, P.J.1    Karin, M.2
  • 19
    • 25844489169 scopus 로고    scopus 로고
    • Elevated levels of interleukin-18 predict the development of type 2 diabetes: Results from the MONICA/KORA Augsburg Study, 1984-2002
    • 10.2337/diabetes.54.10.2932 16186395
    • Thorand B Kolb H Baumert J Koenig W Chambless L Meisinger C Illig T Martin S Herder C Elevated levels of interleukin-18 predict the development of type 2 diabetes: Results from the MONICA/KORA Augsburg Study, 1984-2002 Diabetes 2005, 54:2932-2938. 10.2337/ diabetes.54.10.2932 16186395
    • (2005) Diabetes , vol.54 , pp. 2932-2938
    • Thorand, B.1    Kolb, H.2    Baumert, J.3    Koenig, W.4    Chambless, L.5    Meisinger, C.6    Illig, T.7    Martin, S.8    Herder, C.9
  • 20
    • 23844467739 scopus 로고    scopus 로고
    • KORA - A research platform for population based health research
    • 16032513
    • Holle R Happich M Lowel H Wichmann HE KORA - a research platform for population based health research Gesundheitswesen 2005, 67 Suppl 1:S19-S25. 16032513
    • (2005) Gesundheitswesen , vol.67 , Issue.SUPPL. 1
    • Holle, R.1    Happich, M.2    Lowel, H.3    Wichmann, H.E.4
  • 23
    • 0037074191 scopus 로고    scopus 로고
    • Sex differences in risk factors for incident type 2 diabetes mellitus: The MONICA Augsburg cohort study
    • 10.1001/archinte.162.1.82 11784224
    • Meisinger C Thorand B Schneider A Stieber J Doring A Lowel H Sex differences in risk factors for incident type 2 diabetes mellitus: The MONICA Augsburg cohort study Arch Intern Med 2002, 162:82-89. 10.1001/ archinte.162.1.82 11784224
    • (2002) Arch Intern Med , vol.162 , pp. 82-89
    • Meisinger, C.1    Thorand, B.2    Schneider, A.3    Stieber, J.4    Doring, A.5    Lowel, H.6
  • 24
    • 0028610431 scopus 로고
    • Robust variance estimation for the case-cohort design
    • 10.2307/2533444 7786988
    • Barlow WE Robust variance estimation for the case-cohort design Biometrics 1994, 50:1064-1072. 10.2307/2533444 7786988
    • (1994) Biometrics , vol.50 , pp. 1064-1072
    • Barlow, W.E.1
  • 25
    • 34147109919 scopus 로고    scopus 로고
    • Sex Differences in the Prediction of Type 2 Diabetes by Inflammatory Markers: Results from the MONICA/KORA Augsburg case-cohort study, 1984-2002
    • 10.2337/dc06-1693 17392546
    • Thorand B Baumert J Kolb H Meisinger C Chambless L Koenig W Herder C Sex Differences in the Prediction of Type 2 Diabetes by Inflammatory Markers: Results from the MONICA/KORA Augsburg case-cohort study, 1984-2002 Diabetes Care 2007, 30:854-860. 10.2337/dc06-1693 17392546
    • (2007) Diabetes Care , vol.30 , pp. 854-860
    • Thorand, B.1    Baumert, J.2    Kolb, H.3    Meisinger, C.4    Chambless, L.5    Koenig, W.6    Herder, C.7
  • 26
    • 0036155283 scopus 로고    scopus 로고
    • Score tests for association between traits and haplotypes when linkage phase is ambiguous
    • 384917 11791212 10.1086/338688
    • Schaid DJ Rowland CM Tines DE Jacobson RM Poland GA Score tests for association between traits and haplotypes when linkage phase is ambiguous Am J Hum Genet 2002, 70:425-434. 384917 11791212 10.1086/338688
    • (2002) Am J Hum Genet , vol.70 , pp. 425-434
    • Schaid, D.J.1    Rowland, C.M.2    Tines, D.E.3    Jacobson, R.M.4    Poland, G.A.5
  • 27
    • 30744434862 scopus 로고    scopus 로고
    • Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix
    • 10.1038/sj.hdy.6800717 16077740
    • Li J Ji L Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix Heredity 2005, 95:221-227. 10.1038/ sj.hdy.6800717 16077740
    • (2005) Heredity , vol.95 , pp. 221-227
    • Li, J.1    Ji, L.2
  • 29
    • 10744226206 scopus 로고    scopus 로고
    • The endotoxin receptor TLR4 polymorphism is not associated with diabetes or components of the metabolic syndrome
    • 10.2337/diabetes.52.11.2861 14578307
    • Illig T Bongardt F Schopfer A Holle R Muller S Rathmann W Koenig W Meisinger C Wichmann HE Kolb H The endotoxin receptor TLR4 polymorphism is not associated with diabetes or components of the metabolic syndrome Diabetes 2003, 52:2861-2864. 10.2337/diabetes.52.11.2861 14578307
    • (2003) Diabetes , vol.52 , pp. 2861-2864
    • Illig, T.1    Bongardt, F.2    Schopfer, A.3    Holle, R.4    Muller, S.5    Rathmann, W.6    Koenig, W.7    Meisinger, C.8    Wichmann, H.E.9    Kolb, H.10
  • 30
    • 10644236977 scopus 로고    scopus 로고
    • Toll-like receptor 4 gene Asp299Gly polymorphism is associated with reductions in vascular inflammation, angiographic coronary artery disease, and clinical diabetes
    • 10.1016/j.ahj.2004.05.049 15632890
    • Kolek MJ Carlquist JF Muhlestein JB Whiting BM Horne BD Bair TL Anderson JL Toll-like receptor 4 gene Asp299Gly polymorphism is associated with reductions in vascular inflammation, angiographic coronary artery disease, and clinical diabetes Am Heart J 2004, 148:1034-1040. 10.1016/ j.ahj.2004.05.049 15632890
    • (2004) Am Heart J , vol.148 , pp. 1034-1040
    • Kolek, M.J.1    Carlquist, J.F.2    Muhlestein, J.B.3    Whiting, B.M.4    Horne, B.D.5    Bair, T.L.6    Anderson, J.L.7
  • 32
    • 33745251699 scopus 로고    scopus 로고
    • Dysregulated Toll-like receptor expression and signaling in bone marrow-derived macrophages at the onset of diabetes in the non-obese diabetic mouse
    • 10.1093/intimm/dxl045 16728431
    • Mohammad MK Morran M Slotterbeck B Leaman DW Sun Y Grafenstein H Hong SC McInerney MF Dysregulated Toll-like receptor expression and signaling in bone marrow-derived macrophages at the onset of diabetes in the non-obese diabetic mouse Int Immunol 2006, 18:1101-1113. 10.1093/intimm/ dxl045 16728431
    • (2006) Int Immunol , vol.18 , pp. 1101-1113
    • Mohammad, M.K.1    Morran, M.2    Slotterbeck, B.3    Leaman, D.W.4    Sun, Y.5    Grafenstein, H.6    Hong, S.C.7    McInerney, M.F.8
  • 33
    • 33745187112 scopus 로고    scopus 로고
    • Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytes
    • 10.1016/j.bbrc.2006.05.170 16781673
    • Song MJ Kim KH Yoon JM Kim JB Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytes Biochem Biophys Res Commun 2006, 346:739-745. 10.1016/j.bbrc.2006.05.170 16781673
    • (2006) Biochem Biophys Res Commun , vol.346 , pp. 739-745
    • Song, M.J.1    Kim, K.H.2    Yoon, J.M.3    Kim, J.B.4
  • 35
    • 0242361567 scopus 로고    scopus 로고
    • Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism
    • 10.1016/S1097-2765(03)00384-8 14580333
    • Castrillo A Joseph SB Vaidya SA Haberland M Fogelman AM Cheng G Tontonoz P Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism Mol Cell 2003, 12:805-816. 10.1016/S1097-2765(03)00384-8 14580333
    • (2003) Mol Cell , vol.12 , pp. 805-816
    • Castrillo, A.1    Joseph, S.B.2    Vaidya, S.A.3    Haberland, M.4    Fogelman, A.M.5    Cheng, G.6    Tontonoz, P.7


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