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Volumn 29, Issue 5, 2010, Pages 359-372

Pathogenic mechanisms of congenital heart disease

Author keywords

Cardiac development; Congenital heart disease; Molecular mechanisms

Indexed keywords

CONGENITAL HEART DISEASE; GENETIC DISORDER; HEART DEVELOPMENT; HUMAN; MOLECULAR GENETICS; PATHOGENESIS; PRIORITY JOURNAL; REVIEW;

EID: 77955646966     PISSN: 15513815     EISSN: 15513823     Source Type: Journal    
DOI: 10.3109/15513811003789628     Document Type: Review
Times cited : (12)

References (68)
  • 1
    • 0037134945 scopus 로고    scopus 로고
    • The incidence of congenital heart disease
    • Hoffman JI, Kaplan S. The incidence of congenital heart disease. J Am Coll Cardiol 39:1890-1900, 2002.
    • (2002) J Am Coll Cardiol , vol.39 , pp. 1890-1900
    • Hoffman, J.I.1    Kaplan, S.2
  • 2
    • 33745320481 scopus 로고    scopus 로고
    • Insights into the genetic basis of congenital heart disease
    • Garg V. Insights into the genetic basis of congenital heart disease. Cell Mol Life Sci 63(10):1141-1148, 2006.
    • (2006) Cell Mol Life Sci , vol.63 , Issue.10 , pp. 1141-1148
    • Garg, V.1
  • 3
    • 0022338201 scopus 로고
    • Rubella screening and vaccination follow-up by a hospital employee health office
    • Kohl HW III. Rubella screening and vaccination follow-up by a hospital employee health office. Am J Infect Control 13(3):124-127, 1985.
    • (1985) Am J Infect Control , vol.13 , Issue.3 , pp. 124-127
    • Kohl Iii, H.W.1
  • 4
    • 0034489345 scopus 로고    scopus 로고
    • Teratogenic effects of dilantin on thoraco-abdominal organs of developing chick embryos
    • Singh M, Shah GL, Singh KP. Teratogenic effects of dilantin on thoraco-abdominal organs of developing chick embryos. Indian J Exp Biol 38(10):1026-1030, 2000.
    • (2000) Indian J Exp Biol , vol.38 , Issue.10 , pp. 1026-1030
    • Singh, M.1    Shah, G.L.2    Singh, K.P.3
  • 5
    • 0027207498 scopus 로고
    • Cardiac teratogenesis of halogenated hydrocarbon-contaminated drinking water
    • Dawson BV, Johnson PD, Goldberg SJ, Ulreich JB. Cardiac teratogenesis of halogenated hydrocarbon-contaminated drinking water. J Am Coll Cardiol 21(6):1466-1472, 1993.
    • (1993) J Am Coll Cardiol , vol.21 , Issue.6 , pp. 1466-1472
    • Dawson, B.V.1    Johnson, P.D.2    Goldberg, S.J.3    Ulreich, J.B.4
  • 6
    • 38049183155 scopus 로고    scopus 로고
    • Maternal diabetes induces congenital heart defects in mice by altering the expression of genes involved in cardiovascular development
    • Kumar SD, Dheen ST, Tay SS. Maternal diabetes induces congenital heart defects in mice by altering the expression of genes involved in cardiovascular development. Cardiovasc Diabetol 6:34, 2007.
    • (2007) Cardiovasc Diabetol , vol.6 , pp. 34
    • Kumar, S.D.1    Dheen, S.T.2    Tay, S.S.3
  • 7
    • 0038707943 scopus 로고    scopus 로고
    • Cardiac chamber formation: Development, genes, and evolution
    • Moorman AF, Christoffels S. Cardiac chamber formation: Development, genes, and evolution. Physiol Rev 83(4):1223-1267, 2003.
    • (2003) Physiol Rev , vol.83 , Issue.4 , pp. 1223-1267
    • Moorman, A.F.1    Christoffels, S.2
  • 9
    • 33847297490 scopus 로고    scopus 로고
    • Combinatorial signaling in the heart orchestrates cardiac induction, lineage specification and chamber formation
    • Dunwoodie SL. Combinatorial signaling in the heart orchestrates cardiac induction, lineage specification and chamber formation. Semin Cell Dev Biol 18(1):54-66, 2007.
    • (2007) Semin Cell Dev Biol , vol.18 , Issue.1 , pp. 54-66
    • Dunwoodie, S.L.1
  • 10
    • 0038485530 scopus 로고    scopus 로고
    • Heart development: Molecular insights into cardiac specification and early morphogenesis
    • Brand T. Heart development: molecular insights into cardiac specification and early morphogenesis. Developmental Biology 258(1):1-19, 2003.
    • (2003) Developmental Biology , vol.258 , Issue.1 , pp. 1-19
    • Brand, T.1
  • 11
    • 1242342762 scopus 로고    scopus 로고
    • Development gone awry congenital heart disease
    • Gruber PJ, Epstein JA. Development gone awry congenital heart disease. Circ Res 94(3):273-283, 2004.
    • (2004) Circ Res , vol.94 , Issue.3 , pp. 273-283
    • Gruber, P.J.1    Epstein, J.A.2
  • 12
    • 33749361499 scopus 로고    scopus 로고
    • Gene regulatory networks in the evolution and development of the heart
    • Olson EN. Gene regulatory networks in the evolution and development of the heart. Science 313(5795):1922-1927, 2006.
    • (2006) Science , vol.313 , Issue.5795 , pp. 1922-1927
    • Olson, E.N.1
  • 15
    • 42149159492 scopus 로고    scopus 로고
    • Wnt signaling: An essential regulator of cardiovascular differentiation, morphogenesis and progenitor self-renewal
    • Cohen ED, Tian Y, Morrisey EE. Wnt signaling: An essential regulator of cardiovascular differentiation, morphogenesis and progenitor self-renewal. Development 135(5):789-798, 2008.
    • (2008) Development , vol.135 , Issue.5 , pp. 789-798
    • Cohen, E.D.1    Tian, Y.2    Morrisey, E.E.3
  • 16
    • 39149107801 scopus 로고    scopus 로고
    • Understanding the role of transforming growth factor-beta signaling in the heart: Overview of studies using genetic mouse models
    • Xiao H, Zhang YY. Understanding the role of transforming growth factor-beta signaling in the heart: overview of studies using genetic mouse models. Clin Exp Pharmacol Physiol 35(3):335-341, 2008.
    • (2008) Clin Exp Pharmacol Physiol , vol.35 , Issue.3 , pp. 335-341
    • Xiao, H.1    Zhang, Y.Y.2
  • 17
    • 39949084472 scopus 로고    scopus 로고
    • Target-dependent inhibition of sympathetic neuron growth via modulation of a BMP signaling pathway
    • Moon JI, Birren SJ. Target-dependent inhibition of sympathetic neuron growth via modulation of a BMP signaling pathway. Dev Biol 315(2):404-417, 2008.
    • (2008) Dev Biol , vol.315 , Issue.2 , pp. 404-417
    • Moon, J.I.1    Birren, S.J.2
  • 19
    • 33749361499 scopus 로고    scopus 로고
    • Gene regulatory networks in the evolution and development of the heart
    • Olson EN. Gene regulatory networks in the evolution and development of the heart. Science. 313(5795):1922-1927, 2006.
    • (2006) Science , vol.313 , Issue.5795 , pp. 1922-1927
    • Olson, E.N.1
  • 20
    • 34347378871 scopus 로고    scopus 로고
    • Signal transduction in early heart development (II): Ventricular chamber specification, trabeculation, and heart valve formation
    • Wagner M, Siddiqui MA. Signal transduction in early heart development (II): Ventricular chamber specification, trabeculation, and heart valve formation. Exp Biol Med (Maywood) 232(7):866-880, 2007. (Pubitemid 47026792)
    • (2007) Experimental Biology and Medicine , vol.232 , Issue.7 , pp. 866-880
    • Wagner, M.1    Siddiqui, M.A.Q.2
  • 21
    • 4444320851 scopus 로고    scopus 로고
    • Heart valve development: Endothelial cell signaling and differentiation
    • Armstrong EJ, Bischoff J. Heart valve development: Endothelial cell signaling and differentiation. Circ Res 95(5):459-470, 2004.
    • (2004) Circ Res , vol.95 , Issue.5 , pp. 459-470
    • Armstrong, E.J.1    Bischoff, J.2
  • 22
    • 29144480824 scopus 로고    scopus 로고
    • Ras-related signaling pathways in valve development: Ebb and flow
    • Yutzey KE, Colbert M, Robbins J. Ras-related signaling pathways in valve development: Ebb and flow. Physiology (Bethesda) 20:390-397, 2005.
    • (2005) Physiology (Bethesda) , vol.20 , pp. 390-397
    • Yutzey, K.E.1    Colbert, M.2    Robbins, J.3
  • 24
  • 26
    • 42549118076 scopus 로고    scopus 로고
    • Wnt3a-mediated chemo-repulsion controls movement patterns of cardiac progenitors and requires RhoA function
    • Yue Q, Wagstaff L, Yang X, Weijer C, Münsterberg A. Wnt3a-mediated chemo-repulsion controls movement patterns of cardiac progenitors and requires RhoA function. Development 135(6):1029-1037, 2008.
    • (2008) Development , vol.135 , Issue.6 , pp. 1029-1037
    • Yue, Q.1    Wagstaff, L.2    Yang, X.3    Weijer, C.4    Münsterberg, A.5
  • 27
    • 37449010541 scopus 로고    scopus 로고
    • Epstein JA.The multifaceted role of Notch in cardiac development and disease
    • High FA, Epstein JA.The multifaceted role of Notch in cardiac development and disease. Nat Rev Genet 9(1):49-61, 2008.
    • (2008) Nat Rev Genet , vol.9 , Issue.1 , pp. 49-61
    • High, F.A.1
  • 33
    • 34250305402 scopus 로고    scopus 로고
    • Genetic basis for congenital heart defects. Current knowledge: A scientific statement from the American Heart Association Congenital Cardiac Defects Committee
    • Council on Cardiovascular Disease in the Young. Endorsed by the American Academy of Pediatrics
    • Pierpont ME, Basson CT, Benson Jr DW, Gelb BD, Giglia TM, Goldmuntz E, McGee G, Sable CA, Srivastava D, Webb CL. Genetic basis for congenital heart defects. Current knowledge: A scientific statement from the American Heart Association Congenital Cardiac Defects Committee, Council on Cardiovascular Disease in the Young. Endorsed by the American Academy of Pediatrics. Circulation 115(23):3015-3038, 2007.
    • (2007) Circulation , vol.115 , Issue.23 , pp. 3015-3038
    • Pierpont, M.E.1    Basson, C.T.2    Benson Jr., D.W.3    Gelb, B.D.4    Giglia, T.M.5    Goldmuntz, E.6    McGee, G.7    Sable, C.A.8    Srivastava, D.9    Webb, C.L.10
  • 35
    • 39749191367 scopus 로고    scopus 로고
    • The developmental genetics of congenital heart disease
    • Bruneau BG. The developmental genetics of congenital heart disease. Nature 451(7181):943-948, 2008.
    • (2008) Nature , vol.451 , Issue.7181 , pp. 943-948
    • Bruneau, B.G.1
  • 36
    • 32944468029 scopus 로고    scopus 로고
    • Congenital heart diseases in small animals: Part I. Genetic pathways and potential candidate genes
    • DOI 10.1016/j.tvjl.2005.02.008, PII S1090023305000407
    • Hyun C, Lavulo L. Congenital heart diseases in small animals: Part I. Genetic pathways and potential candidate genes. The Veterinary Journal 171(2):245-255, 2006. (Pubitemid 43257228)
    • (2006) Veterinary Journal , vol.171 , Issue.2 , pp. 245-255
    • Hyun, C.1    Lavulo, L.2
  • 37
    • 0034931034 scopus 로고    scopus 로고
    • Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation
    • Hiroi Y, Kudoh S, Monzen K, Ikeda Y, Yazaki Y, Nagai R, et al. Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation. Nat. Genet 28(3): 276-280, 2001.
    • (2001) Nat. Genet , vol.28 , Issue.3 , pp. 276-280
    • Hiroi, Y.1    Kudoh, S.2    Monzen, K.3    Ikeda, Y.4    Yazaki, Y.5    Nagai, R.6
  • 38
    • 0035923555 scopus 로고    scopus 로고
    • NKX2.5 mutations in patients with tetralogy of fallot
    • Goldmuntz E, Geiger E, Benson DW. NKX2.5 mutations in patients with tetralogy of fallot. Circulation 104(21): 2565-2568, 2001.
    • (2001) Circulation , vol.104 , Issue.21 , pp. 2565-2568
    • Goldmuntz, E.1    Geiger, E.2    Benson, D.W.3
  • 40
    • 11144357335 scopus 로고    scopus 로고
    • Nkx2-5 pathways and congenital heart disease: Loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block
    • Pashmforoush M, Lu JT, Chen H, Amand TS, Kondo R, Pradervand S., et al. Nkx2-5 pathways and congenital heart disease: loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block. Cell 117(3):373-386, 2004.
    • (2004) Cell , vol.117 , Issue.3 , pp. 373-386
    • Pashmforoush, M.1    Lu, J.T.2    Chen, H.3    Amand, T.S.4    Kondo, R.5    Pradervand, S.6
  • 41
    • 4644358238 scopus 로고    scopus 로고
    • GATA4 is a dosage-sensitive regulator of cardiac morphogenesis
    • Pu WT, Ishiwata T, Juraszek AL, Ma Q, Izumo S. GATA4 is a dosage-sensitive regulator of cardiac morphogenesis. Dev Biol 275(1):235-244, 2004.
    • (2004) Dev Biol , vol.275 , Issue.1 , pp. 235-244
    • Pu, W.T.1    Ishiwata, T.2    Juraszek, A.L.3    Ma, Q.4    Izumo, S.5
  • 44
    • 42149146800 scopus 로고    scopus 로고
    • Notch2 isrequired for the proliferation of cardiac neural crest-derived smooth muscle cells
    • VaradkarP,KramanM,DespresD,MaG, LozierJ,McCrightB. Notch2 isrequired for the proliferation of cardiac neural crest-derived smooth muscle cells. Dev Dyn. 237(4):1144-1152, 2008.
    • (2008) Dev Dyn. , vol.237 , Issue.4 , pp. 1144-1152
    • Varadkar, P.1    Kraman, M.2    Despres, D.3    Ma, G.4    Lozier, J.5    McCright, B.6
  • 45
    • 34548859546 scopus 로고    scopus 로고
    • Monitoring Notch1 activity in development: Evidence for a feedback regulatory loop
    • Del Monte G, Grego-Bessa J, González-Rajal A, Bolós V, De La Pompa JL. Monitoring Notch1 activity in development: evidence for a feedback regulatory loop. Dev Dyn. 236(9):2594-2614, 2007.
    • (2007) Dev Dyn. , vol.236 , Issue.9 , pp. 2594-2614
    • Del Monte, G.1    Grego-Bessa, J.2    González-Rajal, A.3    Bolós, V.4    De La Pompa, J.L.5
  • 47
    • 34447632855 scopus 로고    scopus 로고
    • Mef2ca is required in cranial neural crest to effect Endothelin 1 signaling in zebrafish
    • Miller CT, Swartz ME, Khuu PA, Walker MB, Eberhart JK, Kimmel CB. mef2ca is required in cranial neural crest to effect Endothelin 1 signaling in zebrafish. Dev Biol 308(1):144-157, 2007.
    • (2007) Dev Biol , vol.308 , Issue.1 , pp. 144-157
    • Miller, C.T.1    Swartz, M.E.2    Khuu, P.A.3    Walker, M.B.4    Eberhart, J.K.5    Kimmel, C.B.6
  • 48
    • 34250371043 scopus 로고    scopus 로고
    • Activation of p38/MEF2C pathway by all-trans retinoic acid in cardiac myoblasts
    • DOI 10.1016/j.lfs.2007.04.037, PII S002432050700344X
    • Ren X, Li Y, Ma X, Zheng L, Xu Y, Wang J. Activation of p38/MEF2C pathway by all-trans retinoic acid in cardiac myoblasts. Life Sci 81(2):89-96, 2007. (Pubitemid 46921175)
    • (2007) Life Sciences , vol.81 , Issue.2 , pp. 89-96
    • Ren, X.1    Li, Y.2    Ma, X.3    Zheng, L.4    Xu, Y.5    Wang, J.6
  • 51
    • 0037146606 scopus 로고    scopus 로고
    • Breakthrough of the year: Small RNAs make big splash
    • Couzin J. Breakthrough of the year: Small RNAs make big splash. Science 298(5602): 2296-2297, 2002.
    • (2002) Science , vol.298 , Issue.5602 , pp. 2296-2297
    • Couzin, J.1
  • 54
    • 33845601726 scopus 로고    scopus 로고
    • MicroRNAs and their regulatory roles in animals and plants
    • Zhang B, Wang Q, Pan X. MicroRNAs and their regulatory roles in animals and plants. J Cell Physiol 210(2): 279-289, 2007.
    • (2007) J Cell Physiol , vol.210 , Issue.2 , pp. 279-289
    • Zhang, B.1    Wang, Q.2    Pan, X.3
  • 55
    • 34147153781 scopus 로고    scopus 로고
    • Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2
    • Zhao Y, Ransom JF, Li A, et al. Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell 129(2):303-317, 2007.
    • (2007) Cell , vol.129 , Issue.2 , pp. 303-317
    • Zhao, Y.1    Ransom, J.F.2    Li, A.3
  • 56
    • 22444437609 scopus 로고    scopus 로고
    • Serum sponse factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis
    • Zhao Y, Samal E, Srivastava D. Serum sponse factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature 36(7048):214-220, 2005.
    • (2005) Nature , vol.36 , Issue.7048 , pp. 214-220
    • Zhao, Y.1    Samal, E.2    Srivastava, D.3
  • 57
    • 30044437240 scopus 로고    scopus 로고
    • MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling
    • Kwon C, Han Z, Olson EN, et al. MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling. Proc Natl Acad Sci USA 102(52): 18986-18991, 2005.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.52 , pp. 18986-18991
    • Kwon, C.1    Han, Z.2    Olson, E.N.3
  • 58
    • 17444403604 scopus 로고    scopus 로고
    • GottesmanArturas Petronis. Phenotypic differences in genetically identical organisms: The epigenetic perspective
    • Albert HC, Wong II. Gottesman,Arturas Petronis. Phenotypic differences in genetically identical organisms: the epigenetic perspective. Human Molecular Genetics 14(1):R11-R18, 2005.
    • (2005) Human Molecular Genetics , vol.14 , Issue.1
    • Albert, H.C.1    Wong, I.I.2
  • 59
    • 33745513685 scopus 로고    scopus 로고
    • Epigenetic modification is central to genome repro-gramming in somatic cell nuclear transfer
    • Armstrong L, Lako M, Dean W, Stojkovic M. Epigenetic modification is central to genome repro-gramming in somatic cell nuclear transfer. Stem Cells 24(4):805-814, 2006.
    • (2006) Stem Cells , vol.24 , Issue.4 , pp. 805-814
    • Armstrong, L.1    Lako, M.2    Dean, W.3    Stojkovic, M.4
  • 60
    • 34447104563 scopus 로고    scopus 로고
    • Mutator pathways unleashed by epigenetic silencing in human cancer
    • Jacinto FV: Esteller M. Mutator pathways unleashed by epigenetic silencing in human cancer. Muta-genesi 22(4):247-253, 2007.
    • (2007) Muta-genesi , vol.22 , Issue.4 , pp. 247-253
    • Jacinto, F.V.1    Esteller, M.2
  • 61
    • 33846798106 scopus 로고    scopus 로고
    • Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms
    • Aird WC. Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms. Circ Res 100:158-173, 2007.
    • (2007) Circ Res , vol.100 , pp. 158-173
    • Aird, W.C.1
  • 62
    • 35148835708 scopus 로고    scopus 로고
    • Genetics of cardiovascular diseases: From single mutations to the whole genome
    • Cambien F, Tiret L. Genetics of cardiovascular diseases: From single mutations to the whole genome. Circulation 116:1714-1724, 2007.
    • (2007) Circulation , vol.116 , pp. 1714-1724
    • Cambien, F.1    Tiret, L.2
  • 63
    • 10044237833 scopus 로고    scopus 로고
    • Adult congenital heart disease: A cardiovascular area of growth in urgent need of additional resource allocation
    • Gatzoulis MA. Adult congenital heart disease: a cardiovascular area of growth in urgent need of additional resource allocation. Int J Cardiol 97 (suppl 1):1-2, 2004.
    • (2004) Int J Cardiol , vol.97 , Issue.SUPPL. 1 , pp. 1-2
    • Gatzoulis, M.A.1
  • 64
    • 21344444848 scopus 로고    scopus 로고
    • The adult with congenital heart disease, born to be bad?
    • Warnes CA, The adult with congenital heart disease, born to be bad? JACC 46(1):1-8, 2005.
    • (2005) JACC , vol.46 , Issue.1 , pp. 1-8
    • Warnes, C.A.1
  • 65
    • 33750445938 scopus 로고    scopus 로고
    • Genetic approaches to coronary heart disease
    • Cohen JC. Genetic approaches to coronary heart disease. JACC 48(9)suppl A 7:A10-4, 2006.
    • (2006) JACC , vol.48 , Issue.9 SUPPL. A 7
    • Cohen, J.C.1
  • 66
    • 38749149611 scopus 로고    scopus 로고
    • Genome-wide association study identifies genes for biomark-ers of cardiovascular disease: Serum urate and dyslipidemia
    • Wallace C, Newhouse SJ, Braund P, et al. Genome-wide association study identifies genes for biomark-ers of cardiovascular disease: Serum urate and dyslipidemia. The American Journal of Human Genetics 82:139-149, 2008.
    • (2008) The American Journal of Human Genetics , vol.82 , pp. 139-149
    • Wallace, C.1    Newhouse, S.J.2    Braund, P.3
  • 67
    • 35448996964 scopus 로고    scopus 로고
    • Bioinformatics approaches to quadruplex sequence location
    • Todd AK. Bioinformatics approaches to quadruplex sequence location. Methods 43(4):246-251, 2007.
    • (2007) Methods , vol.43 , Issue.4 , pp. 246-251
    • Todd, A.K.1
  • 68
    • 36549005426 scopus 로고    scopus 로고
    • Conditional gene silencing in mammalian cells mediated by a stress-inducible promoter
    • Yang W, Paschen W. Conditional gene silencing in mammalian cells mediated by a stress-inducible promoter. Biochemical and Biophysical Research Communications 365(3):521-527, 2008.
    • (2008) Biochemical and Biophysical Research Communications , vol.365 , Issue.3 , pp. 521-527
    • Yang, W.1    Paschen, W.2


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