The endothelin-1 pathway and the development of cardiovascular defects in the haemodynamically challenged chicken embryo

Journal of Vascular Research

Volumn 45, Issue 1, 2007, Pages 54-68

  Groenendijk, Bianca C W ^a,d   Stekelenburg De Vos, Sandra ^b   Vennemann, Peter ^c   Wladimiroff, Juriy W ^b   Nieuwstadt, Frans T M ^c   Lindken, Ralph ^c   Westerweel, Jerry ^c   Hierck, Beerend P ^a   Ursem, Nicolette T C ^b   Poelmann, Robert E ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^d ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Atrioventricular function; Blood flow velocity; Cardiac malformation; Chicken embryo; Endothelin 1; Endothelin A receptor; Endothelin B receptor; Hemodynamics

Indexed keywords

CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; ENDOTHELIN RECEPTOR ANTAGONIST; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; N ACETYL 10,11 DIHYDRO 5H DIBENZO[A,D]CYCLOHEPTEN 5 YLGLYCYLLEUCYLASPARTYLISOLEUCYLISOLEUCYLTRYPTOPHAN;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD FLOW VELOCITY; CARDIOVASCULAR FUNCTION; CARDIOVASCULAR MALFORMATION; CHICK EMBRYO; CIRCULATION; CLIP; CONTROLLED STUDY; DIASTOLE; DOPPLER ECHOGRAPHY; EMBRYO; EMBRYO DEVELOPMENT; GENE EXPRESSION REGULATION; HEART; HEART MUSCLE; HEART VENTRICLE FILLING; HEMODYNAMICS; MORPHOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; YOLK SAC;

ANIMALS; ASPARTIC ENDOPEPTIDASES; BLOOD FLOW VELOCITY; CARDIAC OUTPUT; CARDIOVASCULAR ABNORMALITIES; CELLS, CULTURED; CHICK EMBRYO; ECHOCARDIOGRAPHY; ENDOTHELIN-1; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; HEART RATE; HEMODYNAMICS; LASER-DOPPLER FLOWMETRY; LIGATION; METALLOENDOPEPTIDASES; MYOCARDIUM; OLIGOPEPTIDES; PEPTIDES, CYCLIC; PIPERIDINES; RECEPTORS, ENDOTHELIN; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; VEINS; VENTRICULAR FUNCTION; YOLK SAC;

EID: 37249086058     PISSN: 10181172     EISSN: None     Source Type: Journal    
DOI: 10.1159/000109077     Document Type: Article

References (45)

1. Hove JR, Koster RW, Forouhar AS, Acevedo-Bolton G, Fraser SE, Gharib M: Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis. Nature 2003;421:172-177.
2. Hogers B, DeRuiter MC, Gittenberger-de Groot AC, Poelmann RE: Extraembryonic venous obstructions lead to cardiovascular malformations and can be embryolethal. Cardiovasc Res 1999;41:87-99.
3. McCormick SM, Eskin SG, McIntire LV, Teng CL, Lu CM, Russell CG, Chittur KK: DNA microarray reveals changes in gene expression of shear stressed human umbilical vein endothelial cells. Proc Natl Acad Sci USA 2001;98:8955-8960.
4. Dekker RJ, Van Soest S, Fontijn RD, Salamanca S, de Groot PG, VanBavel E, Pannekoek H, Horrevoets AJG: Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Krüppel-like factor (KLF2). Blood 2002;100:1689-1698.
5. Groenendijk BCW, Hierck BP, Gittenbergerde Groot AC, Poelmann RE: Development-related changes in the expression of shear stress responsive genes KLF-2, ET-1, and NOS-3 in the developing cardiovascular system of chicken embryos. Dev Dyn 2004;230:57-68.
6. Hamburger V, Hamilton HL: A series of normal stages in the development of the chick embryo. J Morphol 1951;88:49-92.
7. Hogers B, DeRuiter MC, Gittenberger-de Groot AC, Poelmann RE: Unilateral vitelline vein ligation alters intracardiac blood flow patterns and morphogenesis in the chick embryo. Circ Res 1997;80:473-481.
8. Stekelenburg-de Vos S, Ursem NTC, Hop WCJ, Wladimiroff JW, Gittenberger-de Groot AC, Poelmann RE: Acutely altered hemodynamics following venous obstruction in the early chick embryo. J Exp Biol 2003;206:1051-1057.
9. Groenendijk BCW, Hierck BP, Vrolijk J, Baiker M, Pourquie MJBM, Gittenberger-de Groot AC, Poelmann RE: Changes in shear stress-related gene expression after experimentally altered venous return in the chicken embryo. Circ Res 2005;96:1291-1298.
10. Stekelenburg-de Vos S, Steendijk P, Ursem NT, Wladimiroff JW, Delfos R, Poelmann RE: Systolic and diastolic ventricular function assessed by pressure-volume loops in the stage 21 venous clipped chick embryo. Pediatr Res 2005;57:16-21.
11. Ursem NTC, Stekelenburg-de Vos S, Wladimiroff JW, Poelmann RE, Gittenberger-de Groot AC, Hu N, Clark EB: Ventricular diastolic filling characteristics in stage-24 chick embryos after extra-embryonic venous obstruction. J Exp Biol 2004;207:1487-1490.
12. Kurihara Y, Kurihara H, Oda H, Maemura K, Nagai R, Ishikawa T, Yazaki Y: Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1. J Clin Invest 1995;96:293-300.
13. Yanagisawa H, Yanagisawa M, Kapur RP, Richardson JA, Williams SC, Clouthier DE, de Wit D, Emoto N, Hammer RE: Dual genetic pathways of endothelin-mediated intercellular signaling revealed by targeted disruption of endothelin converting enzyme-1 gene. Development 1998;125:825-836.
14. Clouthier DE, Hosoda K, Richardson JA, Williams SC, Yanagisawa H, Kuwaki T, Kumada M, Hammer RE, Yanagisawa M: Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice. Development 1998;125:813-824.
15. Ursem NTC, Struijk PC, Poelmann RE, Gittenberger-de Groot AC, Wladimiroff JW: Dorsal aortic flow velocity in chick embryos of stage 16 to 28. Ultrasound Med Biol 2001;27:919-924.
16. Nakazawa M, Clark EB, Hu N, Wispe J: Effect of environmental hypothermia in vitelline artery blood pressure and vascular resistance in the stage 18, 21, and 24 chick embryo. Pediatr Res 1985;19:651-654.
17. Hu N, Connuck DM, Keller BB, Clark EB: Diastolic filling characteristics in the stage 12 to 27 chick embryo ventricle. Pediatr Res 1991;29:334-337.
18. Vennemann P, Kiger KT, Lindken R, Groenendijk BCW, Stekelenburg-de Vos S, ten Hagen TLM, Ursem NTC, Poelmann RE, Westerweel J, Hierck BP: In vivo micro particle image velocimetry measurements of blood-plasma in the embryonic avian heart. J Biomech 2006;39:1191-1200.
19. Meinhart C, Wereley S, Santiago J: A PIV algorithm for estimating time-averaged velocity fields. J Fluids Eng 2000;122:285-289.
20. Tsukada T, Tippens D, Gordon D, Ross R, Gown AM: HHF35, a muscle-actin-specific monoclonal antibody. I. Immunocytochemical and biochemical characterization. Am J Pathol 1987;126:51-60.
21. Hierck BP, Poelmann RE, van Iperen L, Brouwer A, Gittenberger-de Groot AC: Differential expression of 6 and other subunits of laminin binding integrins during development of the murine heart. Dev Dyn 1996;206:100-111.
22. Hierck BP, Molin DGM, Boot MJ, Poelmann RE, Gittenberger-de Groot AC: A chicken model for DGCR6 as a modifier gene in the DiGeorge critical region. Pediatr Res 2004;56:440-448.
23. Rozen S, Skaletsky H: Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol 2000;132:365-386.
24. Pfaffl MW: A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001;29:2002-2007.
25. Broekhuizen MLA, Mast F, Struijk, van der Bie W, Mulder PGH, Gittenberger-de Groot AC, Wladimiroff J: Hemodynamic parameters of stage 20 to stage 35 chick embryo. Pediatr Res 1993;34:44-46.
26. Hu N, Clark EB: Hemodynamics of the stage 12 to stage 29 chick embryo. Circ Res 1989;65:1665-1670.
27. Yoshigi M, Hu N, Keller BB: Dorsal aortic impedance in stage 24 chick embryo following acute changes in circulating blood volume. Am J Physiol 1996;270:H1597-H1606.
28. Vrancken Peeters M-PFM, Mentink MMT, Poelmann RE, Gittenberger-de Groot AC: Cytokeratins as a marker for epicardial formation in the quail embryo. Anat Embryol 1995;191:503-508.
29. Hosoda K, Nakao K, Hiroshi A, Suga S, Ogawa Y, Mukoyama M, Shirakami G, Saito Y, Nakanishi S, Imura H: Cloning and expression of human endothelin-1 receptor cDNA. FEBS Lett 1991;287:23-26.
30. Haynes WG, Strachan FE, Webb DJ: Endothelin ETA and ETB receptors cause vasoconstriction of human resistance and capacitance vessels in vivo. Circulation 1995;92:357-363.
31. Tsukahara H, Ende H, Magazine HI, Bahou WF, Goligorsky MS: Molecular and functional characterization of the non-isopeptide-selective ETB receptor in endothelial cells: receptor coupling to nitric oxide synthase. J Biol Chem 1994;269:21778-21785.
32. Verhaar MC, Strachan FE, Newby DE, Cruden NL, Koomans HA, Rabelink TJ, Webb DJ: Endothelin-A receptor antagonist-mediated vasodilatation is attenuated by inhibition of nitric oxide synthesis and by endothelin-B receptor blockade. Circulation 1998;97:752-756.
33. Berthiaume N, Yanagisawa M, Labonte J, D'Orleans-Juste P: Heterozygous knock-out of ET(B) receptors induces BQ-123-sensitive hypertension in the mouse. Hypertension 2000;36:1002-1007.
34. D'Orleans-Juste P, Labonte J, Bkaily G, Choufani S, Plante M, Honore JC: Function of the endothelin(B) receptor in cardiovascular physiology and pathophysiology. Pharmacol Ther 2002;95:221-238.
35. Hirata Y, Emori T, Eguchi S, Kanno K, Imai T, Ohta K, Marumo F: Endothelin receptor subtype B mediates synthesis of nitric oxide by cultured bovine endothelial cells. J Clin Invest 1993;91:1367-1373.
36. + exchanger-mediated effect. Am J Physiol Heart Circ Physiol 2003;284:H1332-H1339.
37. Marsault R, Feolde E, Frelin C: Receptor externalization determines sustained contractile responses to endothelin-1 in the rat aorta. Am J Physiol 1993;264:C687-C693.
38. Kajio F, Nakazawa M: Vascular effects of endothelin-1 in stage 21 chick embryos. Heart Vessels 1997;12:300-305.
39. Kelso EJ, McDermott BJ, Silke B, Spiers JP: EndothelinA receptor subtype mediates endothelin-induced contractility in left ventricular cardiomyocytes isolated from rabbit myocardium. J Pharmacol Exp Ther 2000;294:1047-1052.
40. Vierhapper H, Wagner O, Nowotny P, Waldhausl W: Effect of endothelin-1 in man. Circulation 1990;81:1415-1418.
41. Sirviö ML, Metsärinne K, Saijonmaa O, Fyhrquist F: Tissue distribution and half-life of I-125 endothelin in the rat - importance of pulmonary clearance. Biochem Biophys Res Commun 1990;167:1191-1195.
42. Guarda E, Katwa LC, Myers PR, Tyagi SC, Weber KT: Effects of endothelins on collagen turnover in cardiac fibroblasts. Cardiovasc Res 1993;27:2130-2134.
43. Fujisaki H, Ito H, Hirata Y, Tanaka M, Hata M, Lin MH, Adachi S, Akimoto H, Marumo F, Hiroe M: Natriuretic peptides inhibit angiotensin II-induced proliferation of rat cardiac fibroblasts by blocking endothelin-1 gene-expression. J Clin Invest 1995;96:1059-1065.
44. Hogers B, Gittenberger-de Groot AC, DeRuiter MC, Mentink MMT, Poelmann RE: Cardiac inflow malformations are more lethal and precede cardiac outflow malformations: chick embryonic venous clip model; in Hogers B (ed): The Role of Blood Flow in Normal and Abnormal Heart Development. Wageningen, Ponsen & Looijen BV, 1998, pp 79-100.
45. Lie-Venema H, Gittenberger-de Groot AC, van Empel LJP, Boot MJ, Kerkdijk H, de Kant E, DeRuiter MC: Ets-1 and Ets-2 transcription factors are essential for normal coronary and myocardial development in chicken embryos. Circ Res 2003;92:749-756.