-
1
-
-
36448951632
-
Satraplatin in the treatment of hormone-refractory metastatic prostate cancer
-
Armstrong, A.J. and George, D.J. ( 2007) Satraplatin in the treatment of hormone-refractory metastatic prostate cancer. Ther Clin Risk Manag 3: 877-883.
-
(2007)
Ther Clin Risk Manag
, vol.3
, pp. 877-883
-
-
Armstrong, A.J.1
George, D.J.2
-
2
-
-
45849119070
-
New drug development in metastatic prostate cancer
-
Armstrong, A.J. and George, D.J. ( 2008) New drug development in metastatic prostate cancer. Urol Oncol 26: 430-437.
-
(2008)
Urol Oncol
, vol.26
, pp. 430-437
-
-
Armstrong, A.J.1
George, D.J.2
-
3
-
-
69249083981
-
(2009) Discovery of BMS-641988, a novel and potent inhibitor of androgen receptor signaling for the treatment of prostate cancer
-
Attar, R.M., Jure-Kunkel, M., Balog, A., Cvijic, M.E., Dell-John, J., Rizzo, C.A. et al. (2009) Discovery of BMS-641988, a novel and potent inhibitor of androgen receptor signaling for the treatment of prostate cancer. Cancer Res 69: 6522-6530.
-
Cancer Res
, vol.69
, pp. 6522-6530
-
-
Attar, R.M.1
Jure-Kunkel, M.2
Balog, A.3
Cvijic, M.E.4
Dell-John, J.5
Rizzo, C.A.6
-
4
-
-
33749345244
-
Improving the outcome of patients with castration-resistant prostate cancer through rational drug development
-
Attard, G., Sarker, D., Reid, A., Molife, R., Parker, C. and de Bono, J.S. ( 2006) Improving the outcome of patients with castration-resistant prostate cancer through rational drug development. Br J Cancer 95: 767-774.
-
(2006)
Br J Cancer
, vol.95
, pp. 767-774
-
-
Attard, G.1
Sarker, D.2
Reid, A.3
Molife, R.4
Parker, C.5
de Bono, J.S.6
-
5
-
-
67449119425
-
(2009 a) Antitumor activity with CYP 17 blockade indicates that castration-resistant prostate cancer frequently remains hormone driven
-
Attard, G., Reid, A.H., Olmos, D. and de Bono, J.S. (2009 a) Antitumor activity with CYP 17 blockade indicates that castration-resistant prostate cancer frequently remains hormone driven. Cancer Res 69: 4937-4940.
-
Cancer Res
, vol.69
, pp. 4937-4940
-
-
Attard, G.1
Reid, A.H.2
Olmos, D.3
de Bono, J.S.4
-
6
-
-
68949094223
-
Selective inhibition of CYP 17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer
-
Attard, G., Reid, A.H., A'Hern, R., Parker, C., Oommen, N.B., Folkerd, E. et al. (2009 b) Selective inhibition of CYP 17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer. J Clin Oncol 27: 3742-3748.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3742-3748
-
-
Attard, G.1
Reid, A.H.2
A'Hern, R.3
Parker, C.4
Oommen, N.B.5
Folkerd, E.6
-
7
-
-
1942534043
-
The evolution of thalidomide and its IMiD derivatives as anticancer agents
-
Bartlett, J.B., Dredge, K. and Dalgleish, A.G. ( 2004) The evolution of thalidomide and its IMiD derivatives as anticancer agents. Nat Rev Cancer 4: 314-322.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 314-322
-
-
Bartlett, J.B.1
Dredge, K.2
Dalgleish, A.G.3
-
8
-
-
54049158952
-
Systemic therapy after first-line docetaxel in metastatic castration-resistant prostate cancer
-
Beardsley, E.K. and Chi, K.N. ( 2008) Systemic therapy after first-line docetaxel in metastatic castration-resistant prostate cancer. Curr Opin Support Palliat Care 2: 161-166.
-
(2008)
Curr Opin Support Palliat Care
, vol.2
, pp. 161-166
-
-
Beardsley, E.K.1
Chi, K.N.2
-
9
-
-
24044457933
-
ASCENT: the androgen-independent prostate cancer study of calcitriol enhancing taxotere
-
Beer, T.M. ( 2005) ASCENT: the androgen-independent prostate cancer study of calcitriol enhancing taxotere. BJU Int 96: 508-513.
-
(2005)
BJU Int
, vol.96
, pp. 508-513
-
-
Beer, T.M.1
-
10
-
-
33947610197
-
Double-blinded randomized study of high-dose calcitriol plus docetaxel compared with placebo plus docetaxel in androgen-independent prostate cancer: a report from the ASCENT Investigators
-
Beer, T.M., Ryan, C.W., Venner, P.M., Petrylak, D.P., Chatta, G.S., Ruether, J.D. et al. (2007) Double-blinded randomized study of high-dose calcitriol plus docetaxel compared with placebo plus docetaxel in androgen-independent prostate cancer: a report from the ASCENT Investigators. J Clin Oncol 25: 669-674.
-
(2007)
J Clin Oncol
, vol.25
, pp. 669-674
-
-
Beer, T.M.1
Ryan, C.W.2
Venner, P.M.3
Petrylak, D.P.4
Chatta, G.S.5
Ruether, J.D.6
-
11
-
-
66249105438
-
Phase I trial of ipilimumab (IPI) alone and in combination with radiotherapy (XRT) in patients with metastatic castration resistant prostate cancer (mCRPC)
-
(Suppl May abstr
-
Beer, T.M., Slovin, S.F., Higano, C.S., Tejwani, S., Dorff, T.B., Stankevich, E. et al. (2008) Phase I trial of ipilimumab (IPI) alone and in combination with radiotherapy (XRT) in patients with metastatic castration resistant prostate cancer (mCRPC). J Clin Oncol 26(Suppl May 20): abstr 5004.
-
(2008)
J Clin Oncol
, vol.26
, Issue.20
, pp. 5004
-
-
Beer, T.M.1
Slovin, S.F.2
Higano, C.S.3
Tejwani, S.4
Dorff, T.B.5
Stankevich, E.6
-
12
-
-
67449092662
-
(2009 a) Predictive modelling in hormone-refractory prostate cancer (HRPC)
-
Bellmunt, J., Carles, J. and Albanell, J. (2009 a) Predictive modelling in hormone-refractory prostate cancer (HRPC). Clin Transl Oncol 11: 82-85.
-
Clin Transl Oncol
, vol.11
, pp. 82-85
-
-
Bellmunt, J.1
Carles, J.2
Albanell, J.3
-
13
-
-
67650506761
-
(2009 b) Optimal management of metastatic renal cell carcinoma: an algorithm for treatment
-
Bellmunt, J., Flodgren, P., Roigas, J. and Oudard, S. (2009 b) Optimal management of metastatic renal cell carcinoma: an algorithm for treatment. BJU Int 104: 10-18.
-
BJU Int
, vol.104
, pp. 10-18
-
-
Bellmunt, J.1
Flodgren, P.2
Roigas, J.3
Oudard, S.4
-
14
-
-
69349101825
-
(2009 c) Recent progress and pitfalls in testing novel agents in castration-resistant prostate cancer
-
Bellmunt, J., Rosenberg, J.E. and Choueiri, T.K. (2009 c) Recent progress and pitfalls in testing novel agents in castration-resistant prostate cancer. Eur Urol 56: 606-608.
-
Eur Urol
, vol.56
, pp. 606-608
-
-
Bellmunt, J.1
Rosenberg, J.E.2
Choueiri, T.K.3
-
15
-
-
23244451398
-
Epothilones and the next generation of phase III trials for prostate cancer
-
Bhandari, M.S. and Hussain, M. ( 2005) Epothilones and the next generation of phase III trials for prostate cancer. BJU Int 96: 296-302.
-
(2005)
BJU Int
, vol.96
, pp. 296-302
-
-
Bhandari, M.S.1
Hussain, M.2
-
16
-
-
45149124792
-
Effects of denosumab on bone mineral density and bone turnover in postmenopausal women
-
Bone, H.G., Bolognese, M.A., Yuen, C.K., Kendler, D.L., Wang, H., Liu, Y. et al. (2008) Effects of denosumab on bone mineral density and bone turnover in postmenopausal women. J Clin Endocrinol Metab 93: 2149-2157.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 2149-2157
-
-
Bone, H.G.1
Bolognese, M.A.2
Yuen, C.K.3
Kendler, D.L.4
Wang, H.5
Liu, Y.6
-
17
-
-
34547672621
-
Bone directed therapies for prostate cancer
-
Bradley, D.A., Hussain, M., Dipaola, R.S. and Kantoff, P. ( 2007) Bone directed therapies for prostate cancer. J Urol 178: S42-S48.
-
(2007)
J Urol
, vol.178
, pp. S42-S48
-
-
Bradley, D.A.1
Hussain, M.2
Dipaola, R.S.3
Kantoff, P.4
-
18
-
-
84993766431
-
Vorinostat in hormone refractory prostate cancer (HRPC): trial results and IL-6 analysis
-
Proceedings of the Genitourinary Cancers Symposium Abstract 211.
-
Bradley, D.A., Dunn, R., Rathkopf, D., Stadler, W.M., Wilding, G., Smith, D.C. et al. (2008) Vorinostat in hormone refractory prostate cancer (HRPC): trial results and IL-6 analysis. Proceedings of the Genitourinary Cancers Symposium, Abstract 211.
-
(2008)
-
-
Bradley, D.A.1
Dunn, R.2
Rathkopf, D.3
Stadler, W.M.4
Wilding, G.5
Smith, D.C.6
-
19
-
-
0035319658
-
Osteoprotegerin and rank ligand expression in prostate cancer
-
Brown, J.M., Corey, E., Lee, Z.D., True, L.D., Yun, T.J., Tondravi, M. et al. (2001) Osteoprotegerin and rank ligand expression in prostate cancer. Urology 57: 611-616.
-
(2001)
Urology
, vol.57
, pp. 611-616
-
-
Brown, J.M.1
Corey, E.2
Lee, Z.D.3
True, L.D.4
Yun, T.J.5
Tondravi, M.6
-
20
-
-
20044372705
-
Randomized phase II study of two doses of gefitinib in hormone-refractory prostate cancer: a trial of the National Cancer Institute of Canada-Clinical Trials Group
-
Canil, C.M., Moore, M.J., Winquist, E., Baetz, T., Pollak, M., Chi, K.N. et al. (2005) Randomized phase II study of two doses of gefitinib in hormone-refractory prostate cancer: a trial of the National Cancer Institute of Canada-Clinical Trials Group. J Clin Oncol 23: 455-460.
-
(2005)
J Clin Oncol
, vol.23
, pp. 455-460
-
-
Canil, C.M.1
Moore, M.J.2
Winquist, E.3
Baetz, T.4
Pollak, M.5
Chi, K.N.6
-
21
-
-
0037089676
-
Atrasentan, an endothelin-receptor antagonist for refractory adenocarcinomas: safety and pharmacokinetics
-
Carducci, M.A., Nelson, J.B., Bowling, M.K., Rogers, T., Eisenberger, M.A., Sinibaldi, V. et al. (2002) Atrasentan, an endothelin-receptor antagonist for refractory adenocarcinomas: safety and pharmacokinetics. J Clin Oncol 20: 2171-2180.
-
(2002)
J Clin Oncol
, vol.20
, pp. 2171-2180
-
-
Carducci, M.A.1
Nelson, J.B.2
Bowling, M.K.3
Rogers, T.4
Eisenberger, M.A.5
Sinibaldi, V.6
-
22
-
-
0037441843
-
Effect of endothelin-A receptor blockade with atrasentan on tumor progression in men with hormone-refractory prostate cancer: a randomized, phase II, placebo-controlled trial
-
Carducci, M.A., Padley, R.J., Breul, J., Vogelzang, N.J., Zonnenberg, B.A., Daliani, D.D. et al. (2003) Effect of endothelin-A receptor blockade with atrasentan on tumor progression in men with hormone-refractory prostate cancer: a randomized, phase II, placebo-controlled trial. J Clin Oncol 21: 679-689.
-
(2003)
J Clin Oncol
, vol.21
, pp. 679-689
-
-
Carducci, M.A.1
Padley, R.J.2
Breul, J.3
Vogelzang, N.J.4
Zonnenberg, B.A.5
Daliani, D.D.6
-
23
-
-
35648968713
-
A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormone-refractory prostate cancer
-
Carducci, M.A., Saad, F., Abrahamsson, P.A., Dearnaley, D.P., Schulman, C.C., North, S.A. et al. (2007) A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormone-refractory prostate cancer. Cancer 110: 1959-1966.
-
(2007)
Cancer
, vol.110
, pp. 1959-1966
-
-
Carducci, M.A.1
Saad, F.2
Abrahamsson, P.A.3
Dearnaley, D.P.4
Schulman, C.C.5
North, S.A.6
-
24
-
-
57649213265
-
(2009) The role of systemic cytotoxic therapy for prostate cancer
-
Chang, S.S. and Kibel, A.S. (2009) The role of systemic cytotoxic therapy for prostate cancer. BJU Int 103: 8-17.
-
BJU Int
, vol.103
, pp. 8-17
-
-
Chang, S.S.1
Kibel, A.S.2
-
25
-
-
38949099997
-
The AKT inhibitor perifosine in biochemically recurrent prostate cancer: a phase II California / Pittsburgh cancer consortium trial
-
Chee, K.G., Longmate, J., Quinn, D.I., Chatta, G., Pinski, J., Twardowski, P. et al. (2007) The AKT inhibitor perifosine in biochemically recurrent prostate cancer: a phase II California / Pittsburgh cancer consortium trial. Clin Genitourin Cancer 5: 433-437.
-
(2007)
Clin Genitourin Cancer
, vol.5
, pp. 433-437
-
-
Chee, K.G.1
Longmate, J.2
Quinn, D.I.3
Chatta, G.4
Pinski, J.5
Twardowski, P.6
-
26
-
-
1842612441
-
Molecular determinants of resistance to antiandrogen therapy
-
Chen, C.D., Welsbie, D.S., Tran, C., Baek, S.H., Chen, R., Vessella, R. et al. (2004) Molecular determinants of resistance to antiandrogen therapy. Nat Med 10: 33-39.
-
(2004)
Nat Med
, vol.10
, pp. 33-39
-
-
Chen, C.D.1
Welsbie, D.S.2
Tran, C.3
Baek, S.H.4
Chen, R.5
Vessella, R.6
-
27
-
-
33745821237
-
Expression of RANKL/RANK/OPG in primary and metastatic human prostate cancer as markers of disease stage and functional regulation
-
Chen, G., Sircar, K., Aprikian, A., Potti, A., Goltzman, D. and Rabbani, S.A. ( 2006) Expression of RANKL/RANK/OPG in primary and metastatic human prostate cancer as markers of disease stage and functional regulation. Cancer 107: 289-298.
-
(2006)
Cancer
, vol.107
, pp. 289-298
-
-
Chen, G.1
Sircar, K.2
Aprikian, A.3
Potti, A.4
Goltzman, D.5
Rabbani, S.A.6
-
28
-
-
77955624630
-
A phase II trial of lapatinib (GW572016) in patients with recurrent prostate cancer as evident by a rising PSA
-
(Suppl May 20): abstr
-
Chen, Y., Wilding, G., Gee, J., DiPaola, R.P., Pins, M., Carducci, M.A. et al. (2008) A phase II trial of lapatinib (GW572016) in patients with recurrent prostate cancer as evident by a rising PSA. J Clin Oncol 26(Suppl May 20): abstr 5170.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5170
-
-
Chen, Y.1
Wilding, G.2
Gee, J.3
DiPaola, R.P.4
Pins, M.5
Carducci, M.A.6
-
29
-
-
70349395222
-
(2009) Anti-androgens and androgen-depleting therapies in prostate cancer: new agents for an established target
-
Chen, Y., Clegg, N.J. and Scher, H.I. (2009) Anti-androgens and androgen-depleting therapies in prostate cancer: new agents for an established target. Lancet Oncol 10: 981-991.
-
Lancet Oncol
, vol.10
, pp. 981-991
-
-
Chen, Y.1
Clegg, N.J.2
Scher, H.I.3
-
30
-
-
24744470522
-
A phase I pharmacokinetic and pharmacodynamic study of OGX-011, a 2′-methoxyethyl antisense oligonucleotide to clusterin, in patients with localized prostate cancer
-
Chi, K.N., Eisenhauer, E., Fazli, L., Jones, E.C., Goldenberg, S.L., Powers, J. et al. (2005) A phase I pharmacokinetic and pharmacodynamic study of OGX-011, a 2′-methoxyethyl antisense oligonucleotide to clusterin, in patients with localized prostate cancer. J Natl Cancer Inst 97: 1287-1296.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 1287-1296
-
-
Chi, K.N.1
Eisenhauer, E.2
Fazli, L.3
Jones, E.C.4
Goldenberg, S.L.5
Powers, J.6
-
31
-
-
41549144309
-
A phase II study of sorafenib in patients with chemo-naive castration-resistant prostate cancer
-
Chi, K.N., Ellard, S.L., Hotte, S.J., Czaykowski, P., Moore, M., Ruether, J.D. et al. (2008 a) A phase II study of sorafenib in patients with chemo-naive castration-resistant prostate cancer. Ann Oncol 19: 746-751.
-
(2008)
Ann Oncol
, vol.19
, pp. 746-751
-
-
Chi, K.N.1
Ellard, S.L.2
Hotte, S.J.3
Czaykowski, P.4
Moore, M.5
Ruether, J.D.6
-
32
-
-
38949153810
-
A phase I study of OGX-011, a 2′-methoxyethyl phosphorothioate antisense to clusterin, in combination with docetaxel in patients with advanced cancer
-
Chi, K.N., Siu, L.L., Hirte, H., Hotte, S.J., Knox, J., Kollmansberger, C. et al. (2008 b) A phase I study of OGX-011, a 2′-methoxyethyl phosphorothioate antisense to clusterin, in combination with docetaxel in patients with advanced cancer. Clin Cancer Res 14: 833-839.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 833-839
-
-
Chi, K.N.1
Siu, L.L.2
Hirte, H.3
Hotte, S.J.4
Knox, J.5
Kollmansberger, C.6
-
33
-
-
69249203584
-
(2009 a) Castration resistant prostate cancer: from new pathophysiology to new treatment targets
-
Chi, K.N., Bjartell, A., Dearnaley, D., Saad, F., Schroder, F.H., Sternberg, C. et al. (2009 a) Castration resistant prostate cancer: from new pathophysiology to new treatment targets. Eur Urol 56: 594-605.
-
Eur Urol
, vol.56
, pp. 594-605
-
-
Chi, K.N.1
Bjartell, A.2
Dearnaley, D.3
Saad, F.4
Schroder, F.H.5
Sternberg, C.6
-
34
-
-
74949094742
-
Mature results of a randomized phase II study of OGX-011 in combination with docetaxel / prednisone versus docetaxel / prednisone in patients with metastatic castration-resistant prostate cancer
-
abstr
-
Chi, K.N., Hotte, S.J., Yu, E., Tu, D., Eigl, B., Tannock, I. et al. (2009 b) Mature results of a randomized phase II study of OGX-011 in combination with docetaxel / prednisone versus docetaxel / prednisone in patients with metastatic castration-resistant prostate cancer. J Clin Oncol 27(15s): abstr 5012.
-
(2009)
J Clin Oncol
, vol.27
, Issue.15s
, pp. 5012
-
-
Chi, K.N.1
Hotte, S.J.2
Yu, E.3
Tu, D.4
Eigl, B.5
Tannock, I.6
-
35
-
-
40749122148
-
A phase II clinical trial of sorafenib in androgen-independent prostate cancer
-
Dahut, W.L., Scripture, C., Posadas, E., Jain, L., Gulley, J.L., Arlen, P.M. et al. (2008) A phase II clinical trial of sorafenib in androgen-independent prostate cancer. Clin Cancer Res 14: 209-214.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 209-214
-
-
Dahut, W.L.1
Scripture, C.2
Posadas, E.3
Jain, L.4
Gulley, J.L.5
Arlen, P.M.6
-
36
-
-
33846927744
-
(2007) Open-label phase II study evaluating the efficacy and safety of two doses of pertuzumab in castrate chemotherapy-naive patients with hormone-refractory prostate cancer
-
de Bono, J.S., Bellmunt, J., Attard, G., Droz, J.P., Miller, K., Flechon, A. et al. (2007) Open-label phase II study evaluating the efficacy and safety of two doses of pertuzumab in castrate chemotherapy-naive patients with hormone-refractory prostate cancer. J Clin Oncol 25: 257-262.
-
J Clin Oncol
, vol.25
, pp. 257-262
-
-
de Bono, J.S.1
Bellmunt, J.2
Attard, G.3
Droz, J.P.4
Miller, K.5
Flechon, A.6
-
37
-
-
62749096589
-
(2009) Mammalian target of rapamycin complex 1: signalling inputs, substrates and feedback mechanisms
-
Dunlop, E.A. and Tee, A.R. (2009) Mammalian target of rapamycin complex 1: signalling inputs, substrates and feedback mechanisms. Cell Signal 21: 827-835.
-
Cell Signal
, vol.21
, pp. 827-835
-
-
Dunlop, E.A.1
Tee, A.R.2
-
38
-
-
64849101452
-
(2009) Mammalian target of rapamycin complex 1-mediated phosphorylation of eukaryotic initiation factor 4E-binding protein 1 requires multiple protein-protein interactions for substrate recognition
-
Dunlop, E.A., Dodd, K.M., Seymour, L.A. and Tee, A.R. (2009) Mammalian target of rapamycin complex 1-mediated phosphorylation of eukaryotic initiation factor 4E-binding protein 1 requires multiple protein-protein interactions for substrate recognition. Cell Signal 21: 1073-1084.
-
Cell Signal
, vol.21
, pp. 1073-1084
-
-
Dunlop, E.A.1
Dodd, K.M.2
Seymour, L.A.3
Tee, A.R.4
-
39
-
-
34748840882
-
Effect of the histone deacetylase inhibitor LBH 589 against epidermal growth factor receptor-dependent human lung cancer cells
-
Edwards, A., Li, J., Atadja, P., Bhalla, K. and Haura, E.B. ( 2007) Effect of the histone deacetylase inhibitor LBH 589 against epidermal growth factor receptor-dependent human lung cancer cells. Mol Cancer Ther 6: 2515-2524.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 2515-2524
-
-
Edwards, A.1
Li, J.2
Atadja, P.3
Bhalla, K.4
Haura, E.B.5
-
40
-
-
77955607404
-
Integrated quantative and spatial proteomic analysis of PI3kinase signaling in high grade prostate cancer (PCa) treated with temsirolimus with or without androgen ablation
-
Efstathiou, E., Tsavachidou, D., Wen, S., Troncoso, P., Mills, G.B. and Logothetis, C.J. ( 2008) Integrated quantative and spatial proteomic analysis of PI3kinase signaling in high grade prostate cancer (PCa) treated with temsirolimus with or without androgen ablation. J Clin Oncol (Meeting Abstracts) 26: 5071.
-
(2008)
J Clin Oncol (Meeting Abstracts)
, vol.26
, pp. 5071
-
-
Efstathiou, E.1
Tsavachidou, D.2
Wen, S.3
Troncoso, P.4
Mills, G.B.5
Logothetis, C.J.6
-
41
-
-
54449084015
-
Randomized trial of denosumab in patients receiving adjuvant aromatase inhibitors for nonmetastatic breast cancer
-
Ellis, G.K., Bone, H.G., Chlebowski, R., Paul, D., Spadafora, S., Smith, J. et al. (2008) Randomized trial of denosumab in patients receiving adjuvant aromatase inhibitors for nonmetastatic breast cancer. J Clin Oncol 26: 4875-4882.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4875-4882
-
-
Ellis, G.K.1
Bone, H.G.2
Chlebowski, R.3
Paul, D.4
Spadafora, S.5
Smith, J.6
-
42
-
-
70249097380
-
(2009) Sorafenib for treatment of renal cell carcinoma: Final efficacy and safety results of the phase III treatment approaches in renal cancer global evaluation trial
-
Escudier, B., Eisen, T., Stadler, W.M., Szczylik, C., Oudard, S., Staehler, M. et al. (2009) Sorafenib for treatment of renal cell carcinoma: Final efficacy and safety results of the phase III treatment approaches in renal cancer global evaluation trial. J Clin Oncol 27: 3312-3318.
-
J Clin Oncol
, vol.27
, pp. 3312-3318
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
Szczylik, C.4
Oudard, S.5
Staehler, M.6
-
43
-
-
0035496220
-
The development of androgen-independent prostate cancer
-
Feldman, B.J. and Feldman, D. ( 2001) The development of androgen-independent prostate cancer. Nat Rev Cancer 1: 34-45.
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 34-45
-
-
Feldman, B.J.1
Feldman, D.2
-
44
-
-
0034783270
-
A randomized phase II trial of thalidomide, an angiogenesis inhibitor, in patients with androgen-independent prostate cancer
-
Figg, W.D., Dahut, W., Duray, P., Hamilton, M., Tompkins, A., Steinberg, S.M. et al. (2001) A randomized phase II trial of thalidomide, an angiogenesis inhibitor, in patients with androgen-independent prostate cancer. Clin Cancer Res 7: 1888-1893.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1888-1893
-
-
Figg, W.D.1
Dahut, W.2
Duray, P.3
Hamilton, M.4
Tompkins, A.5
Steinberg, S.M.6
-
45
-
-
0036282502
-
Inhibition of angiogenesis: treatment options for patients with metastatic prostate cancer
-
Figg, W.D., Kruger, E.A., Price, D.K., Kim, S. and Dahut, W.D. ( 2002) Inhibition of angiogenesis: treatment options for patients with metastatic prostate cancer. Invest New Drugs 20: 183-194.
-
(2002)
Invest New Drugs
, vol.20
, pp. 183-194
-
-
Figg, W.D.1
Kruger, E.A.2
Price, D.K.3
Kim, S.4
Dahut, W.D.5
-
46
-
-
36248973171
-
The role of Src in prostate cancer
-
Fizazi, K. ( 2007) The role of Src in prostate cancer. Ann Oncol 18: 1765-1773.
-
(2007)
Ann Oncol
, vol.18
, pp. 1765-1773
-
-
Fizazi, K.1
-
47
-
-
66349089867
-
(2009) Phase II trial of consolidation docetaxel and samarium-153 in patients with bone metastases from castration-resistant prostate cancer
-
Fizazi, K., Beuzeboc, P., Lumbroso, J., Haddad, V., Massard, C., Gross-Goupil, M. et al. (2009) Phase II trial of consolidation docetaxel and samarium-153 in patients with bone metastases from castration-resistant prostate cancer. J Clin Oncol 27: 2429-2435.
-
J Clin Oncol
, vol.27
, pp. 2429-2435
-
-
Fizazi, K.1
Beuzeboc, P.2
Lumbroso, J.3
Haddad, V.4
Massard, C.5
Gross-Goupil, M.6
-
48
-
-
55949083407
-
Anti-cytotoxic T-lymphocyte antigen-4 antibody: the first in an emerging class of immunomodulatory antibodies for cancer treatment
-
Fong, L. and Small, E.J. ( 2008) Anti-cytotoxic T-lymphocyte antigen-4 antibody: the first in an emerging class of immunomodulatory antibodies for cancer treatment. J Clin Oncol 26: 5275-5283.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5275-5283
-
-
Fong, L.1
Small, E.J.2
-
49
-
-
49849098119
-
Mammalian target of rapamycin inhibition as a therapeutic strategy in the management of urologic malignancies
-
Garcia, J.A. and Danielpour, D. ( 2008) Mammalian target of rapamycin inhibition as a therapeutic strategy in the management of urologic malignancies. Mol Cancer Ther 7: 1347-1354.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 1347-1354
-
-
Garcia, J.A.1
Danielpour, D.2
-
50
-
-
0034772250
-
Prognostic significance of plasma vascular endothelial growth factor levels in patients with hormone-refractory prostate cancer treated on Cancer and Leukemia Group B 9480
-
George, D.J., Halabi, S., Shepard, T.F., Vogelzang, N.J., Hayes, D.F., Small, E.J. et al. (2001) Prognostic significance of plasma vascular endothelial growth factor levels in patients with hormone-refractory prostate cancer treated on Cancer and Leukemia Group B 9480. Clin Cancer Res 7: 1932-1936.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1932-1936
-
-
George, D.J.1
Halabi, S.2
Shepard, T.F.3
Vogelzang, N.J.4
Hayes, D.F.5
Small, E.J.6
-
51
-
-
84993757629
-
A phase II study of RAD 001 in men with hormone-refractory metastatic prostate cancer
-
Proceedings of the Genitourinary Cancers Symposium Abstract 181.
-
George, D.A., Armstrong, A.J., Creel, P., Morris, K., Madden, J., Turnbull, J. et al. (2008) A phase II study of RAD 001 in men with hormone-refractory metastatic prostate cancer. Proceedings of the Genitourinary Cancers Symposium, Abstract 181.
-
(2008)
-
-
George, D.A.1
Armstrong, A.J.2
Creel, P.3
Morris, K.4
Madden, J.5
Turnbull, J.6
-
52
-
-
0032785072
-
Targeting bcl-2 gene to delay androgen-independent progression and enhance chemosensitivity in prostate cancer using antisense bcl-2 oligodeoxynucleotides
-
Gleave, M.E., Miayake, H., Goldie, J., Nelson, C. and Tolcher, A. ( 1999) Targeting bcl-2 gene to delay androgen-independent progression and enhance chemosensitivity in prostate cancer using antisense bcl-2 oligodeoxynucleotides. Urology 54: 36-46.
-
(1999)
Urology
, vol.54
, pp. 36-46
-
-
Gleave, M.E.1
Miayake, H.2
Goldie, J.3
Nelson, C.4
Tolcher, A.5
-
53
-
-
0036060493
-
State-of-the-art treatment of metastatic hormone-refractory prostate cancer
-
Goodin, S., Rao, K.V. and DiPaola, R.S. ( 2002) State-of-the-art treatment of metastatic hormone-refractory prostate cancer. Oncologist 7: 360-370.
-
(2002)
Oncologist
, vol.7
, pp. 360-370
-
-
Goodin, S.1
Rao, K.V.2
DiPaola, R.S.3
-
54
-
-
0034637524
-
Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression
-
Graff, J.R., Konicek, B.W., McNulty, A.M., Wang, Z., Houck, K., Allen, S. et al. (2000) Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression. J Biol Chem 275: 24500-24505.
-
(2000)
J Biol Chem
, vol.275
, pp. 24500-24505
-
-
Graff, J.R.1
Konicek, B.W.2
McNulty, A.M.3
Wang, Z.4
Houck, K.5
Allen, S.6
-
55
-
-
16344363218
-
Heregulin-induced activation of HER 2 and HER 3 increases androgen receptor transactivation and CWR-R1 human recurrent prostate cancer cell growth
-
Gregory, C.W., Whang, Y.E., McCall, W., Fei, X., Liu, Y., Ponguta, L.A. et al. (2005) Heregulin-induced activation of HER 2 and HER 3 increases androgen receptor transactivation and CWR-R1 human recurrent prostate cancer cell growth. Clin Cancer Res 11: 1704-1712.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 1704-1712
-
-
Gregory, C.W.1
Whang, Y.E.2
McCall, W.3
Fei, X.4
Liu, Y.5
Ponguta, L.A.6
-
56
-
-
0036830256
-
Inhibitors of mTOR reverse doxorubicin resistance conferred by PTEN status in prostate cancer cells
-
Grunwald, V., de Graffenried, L., Russel, D., Friedrichs, W.E., Ray, R.B. and Hidalgo, M. ( 2002) Inhibitors of mTOR reverse doxorubicin resistance conferred by PTEN status in prostate cancer cells. Cancer Res 62: 6141-6145.
-
(2002)
Cancer Res
, vol.62
, pp. 6141-6145
-
-
Grunwald, V.1
de Graffenried, L.2
Russel, D.3
Friedrichs, W.E.4
Ray, R.B.5
Hidalgo, M.6
-
57
-
-
34548438462
-
Therapeutic options for hormone-refractory prostate cancer in 2007
-
Hadaschik, B.A. and Gleave, M.E. ( 2007) Therapeutic options for hormone-refractory prostate cancer in 2007. Urol Oncol 25: 413-419.
-
(2007)
Urol Oncol
, vol.25
, pp. 413-419
-
-
Hadaschik, B.A.1
Gleave, M.E.2
-
58
-
-
50349085911
-
Effect of SLCO1B3 haplotype on testosterone transport and clinical outcome in caucasian patients with androgen-independent prostatic cancer
-
Hamada, A., Sissung, T., Price, D.K., Danesi, R., Chau, C.H., Sharifi, N. et al. (2008) Effect of SLCO1B3 haplotype on testosterone transport and clinical outcome in caucasian patients with androgen-independent prostatic cancer. Clin Cancer Res 14: 3312-3318.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3312-3318
-
-
Hamada, A.1
Sissung, T.2
Price, D.K.3
Danesi, R.4
Chau, C.H.5
Sharifi, N.6
-
59
-
-
66249109921
-
(2009) Immunotherapeutics in development for prostate cancer
-
Harzstark, A.L. and Small, E.J. (2009) Immunotherapeutics in development for prostate cancer. Oncologist 14: 391-398.
-
Oncologist
, vol.14
, pp. 391-398
-
-
Harzstark, A.L.1
Small, E.J.2
-
60
-
-
61549140178
-
A phase II trial of 17-allylamino-17-demethoxygeldanamycin (17-AAG) in patients with hormone-refractory metastatic prostate cancer
-
Heath, E.I., Hillman, D., Vaishampayan, U., Sheng, S., Sarkar, F.H., Gaskins, M. et al. (2007) A phase II trial of 17-allylamino-17-demethoxygeldanamycin (17-AAG) in patients with hormone-refractory metastatic prostate cancer. J Clin Oncol (Meeting Abstracts) 25: 15553.
-
(2007)
J Clin Oncol (Meeting Abstracts)
, vol.25
, pp. 15553
-
-
Heath, E.I.1
Hillman, D.2
Vaishampayan, U.3
Sheng, S.4
Sarkar, F.H.5
Gaskins, M.6
-
61
-
-
52049090425
-
Phase 1 / 2 dose-escalation study of a GM-CSF-secreting, allogeneic, cellular immunotherapy for metastatic hormone-refractory prostate cancer
-
Higano, C.S., Corman, J.M., Smith, D.C., Centeno, A.S., Steidle, C.P., Gittleman, M. et al. (2008) Phase 1 / 2 dose-escalation study of a GM-CSF-secreting, allogeneic, cellular immunotherapy for metastatic hormone-refractory prostate cancer. Cancer 113: 975-984.
-
(2008)
Cancer
, vol.113
, pp. 975-984
-
-
Higano, C.S.1
Corman, J.M.2
Smith, D.C.3
Centeno, A.S.4
Steidle, C.P.5
Gittleman, M.6
-
62
-
-
71249156207
-
A phase III trial of GVAX immunotherapy for prostate cancer versus docetaxel plus prednisone in asymptomatic, castration-resistant prostate cancer (CRPC)
-
Genitourinary Cancers Symposium Abstract LBA150.
-
Higano, C., Saad, F., Somer, B., Curti, B., Petrylak, D., Drake, C.G. et al. (2009) A phase III trial of GVAX immunotherapy for prostate cancer versus docetaxel plus prednisone in asymptomatic, castration-resistant prostate cancer (CRPC). Genitourinary Cancers Symposium, Abstract LBA150.
-
(2009)
-
-
Higano, C.1
Saad, F.2
Somer, B.3
Curti, B.4
Petrylak, D.5
Drake, C.G.6
-
63
-
-
3242781731
-
Clinical implications of the osteoprotegerin/RANKL/RANK system for bone and vascular diseases
-
Hofbauer, L.C. and Schoppet, M. ( 2004) Clinical implications of the osteoprotegerin/RANKL/RANK system for bone and vascular diseases. JAMA 292: 490-495.
-
(2004)
JAMA
, vol.292
, pp. 490-495
-
-
Hofbauer, L.C.1
Schoppet, M.2
-
64
-
-
34748912386
-
Androgen-response elements in hormone-refractory prostate cancer: implications for treatment development
-
Hsieh, A.C., Small, E.J. and Ryan, C.J. ( 2007) Androgen-response elements in hormone-refractory prostate cancer: implications for treatment development. Lancet Oncol 8: 933-939.
-
(2007)
Lancet Oncol
, vol.8
, pp. 933-939
-
-
Hsieh, A.C.1
Small, E.J.2
Ryan, C.J.3
-
65
-
-
0033548566
-
Clusterin has chaperone-like activity similar to that of small heat shock proteins
-
Humphreys, D.T., Carver, J.A., Easterbrook-Smith, S.B. and Wilson, M.R. ( 1999) Clusterin has chaperone-like activity similar to that of small heat shock proteins. J Biol Chem 274: 6875-6881.
-
(1999)
J Biol Chem
, vol.274
, pp. 6875-6881
-
-
Humphreys, D.T.1
Carver, J.A.2
Easterbrook-Smith, S.B.3
Wilson, M.R.4
-
66
-
-
33644843604
-
Ixabepilone (epothilone B analogue BMS-247550) is active in chemotherapy-naive patients with hormone-refractory prostate cancer: a Southwest Oncology Group trial S0111
-
Hussain, M., Tangen, C.M., Lara Jr, P.N., Vaishampayan, U.N., Petrylak, D.P., Colevas, A.D. et al. (2005) Ixabepilone (epothilone B analogue BMS-247550) is active in chemotherapy-naive patients with hormone-refractory prostate cancer: a Southwest Oncology Group trial S0111. J Clin Oncol 23: 8724-8729.
-
(2005)
J Clin Oncol
, vol.23
, pp. 8724-8729
-
-
Hussain, M.1
Tangen, C.M.2
Lara Jr, P.N.3
Vaishampayan, U.N.4
Petrylak, D.P.5
Colevas, A.D.6
-
67
-
-
34047260282
-
Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: insights from a mathematical model
-
Jain, R.K., Tong, R.T. and Munn, L.L. ( 2007) Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: insights from a mathematical model. Cancer Res 67: 2729-2735.
-
(2007)
Cancer Res
, vol.67
, pp. 2729-2735
-
-
Jain, R.K.1
Tong, R.T.2
Munn, L.L.3
-
68
-
-
62649134676
-
Safety and efficacy of the specific endothelin-A receptor antagonist ZD 4054 in patients with hormone-resistant prostate cancer and bone metastases who were pain free or mildly symptomatic: a double-blind, placebo-controlled, randomised, phase 2 trial
-
James, N.D., Caty, A., Borre, M., Zonnenberg, B.A., Beuzeboc, P., Morris, T. et al. (2008) Safety and efficacy of the specific endothelin-A receptor antagonist ZD 4054 in patients with hormone-resistant prostate cancer and bone metastases who were pain free or mildly symptomatic: a double-blind, placebo-controlled, randomised, phase 2 trial. Eur Urol 55: 1112-1123.
-
(2008)
Eur Urol
, vol.55
, pp. 1112-1123
-
-
James, N.D.1
Caty, A.2
Borre, M.3
Zonnenberg, B.A.4
Beuzeboc, P.5
Morris, T.6
-
69
-
-
67649814136
-
(2009) PI3K/PTEN signaling in angiogenesis and tumorigenesis
-
Jiang, B.H. and Liu, L.Z. (2009) PI3K/PTEN signaling in angiogenesis and tumorigenesis. Adv Cancer Res 102: 19-65.
-
Adv Cancer Res
, vol.102
, pp. 19-65
-
-
Jiang, B.H.1
Liu, L.Z.2
-
70
-
-
0037083472
-
Clusterin expression is significantly enhanced in prostate cancer cells following androgen withdrawal therapy
-
July, L.V., Akbari, M., Zellweger, T., Jones, E.C., Goldenberg, S.L. and Gleave, M.E. ( 2002) Clusterin expression is significantly enhanced in prostate cancer cells following androgen withdrawal therapy. Prostate 50: 179-188.
-
(2002)
Prostate
, vol.50
, pp. 179-188
-
-
July, L.V.1
Akbari, M.2
Zellweger, T.3
Jones, E.C.4
Goldenberg, S.L.5
Gleave, M.E.6
-
71
-
-
50949097756
-
Evolving perspectives of the role of novel agents in androgen-independent prostate cancer
-
Kalmadi, S. and Raghavan, D. ( 2008) Evolving perspectives of the role of novel agents in androgen-independent prostate cancer. Indian J Urol 24: 303-308.
-
(2008)
Indian J Urol
, vol.24
, pp. 303-308
-
-
Kalmadi, S.1
Raghavan, D.2
-
72
-
-
69349087945
-
Overall survival (OS) analysis of a phase II randomized controlled trial (RCT) of a poxviral-based PSA targeted immunotherapy in metastatic castration resistant prostate cancer (mCRPC)
-
(Suppl): abstract
-
Kantoff, P.W. ( 2009) Overall survival (OS) analysis of a phase II randomized controlled trial (RCT) of a poxviral-based PSA targeted immunotherapy in metastatic castration resistant prostate cancer (mCRPC). J Clin Oncol 27(Suppl): abstract 5013.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5013
-
-
Kantoff, P.W.1
-
73
-
-
0038756444
-
Castration-induced increases in insulin-like growth factor-binding protein 2 promotes proliferation of androgen-independent human prostate LNCaP tumors
-
Kiyama, S., Morrison, K., Zellweger, T., Akbari, M., Cox, M., Yu, D. et al. (2003) Castration-induced increases in insulin-like growth factor-binding protein 2 promotes proliferation of androgen-independent human prostate LNCaP tumors. Cancer Res 63: 3575-3584.
-
(2003)
Cancer Res
, vol.63
, pp. 3575-3584
-
-
Kiyama, S.1
Morrison, K.2
Zellweger, T.3
Akbari, M.4
Cox, M.5
Yu, D.6
-
74
-
-
3042851917
-
Combination of somatostatin analog, dexamethasone, and standard androgen ablation therapy in stage D 3 prostate cancer patients with bone metastases
-
Koutsilieris, M., Mitsiades, C.S., Bogdanos, J., Dimopoulos, T., Karamanolakis, D., Milathianakis, C. et al. (2004) Combination of somatostatin analog, dexamethasone, and standard androgen ablation therapy in stage D 3 prostate cancer patients with bone metastases. Clin Cancer Res 10: 4398-4405.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 4398-4405
-
-
Koutsilieris, M.1
Mitsiades, C.S.2
Bogdanos, J.3
Dimopoulos, T.4
Karamanolakis, D.5
Milathianakis, C.6
-
75
-
-
3442891477
-
Phosphorylation of Akt (Ser473) is an excellent predictor of poor clinical outcome in prostate cancer
-
Kreisberg, J.I., Malik, S.N., Prihoda, T.J., Bedolla, R.G., Troyer, D.A., Kreisberg, S. et al. (2004) Phosphorylation of Akt (Ser473) is an excellent predictor of poor clinical outcome in prostate cancer. Cancer Res 64: 5232-5236.
-
(2004)
Cancer Res
, vol.64
, pp. 5232-5236
-
-
Kreisberg, J.I.1
Malik, S.N.2
Prihoda, T.J.3
Bedolla, R.G.4
Troyer, D.A.5
Kreisberg, S.6
-
76
-
-
9244242088
-
Increased insulin-like growth factor I receptor expression and signaling are components of androgen-independent progression in a lineage-derived prostate cancer progression model
-
Krueckl, S.L., Sikes, R.A., Edlund, N.M., Bell, R.H., Hurtado-Coll, A., Fazli, L. et al. (2004) Increased insulin-like growth factor I receptor expression and signaling are components of androgen-independent progression in a lineage-derived prostate cancer progression model. Cancer Res 64: 8620-8629.
-
(2004)
Cancer Res
, vol.64
, pp. 8620-8629
-
-
Krueckl, S.L.1
Sikes, R.A.2
Edlund, N.M.3
Bell, R.H.4
Hurtado-Coll, A.5
Fazli, L.6
-
77
-
-
67650376190
-
(2009) Emerging therapies in castrate-resistant prostate cancer
-
Lassi, K. and Dawson, N.A. (2009) Emerging therapies in castrate-resistant prostate cancer. Curr Opin Oncol 21: 260-265.
-
Curr Opin Oncol
, vol.21
, pp. 260-265
-
-
Lassi, K.1
Dawson, N.A.2
-
78
-
-
0142126160
-
Differentiating agents and the treatment of prostate cancer: Vitamin D 3 and peroxisome proliferator-activated receptor gamma ligands
-
Leibowitz, S.B. and Kantoff, P.W. ( 2003) Differentiating agents and the treatment of prostate cancer: Vitamin D 3 and peroxisome proliferator-activated receptor gamma ligands. Semin Oncol 30: 698-708.
-
(2003)
Semin Oncol
, vol.30
, pp. 698-708
-
-
Leibowitz, S.B.1
Kantoff, P.W.2
-
79
-
-
33646799364
-
Molecular pharmacodynamic (MPD) evaluation of dose and schedule of RAD 001 (everolimus) in patients with operable prostate carcinoma (PC)
-
Lerut, E., Roskams, T., Goossens, E., Bootle, D., Dimitrijevic, S., Stumm, M. et al. (2005) Molecular pharmacodynamic (MPD) evaluation of dose and schedule of RAD 001 (everolimus) in patients with operable prostate carcinoma (PC). J Clin Oncol (Meeting Abstracts) 23: 3071.
-
(2005)
J Clin Oncol (Meeting Abstracts)
, vol.23
, pp. 3071
-
-
Lerut, E.1
Roskams, T.2
Goossens, E.3
Bootle, D.4
Dimitrijevic, S.5
Stumm, M.6
-
80
-
-
20244387835
-
Evidence for the presence of disease-perturbed networks in prostate cancer cells by genomic and proteomic analyses: a systems approach to disease
-
Lin, B., White, J.T., Lu, W., Xie, T., Utleg, A.G., Yan, X. et al. (2005) Evidence for the presence of disease-perturbed networks in prostate cancer cells by genomic and proteomic analyses: a systems approach to disease. Cancer Res 65: 3081-3091.
-
(2005)
Cancer Res
, vol.65
, pp. 3081-3091
-
-
Lin, B.1
White, J.T.2
Lu, W.3
Xie, T.4
Utleg, A.G.5
Yan, X.6
-
81
-
-
27844506524
-
Akt-regulated pathways in prostate cancer
-
Majumder, P.K. and Sellers, W.R. ( 2005) Akt-regulated pathways in prostate cancer. Oncogene 24: 7465-7474.
-
(2005)
Oncogene
, vol.24
, pp. 7465-7474
-
-
Majumder, P.K.1
Sellers, W.R.2
-
82
-
-
2942724235
-
mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways
-
Majumder, P.K., Febbo, P.G., Bikoff, R., Berger, R., Xue, Q., McMahon, L.M. et al. (2004) mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways. Nat Med 10: 594-601.
-
(2004)
Nat Med
, vol.10
, pp. 594-601
-
-
Majumder, P.K.1
Febbo, P.G.2
Bikoff, R.3
Berger, R.4
Xue, Q.5
McMahon, L.M.6
-
83
-
-
0036554734
-
Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer
-
Malik, S.N., Brattain, M., Ghosh, P.M., Troyer, D.A., Prihoda, T., Bedolla, R. et al. (2002) Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer. Clin Cancer Res 8: 1168-1171.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1168-1171
-
-
Malik, S.N.1
Brattain, M.2
Ghosh, P.M.3
Troyer, D.A.4
Prihoda, T.5
Bedolla, R.6
-
84
-
-
33846839622
-
Suberoylanilide hydroxamic acid (vorinostat) represses androgen receptor expression and acts synergistically with an androgen receptor antagonist to inhibit prostate cancer cell proliferation
-
Marrocco, D.L., Tilley, W.D., Bianco-Miotto, T., Evdokiou, A., Scher, H.I., Rifkind, R.A. et al. (2007) Suberoylanilide hydroxamic acid (vorinostat) represses androgen receptor expression and acts synergistically with an androgen receptor antagonist to inhibit prostate cancer cell proliferation. Mol Cancer Ther 6: 51-60.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 51-60
-
-
Marrocco, D.L.1
Tilley, W.D.2
Bianco-Miotto, T.3
Evdokiou, A.4
Scher, H.I.5
Rifkind, R.A.6
-
85
-
-
0029009875
-
Phase I-II study of the somatostatin analogue lanreotide in hormone-refractory prostate cancer
-
Maulard, C., Richaud, P., Droz, J.P., Jessueld, D., Dufour-Esquerre, F. and Housset, M. ( 1995) Phase I-II study of the somatostatin analogue lanreotide in hormone-refractory prostate cancer. Cancer Chemother Pharmacol 36: 259-262.
-
(1995)
Cancer Chemother Pharmacol
, vol.36
, pp. 259-262
-
-
Maulard, C.1
Richaud, P.2
Droz, J.P.3
Jessueld, D.4
Dufour-Esquerre, F.5
Housset, M.6
-
86
-
-
0033200172
-
Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage
-
McMenamin, M.E., Soung, P., Perera, S., Kaplan, I., Loda, M. and Sellers, W.R. ( 1999) Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage. Cancer Res 59: 4291-4296.
-
(1999)
Cancer Res
, vol.59
, pp. 4291-4296
-
-
McMenamin, M.E.1
Soung, P.2
Perera, S.3
Kaplan, I.4
Loda, M.5
Sellers, W.R.6
-
87
-
-
0034112089
-
Antisense TRPM-2 oligodeoxynucleotides chemosensitize human androgen-independent PC-3 prostate cancer cells both in vitro and in vivo
-
Miyake, H., Chi, K.N. and Gleave, M.E. ( 2000a) Antisense TRPM-2 oligodeoxynucleotides chemosensitize human androgen-independent PC-3 prostate cancer cells both in vitro and in vivo. Clin Cancer Res 6: 1655-1663.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1655-1663
-
-
Miyake, H.1
Chi, K.N.2
Gleave, M.E.3
-
88
-
-
0033978525
-
Testosterone-repressed prostate message-2 is an antiapoptotic gene involved in progression to androgen independence in prostate cancer
-
Miyake, H., Nelson, C., Rennie, P.S. and Gleave, M.E. ( 2000b) Testosterone-repressed prostate message-2 is an antiapoptotic gene involved in progression to androgen independence in prostate cancer. Cancer Res 60: 170-176.
-
(2000)
Cancer Res
, vol.60
, pp. 170-176
-
-
Miyake, H.1
Nelson, C.2
Rennie, P.S.3
Gleave, M.E.4
-
89
-
-
0037083383
-
HER-2 profiling and targeting in prostate carcinoma
-
Morris, M.J., Reuter, V.E., Kelly, W.K., Slovin, S.F., Kenneson, K., Verbel, D. et al. (2002) HER-2 profiling and targeting in prostate carcinoma. Cancer 94: 980-986.
-
(2002)
Cancer
, vol.94
, pp. 980-986
-
-
Morris, M.J.1
Reuter, V.E.2
Kelly, W.K.3
Slovin, S.F.4
Kenneson, K.5
Verbel, D.6
-
90
-
-
66349100456
-
(2009) Phase I study of samarium-153 lexidronam with docetaxel in castration-resistant metastatic prostate cancer
-
Morris, M.J., Pandit-Taskar, N., Carrasquillo, J., Divgi, C.R., Slovin, S., Kelly, W.K. et al. (2009) Phase I study of samarium-153 lexidronam with docetaxel in castration-resistant metastatic prostate cancer. J Clin Oncol 27: 2436-2442.
-
J Clin Oncol
, vol.27
, pp. 2436-2442
-
-
Morris, M.J.1
Pandit-Taskar, N.2
Carrasquillo, J.3
Divgi, C.R.4
Slovin, S.5
Kelly, W.K.6
-
91
-
-
0034749615
-
Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state
-
Murillo, H., Huang, H., Schmidt, L.J., Smith, D.I. and Tindall, D.J. ( 2001) Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state. Endocrinology 142: 4795-4805.
-
(2001)
Endocrinology
, vol.142
, pp. 4795-4805
-
-
Murillo, H.1
Huang, H.2
Schmidt, L.J.3
Smith, D.I.4
Tindall, D.J.5
-
92
-
-
27144547509
-
Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells
-
Nam, S., Kim, D., Cheng, J.Q., Zhang, S., Lee, J.H., Buettner, R. et al. (2005) Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells. Cancer Res 65: 9185-9189.
-
(2005)
Cancer Res
, vol.65
, pp. 9185-9189
-
-
Nam, S.1
Kim, D.2
Cheng, J.Q.3
Zhang, S.4
Lee, J.H.5
Buettner, R.6
-
93
-
-
0029085123
-
Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate
-
Nelson, J.B., Hedican, S.P., George, D.J., Reddi, A.H., Piantadosi, S., Eisenberger, M.A. et al. (1995) Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate. Nat Med 1: 944-949.
-
(1995)
Nat Med
, vol.1
, pp. 944-949
-
-
Nelson, J.B.1
Hedican, S.P.2
George, D.J.3
Reddi, A.H.4
Piantadosi, S.5
Eisenberger, M.A.6
-
94
-
-
0030047858
-
Endothelin-1 production and decreased endothelin B receptor expression in advanced prostate cancer
-
Nelson, J.B., Chan-Tack, K., Hedican, S.P., Magnuson, S.R., Opgenorth, T.J., Bova, G.S. et al. (1996) Endothelin-1 production and decreased endothelin B receptor expression in advanced prostate cancer. Cancer Res 56: 663-668.
-
(1996)
Cancer Res
, vol.56
, pp. 663-668
-
-
Nelson, J.B.1
Chan-Tack, K.2
Hedican, S.P.3
Magnuson, S.R.4
Opgenorth, T.J.5
Bova, G.S.6
-
95
-
-
55549112219
-
Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone-refractory prostate cancer
-
Nelson, J.B., Love, W., Chin, J.L., Saad, F., Schulman, C.C., Sleep, D.J. et al. (2008) Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone-refractory prostate cancer. Cancer 113: 2478-2487.
-
(2008)
Cancer
, vol.113
, pp. 2478-2487
-
-
Nelson, J.B.1
Love, W.2
Chin, J.L.3
Saad, F.4
Schulman, C.C.5
Sleep, D.J.6
-
96
-
-
34247142405
-
A phase II trial of docetaxel thalidomide bevacizumab and prednisone in patients with metastatic androgen independent prostate cancer
-
abstract
-
Ning, Y.M., Arlen, P.M. and Gulley, J. ( 2006) A phase II trial of docetaxel thalidomide bevacizumab and prednisone in patients with metastatic androgen independent prostate cancer. Proc Am Soc Clin Oncol 24: abstract 13037.
-
(2006)
Proc Am Soc Clin Oncol
, vol.24
, pp. 13037
-
-
Ning, Y.M.1
Arlen, P.M.2
Gulley, J.3
-
97
-
-
26944438280
-
Early clinical data and potential clinical utility of novel histone deacetylase inhibitors in prostate cancer
-
No authors listed
-
No authors listed. (2005) Early clinical data and potential clinical utility of novel histone deacetylase inhibitors in prostate cancer. Clin Prostate Cancer 4: 83-85.
-
(2005)
Clin Prostate Cancer
, vol.4
, pp. 83-85
-
-
-
98
-
-
32944457518
-
mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt
-
O'Reilly, K.E., Rojo, F., She, Q.-B., Solit, D., Mills, G.B., Smith, D. et al. (2006) mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt. Cancer Res 66: 1500-1508.
-
(2006)
Cancer Res
, vol.66
, pp. 1500-1508
-
-
O'Reilly, K.E.1
Rojo, F.2
She, Q.-B.3
Solit, D.4
Mills, G.B.5
Smith, D.6
-
99
-
-
0036159186
-
Her-2/neu oncogene amplification in clinically localised prostate cancer
-
Oxley, J.D., Winkler, M.H., Gillatt, D.A. and Peat, D.S. ( 2002) Her-2/neu oncogene amplification in clinically localised prostate cancer. J Clin Pathol 55: 118-120.
-
(2002)
J Clin Pathol
, vol.55
, pp. 118-120
-
-
Oxley, J.D.1
Winkler, M.H.2
Gillatt, D.A.3
Peat, D.S.4
-
100
-
-
63749131928
-
Sunitinib maleate for metastatic castration resistant prostate cancer following docetaxel-based chemotherapy
-
abstract
-
Periman, P.O., Sonpavde, G. and Bernold, D.M. ( 2008) Sunitinib maleate for metastatic castration resistant prostate cancer following docetaxel-based chemotherapy. J Clin Oncol 26: abstract 5157.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5157
-
-
Periman, P.O.1
Sonpavde, G.2
Bernold, D.M.3
-
101
-
-
4744337716
-
Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer
-
Petrylak, D.P., Tangen, C.M., Hussain, M.H., Lara Jr, P.N., Jones, J.A., Taplin, M.E. et al. (2004) Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. N Engl J Med 351: 1513-1520.
-
(2004)
N Engl J Med
, vol.351
, pp. 1513-1520
-
-
Petrylak, D.P.1
Tangen, C.M.2
Hussain, M.H.3
Lara Jr, P.N.4
Jones, J.A.5
Taplin, M.E.6
-
102
-
-
0346880557
-
The use of bevacizumab (B) with docetaxel (D) and estramustine (E) in hormone refractory prostate cancer (HRPC): initial results of CALGB 90006
-
(abstr 1578).
-
Picus, J., Halabi, S., Rini, B., Vogelzang, N., Whang, Y., Kaplan, E. et al. (2003) The use of bevacizumab (B) with docetaxel (D) and estramustine (E) in hormone refractory prostate cancer (HRPC): initial results of CALGB 90006. Proc Am Soc Clin Oncol 22: (abstr 1578).
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
-
-
Picus, J.1
Halabi, S.2
Rini, B.3
Vogelzang, N.4
Whang, Y.5
Kaplan, E.6
-
103
-
-
75249097397
-
A multicenter phase II study of abiraterone acetate (AA) in docetaxel pretreated castration-resistant prostate cancer (CRPC) patients (pts)
-
abstr
-
Reid, A.H., Attard, G., Danila, D., Ryan, C.J., Thompson, E., Kheoh, T. et al. (2009) A multicenter phase II study of abiraterone acetate (AA) in docetaxel pretreated castration-resistant prostate cancer (CRPC) patients (pts). J Clin Oncol 27(15s): abstr 5047.
-
(2009)
J Clin Oncol
, vol.27
, Issue.15s
, pp. 5047
-
-
Reid, A.H.1
Attard, G.2
Danila, D.3
Ryan, C.J.4
Thompson, E.5
Kheoh, T.6
-
104
-
-
33645125545
-
Mechanisms of cell death induced by histone deacetylase inhibitors in androgen receptor-positive prostate cancer cells
-
Rokhlin, O.W., Glover, R.B., Guseva, N.V., Taghiyev, A.F., Kohlgraf, K.G. and Cohen, M.B. ( 2006) Mechanisms of cell death induced by histone deacetylase inhibitors in androgen receptor-positive prostate cancer cells. Mol Cancer Res 4: 113-123.
-
(2006)
Mol Cancer Res
, vol.4
, pp. 113-123
-
-
Rokhlin, O.W.1
Glover, R.B.2
Guseva, N.V.3
Taghiyev, A.F.4
Kohlgraf, K.G.5
Cohen, M.B.6
-
105
-
-
34547119271
-
Activity of second-line chemotherapy in docetaxel-refractory hormone-refractory prostate cancer patients: randomized phase 2 study of ixabepilone or mitoxantrone and prednisone
-
Rosenberg, J.E., Weinberg, V.K., Kelly, W.K., Michaelson, D., Hussain, M.H., Wilding, G. et al. (2007) Activity of second-line chemotherapy in docetaxel-refractory hormone-refractory prostate cancer patients: randomized phase 2 study of ixabepilone or mitoxantrone and prednisone. Cancer 110: 556-563.
-
(2007)
Cancer
, vol.110
, pp. 556-563
-
-
Rosenberg, J.E.1
Weinberg, V.K.2
Kelly, W.K.3
Michaelson, D.4
Hussain, M.H.5
Wilding, G.6
-
106
-
-
67649974684
-
(2009) Phase I study of ixabepilone, mitoxantrone, and prednisone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel-based therapy: a study of the department of defense prostate cancer clinical trials consortium
-
Rosenberg, J.E., Ryan, C.J., Weinberg, V.K., Smith, D.C., Hussain, M., Beer, T.M. et al. (2009) Phase I study of ixabepilone, mitoxantrone, and prednisone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel-based therapy: a study of the department of defense prostate cancer clinical trials consortium. J Clin Oncol 27: 2772-2778.
-
J Clin Oncol
, vol.27
, pp. 2772-2778
-
-
Rosenberg, J.E.1
Ryan, C.J.2
Weinberg, V.K.3
Smith, D.C.4
Hussain, M.5
Beer, T.M.6
-
107
-
-
39749137117
-
Inherited variation in the androgen pathway is associated with the efficacy of androgen-deprivation therapy in men with prostate cancer
-
Ross, R.W., Oh, W.K., Xie, W., Pomerantz, M., Nakabayashi, M., Sartor, O. et al. (2008 a) Inherited variation in the androgen pathway is associated with the efficacy of androgen-deprivation therapy in men with prostate cancer. J Clin Oncol 26: 842-847.
-
(2008)
J Clin Oncol
, vol.26
, pp. 842-847
-
-
Ross, R.W.1
Oh, W.K.2
Xie, W.3
Pomerantz, M.4
Nakabayashi, M.5
Sartor, O.6
-
108
-
-
67349247607
-
Phase I trial of RAD 001 (R) and docetaxel (D) in castration resistant prostate cancer (CRPC) with FDG-PET assessment of RAD 001 activity
-
Ross, R.W., Manola, J., Oh, W.K., Ryan, C., Kim, J., Rastarhuyeva, I. et al. (2008 b) Phase I trial of RAD 001 (R) and docetaxel (D) in castration resistant prostate cancer (CRPC) with FDG-PET assessment of RAD 001 activity. J Clin Oncol (Meeting Abstracts) 26: 5069.
-
(2008)
J Clin Oncol (Meeting Abstracts)
, vol.26
, pp. 5069
-
-
Ross, R.W.1
Manola, J.2
Oh, W.K.3
Ryan, C.4
Kim, J.5
Rastarhuyeva, I.6
-
109
-
-
34848903049
-
IMC-A12, a human IgG 1 monoclonal antibody to the insulin-like growth factor I receptor
-
Rowinsky, E.K., Youssoufian, H., Tonra, J.R., Solomon, P., Burtrum, D. and Ludwig, D.L. ( 2007) IMC-A12, a human IgG 1 monoclonal antibody to the insulin-like growth factor I receptor. Clin Cancer Res 13: 5549-5555.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 5549-5555
-
-
Rowinsky, E.K.1
Youssoufian, H.2
Tonra, J.R.3
Solomon, P.4
Burtrum, D.5
Ludwig, D.L.6
-
110
-
-
38549094538
-
A pilot dose-escalation study of the effects of nordihydroguareacetic acid on hormone and prostate specific antigen levels in patients with relapsed prostate cancer
-
Ryan, C.J., Harzstark, A.H., Rosenberg, J., Lin, A., Claros, C., Goldfine, I.D. et al. (2008) A pilot dose-escalation study of the effects of nordihydroguareacetic acid on hormone and prostate specific antigen levels in patients with relapsed prostate cancer. BJU Int 101: 436-439.
-
(2008)
BJU Int
, vol.101
, pp. 436-439
-
-
Ryan, C.J.1
Harzstark, A.H.2
Rosenberg, J.3
Lin, A.4
Claros, C.5
Goldfine, I.D.6
-
111
-
-
70349740108
-
Phase II multicenter study of chemotherapy (chemo)-naive castration-resistant prostate cancer (CRPC) not exposed to ketoconazole (keto), treated with abiraterone acetate (AA) plus prednisone
-
abstr
-
Ryan, C., Efstathiou, E., Smith, M., Taplin, M., Bubley, G., Logothetis, C. et al. (2009) Phase II multicenter study of chemotherapy (chemo)-naive castration-resistant prostate cancer (CRPC) not exposed to ketoconazole (keto), treated with abiraterone acetate (AA) plus prednisone. J Clin Oncol 27(15s): abstr 5046.
-
(2009)
J Clin Oncol
, vol.27
, Issue.15s
, pp. 5046
-
-
Ryan, C.1
Efstathiou, E.2
Smith, M.3
Taplin, M.4
Bubley, G.5
Logothetis, C.6
-
112
-
-
59249097068
-
Src as a therapeutic target in men with prostate cancer and bone metastases
-
Saad, F. ( 2009) Src as a therapeutic target in men with prostate cancer and bone metastases. BJU Int 103: 434-440.
-
(2009)
BJU Int
, vol.103
, pp. 434-440
-
-
Saad, F.1
-
113
-
-
59949097645
-
A phase II randomized study of custirsen (OGX-011) combination therapy in patients with poor-risk hormone refractory cancer (HRPC) who relapsed on or within six months of 1st-line docetaxel therapy
-
(suppl): abstract
-
Saad, F., Hotte, S.J. and North, S.A. ( 2008) A phase II randomized study of custirsen (OGX-011) combination therapy in patients with poor-risk hormone refractory cancer (HRPC) who relapsed on or within six months of 1st-line docetaxel therapy. J Clin Oncol 26(suppl): abstract 5002.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5002
-
-
Saad, F.1
Hotte, S.J.2
North, S.A.3
-
114
-
-
70349741668
-
Antitumor activity of MDV 3100 in a phase I / II study of castration-resistant prostate cancer (CRPC)
-
abstr
-
Scher, H.I. and Beer, T.M. ( 2009) Antitumor activity of MDV 3100 in a phase I / II study of castration-resistant prostate cancer (CRPC). J Clin Oncol 27: 15s; abstr 5011.
-
(2009)
J Clin Oncol
, vol.27
, Issue.15s
, pp. 5011
-
-
Scher, H.I.1
Beer, T.M.2
-
115
-
-
41949104346
-
Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group
-
Scher, H.I., Halabi, S., Tannock, I., Morris, M., Sternberg, C.N., Carducci, M.A. et al. (2008) Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group. J Clin Oncol 26: 1148-1159.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1148-1159
-
-
Scher, H.I.1
Halabi, S.2
Tannock, I.3
Morris, M.4
Sternberg, C.N.5
Carducci, M.A.6
-
116
-
-
51049092294
-
The genetics of castration-resistant prostate cancer: what can the germline tell us
-
Sharifi, N., Dahut, W.L. and Figg, W.D. ( 2008) The genetics of castration-resistant prostate cancer: what can the germline tell us? Clin Cancer Res 14: 4691-4693.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4691-4693
-
-
Sharifi, N.1
Dahut, W.L.2
Figg, W.D.3
-
117
-
-
0034614108
-
Her-2-neu expression and progression toward androgen independence in human prostate cancer
-
Signoretti, S., Montironi, R., Manola, J., Altimari, A., Tam, C., Bubley, G. et al. (2000) Her-2-neu expression and progression toward androgen independence in human prostate cancer. J Natl Cancer Inst 92: 1918-1925.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1918-1925
-
-
Signoretti, S.1
Montironi, R.2
Manola, J.3
Altimari, A.4
Tam, C.5
Bubley, G.6
-
118
-
-
33748162994
-
Granulocyte-macrophage colony-stimulating factor-transduced allogeneic cancer cellular immunotherapy: the GVAX vaccine for prostate cancer
-
Simons, J.W. and Sacks, N. ( 2006) Granulocyte-macrophage colony-stimulating factor-transduced allogeneic cancer cellular immunotherapy: the GVAX vaccine for prostate cancer. Urol Oncol 24: 419-424.
-
(2006)
Urol Oncol
, vol.24
, pp. 419-424
-
-
Simons, J.W.1
Sacks, N.2
-
119
-
-
0027243888
-
Vitamin D and prostate cancer: 1,25 dihydroxyvitamin D 3 receptors and actions in human prostate cancer cell lines
-
Skowronski, R.J., Peehl, D.M. and Feldman, D. ( 1993) Vitamin D and prostate cancer: 1,25 dihydroxyvitamin D 3 receptors and actions in human prostate cancer cell lines. Endocrinology 132: 1952-1960.
-
(1993)
Endocrinology
, vol.132
, pp. 1952-1960
-
-
Skowronski, R.J.1
Peehl, D.M.2
Feldman, D.3
-
120
-
-
77951443592
-
Initial phase II experience of ipilimumab (IPI) alone and in combination with radiotherapy (XRT) in patients with metastatic castration-resistant prostate cancer (mCRPC)
-
abstr
-
Slovin, S.F., Beer, T.M., Higano, C.S., Tejwani, S., Hamid, O., Picus, J. et al. (2009) Initial phase II experience of ipilimumab (IPI) alone and in combination with radiotherapy (XRT) in patients with metastatic castration-resistant prostate cancer (mCRPC). J Clin Oncol 27(15s): abstr 5138.
-
(2009)
J Clin Oncol
, vol.27
, Issue.15s
, pp. 5138
-
-
Slovin, S.F.1
Beer, T.M.2
Higano, C.S.3
Tejwani, S.4
Hamid, O.5
Picus, J.6
-
121
-
-
0003274818
-
Epothilone B analogue (BMS-247550) with estramustine phosphate in patients with progressive castrate-metastatic prostate cancer
-
Smaletz, O., Kelly, W.K., Horse-Grant, D., Slovin, S.F., Morris, M.J., Solit, D.B. et al. (2002) Epothilone B analogue (BMS-247550) with estramustine phosphate in patients with progressive castrate-metastatic prostate cancer. Proceedings of the American Society of Clinical Oncology 21: 732.
-
(2002)
Proceedings of the American Society of Clinical Oncology
, vol.21
, pp. 732
-
-
Smaletz, O.1
Kelly, W.K.2
Horse-Grant, D.3
Slovin, S.F.4
Morris, M.J.5
Solit, D.B.6
-
122
-
-
0032809320
-
Therapy of advanced prostate cancer with granulocyte macrophage colony-stimulating factor
-
Small, E.J., Reese, D.M., Um, B., Whisenant, S., Dixon, S.C. and Figg, W.D. ( 1999) Therapy of advanced prostate cancer with granulocyte macrophage colony-stimulating factor. Clin Cancer Res 5: 1738-1744.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1738-1744
-
-
Small, E.J.1
Reese, D.M.2
Um, B.3
Whisenant, S.4
Dixon, S.C.5
Figg, W.D.6
-
123
-
-
0034554863
-
Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells
-
Small, E.J., Fratesi, P., Reese, D.M., Strang, G., Laus, R., Peshwa, M.V. et al. (2000) Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells. J Clin Oncol 18: 3894-3903.
-
(2000)
J Clin Oncol
, vol.18
, pp. 3894-3903
-
-
Small, E.J.1
Fratesi, P.2
Reese, D.M.3
Strang, G.4
Laus, R.5
Peshwa, M.V.6
-
124
-
-
33746012881
-
Placebo-controlled phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer
-
Small, E.J., Schellhammer, P.F., Higano, C.S., Redfern, C.H., Nemunaitis, J.J., Valone, F.H. et al. (2006) Placebo-controlled phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer. J Clin Oncol 24: 3089-3094.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3089-3094
-
-
Small, E.J.1
Schellhammer, P.F.2
Higano, C.S.3
Redfern, C.H.4
Nemunaitis, J.J.5
Valone, F.H.6
-
125
-
-
34447123763
-
Granulocyte macrophage colony-stimulating factor-secreting allogeneic cellular immunotherapy for hormone-refractory prostate cancer
-
Small, E.J., Sacks, N., Nemunaitis, J., Urba, W.J., Dula, E., Centeno, A.S. et al. (2007 a) Granulocyte macrophage colony-stimulating factor-secreting allogeneic cellular immunotherapy for hormone-refractory prostate cancer. Clin Cancer Res 13: 3883-3891.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 3883-3891
-
-
Small, E.J.1
Sacks, N.2
Nemunaitis, J.3
Urba, W.J.4
Dula, E.5
Centeno, A.S.6
-
126
-
-
34250223096
-
A pilot trial of CTLA-4 blockade with human anti-CTLA-4 in patients with hormone-refractory prostate cancer
-
Small, E.J., Tchekmedyian, N.S., Rini, B.I., Fong, L., Lowy, I. and Allison, J.P. ( 2007b) A pilot trial of CTLA-4 blockade with human anti-CTLA-4 in patients with hormone-refractory prostate cancer. Clin Cancer Res 13: 1810-1815.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1810-1815
-
-
Small, E.J.1
Tchekmedyian, N.S.2
Rini, B.I.3
Fong, L.4
Lowy, I.5
Allison, J.P.6
-
127
-
-
75249086516
-
Ixabepilone, mitoxantrone, and prednisone in patients with metastatic castration-resistant prostate cancer refractory to docetaxel-based therapy: a phase II study of the DOD Prostate Cancer Clinical Trials Consortium
-
abstr
-
Small, E., Harzstark, A., Weinberg, V.K., Smith, D.C., Mathew, P., Beer, T. et al. (2009 a) Ixabepilone, mitoxantrone, and prednisone in patients with metastatic castration-resistant prostate cancer refractory to docetaxel-based therapy: a phase II study of the DOD Prostate Cancer Clinical Trials Consortium. J Clin Oncol 27(15s): abstr 5058.
-
(2009)
J Clin Oncol
, vol.27
, Issue.15s
, pp. 5058
-
-
Small, E.1
Harzstark, A.2
Weinberg, V.K.3
Smith, D.C.4
Mathew, P.5
Beer, T.6
-
128
-
-
70349926513
-
A phase III trial of GVAX immunotherapy for prostate cancer in combination with docetaxel versus docetaxel plus prednisone in symptomatic, castration-resistant prostate cancer (CRPC)
-
ASCO Genitourinary Cancers Symposium (abstr 7)
-
Small, E., Demkow, T., Gerritsen, W.R., Rolland, F., Hoskin, P., Smith, D.C. et al. (2009 b) A phase III trial of GVAX immunotherapy for prostate cancer in combination with docetaxel versus docetaxel plus prednisone in symptomatic, castration-resistant prostate cancer (CRPC). ASCO Genitourinary Cancers Symposium (abstr 7).
-
(2009)
-
-
Small, E.1
Demkow, T.2
Gerritsen, W.R.3
Rolland, F.4
Hoskin, P.5
Smith, D.C.6
-
129
-
-
69049105440
-
(2009) Denosumab in men receiving androgen-deprivation therapy for prostate cancer
-
Smith, M.R., Egerdie, B., Toriz, N.H., Feldman, R., Tammela, T.L., Saad, F. et al. (2009) Denosumab in men receiving androgen-deprivation therapy for prostate cancer. N Engl J Med 361: 745-755.
-
N Engl J Med
, vol.361
, pp. 745-755
-
-
Smith, M.R.1
Egerdie, B.2
Toriz, N.H.3
Feldman, R.4
Tammela, T.L.5
Saad, F.6
-
130
-
-
20944439837
-
Phase III trial of satraplatin, an oral platinum plus prednisone vs. prednisone alone in patients with hormone-refractory prostate cancer
-
Sternberg, C.N., Whelan, P., Hetherington, J., Paluchowska, B., Slee, P.H., Vekemans, K. et al. (2005) Phase III trial of satraplatin, an oral platinum plus prednisone vs. prednisone alone in patients with hormone-refractory prostate cancer. Oncology 68: 2-9.
-
(2005)
Oncology
, vol.68
, pp. 2-9
-
-
Sternberg, C.N.1
Whelan, P.2
Hetherington, J.3
Paluchowska, B.4
Slee, P.H.5
Vekemans, K.6
-
131
-
-
73949098659
-
(2009 a) Multinational, double-blind, phase III study of prednisone and either satraplatin or placebo in patients with castrate-refractory prostate cancer progressing after prior chemotherapy: the SPARC trial
-
Sternberg, C.N., Petrylak, D.P., Sartor, O., Witjes, J.A., Demkow, T., Ferrero, J.M. et al. (2009 a) Multinational, double-blind, phase III study of prednisone and either satraplatin or placebo in patients with castrate-refractory prostate cancer progressing after prior chemotherapy: the SPARC trial. J Clin Oncol 27: 5431-5438.
-
J Clin Oncol
, vol.27
, pp. 5431-5438
-
-
Sternberg, C.N.1
Petrylak, D.P.2
Sartor, O.3
Witjes, J.A.4
Demkow, T.5
Ferrero, J.M.6
-
132
-
-
67650360358
-
(2009 b) Docetaxel plus oblimersen sodium (Bcl-2 antisense oligonucleotide): an EORTC multicenter, randomized phase II study in patients with castration-resistant prostate cancer
-
Sternberg, C.N., Dumez, H., van Poppel, H., Skoneczna, I., Sella, A., Daugaard, G. et al. (2009 b) Docetaxel plus oblimersen sodium (Bcl-2 antisense oligonucleotide): an EORTC multicenter, randomized phase II study in patients with castration-resistant prostate cancer. Ann Oncol 20: 1264-1269.
-
Ann Oncol
, vol.20
, pp. 1264-1269
-
-
Sternberg, C.N.1
Dumez, H.2
van Poppel, H.3
Skoneczna, I.4
Sella, A.5
Daugaard, G.6
-
133
-
-
4744366279
-
(2004) Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
-
Tannock, I.F., de Wit, R., Berry, W.R., Horti, J., Pluzanska, A., Chi, K.N. et al. (2004) Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N Engl J Med 351: 1502-1512.
-
N Engl J Med
, vol.351
, pp. 1502-1512
-
-
Tannock, I.F.1
de Wit, R.2
Berry, W.R.3
Horti, J.4
Pluzanska, A.5
Chi, K.N.6
-
134
-
-
27644591608
-
Properties of thalidomide and its analogues: implications for anticancer therapy
-
Teo, S.K. ( 2005) Properties of thalidomide and its analogues: implications for anticancer therapy. AAPS J 7: E14-E19.
-
(2005)
AAPS J
, vol.7
, pp. E14-E19
-
-
Teo, S.K.1
-
135
-
-
27644452640
-
Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer
-
Titus, M.A., Schell, M.J., Lih, F.B., Tomer, K.B. and Mohler, J.L. ( 2005) Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer. Clin Cancer Res 11: 4653-4657.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4653-4657
-
-
Titus, M.A.1
Schell, M.J.2
Lih, F.B.3
Tomer, K.B.4
Mohler, J.L.5
-
136
-
-
65649090203
-
(2009) Development of a second-generation antiandrogen for treatment of advanced prostate cancer
-
Tran, C., Ouk, S., Clegg, N.J., Chen, Y., Watson, P.A., Arora, V. et al. (2009) Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science 324: 787-90.
-
Science
, vol.324
, pp. 787-790
-
-
Tran, C.1
Ouk, S.2
Clegg, N.J.3
Chen, Y.4
Watson, P.A.5
Arora, V.6
-
137
-
-
70249148037
-
Phase I study of concurrent weekly docetaxel and repeated samarium-153 lexidronam in patients with castration-resistant metastatic prostate cancer
-
Tu, S.M., Mathew, P., Wong, F.C., Jones, D., Johnson, M.M. and Logothetis, C.J. ( 2009) Phase I study of concurrent weekly docetaxel and repeated samarium-153 lexidronam in patients with castration-resistant metastatic prostate cancer. J Clin Oncol 27: 3319-3324.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3319-3324
-
-
Tu, S.M.1
Mathew, P.2
Wong, F.C.3
Jones, D.4
Johnson, M.M.5
Logothetis, C.J.6
-
138
-
-
34547093162
-
Vascular endothelial growth factor trap blocks tumor growth, metastasis formation, and vascular leakage in an orthotopic murine renal cell cancer model
-
Verheul, H.M., Hammers, H., van Erp, K., Wei, Y., Sanni, T., Salumbides, B. et al. (2007) Vascular endothelial growth factor trap blocks tumor growth, metastasis formation, and vascular leakage in an orthotopic murine renal cell cancer model. Clin Cancer Res 13: 4201-4208.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4201-4208
-
-
Verheul, H.M.1
Hammers, H.2
van Erp, K.3
Wei, Y.4
Sanni, T.5
Salumbides, B.6
-
139
-
-
28444437086
-
Clinical trials involving vitamin D analogs in prostate cancer
-
Vijayakumar, S., Mehta, R.R., Boerner, P.S., Packianathan, S. and Mehta, R.G. ( 2005) Clinical trials involving vitamin D analogs in prostate cancer. Cancer J 11: 362-373.
-
(2005)
Cancer J
, vol.11
, pp. 362-373
-
-
Vijayakumar, S.1
Mehta, R.R.2
Boerner, P.S.3
Packianathan, S.4
Mehta, R.G.5
-
140
-
-
25144483466
-
Autoantibody signatures in prostate cancer
-
Wang, X., Yu, J., Sreekumar, A., Varambally, S., Shen, R., Giacherio, D. et al. (2005) Autoantibody signatures in prostate cancer. N Engl J Med 353: 1224-1235.
-
(2005)
N Engl J Med
, vol.353
, pp. 1224-1235
-
-
Wang, X.1
Yu, J.2
Sreekumar, A.3
Varambally, S.4
Shen, R.5
Giacherio, D.6
-
141
-
-
0034002814
-
Uses of granulocyte-macrophage colony-stimulating factor in vaccine development
-
Warren, T.L. and Weiner, G.J. ( 2000) Uses of granulocyte-macrophage colony-stimulating factor in vaccine development. Curr Opin Hematol 7: 168-173.
-
(2000)
Curr Opin Hematol
, vol.7
, pp. 168-173
-
-
Warren, T.L.1
Weiner, G.J.2
-
142
-
-
0037025173
-
Cancer. Addiction to oncogenes-the Achilles heal of cancer
-
Weinstein, I.B. ( 2002) Cancer. Addiction to oncogenes-the Achilles heal of cancer. Science 297: 63-64.
-
(2002)
Science
, vol.297
, pp. 63-64
-
-
Weinstein, I.B.1
-
143
-
-
59149089556
-
(2009) Histone deacetylases are required for androgen receptor function in hormone-sensitive and castrate-resistant prostate cancer
-
Welsbie, D.S., Xu, J., Chen, Y., Borsu, L., Scher, H.I., Rosen, N. et al. (2009) Histone deacetylases are required for androgen receptor function in hormone-sensitive and castrate-resistant prostate cancer. Cancer Res 69: 958-966.
-
Cancer Res
, vol.69
, pp. 958-966
-
-
Welsbie, D.S.1
Xu, J.2
Chen, Y.3
Borsu, L.4
Scher, H.I.5
Rosen, N.6
-
144
-
-
0032431032
-
The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway
-
Wu, X., Senechal, K., Neshat, M.S., Whang, Y.E. and Sawyers, C.L. ( 1998) The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway. Proc Natl Acad Sci U S A 95: 15587-15591.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 15587-15591
-
-
Wu, X.1
Senechal, K.2
Neshat, M.S.3
Whang, Y.E.4
Sawyers, C.L.5
-
145
-
-
17144416483
-
In vivo effects of the human type I insulin-like growth factor receptor antibody A 12 on androgen-dependent and androgen-independent xenograft human prostate tumors
-
Wu, J.D., Odman, A., Higgins, L.M., Haugk, K., Vessella, R., Ludwig, D.L. et al. (2005) In vivo effects of the human type I insulin-like growth factor receptor antibody A 12 on androgen-dependent and androgen-independent xenograft human prostate tumors. Clin Cancer Res 11: 3065-3074.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3065-3074
-
-
Wu, J.D.1
Odman, A.2
Higgins, L.M.3
Haugk, K.4
Vessella, R.5
Ludwig, D.L.6
-
146
-
-
84993703602
-
BAY 43-9006 (sorafenib) can lead to improvement of bone lesions in metastatic androgen-independent prostate cancer despite rises in serum PSA levels
-
Proceedings of the Prostate Cancer Symposium, Abstract 259. 24-26 February 2006 American Society of Clinical Oncology: Orlando, FL
-
Wu, S., Posadas, E. and Scripture, C. ( 2006) BAY 43-9006 (sorafenib) can lead to improvement of bone lesions in metastatic androgen-independent prostate cancer despite rises in serum PSA levels. Proceedings of the Prostate Cancer Symposium, Abstract 259. 24-26 February 2006. American Society of Clinical Oncology: Orlando, FL.
-
(2006)
-
-
Wu, S.1
Posadas, E.2
Scripture, C.3
-
147
-
-
0034016273
-
Treatment for malignant pleural effusion of human lung adenocarcinoma by inhibition of vascular endothelial growth factor receptor tyrosine kinase phosphorylation
-
Yano, S., Herbst, R.S., Shinohara, H., Knighton, B., Bucana, C.D., Killion, J.J. et al. (2000) Treatment for malignant pleural effusion of human lung adenocarcinoma by inhibition of vascular endothelial growth factor receptor tyrosine kinase phosphorylation. Clin Cancer Res 6: 957-965.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 957-965
-
-
Yano, S.1
Herbst, R.S.2
Shinohara, H.3
Knighton, B.4
Bucana, C.D.5
Killion, J.J.6
-
148
-
-
0036796026
-
Enhanced radiation sensitivity in prostate cancer by inhibition of the cell survival protein clusterin
-
Zellweger, T., Chi, K., Miyake, H., Adomat, H., Kiyama, S., Skov, K. et al. (2002) Enhanced radiation sensitivity in prostate cancer by inhibition of the cell survival protein clusterin. Clin Cancer Res 8: 3276-3284.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 3276-3284
-
-
Zellweger, T.1
Chi, K.2
Miyake, H.3
Adomat, H.4
Kiyama, S.5
Skov, K.6
-
149
-
-
26944445883
-
Clusterin inhibits apoptosis by interacting with activated Bax
-
Zhang, H., Kim, J.K., Edwards, C.A., Xu, Z., Taichman, R. and Wang, C.Y. ( 2005) Clusterin inhibits apoptosis by interacting with activated Bax. Nat Cell Biol 7: 909-915.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 909-915
-
-
Zhang, H.1
Kim, J.K.2
Edwards, C.A.3
Xu, Z.4
Taichman, R.5
Wang, C.Y.6
-
150
-
-
3943104783
-
The use of trastuzumab in the treatment of hormone refractory prostate cancer; phase II trial
-
Ziada, A., Barqawi, A., Glode, L.M., Varella-Garcia, M., Crighton, F., Majeski, S. et al. (2004) The use of trastuzumab in the treatment of hormone refractory prostate cancer; phase II trial. Prostate 60: 332-337.
-
(2004)
Prostate
, vol.60
, pp. 332-337
-
-
Ziada, A.1
Barqawi, A.2
Glode, L.M.3
Varella-Garcia, M.4
Crighton, F.5
Majeski, S.6
|