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Volumn 107, Issue 29, 2010, Pages 13069-13074

Efficacy of bortezomib in a direct xenograft model of primary effusion lymphoma

Author keywords

Herpesvirus 8; Kaposi's sarcoma associated herpesvirus

Indexed keywords

BORTEZOMIB; DOXORUBICIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR E2F3; TRANSCRIPTOME;

EID: 77955590822     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1002985107     Document Type: Article
Times cited : (73)

References (49)
  • 1
    • 0028588064 scopus 로고
    • Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma
    • Chang Y, et al. (1994) Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 266:1865-1869.
    • (1994) Science , vol.266 , pp. 1865-1869
    • Chang, Y.1
  • 2
    • 0029069445 scopus 로고
    • Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas
    • Cesarman E, Chang Y, Moore PS, Said JW, Knowles DM (1995) Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. N Engl J Med 332:1186-1191.
    • (1995) N Engl J Med , vol.332 , pp. 1186-1191
    • Cesarman, E.1    Chang, Y.2    Moore, P.S.3    Said, J.W.4    Knowles, D.M.5
  • 3
    • 0032981813 scopus 로고    scopus 로고
    • The role of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) in lymphoproliferative diseases
    • DOI 10.1006/scbi.1998.0118
    • Cesarman E, Knowles DM (1999) The role of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) in lymphoproliferative diseases. Semin Cancer Biol 9:165-174. (Pubitemid 29273833)
    • (1999) Seminars in Cancer Biology , vol.9 , Issue.3 , pp. 165-174
    • Cesarman, E.1    Knowles, D.M.2
  • 8
    • 0034600309 scopus 로고    scopus 로고
    • Monoclonality or oligoclonality of human herpesvirus 8 terminal repeat sequences in Kaposi's sarcoma and other diseases
    • Judde J-G, et al. (2000) Monoclonality or oligoclonality of human herpesvirus 8 terminal repeat sequences in Kaposi's sarcoma and other diseases. J Natl Cancer Inst 92:729-736.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 729-736
    • Judde, J.-G.1
  • 9
    • 0035100879 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 1 mediates episome persistence through cis-acting terminal repeat (TR) sequence and specifically binds TR DNA
    • Ballestas ME, Kaye KM (2001) Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 1 mediates episome persistence through cis-acting terminal repeat (TR) sequence and specifically binds TR DNA. J Virol 75:3250-3258.
    • (2001) J Virol , vol.75 , pp. 3250-3258
    • Ballestas, M.E.1    Kaye, K.M.2
  • 12
    • 1842631466 scopus 로고    scopus 로고
    • KSHV vFLIP Is Essential for the Survival of Infected Lymphoma Cells
    • DOI 10.1084/jem.20031467
    • Guasparri I, Keller SA, Cesarman E (2004) KSHV vFLIP is essential for the survival of infected lymphoma cells. J Exp Med 199:993-1003. (Pubitemid 38481090)
    • (2004) Journal of Experimental Medicine , vol.199 , Issue.7 , pp. 993-1003
    • Guasparri, I.1    Keller, S.A.2    Cesarman, E.3
  • 14
    • 0035950522 scopus 로고    scopus 로고
    • Induction of a TRAIL-mediated suicide program by interferon alpha in primary effusion lymphoma
    • Toomey NL, et al. (2001) Induction of a TRAIL-mediated suicide program by interferon alpha in primary effusion lymphoma. Oncogene 20:7029-7040.
    • (2001) Oncogene , vol.20 , pp. 7029-7040
    • Toomey, N.L.1
  • 15
    • 14744278052 scopus 로고    scopus 로고
    • Inhibition of HHV-8/ KSHV infected primary effusion lymphomas in NOD/SCID mice by azidothymidine and interferon-alpha
    • Wu W, Rochford R, Toomey L, Harrington W, Jr, Feuer G (2005) Inhibition of HHV-8/ KSHV infected primary effusion lymphomas in NOD/SCID mice by azidothymidine and interferon-alpha. Leuk Res 29:545-555.
    • (2005) Leuk Res , vol.29 , pp. 545-555
    • Wu, W.1    Rochford, R.2    Toomey, L.3    Harrington Jr., W.4    Feuer, G.5
  • 16
    • 0034287445 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB induces apoptosis of KSHV-infected primary effusion lymphoma cells
    • Keller SA, Schattner EJ, Cesarman E (2000) Inhibition of NF-kappaB induces apoptosis of KSHV-infected primary effusion lymphoma cells. Blood 96:2537-2542.
    • (2000) Blood , vol.96 , pp. 2537-2542
    • Keller, S.A.1    Schattner, E.J.2    Cesarman, E.3
  • 17
    • 6344265692 scopus 로고    scopus 로고
    • Antitumor effects of bortezomib (PS-341) on primary effusion lymphomas
    • An J, Sun Y, Fisher M, Rettig MB (2004) Antitumor effects of bortezomib (PS-341) on primary effusion lymphomas. Leukemia 18:1699-1704.
    • (2004) Leukemia , vol.18 , pp. 1699-1704
    • An, J.1    Sun, Y.2    Fisher, M.3    Rettig, M.B.4
  • 18
    • 18544373405 scopus 로고    scopus 로고
    • The targeting of primary effusion lymphoma cells for apoptosis by inducing lytic replication of human herpesvirus 8 while blocking virus production
    • Klass CM, Krug LT, Pozharskaya VP, Offermann MK (2005) The targeting of primary effusion lymphoma cells for apoptosis by inducing lytic replication of human herpesvirus 8 while blocking virus production. Blood 105:4028-4034.
    • (2005) Blood , vol.105 , pp. 4028-4034
    • Klass, C.M.1    Krug, L.T.2    Pozharskaya, V.P.3    Offermann, M.K.4
  • 19
    • 3142692564 scopus 로고    scopus 로고
    • The tumor microenvironment controls primary effusion lymphoma growth in vivo
    • Staudt MR, et al. (2004) The tumor microenvironment controls primary effusion lymphoma growth in vivo. Cancer Res 64:4790-4799.
    • (2004) Cancer Res , vol.64 , pp. 4790-4799
    • Staudt, M.R.1
  • 20
    • 0033901248 scopus 로고    scopus 로고
    • Differential viral protein expression in Kaposi's sarcoma-associated herpesvirus-infected diseases: Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease
    • Parravicini C, et al. (2000) Differential viral protein expression in Kaposi's sarcoma-associated herpesvirus-infected diseases: Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease. Am J Pathol 156:743-749.
    • (2000) Am J Pathol , vol.156 , pp. 743-749
    • Parravicini, C.1
  • 21
    • 33744539521 scopus 로고    scopus 로고
    • Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells
    • Obeng EA, et al. (2006) Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells. Blood 107:4907-4916.
    • (2006) Blood , vol.107 , pp. 4907-4916
    • Obeng, E.A.1
  • 22
    • 15944387964 scopus 로고    scopus 로고
    • The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim
    • Nikrad M, et al. (2005) The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim. Mol Cancer Ther 4: 443-449.
    • (2005) Mol Cancer Ther , vol.4 , pp. 443-449
    • Nikrad, M.1
  • 23
    • 20444433230 scopus 로고    scopus 로고
    • Bortezomib or high-dose dexamethasone for relapsed multiple myeloma
    • Assessment of Proteasome Inhibition for Extending Remissions (APEX) Investigators
    • Richardson PG, et al.; Assessment of Proteasome Inhibition for Extending Remissions (APEX) Investigators (2005) Bortezomib or high-dose dexamethasone for relapsed multiple myeloma. N Engl J Med 352:2487-2498.
    • (2005) N Engl J Med , vol.352 , pp. 2487-2498
    • Richardson, P.G.1
  • 24
    • 20044376092 scopus 로고    scopus 로고
    • Phase II clinical experience with the novel proteasome inhibitor bortezomib in patients with indolent non-Hodgkin's lymphoma and mantle cell lymphoma
    • O'Connor OA, et al. (2005) Phase II clinical experience with the novel proteasome inhibitor bortezomib in patients with indolent non-Hodgkin's lymphoma and mantle cell lymphoma. J Clin Oncol 23:676-684.
    • (2005) J Clin Oncol , vol.23 , pp. 676-684
    • O'Connor, O.A.1
  • 25
    • 33645744753 scopus 로고    scopus 로고
    • The KSHV oncoprotein vFLIP contains a TRAF-interacting motif and requires TRAF2 and TRAF3 for signalling
    • Guasparri I, Wu H, Cesarman E (2006) The KSHV oncoprotein vFLIP contains a TRAF-interacting motif and requires TRAF2 and TRAF3 for signalling. EMBO Rep 7:114-119.
    • (2006) EMBO Rep , vol.7 , pp. 114-119
    • Guasparri, I.1    Wu, H.2    Cesarman, E.3
  • 26
    • 0042337395 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus-infected primary effusion lymphoma has a plasma cell gene expression profile
    • Jenner RG, et al. (2003) Kaposi's sarcoma-associated herpesvirus-infected primary effusion lymphoma has a plasma cell gene expression profile. Proc Natl Acad Sci USA 100:10399-10404.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10399-10404
    • Jenner, R.G.1
  • 27
    • 0031713755 scopus 로고    scopus 로고
    • Lymphoma cell lines: In vitro models for the study of HHV-8+ primary effusion lymphomas (body cavity-based lymphomas)
    • Drexler HG, Uphoff CC, Gaidano G, Carbone A (1998) Lymphoma cell lines: In vitro models for the study of HHV-8+ primary effusion lymphomas (body cavity-based lymphomas). Leukemia 12:1507-1517.
    • (1998) Leukemia , vol.12 , pp. 1507-1517
    • Drexler, H.G.1    Uphoff, C.C.2    Gaidano, G.3    Carbone, A.4
  • 28
    • 15944366885 scopus 로고    scopus 로고
    • The ER chaperone and signaling regulator GRP78/BiP as a monitor of endoplasmic reticulum stress
    • Lee AS (2005) The ER chaperone and signaling regulator GRP78/BiP as a monitor of endoplasmic reticulum stress. Methods 35 (4):373-381.
    • (2005) Methods , vol.35 , Issue.4 , pp. 373-381
    • Lee, A.S.1
  • 29
    • 0023878562 scopus 로고
    • The catalytic mechanism of guanine nucleotide exchange factor action and competitive inhibition by phosphorylated eukaryotic initiation factor 2
    • Rowlands AG, Panniers R, Henshaw EC (1988) The catalytic mechanism of guanine nucleotide exchange factor action and competitive inhibition by phosphorylated eukaryotic initiation factor 2. J Biol Chem 263:5526-5533.
    • (1988) J Biol Chem , vol.263 , pp. 5526-5533
    • Rowlands, A.G.1    Panniers, R.2    Henshaw, E.C.3
  • 30
    • 0033634654 scopus 로고    scopus 로고
    • Regulated translation initiation controls stress-induced gene expression in mammalian cells
    • Harding HP, et al. (2000) Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell 6:1099-1108.
    • (2000) Mol Cell , vol.6 , pp. 1099-1108
    • Harding, H.P.1
  • 31
    • 33845187907 scopus 로고    scopus 로고
    • Global mapping of c-Myc binding sites and target gene networks in human B cells
    • Zeller KI, et al. (2006) Global mapping of c-Myc binding sites and target gene networks in human B cells. Proc Natl Acad Sci USA 103:17834-17839.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 17834-17839
    • Zeller, K.I.1
  • 32
    • 31144459985 scopus 로고    scopus 로고
    • Oncogenic pathway signatures in human cancers as a guide to targeted therapies
    • Bild AH, et al. (2006) Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature 439:353-357.
    • (2006) Nature , vol.439 , pp. 353-357
    • Bild, A.H.1
  • 33
    • 35348818721 scopus 로고    scopus 로고
    • Induction of heme oxygenase-1 by cobalt protoporphyrin enhances the antitumour effect of bortezomib in adult T-cell leukaemia cells
    • Hamamura RS, et al. (2007) Induction of heme oxygenase-1 by cobalt protoporphyrin enhances the antitumour effect of bortezomib in adult T-cell leukaemia cells. Br J Cancer 97:1099-1105.
    • (2007) Br J Cancer , vol.97 , pp. 1099-1105
    • Hamamura, R.S.1
  • 34
    • 0035300479 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
    • Hideshima T, et al. (2001) The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res 61:3071-3076.
    • (2001) Cancer Res , vol.61 , pp. 3071-3076
    • Hideshima, T.1
  • 35
    • 0842286712 scopus 로고    scopus 로고
    • The KSHV G protein-coupled receptor signals via multiple pathways to induce transcription factor activation in primary effusion lymphoma cells
    • Cannon ML, Cesarman E (2004) The KSHV G protein-coupled receptor signals via multiple pathways to induce transcription factor activation in primary effusion lymphoma cells. Oncogene 23:514-523.
    • (2004) Oncogene , vol.23 , pp. 514-523
    • Cannon, M.L.1    Cesarman, E.2
  • 36
    • 0035866812 scopus 로고    scopus 로고
    • The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor promotes endothelial cell survival through the activation of Akt/protein kinase B
    • Montaner S, Sodhi A, Pece S, Mesri EA, Gutkind JS (2001) The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor promotes endothelial cell survival through the activation of Akt/protein kinase B. Cancer Res 61:2641-2648.
    • (2001) Cancer Res , vol.61 , pp. 2641-2648
    • Montaner, S.1    Sodhi, A.2    Pece, S.3    Mesri, E.A.4    Gutkind, J.S.5
  • 37
    • 77953932867 scopus 로고    scopus 로고
    • Dual inhibition of PI3K and mTOR inhibits autocrine and paracrine proliferative loops in PI3K/Akt/mTOR-addicted lymphomas
    • Bhatt AP, et al. (2010) Dual inhibition of PI3K and mTOR inhibits autocrine and paracrine proliferative loops in PI3K/Akt/mTOR-addicted lymphomas. Blood 115: 4455-4463.
    • (2010) Blood , vol.115 , pp. 4455-4463
    • Bhatt, A.P.1
  • 38
    • 66449131460 scopus 로고    scopus 로고
    • Bortezomib overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells in part through the inhibition of the phosphatidylinositol 3-kinase/Akt pathway
    • Chen KF, et al. (2009) Bortezomib overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells in part through the inhibition of the phosphatidylinositol 3-kinase/Akt pathway. J Biol Chem 284: 11121-11133.
    • (2009) J Biol Chem , vol.284 , pp. 11121-11133
    • Chen, K.F.1
  • 39
    • 34547425829 scopus 로고    scopus 로고
    • Deregulation of c-Myc in primary effusion lymphoma by Kaposi's sarcoma herpesvirus latency-associated nuclear antigen
    • Bubman D, Guasparri I, Cesarman E (2007) Deregulation of c-Myc in primary effusion lymphoma by Kaposi's sarcoma herpesvirus latency-associated nuclear antigen. Oncogene 26:4979-4986.
    • (2007) Oncogene , vol.26 , pp. 4979-4986
    • Bubman, D.1    Guasparri, I.2    Cesarman, E.3
  • 40
    • 0033180211 scopus 로고    scopus 로고
    • Reversible tumorigenesis by MYC in hematopoietic lineages
    • Felsher DW, Bishop JM (1999) Reversible tumorigenesis by MYC in hematopoietic lineages. Mol Cell 4:199-207.
    • (1999) Mol Cell , vol.4 , pp. 199-207
    • Felsher, D.W.1    Bishop, J.M.2
  • 42
    • 1642430733 scopus 로고    scopus 로고
    • Myc pathways provoking cell suicide and cancer
    • Nilsson JA, Cleveland JL (2003) Myc pathways provoking cell suicide and cancer. Oncogene 22:9007-9021.
    • (2003) Oncogene , vol.22 , pp. 9007-9021
    • Nilsson, J.A.1    Cleveland, J.L.2
  • 43
    • 77449155831 scopus 로고    scopus 로고
    • Novel IL-21 signaling pathway up-regulates c-Myc and induces apoptosis of diffuse large B-cell lymphomas
    • Sarosiek KA, et al. (2010) Novel IL-21 signaling pathway up-regulates c-Myc and induces apoptosis of diffuse large B-cell lymphomas. Blood 115:570-580.
    • (2010) Blood , vol.115 , pp. 570-580
    • Sarosiek, K.A.1
  • 44
    • 25444459935 scopus 로고    scopus 로고
    • Prostratin and bortezomib are novel inducers of latent Kaposi's sarcoma-associated herpesvirus
    • Brown HJ, McBride WH, Zack JA, Sun R (2005) Prostratin and bortezomib are novel inducers of latent Kaposi's sarcoma-associated herpesvirus. Antivir Ther 10:745-751.
    • (2005) Antivir Ther , vol.10 , pp. 745-751
    • Brown, H.J.1    McBride, W.H.2    Zack, J.A.3    Sun, R.4
  • 45
    • 0029796383 scopus 로고    scopus 로고
    • Establishment and characterization of a primary effusion (body cavity-based) lymphoma cell line (BC-3) harboring Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) in the absence of Epstein-Barr virus
    • Arvanitakis L, et al. (1996) Establishment and characterization of a primary effusion (body cavity-based) lymphoma cell line (BC-3) harboring Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) in the absence of Epstein-Barr virus. Blood 88:2648-2654.
    • (1996) Blood , vol.88 , pp. 2648-2654
    • Arvanitakis, L.1
  • 46
    • 22044458584 scopus 로고    scopus 로고
    • Azidothymidine inhibits NF-kappaB and induces Epstein- Barr virus gene expression in Burkitt lymphoma
    • Kurokawa M, et al. (2005) Azidothymidine inhibits NF-kappaB and induces Epstein- Barr virus gene expression in Burkitt lymphoma. Blood 106:235-240.
    • (2005) Blood , vol.106 , pp. 235-240
    • Kurokawa, M.1
  • 47
    • 33847619373 scopus 로고    scopus 로고
    • In vivo-restricted and reversible malignancy induced by human herpesvirus-8 KSHV: A cell and animal model of virally induced Kaposi's sarcoma
    • Mutlu AD, et al. (2007) In vivo-restricted and reversible malignancy induced by human herpesvirus-8 KSHV: A cell and animal model of virally induced Kaposi's sarcoma. Cancer Cell 11:245-258.
    • (2007) Cancer Cell , vol.11 , pp. 245-258
    • Mutlu, A.D.1
  • 48
    • 0034161392 scopus 로고    scopus 로고
    • Molecular analysis of immunoglobulin genes in diffuse large Bcell lymphomas
    • Lossos IS, et al. (2000) Molecular analysis of immunoglobulin genes in diffuse large Bcell lymphomas. Blood 95:1797-1803.
    • (2000) Blood , vol.95 , pp. 1797-1803
    • Lossos, I.S.1
  • 49
    • 70350014904 scopus 로고    scopus 로고
    • Interleukin-4 distinctively modifies responses of germinal centre-like and activated B-cell-like diffuse large B-cell lymphomas to immuno-chemotherapy
    • Sarosiek KA, Nechushtan H, Lu X, Rosenblatt JD, Lossos IS (2009) Interleukin-4 distinctively modifies responses of germinal centre-like and activated B-cell-like diffuse large B-cell lymphomas to immuno-chemotherapy. Br J Haematol 147: 308-318.
    • (2009) Br J Haematol , vol.147 , pp. 308-318
    • Sarosiek, K.A.1    Nechushtan, H.2    Lu, X.3    Rosenblatt, J.D.4    Lossos, I.S.5


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