Inhibition of cell proliferation, adhesion, and invasion with an anti-L1-cell adhesion molecule monoclonal antibody in an in vitro endometriosis model

Fertility and Sterility

Volumn 94, Issue 3, 2010, Pages 1102-1104

  Agic, Admir ^a   Von Wussow, Ursula ^a   Starzinski Powitz, Anna ^b   Diedrich, Klaus ^a   Altevogt, Peter ^c   Hornung, Daniela ^a  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b GOETHE UNIVERSITY   (Germany)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI L1 CELL ADHESION MOLECULE MONOCLONAL ANTIBODY; CELL ADHESION MOLECULE; IMMUNOGLOBULIN G ANTIBODY; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ANGIOGENESIS; ARTICLE; ASCITES; CELL ADHESION; CELL CULTURE; CELL DEATH; CELL INVASION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE COURSE; ENDOMETRIOSIS; GROWTH INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INFLAMMATION; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL;

ANTIBODIES, MONOCLONAL; CELL ADHESION; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; DOWN-REGULATION; DRUG EVALUATION, PRECLINICAL; ENDOMETRIOSIS; FEMALE; HUMANS; MODELS, BIOLOGICAL; NEURAL CELL ADHESION MOLECULE L1; PERITONEAL DISEASES;

EID: 77955566632     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2009.11.050     Document Type: Article

References (28)

1. C.A. Witz, K.T. Allsup, I.A. Montoya-Rodriguez, S.L. Vaughan, V.E. Centonze, and R.S. Schenken Pathogenesis of endometriosis - current research Hum Fertil (Camb) 6 2003 34 40
2. F.G. Rathjen, and M. Schachner Immunocytological and biochemical characterization of a new neuronal cell surface component (L1CAM antigen) which is involved in cell adhesion Embo J 3 1984 1 10
3. A.M. Montgomery, J.C. Becker, C.H. Siu, V.P. Lemmon, D.A. Cheresh, and J.D. Pancook Human neural cell adhesion molecule L1 and rat homologue NILE are ligands for integrin alpha v beta 3 J Cell Biol 132 1996 475 485
4. M. Schachner Neural recognition molecules and synaptic plasticity Curr Opin Cell Biol 9 1997 627 634
5. M. Hortsch Structural and functional evolution of the L1CAM family: are four adhesion molecules better than one? Mol Cell Neurosci 15 2000 1 10
6. F. Meier, S. Busch, D. Gast, A. Goppert, P. Altevogt, and E. Maczey The adhesion molecule L1 (CD171) promotes melanoma progression Int J Cancer 119 2006 549 555
7. M. Huszar, G. Moldenhauer, V. Gschwend, A. Ben-Arie, P. Altevogt, and M. Fogel Expression profile analysis in multiple human tumors identifies L1 (CD171) as a molecular marker for differential diagnosis and targeted therapy Hum Pathol 37 2006 1000 1008
8. J.T. Kaifi, A. Strelow, P.G. Schurr, U. Reichelt, E.F. Yekebas, and R. Wachowiak L1 (CD171) is highly expressed in gastrointestinal stromal tumors Mod Pathol 19 2006 399 406
9. M. Fogel, P. Gutwein, S. Mechtersheimer, S. Riedle, A. Stoeck, and A. Smirnov L1 expression as a predictor of progression and survival in patients with uterine and ovarian carcinomas Lancet 362 2003 869 875
10. T. Ohnishi, H. Matsumura, S. Izumoto, S. Hiraga, and T. Hayakawa A novel model of glioma cell invasion using organotypic brain slice culture Cancer Res 58 1998 2935 2940
11. S. Mechtersheimer, P. Gutwein, N. Agmon-Levin, A. Stoeck, M. Oleszewski, and S. Riedle Ectodomain shedding of L1CAM adhesion molecule promotes cell migration by autocrine binding to integrins J Cell Biol 155 2001 661 673
12. E.B. Voura, R.A. Ramjeesingh, A.M. Montgomery, and C.H. Siu Involvement of integrin alpha(v)beta(3) and cell adhesion molecule L1 in transendothelial migration of melanoma cells Mol Biol Cell 12 2001 2699 2710
13. A. Zeitvogel, R. Baumann, and A. Starzinski-Powitz Identification of an invasive, N-cadherin-expressing epithelial cell type in endometriosis using a new cell culture model Am J Pathol 159 2001 1839 1852
14. D. Finas, M. Huszar, A. Agic, S. Dogan, H. Kiefel, and S. Riedle L1 cell adhesion molecule (L1CAM) as a pathogenetic factor in endometriosis Hum Reprod 23 2008 1053 1062
15. H. Hall, and J.A. Hubbell Matrix-bound sixth Ig-like domain of cell adhesion molecule L1 acts as an angiogenic factor by ligating αvβ3-integrin and activating VEGF-R2 Microvasc Res 68 2004 169 178
16. J. Haspel, and M. Grumet The L1CAM extracellular region: a multi-domain protein with modular and cooperative binding modes Front Biosci 8 2003 1210 1225
17. P. Gutwein, A. Stoeck, S. Riedle, D. Gast, S. Runz, and T.P. Condon Cleavage of L1 in exosomes and apoptotic membrane vesicles released from ovarian carcinoma cells Clin Cancer Res 11 2005 2492 2501
18. A.F. Haney, J.J. Muscato, and J.B. Weinberg Peritoneal fluid cell populations in infertility patients Fertil Steril 35 1981 696 698
19. D.L. Olive, J.B. Weinberg, and A.F. Haney Peritoneal macrophages and infertility: the association between cell number and pelvic pathology Fertil Steril 44 1985 772 777
20. J. Rugtveit, P. Brandtzaeg, T.S. Halstensen, O. Fausa, and H. Scott Increased macrophage subset in inflammatory bowel disease: apparent recruitment from peripheral blood monocytes Gut 35 1994 669 674
21. A. Kowitz, G. Kadmon, M. Eckert, V. Schirrmacher, M. Schachner, and P. Altevogt Expression and function of the neural cell adhesion molecule L1 in mouse leukocytes Eur J Immunol 22 1992 1199 1205
22. O. Ebeling, A. Duczmal, S. Aigner, C. Geiger, S. Schollhammer, and J.T. Kemshead L1 adhesion molecule on human lymphocytes and monocytes: expression and involvement in binding to alpha v beta 3 integrin Eur J Immunol 26 1996 2508 2516
23. A. Duczmal, S. Schollhammer, S. Katich, O. Ebeling, R. Schwartz-Albiez, and P. Altevogt The L1 adhesion molecule supports alpha v beta 3-mediated migration of human tumor cells and activated T lymphocytes Biochem Biophys Res Commun 232 1997 236 239
24. P. Brandtzaeg, I. Dale, and M.K. Fagerhol Distribution of a formalin-resistant myelomonocytic antigen (L1) in human tissues. I. Comparison with other leukocyte markers by paired immunofluorescence and immunoenzyme staining Am J Clin Pathol 87 1987 681 699
25. D. Hornung, F. Bentzien, D. Wallwiener, and L. Kiesel Taylor RN Chemokine bioactivity of RANTES in endometriotic and normal endometrial stromal cells and peritoneal fluid Mol Hum Reprod 7 2001 163 168
26. J.D. Pancook, R.A. Reisfeld, N. Varki, A. Vitiello, R.I. Fox, and A.M. Montgomery Expression and regulation of the neural cell adhesion molecule L1 on human cells of myelomonocytic and lymphoid origin J Immunol 158 1997 4413 4421
27. B. Felding-Habermann, S. Silletti, F. Mei, C.H. Siu, P.M. Yip, and P.C. Brooks A single immunoglobulin-like domain of the human neural cell adhesion molecule L1CAM supports adhesion by multiple vascular and platelet integrins J Cell Biol 139 1997 1567 1581
28. M.J. Arlt, I. Novak-Hofer, D. Gast, V. Gschwend, G. Moldenhauer, and J. Grunberg Efficient inhibition of intra-peritoneal tumor growth and dissemination of human ovarian carcinoma cells in nude mice by anti-L1CAM-cell adhesion molecule monoclonal antibody treatment Cancer Res 66 2006 936 943