메뉴 건너뛰기




Volumn 87, Issue 6, 2010, Pages 2125-2135

Functional analysis of glycoside hydrolase family 8 xylanases shows narrow but distinct substrate specificities and biotechnological potential

Author keywords

Arabinoxylan; Glycoside hydrolase family 8; Substrate specificity; Xylanase; Xylo oligosaccharides

Indexed keywords

ARABINOXYLANS; GLYCOSIDE HYDROLASES; SUBSTRATE SPECIFICITY; XYLANASES; XYLO- OLIGOSACCHARIDES;

EID: 77955561000     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-010-2659-3     Document Type: Article
Times cited : (28)

References (41)
  • 1
    • 0343036237 scopus 로고    scopus 로고
    • Endo-β-1,4-xylanase families: Differences in catalytic properties
    • DOI 10.1016/S0168-1656(97)00096-5, PII S0168165697000965
    • P Biely M Vrsanska M Tenkanen D Kluepfel 1997 Endo-β-1, 4-xylanase families: differences in catalytic properties J Biotechnol 57 151 166 10.1016/S0168-1656(97)00096-5 1:CAS:528:DyaK2sXmvVarsb8%3D (Pubitemid 27397479)
    • (1997) Journal of Biotechnology , vol.57 , Issue.1-3 , pp. 151-166
    • Biely, P.1    Vrsanska, M.2    Tenkanen, M.3    Kluepfel, D.4
  • 3
    • 84899165966 scopus 로고    scopus 로고
    • Prebiotic and other health-related effects of cereal-derived arabinoxylans, arabinoxylan-oligosaccharides and xylo-oligosaccharides
    • Accepted for publication
    • Broekaert WF, Courtin CA, Verbeke K, Van de Wiele T, Verstraete W, Delcour JA (2010) Prebiotic and other health-related effects of cereal-derived arabinoxylans, arabinoxylan-oligosaccharides and xylo-oligosaccharides. Crit Rev Food Sci Nutr, Accepted for publication
    • (2010) Crit Rev Food Sci Nutr
    • Broekaert, W.F.1    Courtin, C.A.2    Verbeke, K.3    Van De Wiele, T.4    Verstraete, W.5    Delcour, J.A.6
  • 4
    • 0028579789 scopus 로고
    • Application of xylanases in the pulp and paper industry
    • 10.1016/0960-8524(94)90222-4 1:CAS:528:DyaK2MXktVKhu7Y%3D
    • J Buchert M Tenkanen A Kantelinen L Viikari 1994 Application of xylanases in the pulp and paper industry Bioresour Technol 50 65 72 10.1016/0960-8524(94) 90222-4 1:CAS:528:DyaK2MXktVKhu7Y%3D
    • (1994) Bioresour Technol , vol.50 , pp. 65-72
    • Buchert, J.1    Tenkanen, M.2    Kantelinen, A.3    Viikari, L.4
  • 5
    • 44449106703 scopus 로고    scopus 로고
    • Xylanases and their applications in baking industry
    • 1:CAS:528:DC%2BD1cXlvVGqtb0%3D
    • MS Butt M Tahir-Nadeem Z Ahmad MT Sultan 2008 Xylanases and their applications in baking industry Food Technol Biotechnol 46 22 31 1:CAS:528:DC%2BD1cXlvVGqtb0%3D
    • (2008) Food Technol Biotechnol , vol.46 , pp. 22-31
    • Butt, M.S.1    Tahir-Nadeem, M.2    Ahmad, Z.3    Sultan, M.T.4
  • 6
    • 58149200943 scopus 로고    scopus 로고
    • The Carbohydrate-Active EnZymes database (CAZy): An expert resource for glycogenomics
    • 10.1093/nar/gkn663 1:CAS:528:DC%2BD1cXhsFejtL7K
    • BL Cantarel PM Coutinho C Rancurel T Bernard V Lombard B Henrissat 2009 The Carbohydrate-Active EnZymes database (CAZy): an expert resource for glycogenomics Nucleic Acids Res 37 D233 D238 10.1093/nar/gkn663 1:CAS:528:DC%2BD1cXhsFejtL7K
    • (2009) Nucleic Acids Res , vol.37
    • Cantarel, B.L.1    Coutinho, P.M.2    Rancurel, C.3    Bernard, T.4    Lombard, V.5    Henrissat, B.6
  • 7
    • 0037144574 scopus 로고    scopus 로고
    • A novel family 8 xylanase, functional and physicochemical characterization
    • 10.1074/jbc.M204517200 1:CAS:528:DC%2BD38Xnt1Wgurg%3D
    • T Collins MA Meuwis I Stals M Claeyssens G Feller C Gerday 2002 A novel family 8 xylanase, functional and physicochemical characterization J Biol Chem 277 35133 35139 10.1074/jbc.M204517200 1:CAS:528:DC%2BD38Xnt1Wgurg%3D
    • (2002) J Biol Chem , vol.277 , pp. 35133-35139
    • Collins, T.1    Meuwis, M.A.2    Stals, I.3    Claeyssens, M.4    Feller, G.5    Gerday, C.6
  • 9
    • 0031439907 scopus 로고    scopus 로고
    • Assembly and enlargement of the primary cell wall in plants
    • DOI 10.1146/annurev.cellbio.13.1.171
    • DJ Cosgrove 1997 Assembly and enlargement of the primary cell wall in plants Annu Rev Cell Dev Biol 13 171 201 10.1146/annurev.cellbio.13.1.171 1:CAS:528:DyaK1cXisFSksQ%3D%3D (Pubitemid 28034524)
    • (1997) Annual Review of Cell and Developmental Biology , vol.13 , pp. 171-201
    • Cosgrove, D.J.1
  • 10
    • 0036315660 scopus 로고    scopus 로고
    • Arabinoxylans and endoxylanases in wheat flour bread-making
    • DOI 10.1006/jcrs.2001.0433
    • CM Courtin JA Delcour 2002 Arabinoxylans and endoxylanases in wheat flour bread-making J Cereal Sci 35 225 243 10.1006/jcrs.2001.0433 1:CAS:528:DC%2BD38Xlsl2qtb8%3D (Pubitemid 34757820)
    • (2002) Journal of Cereal Science , vol.35 , Issue.3 , pp. 225-243
    • Courtin, C.M.1    Delcour, J.A.2
  • 11
    • 33645943709 scopus 로고    scopus 로고
    • Oligosaccharide binding in family 8 glycosidases: Crystal structures of active-site mutants of the β-1, 4-xylanase pXyl from Pseudoaltermonas haloplanktis TAH3a in complex with substrate and product
    • 10.1021/bi052193e
    • D De Vos T Collins W Nerinckx SN Savvides M Claeyssens C Gerday G Feller J Van Beeumen 2006 Oligosaccharide binding in family 8 glycosidases: Crystal structures of active-site mutants of the β-1, 4-xylanase pXyl from Pseudoaltermonas haloplanktis TAH3a in complex with substrate and product Biochemistry 45 4797 4807 10.1021/bi052193e
    • (2006) Biochemistry , vol.45 , pp. 4797-4807
    • De Vos, D.1    Collins, T.2    Nerinckx, W.3    Savvides, S.N.4    Claeyssens, M.5    Gerday, C.6    Feller, G.7    Van Beeumen, J.8
  • 13
    • 0347895063 scopus 로고    scopus 로고
    • Enzymatic synthesis of β-xylanase substrates: Transglycosylation reactions of the β-xylosidase from Aspergillus sp.
    • DOI 10.1016/S0008-6215(02)00467-6, PII S0008621502004676
    • EV Eneyskaya H Brumer LV Backinowsky DR Ivanen AA Kulminskaya KA Shabalin KN Neustroev 2003 Enzymatic synthesis of β-xylanase substrates: transglycosylation reactions of the β-xylosidase from Aspergillus sp Carbohydr Res 338 313 325 10.1016/S0008-6215(02)00467-6 1:CAS:528: DC%2BD3sXmslektA%3D%3D (Pubitemid 36135895)
    • (2003) Carbohydrate Research , vol.338 , Issue.4 , pp. 313-325
    • Eneyskaya, E.V.1    Brumer III, H.2    Backinowsky, L.V.3    Ivanen, D.R.4    Kulminskaya, A.A.5    Shabalin, K.A.6    Neustroev, K.N.7
  • 14
    • 3042825332 scopus 로고    scopus 로고
    • Substrate selectivity and inhibitor sensitivity affect xylanase functionality in wheat flour gluten-starch separation
    • DOI 10.1016/j.jcs.2004.04.002, PII S0733521004000244
    • SA Frederix CA Courtin JA Delcour 2004 Substrate selectivity and inhibitor sensitivity affect xylanase functionality in wheat flour gluten-starch separation J Cereal Sci 40 41 49 10.1016/j.jcs.2004.04.002 1:CAS:528: DC%2BD2cXlt1emtLw%3D (Pubitemid 38851963)
    • (2004) Journal of Cereal Science , vol.40 , Issue.1 , pp. 41-49
    • Frederix, S.A.1    Courtin, C.M.2    Delcour, J.A.3
  • 15
    • 11144239263 scopus 로고    scopus 로고
    • Water-extractable and water-unextractable arabinoxylans affect gluten agglomeration behavior during wheat flour gluten-starch separation
    • 10.1021/jf049041v 1:CAS:528:DC%2BD2cXhtVCntLrK
    • SA Frederix KE Van Hoeymissen CM Courtin JA Delcour 2004 Water-extractable and water-unextractable arabinoxylans affect gluten agglomeration behavior during wheat flour gluten-starch separation J Agric Food Chem 52 7950 7956 10.1021/jf049041v 1:CAS:528:DC%2BD2cXhtVCntLrK
    • (2004) J Agric Food Chem , vol.52 , pp. 7950-7956
    • Frederix, S.A.1    Van Hoeymissen, K.E.2    Courtin, C.M.3    Delcour, J.A.4
  • 16
    • 20444504291 scopus 로고    scopus 로고
    • Structural basis for the specificity of the reducing end xylose-releasing exo-oligoxylanase from Bacillus halodurans C-125
    • DOI 10.1074/jbc.M413693200
    • S Fushinobu M Hidaka Y Honda T Wakagi H Shoun M Kitaoka 2005 Structural basis for the specificity of the reducing end xylose-releasing exo-oligoxylanase from Bacillus halodurans C-125 J Biol Chem 280 17180 17186 10.1074/jbc. M413693200 1:CAS:528:DC%2BD2MXjsFOgtb4%3D (Pubitemid 41389184)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.17 , pp. 17180-17186
    • Fushinobu, S.1    Hidaka, M.2    Honda, Y.3    Wakagi, T.4    Shoun, H.5    Kitaoka, M.6
  • 17
    • 11244279648 scopus 로고    scopus 로고
    • A family 8 glycoside hydrolase from Bacillus halodurans C-125 (BH2105) is a reducing end xylose-releasing exo-oligoxylanase
    • DOI 10.1074/jbc.M409832200
    • Y Honda M Kitaoka 2004 A family 8 glycoside hydrolase from Bacillus halodurans C-125 (BH2105) is a reducing end xylose-releasing exo-oligoxylanase J Biol Chem 279 55097 55103 10.1074/jbc.M409832200 1:CAS:528:DC%2BD2cXhtFeis7%2FM (Pubitemid 40066502)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.53 , pp. 55097-55103
    • Honda, Y.1    Kitaoka, M.2
  • 18
    • 42349097375 scopus 로고    scopus 로고
    • Flexible biorefinery for producing fermentation sugars, lignin and pulp from corn stover
    • 10.1007/s10295-008-0322-0 1:CAS:528:DC%2BD1cXks1Gns7g%3D
    • KL Kadam CY Chin LW Brown 2008 Flexible biorefinery for producing fermentation sugars, lignin and pulp from corn stover J Ind Microbiol Biotechnol 35 331 341 10.1007/s10295-008-0322-0 1:CAS:528:DC%2BD1cXks1Gns7g%3D
    • (2008) J Ind Microbiol Biotechnol , vol.35 , pp. 331-341
    • Kadam, K.L.1    Chin, C.Y.2    Brown, L.W.3
  • 19
    • 49249091688 scopus 로고    scopus 로고
    • Enzyme processes for pulp and paper: A review of recent developments
    • 10.1021/bk-2003-0845.ch012 1:CAS:528:DC%2BD3sXksFeks7k%3D
    • WR Kenealy TW Jeffries 2003 Enzyme processes for pulp and paper: a review of recent developments Wood Deterioration and Preservation 845 210 239 10.1021/bk-2003-0845.ch012 1:CAS:528:DC%2BD3sXksFeks7k%3D
    • (2003) Wood Deterioration and Preservation , vol.845 , pp. 210-239
    • Kenealy, W.R.1    Jeffries, T.W.2
  • 20
    • 34548209675 scopus 로고    scopus 로고
    • Recombinant expression and characterization of a reducing-end xylose-releasing exo-oligoxylanase from Bifidobacterium adolescentis
    • DOI 10.1128/AEM.00722-07
    • S Lagaert S Van Campenhout A Pollet TM Bourgois JA Delcour CM Courtin G Volckaert 2007 Recombinant expression and characterization of a reducing-end xylose-releasing exo-oligoxylanase from Bifidobacterium adolescentis Appl Environ Microbiol 73 5374 5377 10.1128/AEM.00722-07 1:CAS:528: DC%2BD2sXpsleqtL0%3D (Pubitemid 47326672)
    • (2007) Applied and Environmental Microbiology , vol.73 , Issue.16 , pp. 5374-5377
    • Lagaert, S.1    Van Campenhout, S.2    Pollet, A.3    Bourgois, T.M.4    Delcour, J.A.5    Courtin, C.M.6    Volckaert, G.7
  • 22
    • 33748290144 scopus 로고    scopus 로고
    • Cloning and characterization of a cold-active xylanase enzyme from an environmental DNA library
    • DOI 10.1007/s00792-005-0499-3
    • CC Lee RE Kibblewhite-Accinelli K Wagschal GH Robertson DWS Wong 2006 Cloning and characterization of a cold-active xylanase enzyme from an environmental DNA library Extremophiles 10 295 300 10.1007/s00792-005-0499-3 1:CAS:528:DC%2BD28XovVWitr8%3D (Pubitemid 44325659)
    • (2006) Extremophiles , vol.10 , Issue.4 , pp. 295-300
    • Lee, C.C.1    Kibblewhite-Accinelli, R.E.2    Wagschal, K.3    Robertson, G.H.4    Wong, D.W.S.5
  • 23
    • 4644319847 scopus 로고    scopus 로고
    • Control of arabinoxylan solubilization and hydrolysis in mashing
    • DOI 10.1016/j.foodchem.2004.03.031, PII S0308814604002729
    • Y Li J Lu GX Gu 2005 Control of arabinoxylan solubilization and hydrolysis in mashing Food Chem 90 101 108 10.1016/j.foodchem.2004.03.031 1:CAS:528:DC%2BD2cXotV2jtb4%3D (Pubitemid 39298791)
    • (2005) Food Chemistry , vol.90 , Issue.1-2 , pp. 101-108
    • Li, Y.1    Lu, J.2    Gu, G.3
  • 25
    • 58849126109 scopus 로고    scopus 로고
    • Fusarium graminearum xylanases show different functional stabilities, substrate specificities and inhibition sensitivities
    • 10.1016/j.enzmictec.2008.12.005 1:CAS:528:DC%2BD1MXhtlOgsr0%3D
    • A Pollet T Beliën K Fierens JA Delcour CM Courtin 2009 Fusarium graminearum xylanases show different functional stabilities, substrate specificities and inhibition sensitivities Enzyme Microb Technol 44 189 195 10.1016/j.enzmictec.2008.12.005 1:CAS:528:DC%2BD1MXhtlOgsr0%3D
    • (2009) Enzyme Microb Technol , vol.44 , pp. 189-195
    • Pollet, A.1    Beliën, T.2    Fierens, K.3    Delcour, J.A.4    Courtin, C.M.5
  • 26
    • 70349443443 scopus 로고    scopus 로고
    • Crystallographic and activity-based evidence for thumb flexibility and its relevance in glycoside hydrolase family 11 xylanases
    • 10.1002/prot.22445 1:CAS:528:DC%2BD1MXhtV2lt7fJ
    • A Pollet E Vandermarliere J Lammertyn SV Strelkov JA Delcour CM Courtin 2009 Crystallographic and activity-based evidence for thumb flexibility and its relevance in glycoside hydrolase family 11 xylanases Proteins Struct Funct Bioinformat 77 395 403 10.1002/prot.22445 1:CAS:528:DC%2BD1MXhtV2lt7fJ
    • (2009) Proteins Struct Funct Bioinformat , vol.77 , pp. 395-403
    • Pollet, A.1    Vandermarliere, E.2    Lammertyn, J.3    Strelkov, S.V.4    Delcour, J.A.5    Courtin, C.M.6
  • 27
    • 77955554477 scopus 로고    scopus 로고
    • Structural determinants of the substrate specificities of xylanases from different glycoside hydrolase families
    • 10.3109/07388551003645599
    • A Pollet JA Delcour CM Courtin 2010 Structural determinants of the substrate specificities of xylanases from different glycoside hydrolase families Crit Rev Biotechnol 10.3109/07388551003645599
    • (2010) Crit Rev Biotechnol
    • Pollet, A.1    Delcour, J.A.2    Courtin, C.M.3
  • 28
    • 76849112864 scopus 로고    scopus 로고
    • Mutagenesis and subsite mapping underpin the importance for substrate specificity of the aglycon subsites of glycoside hydrolase family 11 xylanases
    • 10.1016/j.bbapap.2010.01.009 1:CAS:528:DC%2BC3cXis1Sjtr8%3D
    • A Pollet S Lagaert E Eneyskaya A Kulminskaya JA Delcour CM Courtin 2010 Mutagenesis and subsite mapping underpin the importance for substrate specificity of the aglycon subsites of glycoside hydrolase family 11 xylanases Biochim Biophys Acta Proteins Proteomics 1804 977 985 10.1016/j.bbapap.2010.01. 009 1:CAS:528:DC%2BC3cXis1Sjtr8%3D
    • (2010) Biochim Biophys Acta Proteins Proteomics , vol.1804 , pp. 977-985
    • Pollet, A.1    Lagaert, S.2    Eneyskaya, E.3    Kulminskaya, A.4    Delcour, J.A.5    Courtin, C.M.6
  • 30
    • 0037623814 scopus 로고    scopus 로고
    • Hemicellulose bioconversion
    • DOI 10.1007/s10295-003-0049-x
    • BC Saha 2003 Hemicellulose bioconversion J Ind Microbiol Biotechnol 30 279 291 10.1007/s10295-003-0049-x 1:CAS:528:DC%2BD3sXltFCntb4%3D (Pubitemid 36873792)
    • (2003) Journal of Industrial Microbiology and Biotechnology , vol.30 , Issue.5 , pp. 279-291
    • Saha, B.C.1
  • 31
    • 0027136282 scopus 로고
    • Comparative protein modelling by satisfaction of spatial restraints
    • DOI 10.1006/jmbi.1993.1626
    • A Sali TL Blundell 1993 Comparative protein modelling by satisfaction of spatial restraints J Mol Biol 234 779 815 10.1006/jmbi.1993.1626 1:CAS:528:DyaK2cXnt1ylug%3D%3D (Pubitemid 24007801)
    • (1993) Journal of Molecular Biology , vol.234 , Issue.3 , pp. 779-815
    • Sali, A.1    Blundell, T.L.2
  • 32
    • 33747240753 scopus 로고    scopus 로고
    • Large-scale production and characterisation of wheat bran arabinoxylooligosaccharides
    • 10.1002/jsfa.2470 1:CAS:528:DC%2BD28Xoslaitb0%3D
    • K Swennen CM Courtin GCJE Lindemans JA Delcour 2006 Large-scale production and characterisation of wheat bran arabinoxylooligosaccharides J Sci Food Agric 86 1722 1731 10.1002/jsfa.2470 1:CAS:528:DC%2BD28Xoslaitb0%3D
    • (2006) J Sci Food Agric , vol.86 , pp. 1722-1731
    • Swennen, K.1    Courtin, C.M.2    Gcje, L.3    Delcour, J.A.4
  • 34
    • 8844269568 scopus 로고    scopus 로고
    • The combined use of hull-less barley flour and xylanase as a strategy for wheat/hull-less barley flour breads with increased arabinoxylan and (1→3,1→4)-β-D-glucan levels
    • DOI 10.1016/j.jcs.2004.08.008, PII S0733521004000931
    • I Trogh CM Courtin AAM Andersson P Aman JF Sorensen JA Delcour 2004 The combined use of hull-less barley flour and xylanase as a strategy for wheat/hull-less barley flour breads with increased arabinoxylan and (1-3, 1-4)-β-d-glucan levels J Cereal Sci 40 257 267 10.1016/j.jcs.2004.08.008 1:CAS:528:DC%2BD2cXhtVSnsb7M (Pubitemid 39527158)
    • (2004) Journal of Cereal Science , vol.40 , Issue.3 , pp. 257-267
    • Trogh, I.1    Courtin, C.M.2    Andersson, A.A.M.3    Aman, P.4    Sorensen, J.F.5    Delcour, J.A.6
  • 35
    • 4544241403 scopus 로고    scopus 로고
    • Isolation and characterization of water-extractable arabinoxylan from hull-less barley flours
    • 10.1094/CCHEM.2004.81.5.576 1:CAS:528:DC%2BD2cXns1yhsL4%3D
    • I Trogh CM Courtin JA Delcour 2004 Isolation and characterization of water-extractable arabinoxylan from hull-less barley flours Cereal Chem 81 576 581 10.1094/CCHEM.2004.81.5.576 1:CAS:528:DC%2BD2cXns1yhsL4%3D
    • (2004) Cereal Chem , vol.81 , pp. 576-581
    • Trogh, I.1    Courtin, C.M.2    Delcour, J.A.3
  • 38
    • 15544368918 scopus 로고    scopus 로고
    • Cloning and characterization of arabinoxylan arabinofuranohydrolase-D3 (AXHd3) from Bifidobacterium adolescentis DSM20083
    • DOI 10.1007/s00253-004-1850-9
    • LAM van den Broek RM Lloyd G Beldman JC Verdoes BV McCleary AGJ Voragen 2005 Cloning and characterization of arabinoxylan arabinofuranohydrolase-D3 (AXHd3) from Bifidobacterium adolescentis DSM20083 Appl Microbiol Biotechnol 67 641 647 10.1007/s00253-004-1850-9 (Pubitemid 40898082)
    • (2005) Applied Microbiology and Biotechnology , vol.67 , Issue.5 , pp. 641-647
    • Van Den Broek, L.A.M.1    Lloyd, R.M.2    Beldman, G.3    Verdoes, J.C.4    McCleary, B.V.5    Voragen, A.G.J.6
  • 39
    • 0037470085 scopus 로고    scopus 로고
    • The structure of a cold-adapted family 8 xylanase at 1.3 A resolution. Structural adaptations to cold and investigation of the active site
    • DOI 10.1074/jbc.M206862200
    • F Van Petegem T Collins MA Meuwis C Gerday G Feller J Van Beeumen 2003 The structure of a cold-adapted family 8 xylanase at 1.3Å-Structural adaptations to cold and investigation of the active site J Biol Chem 278 7531 7539 10.1074/jbc.M206862200 (Pubitemid 36800760)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.9 , pp. 7531-7539
    • Van Petegem, F.1    Collins, T.2    Meuwis, M.-A.3    Gerday, C.4    Feller, G.5    Van Beeumen, J.6
  • 40
    • 0034950355 scopus 로고    scopus 로고
    • Xylooligosaccharides: Manufacture and applications
    • 10.1016/S0924-2244(01)00031-0 1:CAS:528:DC%2BD3MXkvVegt70%3D
    • MJ Vazquez JL Alonso H Dominguez JC Parajo 2000 Xylooligosaccharides: manufacture and applications Trends Food Sci Technol 11 387 393 10.1016/S0924-2244(01)00031-0 1:CAS:528:DC%2BD3MXkvVegt70%3D
    • (2000) Trends Food Sci Technol , vol.11 , pp. 387-393
    • Vazquez, M.J.1    Alonso, J.L.2    Dominguez, H.3    Parajo, J.C.4
  • 41
    • 0031855120 scopus 로고    scopus 로고
    • Molecular cloning of a Bacillus sp. KK-1 xylanase gene and characterization of the gene product
    • 1:CAS:528:DyaK1cXktlCisbs%3D
    • KH Yoon HN Yun KH Jung 1998 Molecular cloning of a Bacillus sp. KK-1 xylanase gene and characterization of the gene product Biochem Mol Biol Int 45 337 347 1:CAS:528:DyaK1cXktlCisbs%3D
    • (1998) Biochem Mol Biol Int , vol.45 , pp. 337-347
    • Yoon, K.H.1    Yun, H.N.2    Jung, K.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.