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Volumn 30, Issue 10, 2010, Pages 1341-1348

Strontium ranelate and alendronate have differing effects on distal tibia bone microstructure in women with osteoporosis

Author keywords

Biochemical markers; Bone mineral density; Cortical bone; Microstructure; Trabecular bone

Indexed keywords

ALENDRONIC ACID; CALCIUM; PLACEBO; STRONTIUM RANELATE; VITAMIN D; BONE DENSITY CONSERVATION AGENT; ORGANOMETALLIC COMPOUND; THIOPHENE DERIVATIVE;

EID: 77955559627     PISSN: 01728172     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00296-010-1542-y     Document Type: Article
Times cited : (78)

References (29)
  • 1
    • 0020509916 scopus 로고
    • Relationships between surface, volume and thickness of iliac trabecular bone in aging and in osteoporosis. Implications for the microanatomic and cellular mechanisms of bone loss
    • 10.1172/JCI111096 1:STN:280:DyaL2c%2FjtlWlug%3D%3D 6630513
    • A Parfitt CH Mathews AR Villanueva M Kleerekoper B Frame DS Rao 1983 Relationships between surface, volume and thickness of iliac trabecular bone in aging and in osteoporosis. Implications for the microanatomic and cellular mechanisms of bone loss J Clin Invest 72 1396 1409 10.1172/JCI111096 1:STN:280:DyaL2c%2FjtlWlug%3D%3D 6630513
    • (1983) J Clin Invest , vol.72 , pp. 1396-1409
    • Parfitt, A.1    Mathews, C.H.2    Villanueva, A.R.3    Kleerekoper, M.4    Frame, B.5    Rao, D.S.6
  • 2
    • 33646889773 scopus 로고    scopus 로고
    • Bone quality-the material and structural basis of bone strength and fragility
    • 10.1056/NEJMra053077 1:CAS:528:DC%2BD28XkvVShsbw%3D 16723616
    • E Seeman PD Delmas 2006 Bone quality-the material and structural basis of bone strength and fragility N Engl J Med 354 21 2250 2261 10.1056/NEJMra053077 1:CAS:528:DC%2BD28XkvVShsbw%3D 16723616
    • (2006) N Engl J Med , vol.354 , Issue.21 , pp. 2250-2261
    • Seeman, E.1    Delmas, P.D.2
  • 3
    • 0037042498 scopus 로고    scopus 로고
    • Treatment of postmenopausal osteoporosis
    • DOI 10.1016/S0140-6736(02)08827-X
    • PD Delmas 2002 Treatment of postmenopausal osteoporosis Lancet 359 9322 2018 2026 10.1016/S0140-6736(02)08827-X 1:CAS:528:DC%2BD38XksFKkt7g%3D 12076571 (Pubitemid 34663722)
    • (2002) Lancet , vol.359 , Issue.9322 , pp. 2018-2026
    • Delmas, P.D.1
  • 4
    • 27944449749 scopus 로고    scopus 로고
    • In vivo assessment of trabecular bone microarchitecture by high-resolution peripheral quantitative computed tomography
    • DOI 10.1210/jc.2005-1258
    • S Boutroy M Bouxsein F Munoz P Delmas 2005 In vivo assessment of trabecular bone microarchitecture by high resolution peripheral quantitative computed tomography J Clin Endocrinol Metab 90 6508 6515 10.1210/jc.2005-1258 1:CAS:528:DC%2BD2MXhtlaltLzI 16189253 (Pubitemid 41759306)
    • (2005) Journal of Clinical Endocrinology and Metabolism , vol.90 , Issue.12 , pp. 6508-6515
    • Boutroy, S.1    Bouxsein, M.L.2    Munoz, F.3    Delmas, P.D.4
  • 5
    • 0031460813 scopus 로고    scopus 로고
    • Ridge number density: A new parameter for in vivo bone structure analysis
    • DOI 10.1016/S8756-3282(97)00205-6, PII S8756328297002056
    • A Laib T Hildebrand HJ Haüselmann P Rüegsegger 1997 Ridge number density: a new parameter for in vivo bone structure analysis Bone 21 6 541 546 10.1016/S8756-3282(97)00205-6 1:STN:280:DyaK1c%2FptVWisg%3D%3D 9430245 (Pubitemid 28029698)
    • (1997) Bone , vol.21 , Issue.6 , pp. 541-546
    • Laib, A.1
  • 6
    • 0344301894 scopus 로고    scopus 로고
    • Calibration of trabecular bone structure measurements of in vivo three-dimensional peripheral quantitative computed tomography with 28-μm-resolution microcomputed tomography
    • DOI 10.1016/S8756-3282(98)00159-8, PII S8756328298001598
    • A Laib P Rüegsegger 1999 Calibration of trabecular bone structure measurements of in vivo three-dimensional peripheral quantitative computed tomography with 28-microm-resolution microcomputed tomography Bone 24 1 35 39 10.1016/S8756-3282(98)00159-8 1:STN:280:DyaK1M7htlyhsg%3D%3D 9916782 (Pubitemid 28546704)
    • (1999) Bone , vol.24 , Issue.1 , pp. 35-39
    • Laib, A.1    Ruegsegger, P.2
  • 7
    • 34547561381 scopus 로고    scopus 로고
    • Is a change in bone mineral density a sensitive and specific surrogate of anti-fracture efficacy?
    • DOI 10.1016/j.bone.2007.06.010, PII S875632820700508X
    • E Seeman 2007 Is a change in bone mineral density a sensitive and specific surrogate of anti-fracture efficacy? Bone 41 3 308 317 10.1016/j.bone.2007.06.010 1:STN:280:DC%2BD2svntlaqtw%3D%3D 17644058 (Pubitemid 47199158)
    • (2007) Bone , vol.41 , Issue.3 , pp. 308-317
    • Seeman, E.1
  • 8
    • 0028851590 scopus 로고
    • Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis, The Alendronate Phase III Osteoporosis Treatment Study Group
    • 10.1056/NEJM199511303332201 1:CAS:528:DyaK28XkslehtA%3D%3D 7477143
    • UA Liberman SR Weiss J Bröll, et al. 1995 Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis, The Alendronate Phase III Osteoporosis Treatment Study Group N Engl J Med 333 22 1437 1443 10.1056/NEJM199511303332201 1:CAS:528: DyaK28XkslehtA%3D%3D 7477143
    • (1995) N Engl J Med , vol.333 , Issue.22 , pp. 1437-1443
    • Liberman, U.A.1    Weiss, S.R.2    Bröll, J.3
  • 9
    • 56349158692 scopus 로고    scopus 로고
    • Bisphosphonates: How do they work?
    • 10.1016/j.beem.2008.07.001 1:CAS:528:DC%2BD1cXhsVWmsbnJ
    • SE Papapoulos 2008 Bisphosphonates: how do they work? Best Pract Res Clin Endocrinal Metab 22 5 831 847 10.1016/j.beem.2008.07.001 1:CAS:528: DC%2BD1cXhsVWmsbnJ
    • (2008) Best Pract Res Clin Endocrinal Metab , vol.22 , Issue.5 , pp. 831-847
    • Papapoulos, S.E.1
  • 10
    • 43049109229 scopus 로고    scopus 로고
    • Mechanisms of action of bisphosphonates: Similarities and differences and their potential influence on clinical efficacy
    • 10.1007/s00198-007-0540-8
    • RG Russel N Watts F Ebetino M Rogers 2008 Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy Osteoporos Int 19 733 759 10.1007/s00198-007-0540-8
    • (2008) Osteoporos Int , vol.19 , pp. 733-759
    • Russel, R.G.1    Watts, N.2    Ebetino, F.3    Rogers, M.4
  • 11
    • 0030868816 scopus 로고    scopus 로고
    • Histomorphometric assessment of the long-term effects of alendronate on bone quality and remodelling in patients with osteoporosis
    • 10.1172/JCI119668 1:CAS:528:DyaK2sXmt1Cqsb8%3D 9294113
    • PM Chavassieux ME Arlot C Reda L Wei J Yates PJ Meunier 1997 Histomorphometric assessment of the long-term effects of alendronate on bone quality and remodelling in patients with osteoporosis J Clin Invest 100 1475 1480 10.1172/JCI119668 1:CAS:528:DyaK2sXmt1Cqsb8%3D 9294113
    • (1997) J Clin Invest , vol.100 , pp. 1475-1480
    • Chavassieux, P.M.1    Arlot, M.E.2    Reda, C.3    Wei, L.4    Yates, J.5    Meunier, P.J.6
  • 14
    • 0027139913 scopus 로고
    • The effects of 2-year treatment with the aminobisphosphonate alendronate on bone metabolism, bone histomorphometry, and bone strength in ovariectomized nonhuman primates
    • 10.1172/JCI116872 1:CAS:528:DyaK2cXmvFGmuw%3D%3D 8254015
    • R Balena BC Toolan M Shea A Markatos ER Myers SC Lee EE Opas JG Seedor H Klein D Frankenfield, et al. 1993 The effects of 2-year treatment with the aminobisphosphonate alendronate on bone metabolism, bone histomorphometry, and bone strength in ovariectomized nonhuman primates J Clin Invest 92 6 2577 2586 10.1172/JCI116872 1:CAS:528:DyaK2cXmvFGmuw%3D%3D 8254015
    • (1993) J Clin Invest , vol.92 , Issue.6 , pp. 2577-2586
    • Balena, R.1    Toolan, B.C.2    Shea, M.3    Markatos, A.4    Myers, E.R.5    Lee, S.C.6    Opas, E.E.7    Seedor, J.G.8    Klein, H.9    Frankenfield, D.10
  • 16
    • 70350304534 scopus 로고    scopus 로고
    • Osteoblasts play key roles in the mechanisms of action of strontium ranelate
    • 10.1111/j.1476-5381.2009.00305.x 1:CAS:528:DC%2BD1MXhtVelt7fN
    • TC Brennan MS Rybchyn W Green S Atwa AD Conigrave RS Mason 2009 Osteoblasts play key roles in the mechanisms of action of strontium ranelate Brit L Pharmacol 157 7 1291 1300 10.1111/j.1476-5381.2009.00305.x 1:CAS:528:DC%2BD1MXhtVelt7fN
    • (2009) Brit L Pharmacol , vol.157 , Issue.7 , pp. 1291-1300
    • Brennan, T.C.1    Rybchyn, M.S.2    Green, W.3    Atwa, S.4    Conigrave, A.D.5    Mason, R.S.6
  • 17
    • 37349123534 scopus 로고    scopus 로고
    • Dual effect of strontium ranelate: Stimulation of osteoblast differentiation and inhibition of osteoclast formation and resorption in vitro
    • DOI 10.1016/j.bone.2007.08.043, PII S8756328207006667
    • E Bonnelye A Chabadel F Saltel P Jurdic 2008 Dual Effect of strontium ranelate: stimulation of osteoblast differentiation and inhibition of osteoclast formation and resorption in vitro Bone 42 129 138 10.1016/j.bone.2007.08.043 1:CAS:528:DC%2BD2sXhsVOrtr3E 17945546 (Pubitemid 350297175)
    • (2008) Bone , vol.42 , Issue.1 , pp. 129-138
    • Bonnelye, E.1    Chabadel, A.2    Saltel, F.3    Jurdic, P.4
  • 18
    • 34250870142 scopus 로고    scopus 로고
    • The calcium-sensing receptor (CaR) is involved in strontium ranelate-induced osteoblast proliferation
    • DOI 10.1016/j.bcp.2007.04.020, PII S0006295207002602
    • N Chattopadhyay SJ Quinn O Kifor C Ye EM Brown 2007 The calcium-sensing receptor (CaR) is involved in strontium ranelate-induced osteoblast proliferation Biochem Pharmacol 74 3 438 447 10.1016/j.bcp.2007.04.020 1:CAS:528:DC%2BD2sXntFamurs%3D 17531955 (Pubitemid 46970843)
    • (2007) Biochemical Pharmacology , vol.74 , Issue.3 , pp. 438-447
    • Chattopadhyay, N.1    Quinn, S.J.2    Kifor, O.3    Ye, C.4    Brown, E.M.5
  • 19
    • 62149087855 scopus 로고    scopus 로고
    • Strontium ranelate treatment of human primary osteoblasts promotes an osteocyte-like phenotype while eliciting an osteoprotegerin response
    • 10.1007/s00198-008-0728-6 1:CAS:528:DC%2BD1MXis1Glurs%3D 18763010
    • GJ Atkins KJ Welldon P Halbout DM Findlay 2009 Strontium ranelate treatment of human primary osteoblasts promotes an osteocyte-like phenotype while eliciting an osteoprotegerin response Osteoporos Int 20 653 664 10.1007/s00198-008-0728-6 1:CAS:528:DC%2BD1MXis1Glurs%3D 18763010
    • (2009) Osteoporos Int , vol.20 , pp. 653-664
    • Atkins, G.J.1    Welldon, K.J.2    Halbout, P.3    Findlay, D.M.4
  • 20
    • 67650476919 scopus 로고    scopus 로고
    • Strontium ranelate improves bone strength in ovariectomized rat by positively influencing bone resistance determinants
    • 10.1007/s00198-008-0815-8 1:CAS:528:DC%2BD1MXotlyhurg%3D 19096745
    • SD Bain C Jerome V Shen I Dupin-Roger P Ammann 2009 Strontium ranelate improves bone strength in ovariectomized rat by positively influencing bone resistance determinants Osteoporos Int 20 8 1417 1428 10.1007/s00198-008-0815-8 1:CAS:528:DC%2BD1MXotlyhurg%3D 19096745
    • (2009) Osteoporos Int , vol.20 , Issue.8 , pp. 1417-1428
    • Bain, S.D.1    Jerome, C.2    Shen, V.3    Dupin-Roger, I.4    Ammann, P.5
  • 24
    • 0032463334 scopus 로고    scopus 로고
    • In vivo resolution 3D-QCT of the human forearm
    • 1:STN:280:DyaK1M7pvFSgtw%3D%3D
    • A Laib HJ Hauselmann P Ruegsegger 1998 In vivo resolution 3D-QCT of the human forearm Thechnol Health Care 6 329 337 1:STN:280:DyaK1M7pvFSgtw%3D%3D
    • (1998) Thechnol Health Care , vol.6 , pp. 329-337
    • Laib, A.1    Hauselmann, H.J.2    Ruegsegger, P.3
  • 25
    • 77950940515 scopus 로고    scopus 로고
    • In osteoporotic women treated with strontium ranelate, strontium is located in bone formed during treatment with a maintained degree of mineralization
    • Boivin G, Farlay D, Khebbab MT, Jaurand X, Delmas PD, Meunier PJ (2009) In osteoporotic women treated with strontium ranelate, strontium is located in bone formed during treatment with a maintained degree of mineralization. Osteoporos Int 2010 Apr; 21(4):667-677
    • (2009) Osteoporos Int 2010 Apr , vol.21 , Issue.4 , pp. 667-677
    • Boivin, G.1    Farlay, D.2    Khebbab, M.T.3    Jaurand, X.4    Delmas, P.D.5    Meunier, P.J.6
  • 26
    • 0141834677 scopus 로고    scopus 로고
    • The mineralization of bone tissue: A forgotten dimension in osteoporosis research
    • 12730799
    • G Boivin PJ Meunier 2003 The mineralization of bone tissue: a forgotten dimension in osteoporosis research Osteoporos Int 14 Suppl 3 S19 S24 12730799
    • (2003) Osteoporos Int , vol.14 , Issue.SUPPL. 3
    • Boivin, G.1    Meunier, P.J.2
  • 27
    • 0033755981 scopus 로고    scopus 로고
    • Alendronate increases bone strength by increasing the mean degree of mineralization of bone tissue in osteoporotic women
    • 10.1016/S8756-3282(00)00376-8 1:CAS:528:DC%2BD3cXosFygtL8%3D 11062357
    • G Boivin P Chavassieux AC Santora 2000 Alendronate increases bone strength by increasing the mean degree of mineralization of bone tissue in osteoporotic women Bone 27 687 694 10.1016/S8756-3282(00)00376-8 1:CAS:528:DC%2BD3cXosFygtL8%3D 11062357
    • (2000) Bone , vol.27 , pp. 687-694
    • Boivin, G.1    Chavassieux, P.2    Santora, A.C.3
  • 28
    • 35948972789 scopus 로고    scopus 로고
    • The effects of geometric and threshold definitions on cortical bone metrics assessed by in vivo high-resolution peripheral quantitative computed tomography
    • DOI 10.1007/s00223-007-9076-3
    • KA Davis AJ Burghardt TM Link S Majumdar 2007 The effects of geometric and threshold definitions on cortical bone metrics assessed by in vivo high-resolution peripheral quantitative computed tomography Calcif Tissue Int 81 364 371 10.1007/s00223-007-9076-3 1:CAS:528:DC%2BD2sXht1Oks77K 17952361 (Pubitemid 350077204)
    • (2007) Calcified Tissue International , vol.81 , Issue.5 , pp. 364-371
    • Davis, K.A.1    Burghardt, A.J.2    Link, T.M.3    Majumdar, S.4
  • 29
    • 0028586042 scopus 로고
    • Comparison of new biochemical markers of bone turnover in late postmenopausal osteoporotic women in response to alendronate treatment
    • 10.1210/jc.79.6.1693 1:CAS:528:DyaK2MXislWiuro%3D 7989477
    • P Garnero W Shih E Gineyts D Karpf P Delmas 1994 Comparison of new biochemical markers of bone turnover in late postmenopausal osteoporotic women in response to alendronate treatment J Clin Endocrinol Metab 79 6 1693 1700 10.1210/jc.79.6.1693 1:CAS:528:DyaK2MXislWiuro%3D 7989477
    • (1994) J Clin Endocrinol Metab , vol.79 , Issue.6 , pp. 1693-1700
    • Garnero, P.1    Shih, W.2    Gineyts, E.3    Karpf, D.4    Delmas, P.5


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