Synthesis and evaluation of graveoline and graveolinine derivatives with potent anti-angiogenesis activities

European Journal of Medicinal Chemistry

Volumn 45, Issue 9, 2010, Pages 3895-3903

  An, Zeng Yun ^a   Yan, Yi Yong ^a   Peng, Dan ^a   Ou, Tian Miao ^a   Tan, Jia Heng ^a   Huang, Shi Liang ^a   An, Lin Kun ^a   Gu, Lian Quan ^a   Huang, Zhi Shu ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Anti angiogenesis; Graveoline derivatives; Graveolinine derivatives; Synthesis

Indexed keywords

2 (4 METHOXYPHENYL)QUINOLIN 4 (1H) ONE; 2 (4 METHOXYPHENYL)QUINOLIN 4 YLAMINO)ETHANOL; 2 [2 (4 METHOXYPHENYL)QUINOLIN 4 YLAMINO]ETHANOL; 3 [2 (4 METHOXYPHENYL)QUINOLIN 4 YLAMINO]PROPAN 1 OL; 4 CHLORO 2 (4 METHOXYPHENYL)QUINOLINE; 4 CHLORO 2 (4 METHYLPHENYL)QUINOLINE; 4 METHOXY 2 (4 METHYLPHENYL)QUINOLINE; ANGIOGENESIS INHIBITOR; GRAVEOLINE DERIVATIVE; GRAVEOLININE DERIVATIVE; N (3 MORPHOLINOPROPYL) 2 (4 METHYLPHENYL)QUINOLIN 4 AMINE; N (4 METHOXYPHENYL) 2 (4 METHYLPHENYL)QUINOLIN 4 AMINE; UNCLASSIFIED DRUG;

ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOASSAY; CELL ADHESION; CELL MIGRATION; CHICK EMBRYO; CHORIOALLANTOIS; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG INHIBITION; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; EMBRYO; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; NONHUMAN; TUMOR CELL LINE; UMBILICAL VEIN;

ANGIOGENESIS INHIBITORS; ANIMALS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CHICK EMBRYO; CHORIOALLANTOIC MEMBRANE; ENDOTHELIAL CELLS; HUMANS; METHOXSALEN; QUINOLONES;

EID: 77955559076     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.05.043     Document Type: Article

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