A model system for testing gene vectors using murine tumor cells on thechorioallantoic membrane of the chick embryo

Genetics and Molecular Research

Volumn 1, Issue 2, 2002, Pages 167-175

  Dani, Sergio U ^a,b   Espindola, Rachel ^a  

^a AADM Gene Ther Ctr and Genon Ltd   (Brazil)

^b Genon Ltd   (Brazil)

Author keywords

Animal models; Cancer gene therapy; Chorioallantoic membrane; Gene vector screening

Indexed keywords

BETA GALACTOSIDASE; VIRUS VECTOR;

ANIMAL MODEL; ARTICLE; BACTERIAL GENE; CHICK EMBRYO; CHORIOALLANTOIS; CONTROLLED STUDY; COST BENEFIT ANALYSIS; EVALUATION; GENE VECTOR; GENETIC TRANSDUCTION; MEMBRANE MODEL; METASTASIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REPRODUCIBILITY; SURVIVAL RATE; TUMOR CELL; TUMOR GROWTH; ADENOVIRUS; ANIMAL; CELL CULTURE; CHORION; EXPERIMENTAL MELANOMA; FETUS MEMBRANE; GENETICS; HUMAN; PATHOLOGY;

ADENOVIRIDAE; ANIMALIA; BACTERIA (MICROORGANISMS); GALLUS GALLUS; MURINAE;

ADENOVIRIDAE; ALLANTOIS; ANIMALS; CHICK EMBRYO; CHORION; COST-BENEFIT ANALYSIS; GENETIC VECTORS; HUMANS; MELANOMA, EXPERIMENTAL; MICE; REPRODUCIBILITY OF RESULTS; TUMOR CELLS, CULTURED;

EID: 3242774638     PISSN: 16765680     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Armstrong, P.B., Quigley, J.P. and Sidebottom, E. (1982). Transepithelial invasion and intramesenchymal infiltration of the chick embryo chorioallantois by tumor cell lines. Cancer Res 42: 1826-1837.
2. Ausprunk, D.H., Knighton, D.R. and Folkman, J. (1974). Differentiation of vascular endothelium in chick chorioallantois: a structural and autoradiographic study. Dev. Biol. 38: 237-248.
3. Ausprunk, D.H., Knighton, D.R. and Folkman, J. (1975). Vascularization of normal and neoplastic tissues grafted to the chick chorioallantois. Role of host and preexisting graft blood vessels. Am. J. Pathol. 79: 597-628.
4. 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 79: 1157-1164.
5. Chambers, A.F., Shafir, R. and Ling, V. (1982). A model system for studying metastasis using the embryonic chick. Cancer Res. 42: 4018-4025.
6. Chambers, A.F., Schmidt, E.E., MacDonald, I.C., Morris, V.L. and Groom, A.C. (1992). Early steps in hematogenous metastasis of B16F1 melanoma cells in chick embryos studied by high-resolution intravital videomicroscopy. J. Natl. Cancer Inst. 84: 797-803.
7. Dani, S.U. (1999). The challenge of vector development in gene therapy. Braz. J. Med. Biol. Res. 32: 133-145.
8. Fidler, I.J. (1975). Biological behavior of malignant melanoma cells correlated with their survival in vivo. Cancer Res. 35: 218-244.
9. Gene Therapy Clinical Trials Update - February 1 (2001). The Journal of Gene Medicine, web site at http://www.wiley.co.uk/wileychi/genmed/clinical/ charts3.html
10. Graham, F.L. and Prevec, L. (1991). Manipulation of adenovirus vectors. In: Methods in Molecular Biology (Murray, E.J., ed.). Humana Press, Clifton, NJ, USA, 109-128.
11. Hamburger, V. (1960). A Manual of Experimental Embryology. University of Chicago Press, Chicago, IL, USA.
12. Karnofsky, D.A., Ridgway, L.P. and Patterson, P.A. (1952). Tumor transplantation to the chick embryo. Ann. N. Y. Acad. Sci. 55: 313-329.
13. Knighton, D., Ausprunk, D., Tapper, D. and Folkman, J. (1977). Avascular and vascular phase of tumor growth in the chick embryo. Br. J. Cancer 35: 347-356.
14. Leighton, J. (1964). Invasion and metastasis of heterologous tumors in the chick embryo. Prog. Exp. Tumor Res. 4: 98-125.
15. Norpoth, K. and Rauen, H.M. (1968). Tumorwachstum auf der Chorioallantoismembran im bebrüteten Hühnerei. Z. Krebsforsch. 71: 140-152.
16. Rotman, B. (1961). Measurement of activity of single molecules of β-D-galactosidase. Proc. Natl. Acad. Sci. USA 47: 1981-1991.
17. Stan, A.C., Radu, D.L., Casares, S., Bona, C.A. and Brumeanu, T.D. (1999). Antineoplastic efficacy of doxorubicin enzymatically assembled on galactose residues of a monoclonal antibody specific for the carcinoembryonic antigen. Cancer Res. 59: 115-121.
18. Stratford-Perricaudet, L.D., Makeh, I., Perricaudet, M. and Briand, P. (1992). Widespread long-term gene transfer to mouse skeletal muscles and heart. J. Clin. Invest. 90: 626-630.
19. Zwilling, E. (1959). A modified chorioallantoic grafting procedure. Transplant Bull. 6: 115-116.