Synthesis and activity of substituted 2-phenylquinolin-4-amines, antagonists of immunostimulatory CpG-oligodeoxynucleotides

Journal of Medicinal Chemistry

Volumn 46, Issue 7, 2003, Pages 1242-1249

  Strekowski, Lucjan ^a   Say, Martial ^a   Henary, Maged ^a   Ruiz, Patricia ^a   Manzel, Lori ^b   Macfarlane, Donald E ^b   Bojarski, Andrzej J ^c  

^a GEORGIA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

2 PHENYLQUINOLINE DERIVATIVE; N [2 (DIMETHYLAMINO)ETHYL] 2 [4 (4 METHYLPIPERAZINO)PHENYL]QUINOLIN 4 AMINE; OLIGODEOXYNUCLEOTIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CPG ISLAND; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG EFFECT; DRUG EFFICACY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; IMMUNOREGULATION; IMMUNOSTIMULATION; MOLECULAR INTERACTION; MOUSE; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

AMINOQUINOLINES; ANIMALS; CPG ISLANDS; IMMUNOSUPPRESSIVE AGENTS; MICE; OLIGONUCLEOTIDES; PIPERAZINES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; QUINOLINES; TUMOR CELLS, CULTURED;

EID: 0037468867     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm020374y     Document Type: Article

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