Homology modeling, molecular dynamic simulation and docking studies of cyclin dependent kinase 1

Journal of Molecular Modeling

Volumn 17, Issue 2, 2011, Pages 219-226

  Zhang, Lei ^a   Zhu, Huawei ^a   Wang, Qiang ^a   Fang, Hao ^a   Xu, Wenfang ^a   Li, Minyong ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Cyclin dependent kinase 1 (CDK1); Docking; Homology modeling; Molecular dynamic simulation; Pharmacophore identification

Indexed keywords

CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 5; CYCLIN DEPENDENT KINASE 6; CYCLIN DEPENDENT KINASE 7; CYCLIN DEPENDENT KINASE 9; CYCLIN DEPENDENT KINASE INHIBITOR; FLAVOPIRIDOL;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; HUMAN; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR MODEL; PHARMACOPHORE; PRIORITY JOURNAL; SIMULATION;

AMINO ACID SEQUENCE; BINDING SITES; CATALYTIC DOMAIN; CDC2 PROTEIN KINASE; COMPUTER SIMULATION; FLAVONOIDS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PIPERIDINES; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 77955550943     PISSN: 16102940     EISSN: 09485023     Source Type: Journal    
DOI: 10.1007/s00894-010-0710-z     Document Type: Article

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