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Volumn 405, Issue 1, 2010, Pages 193-200

Persistence of viral infection despite similar killing efficacy of antiviral CD8+ T cells during acute and chronic phases of infection

Author keywords

CD8 T cell response; Chronic infection; In vivo cytotoxicity; Killing efficacy; Mathematical models; Polyoma virus

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; CD8+ T LYMPHOCYTE; CELL SPECIFICITY; CELLULAR IMMUNITY; CONTROLLED STUDY; DISEASE CLASSIFICATION; EFFECTOR CELL; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MOUSE; NONHUMAN; PERSISTENT VIRUS INFECTION; POLYOMA VIRUS; PRIORITY JOURNAL;

EID: 77955514164     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2010.05.029     Document Type: Article
Times cited : (16)

References (53)
  • 1
    • 33845750574 scopus 로고    scopus 로고
    • Inhibitory effect of gamma interferon on BK virus gene expression and replication
    • Abend J.R., Low J.A., Imperiale M.J. Inhibitory effect of gamma interferon on BK virus gene expression and replication. J. Virol. 2007, 81:272-279.
    • (2007) J. Virol. , vol.81 , pp. 272-279
    • Abend, J.R.1    Low, J.A.2    Imperiale, M.J.3
  • 2
    • 34248399247 scopus 로고    scopus 로고
    • Impaired NFAT nuclear translocation results in split exhaustion of virus-specific CD8+ T cell functions during chronic viral infection
    • Agnellini P., Wolint P., Rehr M., Cahenzli J., Karrer U., Oxenius A. Impaired NFAT nuclear translocation results in split exhaustion of virus-specific CD8+ T cell functions during chronic viral infection. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:4565-4570.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 4565-4570
    • Agnellini, P.1    Wolint, P.2    Rehr, M.3    Cahenzli, J.4    Karrer, U.5    Oxenius, A.6
  • 4
    • 36148936559 scopus 로고    scopus 로고
    • Dynamics of CD8+ T cell responses during acute and chronic lymphocytic choriomeningitis virus infection
    • Althaus C., Ganusov V., De Boer R. Dynamics of CD8+ T cell responses during acute and chronic lymphocytic choriomeningitis virus infection. J. Immunol. 2007, 179:2944-2951.
    • (2007) J. Immunol. , vol.179 , pp. 2944-2951
    • Althaus, C.1    Ganusov, V.2    De Boer, R.3
  • 5
    • 13444270503 scopus 로고    scopus 로고
    • The role of models in understanding CD8+ T-cell memory
    • Antia R., Ganusov V., Ahmed R. The role of models in understanding CD8+ T-cell memory. Nat. Rev. Immunol. 2005, 5:101-111.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 101-111
    • Antia, R.1    Ganusov, V.2    Ahmed, R.3
  • 6
    • 0036302172 scopus 로고    scopus 로고
    • Programmed contraction of CD8(+) T cells after infection
    • Badovinac V., Porter B., Harty J. Programmed contraction of CD8(+) T cells after infection. Nat. Immunol. 2002, 3:619-626.
    • (2002) Nat. Immunol. , vol.3 , pp. 619-626
    • Badovinac, V.1    Porter, B.2    Harty, J.3
  • 7
    • 0038128194 scopus 로고    scopus 로고
    • Cutting edge: rapid in vivo killing by memory CD8 T cells
    • Barber D., Wherry E., Ahmed R. Cutting edge: rapid in vivo killing by memory CD8 T cells. J. Immunol. 2003, 171:27-31.
    • (2003) J. Immunol. , vol.171 , pp. 27-31
    • Barber, D.1    Wherry, E.2    Ahmed, R.3
  • 13
    • 0038467217 scopus 로고    scopus 로고
    • Cutting edge: rapid in vivo CTL activity by polyoma virus-specific effector and memory CD8+ T cells
    • Byers A., Kemball C., Moser J., Lukacher A. Cutting edge: rapid in vivo CTL activity by polyoma virus-specific effector and memory CD8+ T cells. J. Immunol. 2003, 171:17-21.
    • (2003) J. Immunol. , vol.171 , pp. 17-21
    • Byers, A.1    Kemball, C.2    Moser, J.3    Lukacher, A.4
  • 14
    • 33846447785 scopus 로고    scopus 로고
    • Protection against polyoma virus-induced tumors is perforin-independent
    • Byers A.M., Hadley A., Lukacher A.E. Protection against polyoma virus-induced tumors is perforin-independent. Virology 2007, 358:485-492.
    • (2007) Virology , vol.358 , pp. 485-492
    • Byers, A.M.1    Hadley, A.2    Lukacher, A.E.3
  • 15
    • 64249165996 scopus 로고    scopus 로고
    • Protective antigen-independent CD8 T cell memory is maintained during {gamma}-herpesvirus persistence
    • Cush S.S., Flano E. Protective antigen-independent CD8 T cell memory is maintained during {gamma}-herpesvirus persistence. J. Immunol. 2009, 182:3995-4004.
    • (2009) J. Immunol. , vol.182 , pp. 3995-4004
    • Cush, S.S.1    Flano, E.2
  • 16
    • 34250889282 scopus 로고    scopus 로고
    • Memory generation and maintenance of CD8+ T cell function during viral persistence
    • Cush S.S., Anderson K.M., Ravneberg D.H., Weslow-Schmidt J.L., Flano E. Memory generation and maintenance of CD8+ T cell function during viral persistence. J. Immunol. 2007, 179:141-153.
    • (2007) J. Immunol. , vol.179 , pp. 141-153
    • Cush, S.S.1    Anderson, K.M.2    Ravneberg, D.H.3    Weslow-Schmidt, J.L.4    Flano, E.5
  • 17
    • 0034765725 scopus 로고    scopus 로고
    • Recruitment times, proliferation, and apoptosis rates during the CD8(+) T-cell response to lymphocytic choriomeningitis virus
    • De Boer R.J., Oprea M., Antia R., Murali-Krishna K., Ahmed R., Perelson A.S. Recruitment times, proliferation, and apoptosis rates during the CD8(+) T-cell response to lymphocytic choriomeningitis virus. J. Virol. 2001, 75:10663-10669.
    • (2001) J. Virol. , vol.75 , pp. 10663-10669
    • De Boer, R.J.1    Oprea, M.2    Antia, R.3    Murali-Krishna, K.4    Ahmed, R.5    Perelson, A.S.6
  • 18
    • 0141958258 scopus 로고    scopus 로고
    • Different dynamics of CD4(+) and CD8(+) T cell responses during and after acute lymphocytic choriomeningitis virus infection
    • De Boer R., Homann D., Perelson A. Different dynamics of CD4(+) and CD8(+) T cell responses during and after acute lymphocytic choriomeningitis virus infection. J. Immunol. 2003, 171:3928-3935.
    • (2003) J. Immunol. , vol.171 , pp. 3928-3935
    • De Boer, R.1    Homann, D.2    Perelson, A.3
  • 22
    • 1642415940 scopus 로고    scopus 로고
    • Maintenance, loss, and resurgence of T cell responses during acute, protracted, and chronic viral infections
    • Fuller M., Khanolkar A., Tebo A., Zajac A. Maintenance, loss, and resurgence of T cell responses during acute, protracted, and chronic viral infections. J. Immunol. 2004, 172:4204-4214.
    • (2004) J. Immunol. , vol.172 , pp. 4204-4214
    • Fuller, M.1    Khanolkar, A.2    Tebo, A.3    Zajac, A.4
  • 23
    • 33645772992 scopus 로고    scopus 로고
    • Estimating costs and benefits of CTL escape mutations in SIV/HIV infection
    • Ganusov V., De Boer R. Estimating costs and benefits of CTL escape mutations in SIV/HIV infection. PLoS Comput. Biol. 2006, 2:e24.
    • (2006) PLoS Comput. Biol. , vol.2
    • Ganusov, V.1    De Boer, R.2
  • 24
    • 56449107793 scopus 로고    scopus 로고
    • Estimating in vivo death rates of targets due to CD8 T-cell-mediated killing
    • Ganusov V.V., De Boer R.J. Estimating in vivo death rates of targets due to CD8 T-cell-mediated killing. J. Virol. 2008, 82:11749-11757.
    • (2008) J. Virol. , vol.82 , pp. 11749-11757
    • Ganusov, V.V.1    De Boer, R.J.2
  • 25
    • 34548810955 scopus 로고    scopus 로고
    • IL-2 regulates expansion of CD4+ T cell populations by affecting cell death: insights from modeling CFSE data
    • Ganusov V., Milutinovic D., De Boer R. IL-2 regulates expansion of CD4+ T cell populations by affecting cell death: insights from modeling CFSE data. J. Immunol. 2007, 179:950-957.
    • (2007) J. Immunol. , vol.179 , pp. 950-957
    • Ganusov, V.1    Milutinovic, D.2    De Boer, R.3
  • 26
    • 0026443849 scopus 로고
    • Adaptive cellular interactions in the immune system: the tunable activation threshold and the significance of subthreshold responses
    • Grossman Z., Paul W. Adaptive cellular interactions in the immune system: the tunable activation threshold and the significance of subthreshold responses. Proc. Natl. Acad. Sci. U. S. A. 1992, 89:10365-10369.
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 10365-10369
    • Grossman, Z.1    Paul, W.2
  • 27
    • 0029855923 scopus 로고    scopus 로고
    • Tuning of activation thresholds explains flexibility in the selection and development of T cells in the thymus
    • Grossman Z., Singer A. Tuning of activation thresholds explains flexibility in the selection and development of T cells in the thymus. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:14747-14752.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 14747-14752
    • Grossman, Z.1    Singer, A.2
  • 28
    • 36549035669 scopus 로고    scopus 로고
    • Tracing tolerance and immunity in vivo by CFSE-labeling of administered cells
    • Ingulli E. Tracing tolerance and immunity in vivo by CFSE-labeling of administered cells. Methods Mol. Biol. 2007, 380:365-376.
    • (2007) Methods Mol. Biol. , vol.380 , pp. 365-376
    • Ingulli, E.1
  • 29
    • 0035348175 scopus 로고    scopus 로고
    • Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naive cells
    • Kaech S.M., Ahmed R. Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naive cells. Nat. Immunol. 2001, 2:415-422.
    • (2001) Nat. Immunol. , vol.2 , pp. 415-422
    • Kaech, S.M.1    Ahmed, R.2
  • 30
    • 0036550559 scopus 로고    scopus 로고
    • Effector and memory T-cell differentiation: implications for vaccine development
    • Kaech S.M., Wherry E.J., Ahmed R. Effector and memory T-cell differentiation: implications for vaccine development. Nat. Rev. Immunol. 2002, 2:251-262.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 251-262
    • Kaech, S.M.1    Wherry, E.J.2    Ahmed, R.3
  • 31
    • 20444411930 scopus 로고    scopus 로고
    • Late priming and variability of epitope-specific CD8+ T cell responses during a persistent virus infection
    • Kemball C.C., Lee E.D., Vezys V., Pearson T.C., Larsen C.P., Lukacher A.E. Late priming and variability of epitope-specific CD8+ T cell responses during a persistent virus infection. J. Immunol. 2005, 174:7950-7960.
    • (2005) J. Immunol. , vol.174 , pp. 7950-7960
    • Kemball, C.C.1    Lee, E.D.2    Vezys, V.3    Pearson, T.C.4    Larsen, C.P.5    Lukacher, A.E.6
  • 35
    • 0033568287 scopus 로고    scopus 로고
    • Visualization of polyoma virus-specific CD8+ T cells in vivo during infection and tumor rejection
    • Lukacher A., Moser J., Hadley A., Altman J. Visualization of polyoma virus-specific CD8+ T cells in vivo during infection and tumor rejection. J. Immunol. 1999, 163:3369-3378.
    • (1999) J. Immunol. , vol.163 , pp. 3369-3378
    • Lukacher, A.1    Moser, J.2    Hadley, A.3    Altman, J.4
  • 36
    • 34447137040 scopus 로고    scopus 로고
    • Interleukin-10 plays an early role in generating virus-specific T cell anergy
    • Maris C., Chappell C., Jacob J. Interleukin-10 plays an early role in generating virus-specific T cell anergy. BMC Immunol. 2007, 8:8.
    • (2007) BMC Immunol. , vol.8 , pp. 8
    • Maris, C.1    Chappell, C.2    Jacob, J.3
  • 37
    • 33845452898 scopus 로고    scopus 로고
    • Rulers over randomness: stroma cells guide lymphocyte migration in lymph nodes
    • Mempel T., Junt T., von Andrian U. Rulers over randomness: stroma cells guide lymphocyte migration in lymph nodes. Immunity 2006, 25:867-869.
    • (2006) Immunity , vol.25 , pp. 867-869
    • Mempel, T.1    Junt, T.2    von Andrian, U.3
  • 38
    • 22544475335 scopus 로고    scopus 로고
    • Role of thymic output in regulating CD8 T-cell homeostasis during acute and chronic viral infection
    • Miller N., Bonczyk J., Nakayama Y., Suresh M. Role of thymic output in regulating CD8 T-cell homeostasis during acute and chronic viral infection. J. Virol. 2005, 79:9419-9429.
    • (2005) J. Virol. , vol.79 , pp. 9419-9429
    • Miller, N.1    Bonczyk, J.2    Nakayama, Y.3    Suresh, M.4
  • 40
    • 33748482479 scopus 로고    scopus 로고
    • Gammaherpesvirus persistence alters key CD8 T-cell memory characteristics and enhances antiviral protection
    • Obar J.J., Fuse S., Leung E.K., Bellfy S.C., Usherwood E.J. Gammaherpesvirus persistence alters key CD8 T-cell memory characteristics and enhances antiviral protection. J. Virol. 2006, 80:8303-8315.
    • (2006) J. Virol. , vol.80 , pp. 8303-8315
    • Obar, J.J.1    Fuse, S.2    Leung, E.K.3    Bellfy, S.C.4    Usherwood, E.J.5
  • 41
    • 0032534058 scopus 로고    scopus 로고
    • Differentiation of naive CTL to effector and memory CTL: correlation of effector function with phenotype and cell division
    • Oehen S., Brduscha-Riem K. Differentiation of naive CTL to effector and memory CTL: correlation of effector function with phenotype and cell division. J. Immunol. 1998, 161:5338-5346.
    • (1998) J. Immunol. , vol.161 , pp. 5338-5346
    • Oehen, S.1    Brduscha-Riem, K.2
  • 42
    • 0029967721 scopus 로고    scopus 로고
    • HIV-1 dynamics in vivo: virion clearance rate, infected cell lifespan, and viral generation time
    • Perelson A., Neumann A., Markowitz M., Leonard J., Ho D. HIV-1 dynamics in vivo: virion clearance rate, infected cell lifespan, and viral generation time. Science 1996, 271:1582-1586.
    • (1996) Science , vol.271 , pp. 1582-1586
    • Perelson, A.1    Neumann, A.2    Markowitz, M.3    Leonard, J.4    Ho, D.5
  • 43
    • 33846798392 scopus 로고    scopus 로고
    • Estimation of the rate of killing by cytotoxic T lymphocytes in vivo
    • Regoes R., Barber D., Ahmed R., Antia R. Estimation of the rate of killing by cytotoxic T lymphocytes in vivo. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:1599-1603.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 1599-1603
    • Regoes, R.1    Barber, D.2    Ahmed, R.3    Antia, R.4
  • 44
    • 44449125094 scopus 로고    scopus 로고
    • Resisting immune exhaustion in HIV-1 infection
    • Rowland-Jones S., de Silva T. Resisting immune exhaustion in HIV-1 infection. PLoS Med. 2008, 5:e103.
    • (2008) PLoS Med. , vol.5
    • Rowland-Jones, S.1    de Silva, T.2
  • 45
    • 0034889233 scopus 로고    scopus 로고
    • Functional avidity maturation of CD8(+) T cells without selection of higher affinity TCR
    • Slifka M.K., Whitton J.L. Functional avidity maturation of CD8(+) T cells without selection of higher affinity TCR. Nat. Immunol. 2001, 2:711-717.
    • (2001) Nat. Immunol. , vol.2 , pp. 711-717
    • Slifka, M.K.1    Whitton, J.L.2
  • 47
    • 33749342911 scopus 로고    scopus 로고
    • Continuous recruitment of naive T cells contributes to heterogeneity of antiviral CD8 T cells during persistent infection
    • Vezys V., Masopust D., Kemball C., Barber D., O'Mara L., Larsen C., Pearson T., Ahmed R., Lukacher A. Continuous recruitment of naive T cells contributes to heterogeneity of antiviral CD8 T cells during persistent infection. J. Exp. Med. 2006, 203:2263-2269.
    • (2006) J. Exp. Med. , vol.203 , pp. 2263-2269
    • Vezys, V.1    Masopust, D.2    Kemball, C.3    Barber, D.4    O'Mara, L.5    Larsen, C.6    Pearson, T.7    Ahmed, R.8    Lukacher, A.9
  • 48
    • 2442684151 scopus 로고    scopus 로고
    • Memory CD8 T-cell differentiation during viral infection
    • Wherry E., Ahmed R. Memory CD8 T-cell differentiation during viral infection. J. Virol. 2004, 78:5535-5545.
    • (2004) J. Virol. , vol.78 , pp. 5535-5545
    • Wherry, E.1    Ahmed, R.2
  • 49
    • 0037383592 scopus 로고    scopus 로고
    • Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment
    • Wherry E., Blattman J., Murali-Krishna K., Van Der Most R., Ahmed R. Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment. J. Virol. 2003, 77:4911-4927.
    • (2003) J. Virol. , vol.77 , pp. 4911-4927
    • Wherry, E.1    Blattman, J.2    Murali-Krishna, K.3    Van Der Most, R.4    Ahmed, R.5
  • 53
    • 62249131518 scopus 로고    scopus 로고
    • Complete but curtailed T-cell response to very low-affinity antigen
    • Zehn D., Lee S.Y., Bevan M.J. Complete but curtailed T-cell response to very low-affinity antigen. Nature 2009, 458:211-214.
    • (2009) Nature , vol.458 , pp. 211-214
    • Zehn, D.1    Lee, S.Y.2    Bevan, M.J.3


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