Interaction kinetics of oximes with native, phosphylated and aged human acetylcholinesterase

Chemico-Biological Interactions

Volumn 187, Issue 1-3, 2010, Pages 163-166

  Radić, Zoran ^a   Kalisiak, Jaroslaw ^b   Fokin, Valery V ^b   Sharpless, K Barry ^b   Taylor, Palmer ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Acetylcholinesterase; Butyrylcholinesterase; Organophosphate; Oxime; Reactivation

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; ACETYLCHOLINESTERASE; CYCLOSARIN; METHYLPHOSPHONOTHIOIC ACID S (2 DIISOPROPYLAMINOETHYL) O ETHYL ESTER; OXIME DERIVATIVE; PARAOXON; PRALIDOXIME; SERINE; SOMAN;

ARTICLE; BINDING KINETICS; COMPLEX FORMATION; CONTROLLED STUDY; DEALKYLATION; DISSOCIATION CONSTANT; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; EMBRYO; ENZYME ACTIVE SITE; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL;

EID: 77955512718     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2010.04.014     Document Type: Article

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