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Volumn 139, Issue 2, 2010, Pages

Insulin-like growth factor axis gene polymorphisms and clinical outcomes in pancreatic cancer

Author keywords

Insulin Like Growth Factor Axis; Overall Survival; Pancreatic Cancer; Single Nucleotide Polymorphism

Indexed keywords

DNA; SOMATOMEDIN; SOMATOMEDIN B; SOMATOMEDIN B RECEPTOR; SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN BINDING PROTEIN 5; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; INSULIN RECEPTOR SUBSTRATE; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN RECEPTOR;

EID: 77955497635     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2010.04.042     Document Type: Article
Times cited : (49)

References (34)
  • 2
    • 58149252481 scopus 로고    scopus 로고
    • Improving gemcitabine-mediated radiosensitization using molecularly targeted therapy: A review
    • M.A. Morgan, L.A. Parsels, J. Maybaum, et al. Improving gemcitabine-mediated radiosensitization using molecularly targeted therapy: a review Clin Cancer Res 14 2008 6744 6750
    • (2008) Clin Cancer Res , vol.14 , pp. 6744-6750
    • Morgan, M.A.1    Parsels, L.A.2    Maybaum, J.3
  • 3
    • 0032841435 scopus 로고    scopus 로고
    • Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling
    • D.J. Withers, D.J. Burks, H.H. Towery, et al. Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling Nat Genet 23 1999 32 40
    • (1999) Nat Genet , vol.23 , pp. 32-40
    • Withers, D.J.1    Burks, D.J.2    Towery, H.H.3
  • 4
    • 31044446941 scopus 로고    scopus 로고
    • Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth
    • X. Dong, S. Park, X. Lin, et al. Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth J Clin Invest 116 2006 101 114
    • (2006) J Clin Invest , vol.116 , pp. 101-114
    • Dong, X.1    Park, S.2    Lin, X.3
  • 5
    • 33846874575 scopus 로고    scopus 로고
    • The role of the IGF system in cancer growth and metastasis: Overview and recent insights
    • A.A. Samani, S. Yakar, D. LeRoith, et al. The role of the IGF system in cancer growth and metastasis: overview and recent insights Endocr Rev 28 2007 20 47
    • (2007) Endocr Rev , vol.28 , pp. 20-47
    • Samani, A.A.1    Yakar, S.2    LeRoith, D.3
  • 6
    • 56749184290 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor signalling in neoplasia
    • M. Pollak Insulin and insulin-like growth factor signalling in neoplasia Nat Rev Cancer 8 2008 915 928
    • (2008) Nat Rev Cancer , vol.8 , pp. 915-928
    • Pollak, M.1
  • 7
    • 54249117292 scopus 로고    scopus 로고
    • Feedback mechanisms promote cooperativity for small molecule inhibitors of epidermal and insulin-like growth factor receptors
    • E. Buck, A. Eyzaguirre, M. Rosenfeld-Franklin, et al. Feedback mechanisms promote cooperativity for small molecule inhibitors of epidermal and insulin-like growth factor receptors Cancer Res 68 2008 8322 8332
    • (2008) Cancer Res , vol.68 , pp. 8322-8332
    • Buck, E.1    Eyzaguirre, A.2    Rosenfeld-Franklin, M.3
  • 8
    • 46749156706 scopus 로고    scopus 로고
    • Acquired resistance to EGFR tyrosine kinase inhibitors in cancer cells is mediated by loss of IGF-binding proteins
    • M. Guix, A.C. Faber, S.E. Wang, et al. Acquired resistance to EGFR tyrosine kinase inhibitors in cancer cells is mediated by loss of IGF-binding proteins J Clin Invest 118 2008 2609 2619
    • (2008) J Clin Invest , vol.118 , pp. 2609-2619
    • Guix, M.1    Faber, A.C.2    Wang, S.E.3
  • 9
    • 33744927684 scopus 로고    scopus 로고
    • Epidermal growth factor induces insulin receptor substrate-2 in breast cancer cells via c-Jun NH(2)-terminal kinase/activator protein-1 signaling to regulate cell migration
    • X. Cui, H.J. Kim, I. Kuiatse, et al. Epidermal growth factor induces insulin receptor substrate-2 in breast cancer cells via c-Jun NH(2)-terminal kinase/activator protein-1 signaling to regulate cell migration Cancer Res 66 2006 5304 5313
    • (2006) Cancer Res , vol.66 , pp. 5304-5313
    • Cui, X.1    Kim, H.J.2    Kuiatse, I.3
  • 10
    • 33748310896 scopus 로고    scopus 로고
    • Regulatory role of c-Met in insulin-like growth factor-I receptor-mediated migration and invasion of human pancreatic carcinoma cells
    • T.W. Bauer, R.J. Somcio, F. Fan, et al. Regulatory role of c-Met in insulin-like growth factor-I receptor-mediated migration and invasion of human pancreatic carcinoma cells Mol Cancer Ther 5 2006 1676 1682
    • (2006) Mol Cancer Ther , vol.5 , pp. 1676-1682
    • Bauer, T.W.1    Somcio, R.J.2    Fan, F.3
  • 11
    • 0027182367 scopus 로고
    • The function of GRB2 in linking the insulin receptor to Ras signaling pathways
    • E.Y. Skolnik, A. Batzer, N. Li, et al. The function of GRB2 in linking the insulin receptor to Ras signaling pathways Science 260 1993 1953 1955
    • (1993) Science , vol.260 , pp. 1953-1955
    • Skolnik, E.Y.1    Batzer, A.2    Li, N.3
  • 12
    • 33745220580 scopus 로고    scopus 로고
    • Synergy between an IGF-1R antibody and Raf/MEK/ERK and PI3K/Akt/mTOR pathway inhibitors in suppressing IGF-1R-mediated growth in hematopoietic cells
    • F.E. Bertrand, L.S. Steelman, W.H. Chappell, et al. Synergy between an IGF-1R antibody and Raf/MEK/ERK and PI3K/Akt/mTOR pathway inhibitors in suppressing IGF-1R-mediated growth in hematopoietic cells Leukemia 20 2006 1254 1260
    • (2006) Leukemia , vol.20 , pp. 1254-1260
    • Bertrand, F.E.1    Steelman, L.S.2    Chappell, W.H.3
  • 13
    • 47549108868 scopus 로고    scopus 로고
    • Insulin receptor substrate-1 involvement in epidermal growth factor receptor and insulin-like growth factor receptor signalling: Implication for Gefitinib ('Iressa') response and resistance
    • J.M. Knowlden, H.E. Jones, D. Barrow, et al. Insulin receptor substrate-1 involvement in epidermal growth factor receptor and insulin-like growth factor receptor signalling: implication for Gefitinib ('Iressa') response and resistance Breast Cancer Res Treat 111 2008 79 91
    • (2008) Breast Cancer Res Treat , vol.111 , pp. 79-91
    • Knowlden, J.M.1    Jones, H.E.2    Barrow, D.3
  • 14
    • 12144290914 scopus 로고    scopus 로고
    • Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors
    • C.S. Mitsiades, N.S. Mitsiades, C.J. McMullan, et al. Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors Cancer Cell 5 2004 221 230
    • (2004) Cancer Cell , vol.5 , pp. 221-230
    • Mitsiades, C.S.1    Mitsiades, N.S.2    McMullan, C.J.3
  • 15
    • 63749130819 scopus 로고    scopus 로고
    • Significant associations of mismatch repair gene polymorphisms with clinical outcome of pancreatic cancer
    • X. Dong, L. Jiao, Y. Li, et al. Significant associations of mismatch repair gene polymorphisms with clinical outcome of pancreatic cancer J Clin Oncol 27 2009 1592 1599
    • (2009) J Clin Oncol , vol.27 , pp. 1592-1599
    • Dong, X.1    Jiao, L.2    Li, Y.3
  • 16
    • 38549158538 scopus 로고    scopus 로고
    • F-SNP: Computationally predicted functional SNPs for disease association studies
    • P.H. Lee, and H. Shatkay F-SNP: computationally predicted functional SNPs for disease association studies Nucleic Acids Res 36 2008 D820 D824
    • (2008) Nucleic Acids Res , vol.36
    • Lee, P.H.1    Shatkay, H.2
  • 17
    • 0038156106 scopus 로고    scopus 로고
    • Estimating the occurrence of false positives and false negatives in microarray studies by approximating and partitioning the empirical distribution of p-values
    • S. Pounds, and S.W. Morris Estimating the occurrence of false positives and false negatives in microarray studies by approximating and partitioning the empirical distribution of p-values Bioinformatics 19 2003 1236 1242
    • (2003) Bioinformatics , vol.19 , pp. 1236-1242
    • Pounds, S.1    Morris, S.W.2
  • 18
    • 49749123796 scopus 로고    scopus 로고
    • IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: Findings from the Breast and Prostate Cancer Cohort Consortium (BPC3)
    • A.V. Patel, I. Cheng, F. Canzian, et al. IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3) PLoS One 3 2008 e2578
    • (2008) PLoS One , vol.3
    • Patel, A.V.1    Cheng, I.2    Canzian, F.3
  • 19
    • 2542494029 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-3 is a novel mediator of apoptosis in insulin-secreting cells
    • M.L. Shim, L.E. Levitt Katz, J. Davis, et al. Insulin-like growth factor binding protein-3 is a novel mediator of apoptosis in insulin-secreting cells Growth Horm IGF Res 14 2004 216 225
    • (2004) Growth Horm IGF Res , vol.14 , pp. 216-225
    • Shim, M.L.1    Levitt Katz, L.E.2    Davis, J.3
  • 20
    • 70450255319 scopus 로고    scopus 로고
    • Phenotypes and genotypes of insulin-like growth factor 1, IGF-binding protein-3 and cancer risk: Evidence from 96 studies
    • W. Chen, S. Wang, T. Tian, et al. Phenotypes and genotypes of insulin-like growth factor 1, IGF-binding protein-3 and cancer risk: evidence from 96 studies Eur J Hum Genet 17 2009 1668 1675
    • (2009) Eur J Hum Genet , vol.17 , pp. 1668-1675
    • Chen, W.1    Wang, S.2    Tian, T.3
  • 21
    • 34548038590 scopus 로고    scopus 로고
    • Circulating insulin-like growth factor binding protein-1 and the risk of pancreatic cancer
    • B.M. Wolpin, D.S. Michaud, E.L. Giovannucci, et al. Circulating insulin-like growth factor binding protein-1 and the risk of pancreatic cancer Cancer Res 67 2007 7923 7928
    • (2007) Cancer Res , vol.67 , pp. 7923-7928
    • Wolpin, B.M.1    Michaud, D.S.2    Giovannucci, E.L.3
  • 22
    • 33750473748 scopus 로고    scopus 로고
    • Differential expression of insulin-like growth factor binding protein-5 in pancreatic adenocarcinomas: Identification using DNA microarray
    • S.K. Johnson, R.A. Dennis, G.W. Barone, et al. Differential expression of insulin-like growth factor binding protein-5 in pancreatic adenocarcinomas: identification using DNA microarray Mol Carcinog 45 2006 814 827
    • (2006) Mol Carcinog , vol.45 , pp. 814-827
    • Johnson, S.K.1    Dennis, R.A.2    Barone, G.W.3
  • 23
    • 70349569525 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-5 influences pancreatic cancer cell growth
    • S.K. Johnson, and R.S. Haun Insulin-like growth factor binding protein-5 influences pancreatic cancer cell growth World J Gastroenterol 15 2009 3355 3366
    • (2009) World J Gastroenterol , vol.15 , pp. 3355-3366
    • Johnson, S.K.1    Haun, R.S.2
  • 24
    • 55149110908 scopus 로고    scopus 로고
    • Transgenic mice overexpressing human G972R IRS-1 show impaired insulin action and insulin secretion
    • M.L. Hribal, F. Tornei, A. Pujol, et al. Transgenic mice overexpressing human G972R IRS-1 show impaired insulin action and insulin secretion J Cell Mol Med 12 2008 2096 2106
    • (2008) J Cell Mol Med , vol.12 , pp. 2096-2106
    • Hribal, M.L.1    Tornei, F.2    Pujol, A.3
  • 25
    • 0032587076 scopus 로고    scopus 로고
    • The Gly972→Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cells
    • O. Porzio, M. Federici, M.L. Hribal, et al. The Gly972→Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cells J Clin Invest 104 1999 357 364
    • (1999) J Clin Invest , vol.104 , pp. 357-364
    • Porzio, O.1    Federici, M.2    Hribal, M.L.3
  • 26
    • 0029118510 scopus 로고
    • Insulin resistance: Interactions between obesity and a common variant of insulin receptor substrate-1
    • J.O. Clausen, T. Hansen, C. Bjorbaek, et al. Insulin resistance: interactions between obesity and a common variant of insulin receptor substrate-1 Lancet 346 1995 397 402
    • (1995) Lancet , vol.346 , pp. 397-402
    • Clausen, J.O.1    Hansen, T.2    Bjorbaek, C.3
  • 27
    • 0034351407 scopus 로고    scopus 로고
    • The Gly→Arg972 amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells
    • M.L. Hribal, M. Federici, O. Porzio, et al. The Gly→Arg972 amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells J Clin Endocrinol Metab 85 2000 2004 2013
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2004-2013
    • Hribal, M.L.1    Federici, M.2    Porzio, O.3
  • 28
    • 14844336893 scopus 로고    scopus 로고
    • Human insulin receptor substrate-1 (IRS-1) polymorphism G972R causes IRS-1 to associate with the insulin receptor and inhibit receptor autophosphorylation
    • A.J. McGettrick, E.P. Feener, and C.R. Kahn Human insulin receptor substrate-1 (IRS-1) polymorphism G972R causes IRS-1 to associate with the insulin receptor and inhibit receptor autophosphorylation J Biol Chem 280 2005 6441 6446
    • (2005) J Biol Chem , vol.280 , pp. 6441-6446
    • McGettrick, A.J.1    Feener, E.P.2    Kahn, C.R.3
  • 29
    • 33244484120 scopus 로고    scopus 로고
    • The G972R variant of the insulin receptor substrate-1 gene impairs insulin signaling and cell differentiation in 3T3L1 adipocytes; Treatment with a PPARgamma agonist restores normal cell signaling and differentiation
    • F. Sentinelli, E. Filippi, M.G. Cavallo, et al. The G972R variant of the insulin receptor substrate-1 gene impairs insulin signaling and cell differentiation in 3T3L1 adipocytes; treatment with a PPARgamma agonist restores normal cell signaling and differentiation J Endocrinol 188 2006 271 285
    • (2006) J Endocrinol , vol.188 , pp. 271-285
    • Sentinelli, F.1    Filippi, E.2    Cavallo, M.G.3
  • 30
    • 0029890372 scopus 로고    scopus 로고
    • Increased expression of insulin receptor substrate-1 in human pancreatic cancer
    • U. Bergmann, H. Funatomi, M. Kornmann, et al. Increased expression of insulin receptor substrate-1 in human pancreatic cancer Biochem Biophys Res Commun 220 1996 886 890
    • (1996) Biochem Biophys Res Commun , vol.220 , pp. 886-890
    • Bergmann, U.1    Funatomi, H.2    Kornmann, M.3
  • 31
    • 27144478642 scopus 로고    scopus 로고
    • Insulin receptor substrate is a mediator of phosphoinositide 3-kinase activation in quiescent pancreatic cancer cells
    • T. Asano, Y. Yao, S. Shin, et al. Insulin receptor substrate is a mediator of phosphoinositide 3-kinase activation in quiescent pancreatic cancer cells Cancer Res 65 2005 9164 9168
    • (2005) Cancer Res , vol.65 , pp. 9164-9168
    • Asano, T.1    Yao, Y.2    Shin, S.3
  • 32
    • 60549112878 scopus 로고    scopus 로고
    • Insulin receptor substrate-2 mediated insulin-like growth factor-I receptor overexpression in pancreatic adenocarcinoma through protein kinase Cdelta
    • J. Kwon, S. Stephan, A. Mukhopadhyay, et al. Insulin receptor substrate-2 mediated insulin-like growth factor-I receptor overexpression in pancreatic adenocarcinoma through protein kinase Cdelta Cancer Res 69 2009 1350 1357
    • (2009) Cancer Res , vol.69 , pp. 1350-1357
    • Kwon, J.1    Stephan, S.2    Mukhopadhyay, A.3
  • 33
    • 1042301429 scopus 로고    scopus 로고
    • Role of insulin receptor substrates and protein kinase C-zeta in vascular permeability factor/vascular endothelial growth factor expression in pancreatic cancer cells
    • M. Neid, K. Datta, S. Stephan, et al. Role of insulin receptor substrates and protein kinase C-zeta in vascular permeability factor/vascular endothelial growth factor expression in pancreatic cancer cells J Biol Chem 279 2004 3941 3948
    • (2004) J Biol Chem , vol.279 , pp. 3941-3948
    • Neid, M.1    Datta, K.2    Stephan, S.3
  • 34
    • 64049103845 scopus 로고    scopus 로고
    • Mannose 6-phosphate/insulin-like growth factor 2 receptor limits cell invasion by controlling alphaVbeta3 integrin expression and proteolytic processing of urokinase-type plasminogen activator receptor
    • H.B. Schiller, A. Szekeres, B.R. Binder, et al. Mannose 6-phosphate/insulin-like growth factor 2 receptor limits cell invasion by controlling alphaVbeta3 integrin expression and proteolytic processing of urokinase-type plasminogen activator receptor Mol Biol Cell 20 2009 745 756
    • (2009) Mol Biol Cell , vol.20 , pp. 745-756
    • Schiller, H.B.1    Szekeres, A.2    Binder, B.R.3


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