Ovine reference materials and assays for prion genetic testing

BMC Veterinary Research

Volumn 6, Issue , 2010, Pages

  Heaton, Michael P ^a   Leymaster, Kreg A ^a   Kalbfleisch, Theodore S ^b   Freking, Brad A ^a   Smith, Timothy P L ^a   Clawson, Michael L ^a   Laegreid, William W ^a,c  

^a U S MEAT ANIMAL RESEARCH CENTER   (United States)

^b UNIVERSITY OF LOUISVILLE   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OVIS; OVIS ARIES;

ANIMAL; ARTICLE; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETIC SCREENING; GENETICS; PRION; SCRAPIE; SHEEP;

ANIMALS; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; POLYMORPHISM, GENETIC; PRIONS; SCRAPIE; SHEEP;

EID: 77955481702     PISSN: None     EISSN: 17466148     Source Type: Journal    
DOI: 10.1186/1746-6148-6-23     Document Type: Article

References (57)

1. Prusiner SB. Prions. Proc Natl Acad Sci USA 1998, 95(23):13363-13383. 10.1073/pnas.95.23.13363, 33918, 9811807.
2. Bruce ME, Will RG, Ironside JW, McConnell I, Drummond D, Suttie A, McCardle L, Chree A, Hope J, Birkett C, et al. Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent. Nature 1997, 389(6650):498-501. 10.1038/39057, 9333239.
3. Collinge J, Rossor M. A new variant of prion disease. Lancet 1996, 347(9006):916-917. 10.1016/S0140-6736(96)91407-5, 8598749.
4. Hill AF, Desbruslais M, Joiner S, Sidle KCL, Gowland I, Collinge J, Doey LJ, Lantos P. The same prion strain causes vCJD and BSE. Nature 1997, 389(6650):448-450. 526, 10.1038/38925, 9333232.
5. Will RG, Ironside JW, Zeidler M, Cousens SN, Estibeiro K, Alperovitch A, Poser S, Pocchiari M, Hofman A, Smith PG. A new variant of Creutzfeldt-Jakob disease in the UK. Lancet 1996, 347(9006):921-925. 10.1016/S0140-6736(96)91412-9, 8598754.
6. Bons N, Mestre-Frances N, Belli P, Cathala F, Gajdusek DC, Brown P. Natural and experimental oral infection of nonhuman primates by bovine spongiform encephalopathy agents. Proc Natl Acad Sci USA 1999, 96(7):4046-4051. 10.1073/pnas.96.7.4046, 22417, 10097160.
7. Sigurdson CJ, Miller MW. Other animal prion diseases. Br Med Bull 2003, 66:199-212. 10.1093/bmb/66.1.199, 14522860.
8. Schneider K, Fangerau H, Michaelsen B, Raab WH. The early history of the transmissible spongiform encephalopathies exemplified by scrapie. Brain Res Bull 2008, 77(6):343-355. 10.1016/j.brainresbull.2008.09.012, 18951958.
9. Baylis M, Goldmann W, Houston F, Cairns D, Chong A, Ross A, Smith A, Hunter N, McLean AR. Scrapie epidemic in a fully PrP-genotyped sheep flock. J Gen Virol 2002, 83(Pt 11):2907-2914.
10. Belt PB, Muileman IH, Schreuder BE, Bos-de Ruijter J, Gielkens AL, Smits MA. Identification of five allelic variants of the sheep PrP gene and their association with natural scrapie. J Gen Virol 1995, 76(Pt 3):509-517. 10.1099/0022-1317-76-3-509, 7897344.
11. Hunter N, Foster JD, Goldmann W, Stear MJ, Hope J, Bostock C. Natural scrapie in a closed flock of Cheviot sheep occurs only in specific PrP genotypes. Arch Virol 1996, 141(5):809-824. 10.1007/BF01718157, 8678828.
12. Baylis M, Goldmann W. The genetics of scrapie in sheep and goats. Curr Mol Med 2004, 4(4):385-396. 10.2174/1566524043360672, 15354869.
13. Goldmann W. PrP genetics in ruminant transmissible spongiform encephalopathies. Vet Res 2008, 39(4):30. 10.1051/vetres:2008010, 18284908.
14. Gubbins S, Webb CR. Simulation of the options for a national control programme to eradicate scrapie from Great Britain. Prev Vet Med 2005, 69(3-4):175-187.
15. Compulsory scrapie flocks scheme booklet. , http://www.defra.gov.uk/animalhealth/publications/NSPAC/
16. Billinis C, Psychas V, Leontides L, Spyrou V, Argyroudis S, Vlemmas I, Leontides S, Sklaviadis T, Papadopoulos O. Prion protein gene polymorphisms in healthy and scrapie-affected sheep in Greece. J Gen Virol 2004, 85(Pt 2):547-554. 10.1099/vir.0.19520-0, 14769911.
17. Benkel BF, Valle E, Bissonnette N, Hossain Farid A. Simultaneous detection of eight single nucleotide polymorphisms in the ovine prion protein gene. Mol Cell Probes 2007, 21(5-6):363-367. 10.1016/j.mcp.2007.05.002, 17590312.
18. Pongolini S, Bergamini F, Bassi S. A new genotyping strategy for efficient scoring of closely positioned SNPs in the ovine prion protein gene. Mol Cell Probes 2009, 23(2):122-125. 10.1016/j.mcp.2009.01.002, 19272344.
19. Vaccari G, Conte M, Morelli L, Di Guardo G, Petraroli R, Agrimi U. Primer extension assay for prion protein genotype determination in sheep. Mol Cell Probes 2004, 18(1):33-37. 10.1016/j.mcp.2003.06.001, 15036367.
20. Laegreid WW, Clawson ML, Heaton MP, Green BT, O'Rourke KI, Knowles DP. Scrapie resistance in ARQ sheep. J Virol 2008, 82(20):10318-10320. 10.1128/JVI.00710-08, 2566274, 18632863.
21. Zhang L, Li N, Fan B, Fang M, Xu W. PRNP polymorphisms in Chinese ovine, caprine and bovine breeds. Anim Genet 2004, 35(6):457-461. 10.1111/j.1365-2052.2004.01204.x, 15566469.
22. Vaccari G, D'Agostino C, Nonno R, Rosone F, Conte M, Di Bari MA, Chiappini B, Esposito E, De Grossi L, Giordani F, et al. Prion protein alleles showing a protective effect on the susceptibility of sheep to scrapie and bovine spongiform encephalopathy. J Virol 2007, 81(13):7306-7309. 10.1128/JVI.02880-06, 1933282, 17442723.
23. Vaccari G, Scavia G, Sala M, Cosseddu G, Chiappini B, Conte M, Esposito E, Lorenzetti R, Perfetti G, Marconi P, et al. Protective effect of the AT137RQ and ARQK176 PrP allele against classical scrapie in Sarda breed sheep. Vet Res 2009, 40(3):19. 10.1051/vetres/2009002, 2695041, 19171116.
24. Benestad SL, Arsac JN, Goldmann W, Noremark M. Atypical/Nor98 scrapie: properties of the agent, genetics, and epidemiology. Vet Res 2008, 39(4):19. 10.1051/vetres:2007056, 18187032.
25. Benestad SL, Sarradin P, Thu B, Schonheit J, Tranulis MA, Bratberg B. Cases of scrapie with unusual features in Norway and designation of a new type, Nor98. Vet Rec 2003, 153(7):202-208. 10.1136/vr.153.7.202, 12956297.
26. Luhken G, Buschmann A, Brandt H, Eiden M, Groschup MH, Erhardt G. Epidemiological and genetical differences between classical and atypical scrapie cases. Vet Res 2007, 38(1):65-80. 10.1051/vetres:2006046, 17156738.
27. Moum T, Olsaker I, Hopp P, Moldal T, Valheim M, Moum T, Benestad SL. Polymorphisms at codons 141 and 154 in the ovine prion protein gene are associated with scrapie Nor98 cases. J Gen Virol 2005, 86(Pt 1):231-235. 10.1099/vir.0.80437-0, 15604451.
28. Saunders GC, Cawthraw S, Mountjoy SJ, Hope J, Windl O. PrP genotypes of atypical scrapie cases in Great Britain. J Gen Virol 2006, 87(Pt 11):3141-3149. 10.1099/vir.0.81779-0, 17030846.
29. Goldmann W, Houston F, Stewart P, Perucchini M, Foster J, Hunter N. Ovine prion protein variant A(136)R(154)L(168)Q(171) increases resistance to experimental challenge with bovine spongiform encephalopathy agent. J Gen Virol 2006, 87(Pt 12):3741-3745. 10.1099/vir.0.82083-0, 17098993.
30. Benson DA, Karsch-Mizrachi I, Lipman DJ, Ostell J, Sayers EW. GenBank. Nucleic Acids Res 2009, (37 Database):D26-31. 10.1093/nar/gkn723, 2686462, 18940867.
31. Clawson ML, Heaton MP, Keele JW, Smith TP, Harhay GP, Laegreid WW. Prion gene haplotypes of U.S. cattle. BMC Genet 2006, 7:51. 10.1186/1471-2156-7-51, 1654178, 17092337.
32. Clawson ML, Heaton MP, Keele JW, Smith TP, Harhay GP, Richt JA, Laegreid WW. A sequencing strategy for identifying variation throughout the prion gene of BSE-affected cattle. BMC Res Notes 2008, 1:32. 10.1186/1756-0500-1-32, 2525647, 18710485.
33. Gu Y, Singh A, Bose S, Singh N. Pathogenic mutations in the glycosylphosphatidylinositol signal peptide of PrP modulate its topology in neuroblastoma cells. Mol Cell Neurosci 2008, 37(4):647-656. 10.1016/j.mcn.2007.08.018, 2693044, 18325785.
34. Hama T, Iwasaki Y, Niwa H, Yoshida M, Hashizume Y, Kitamoto T, Murakami N, Sobue G. An autopsied case of panencephalopathic-type Creutzfeldt-Jakob disease with mutation in the prion protein gene at codon 232 and type 1 prion protein. Neuropathology 2009, 29(6):727-734. 10.1111/j.1440-1789.2009.01016.x, 19422533.
35. Hoque MZ, Kitamoto T, Furukawa H, Muramoto T, Tateishi J. Mutation in the prion protein gene at codon 232 in Japanese patients with Creutzfeldt-Jakob disease: a clinicopathological, immunohistochemical and transmission study. Acta Neuropathol 1996, 92(5):441-446. 10.1007/s004010050544, 8922054.
36. Kitamoto T, Ohta M, Doh-ura K, Hitoshi S, Terao Y, Tateishi J. Novel missense variants of prion protein in Creutzfeldt-Jakob disease or Gerstmann-Straussler syndrome. Biochem Biophys Res Commun 1993, 191(2):709-714. 10.1006/bbrc.1993.1275, 8461023.
37. Shiga Y, Satoh K, Kitamoto T, Kanno S, Nakashima I, Sato S, Fujihara K, Takata H, Nobukuni K, Kuroda S, et al. Two different clinical phenotypes of Creutzfeldt-Jakob disease with a M232R substitution. J Neurol 2007, 254(11):1509-1517. 10.1007/s00415-007-0540-9, 17965961.
38. Windl O, Giese A, Schulz-Schaeffer W, Zerr I, Skworc K, Arendt S, Oberdieck C, Bodemer M, Poser S, Kretzschmar HA. Molecular genetics of human prion diseases in Germany. Hum Genet 1999, 105(3):244-252. 10.1007/s004390051096, 10987652.
39. Arsac JN, Andreoletti O, Bilheude JM, Lacroux C, Benestad SL, Baron T. Similar biochemical signatures and prion protein genotypes in atypical scrapie and Nor98 cases, France and Norway. Emerg Infect Dis 2007, 13(1):58-65. 10.3201/eid1301.060393, 2725815, 17370516.
40. Buitkamp J, Semmer J. A robust, low- to medium-throughput prnp genotyping system in sheep. BMC Infect Dis 2004, 4:30. 10.1186/1471-2334-4-30, 517712, 15345029.
41. French DJ, Jones D, McDowell DG, Thomson JA, Debenham PG. Analysis of multiple single nucleotide polymorphisms closely positioned in the ovine PRNP gene using linear fluorescent probes and melting curve analysis. BMC Infect Dis 2007, 7:90. 10.1186/1471-2334-7-90, 1994165, 17683552.
42. Garcia-Crespo D, Oporto B, Gomez N, Nagore D, Benedicto L, Juste RA, Hurtado A. PrP polymorphisms in Basque sheep breeds determined by PCR-restriction fragment length polymorphism and real-time PCR. Vet Rec 2004, 154(23):717-722. 10.1136/vr.154.23.717, 15214515.
43. Jasik A, Reichert M. Application of temperature-gradient gel electrophoresis for detection of prion protein gene polymorphisms in Polish Swiniarka sheep. J Vet Diagn Invest 2006, 18(3):270-274.
44. Johnson ML, Evoniuk JM, Stoltenow CL, O'Rourke KI, Redmer DA. Development of an assay to determine single nucleotide polymorphisms in the prion gene for the genetic diagnosis of relative susceptibility to classical scrapie in sheep. J Vet Diagn Invest 2007, 19(1):73-77.
45. Lee MA, Manley TR, Glass BC, Anderson RM, Wilson SJ, O'Keefe JS, Tisdall DJ, McEwan JC, Phua SH, Tate ML. Distribution of prion protein genotypes in breeds of sheep in New Zealand. N Z Vet J 2007, 55(5):222-227.
46. L'Homme Y, Leboeuf A, Cameron J. PrP genotype frequencies of Quebec sheep breeds determined by real-time PCR and molecular beacons. Can J Vet Res 2008, 72(4):320-324. 2442674, 18783020.
47. Lockley AK, Hosie BD, Moore L, Harling R, Bardsley RG. PCR-based detection of the polymorphism at codon 136 in the ovine prion protein gene. Anim Biotechnol 2000, 11(1):69-73. 10.1080/10495390009525949, 10885814.
48. McKay JT, Brigner TA, Caplin BE, McCurdy KS, Forde RL. A real-time polymerase chain reaction assay to detect single nucleotide polymorphisms at codon 171 in the prion gene for the genotyping of scrapie susceptibility in sheep. J Vet Diagn Invest 2008, 20(2):209-212.
49. Schutz E, Scharfenstein M, Brenig B. Genotyping of ovine prion protein gene (PRNP) variants by PCR with melting curve analysis. Clin Chem 2006, 52(7):1426-1429.
50. Van Poucke M, Vandesompele J, Mattheeuws M, Van Zeveren A, Peelman LJ. A dual fluorescent multiprobe assay for prion protein genotyping in sheep. BMC Infect Dis 2005, 5(1):13. 10.1186/1471-2334-5-13, 1274271, 15769289.
51. Yuzbasiyan-Gurkan V, Krehbiel JD, Cao Y, Venta PJ. Development and usefulness of new polymerase chain reaction-based tests for detection of different alleles at codons 136 and 171 of the ovine prion protein gene. Am J Vet Res 1999, 60(7):884-887.
52. Zsolnai A, Anton I, Kuhn C, Fesus L. Detection of single-nucleotide polymorphisms coding for three ovine prion protein variants by primer extension assay and capillary electrophoresis. Electrophoresis 2003, 24(4):634-638. 10.1002/elps.200390074, 12601731.
53. Heaton MP, Keele JW, Harhay GP, Richt JA, Koohmaraie M, Wheeler TL, Shackelford SD, Casas E, King DA, Sonstegard TS, et al. Prevalence of the prion protein gene E211K variant in U.S. cattle. BMC Vet Res 2008, 4:25. 10.1186/1746-6148-4-25, 2478677, 18625065.
54. Freking BA, Murphy SK, Wylie AA, Rhodes SJ, Keele JW, Leymaster KA, Jirtle RL, Smith TP. Identification of the single base change causing the callipyge muscle hypertrophy phenotype, the only known example of polar overdominance in mammals. Genome Res 2002, 12(10):1496-1506. 10.1101/gr.571002, 187527, 12368241.
55. Leymaster KA. Straightbred comparison of a composite population and the Suffolk breed for performance traits of sheep. J Anim Sci 1991, 69(3):993-999.
56. Nomenclature for incompletely specified bases in nucleic acid sequences. Recommendations 1984. Nomenclature Committee of the International Union of Biochemistry (NC-IUB). Proc Natl Acad Sci USA 1986, 83(1):4-8. 10.1073/pnas.83.1.4, 322779, 2417239.
57. Heaton MP, Leymaster KA, Freking BA, Hawk DA, Smith TP, Keele JW, Snelling WM, Fox JM, Chitko-McKown CG, Laegreid WW. Prion gene sequence variation within diverse groups of U.S. sheep, beef cattle, and deer. Mamm Genome 2003, 14(11):765-777. 10.1007/s00335-003-2283-y, 14722726.