Application of temperature-gradient gel electrophoresis for detection of prion protein gene polymorphisms in Polish Świniarka sheep

Journal of Veterinary Diagnostic Investigation

Volumn 18, Issue 3, 2006, Pages 270-274

  Jasik, Agnieszka ^a   Reichert, Michal ^a  

^a NATIONAL VETERINARY RESEARCH INSTITUTE   (Poland)

Author keywords

Gene polymorphism; Sheep; Temperature gradient gel electrophoresis

Indexed keywords

OVIS ARIES;

EID: 33745034504     PISSN: 10406387     EISSN: None     Source Type: Journal    
DOI: 10.1177/104063870601800307     Document Type: Article

References (16)

1. Begara-Mcgorum I, Clark AM, Martin S, Jeffery M: 2000, Prevalence of vacuolar lesions consistent with scrapie in the brain of healthy cull sheep of the Shetland Islands. Vet Rec 147:439-441.
2. Benestad L, Sarradin P, Thu B, et al.: 2003, Cases of scrapie with unusual features in Norway and designation of a new-type, Nor98. Vet Rec 153:202-208.
3. Dawson M, Warner R, Nolan A, et al.: 2003, Complex PrP genotypes identified by the National Scrapie Plan. Vet Rec 152:754-755.
4. Elsen JM, Amigues Y, Schelcher F, et al.: 1999, Genetic susceptibility and transmission factors in scrapie: detailed analysis of an epidemic in a closed flock of Romanov. Arch Virol 144:431-445.
5. François D, Elsen JM, Barillet F, et al.: 2003, Breeding sheep for scrapie resistance. In: Breeding programmes for improving the quality and safety of products. New traits, tools, rules and organization? (Options Méditerranéennes: Série A), ed. Gabiña D, Sanna S, pp. 29-35. CIHEAM-IAMZ, Zaragoza. Spain.
6. Gombojav A, Ishiguro N, Horiuchi M, et al.: 2003, Amino acid polymorphisms of PrP gene in Mongolian sheep. J Vet Med Sci 65:75-81.
7. Horn D, Robinson PN, Böddrich A, et al.: 1996, Three novel mutations of the NF1 gene detected by temperature gradient gel electrophoresis of exons 5 and 8. Electrophoresis 17:1559-1563.
8. Hunter N, Moore L, Hosie BD, et al.: 1997, Association between natural scrapie and PrP genotype in a flock of Suffolk sheep in Scotland. Vet Rec 140:59-63.
9. Mashal RD, Sklar J: 1996, Practical methods of mutation detection. Curr Opinion Genet Develop 6:275-280.
10. Multinelli F, Aufiero GM, Pozzato N, et al.: 2003, Eradication of scrapie in a Massese sheep flock by PrP allele selection. Vet Rec 152:60.
11. O'Doherty E, Aherne M, Ennis S. et al.: 2000, Detection of polymorphisms in the prion protein gene in a population of Irish Suffolk sheep. Vet Rec 146:335-338.
12. Office for Official Publications of the European Communities. Commission Regulation (EC) No 999/2001 of 22 May. Official Journal L 147:1-61.
13. Schlötterer Ch: 1995, Temperature-gradient gel electrophoresis as a screening tool for polymorphisms in multigene families. Electrophoresis 16:722-728.
14. Tracikova L, Hanusovska E, Novak M, et al.: 2003, The PrP genotype of sheep of the improved Valachian breed. Folia Microbiol (Prague) 48:269-276.
15. Thorgeirsdottir S, Georgsson G, Reynisson E, et al.: 2002. Search for healthy carriers of scrapie: an assessment of subclinical infection of sheep in an Iceland scrapie flock by three diagnostic methods and correlation with PrP genotypes. Arch Virol 147:709-722.
16. Wartell RM, Hosseini S, Powell S, Zhu J: 1998, Detecting single base substitutions, mismatches and bulges in DNA by temperature gradient gel electrophoresis and related methods. J Chromatography A 806:169-185.