-
1
-
-
0042343801
-
Randomized Trial of Bevacizumab, an Anti-Vascular Endothelial Growth Factor Antibody, for Metastatic Renal Cancer
-
Yang, JC, Haworth, L, Sherry, RM, et al. Randomized Trial of Bevacizumab, an Anti-Vascular Endothelial Growth Factor Antibody, for Metastatic Renal Cancer. N Engl J Med 349 (2003), 427–434.
-
(2003)
N Engl J Med
, vol.349
, pp. 427-434
-
-
Yang, J.C.1
Haworth, L.2
Sherry, R.M.3
-
2
-
-
0037208589
-
Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer
-
Kabbinavar, F, Hurwitz, HI, Fehrenbacher, L, Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer. J Clin Oncol 21:1 (2003), 60–65.
-
(2003)
J Clin Oncol
, vol.21
, Issue.1
, pp. 60-65
-
-
Kabbinavar, F.1
Hurwitz, H.I.2
Fehrenbacher, L.3
-
3
-
-
33749505836
-
Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial
-
Demetri, GD, van Oosterom, AT, Garrett, CR, Blackstein, ME, Shah, MH, Verweij, J, et al. Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial. Lancet 368:9544 (2006), 1329–1338.
-
(2006)
Lancet
, vol.368
, Issue.9544
, pp. 1329-1338
-
-
Demetri, G.D.1
van Oosterom, A.T.2
Garrett, C.R.3
Blackstein, M.E.4
Shah, M.H.5
Verweij, J.6
-
4
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
Motzer, RJ, Hutson, TE, Tomczak, P, Michaelson, MD, Bukowski, RM, Rixe, O, et al. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 356:2 (2007 Jan 11), 115–124.
-
(2007)
N Engl J Med
, vol.356
, Issue.2
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
Michaelson, M.D.4
Bukowski, R.M.5
Rixe, O.6
-
5
-
-
39149120621
-
Multicenter, phase II trial of sunitinib in previously treated, advanced non-small cell lung cancer
-
Socinski, MA, Novello, S, Brahmer, JR, Rosell, R, Sanchez, JM, Belani, CP, et al. Multicenter, phase II trial of sunitinib in previously treated, advanced non-small cell lung cancer. J Clin Oncol 26:4 (2008), 650–656.
-
(2008)
J Clin Oncol
, vol.26
, Issue.4
, pp. 650-656
-
-
Socinski, M.A.1
Novello, S.2
Brahmer, J.R.3
Rosell, R.4
Sanchez, J.M.5
Belani, C.P.6
-
6
-
-
20044364346
-
Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer
-
Miller, KD, Chap, LI, Holmes, FA, et al. Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer. J Clin Oncol 23 (2005), 792–799.
-
(2005)
J Clin Oncol
, vol.23
, pp. 792-799
-
-
Miller, K.D.1
Chap, L.I.2
Holmes, F.A.3
-
7
-
-
85097042256
-
-
Roche: Avastin Summary of Product Characteristics.
-
Roche: Avastin Summary of Product Characteristics. 2005.
-
(2005)
-
-
-
8
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz, H, Fehrenbacher, L, Novotny, W, Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 350 (2004), 2335–2342.
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
9
-
-
20544471876
-
Combined analysis of efficacy: the addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer
-
Kabbinavar, FF, Hambleton, J, Mass, RD, Combined analysis of efficacy: the addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer. J Clin Oncol 23 (2005), 3706–3712.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3706-3712
-
-
Kabbinavar, F.F.1
Hambleton, J.2
Mass, R.D.3
-
10
-
-
33748752619
-
A phase II study of high-dose bevacizumab in combination with irinotecan, 5-fluorouracil, leucovorin, as initial therapy for advanced colorectal cancer: results from the Eastern Cooperative Oncology Group study E2200
-
Giantonio, BJ, Levy, DE, O'Dwyer, PJ, Meropol, NJ, Catalano, PJ, Benson, AB 3rd, Eastern Cooperative Oncology Group. A phase II study of high-dose bevacizumab in combination with irinotecan, 5-fluorouracil, leucovorin, as initial therapy for advanced colorectal cancer: results from the Eastern Cooperative Oncology Group study E2200. Ann Oncol 17:9 (2006 Sep), 1399–1403.
-
(2006)
Ann Oncol
, vol.17
, Issue.9
, pp. 1399-1403
-
-
Giantonio, B.J.1
Levy, D.E.2
O'Dwyer, P.J.3
Meropol, N.J.4
Catalano, P.J.5
Benson, A.B.6
-
11
-
-
34248173883
-
Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200
-
Giantonio, BJ, Catalano, PJ, Meropol, NJ, O'Dwyer, PJ, Mitchell, EP, Alberts, SR, et al., Eastern Cooperative Oncology Group Study E3200. Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol 25:12 (2007 Apr 20), 1539–1544.
-
(2007)
J Clin Oncol
, vol.25
, Issue.12
, pp. 1539-1544
-
-
Giantonio, B.J.1
Catalano, P.J.2
Meropol, N.J.3
O'Dwyer, P.J.4
Mitchell, E.P.5
Alberts, S.R.6
-
12
-
-
56749169353
-
Bevacizumab beyond first progression is associated with prolonged overall survival in metastatic colorectal cancer: results from a large observational cohort study (BRiTE)
-
Grothey, A, Sugrue, MM, Purdie, DM, Dong, W, Sargent, D, Hedrick, E, et al. Bevacizumab beyond first progression is associated with prolonged overall survival in metastatic colorectal cancer: results from a large observational cohort study (BRiTE). J Clin Oncol 26:33 (2008 Nov 20), 5326–5334.
-
(2008)
J Clin Oncol
, vol.26
, Issue.33
, pp. 5326-5334
-
-
Grothey, A.1
Sugrue, M.M.2
Purdie, D.M.3
Dong, W.4
Sargent, D.5
Hedrick, E.6
-
13
-
-
66149147757
-
Initial safety report of NSABP C-08: A randomized phase III study of modified FOLFOX6 with or without bevacizumab for the adjuvant treatment of patients with stage II or III colon cancer
-
Allegra, CJ, Yothers, G, O'Connell, MJ, Sharif, S, Colangelo, LH, Lopa, SH, et al. Initial safety report of NSABP C-08: A randomized phase III study of modified FOLFOX6 with or without bevacizumab for the adjuvant treatment of patients with stage II or III colon cancer. J Clin Oncol 27:20 (2009), 3385–3390.
-
(2009)
J Clin Oncol
, vol.27
, Issue.20
, pp. 3385-3390
-
-
Allegra, C.J.1
Yothers, G.2
O'Connell, M.J.3
Sharif, S.4
Colangelo, L.H.5
Lopa, S.H.6
-
14
-
-
33846629672
-
Multicenter phase II study of irinotecan, cisplatin, and bevacizumab in patients with metastatic gastric or gastroesophageal junction adenocarcinoma
-
Shah, MA, Ramanathan, RK, Ilson, DH, Levnor, A, D'Adamo, D, O'Reilly, E, et al. Multicenter phase II study of irinotecan, cisplatin, and bevacizumab in patients with metastatic gastric or gastroesophageal junction adenocarcinoma. J Clin Oncol 24:33 (2006 Nov 20), 5201–5206.
-
(2006)
J Clin Oncol
, vol.24
, Issue.33
, pp. 5201-5206
-
-
Shah, M.A.1
Ramanathan, R.K.2
Ilson, D.H.3
Levnor, A.4
D'Adamo, D.5
O'Reilly, E.6
-
15
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
Sandler, A, Gray, R, Perry, MC, et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 355 (2006), 2542–2550.
-
(2006)
N Engl J Med
, vol.355
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
-
16
-
-
34447130180
-
FDA drug approval summary: bevacizumab (Avastin) plus Carboplatin and Paclitaxel as first-line treatment of advancedmetastatic recurrent nonsquamous non-small cell lung cancer
-
Cohen, MH, Gootenberg, J, Keegan, P, Pazdur, R, FDA drug approval summary: bevacizumab (Avastin) plus Carboplatin and Paclitaxel as first-line treatment of advancedmetastatic recurrent nonsquamous non-small cell lung cancer. Oncologist 12:6 (2007 Jun), 713–718.
-
(2007)
Oncologist
, vol.12
, Issue.6
, pp. 713-718
-
-
Cohen, M.H.1
Gootenberg, J.2
Keegan, P.3
Pazdur, R.4
-
17
-
-
33947191055
-
Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma
-
Vredenburgh, JJ, Desjardins, A, Herndon, JE 2nd, Dowell, JM, Reardon, DA, Quinn, JA, et al. Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma. Clin Cancer Res 13:4 (2007 Feb 15), 1253–1259.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.4
, pp. 1253-1259
-
-
Vredenburgh, J.J.1
Desjardins, A.2
Herndon, J.E.3
Dowell, J.M.4
Reardon, D.A.5
Quinn, J.A.6
-
18
-
-
70350461699
-
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
-
Friedman, HS, Prados, MD, Wen, PY, Mikkelsen, T, Schiff, D, Abrey, LE, et al. Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma. J Clin Oncol 27:28 (2009 Oct 1), 4733–4740.
-
(2009)
J Clin Oncol
, vol.27
, Issue.28
, pp. 4733-4740
-
-
Friedman, H.S.1
Prados, M.D.2
Wen, P.Y.3
Mikkelsen, T.4
Schiff, D.5
Abrey, L.E.6
-
19
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
Escudier, B, Eisen, T, Stadler, WM, Szczylik, C, Oudard, S, Siebels, M, et al. Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med 356:2 (2007), 125–134.
-
(2007)
N Engl J Med
, vol.356
, Issue.2
, pp. 125-134
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
Szczylik, C.4
Oudard, S.5
Siebels, M.6
-
20
-
-
2942657615
-
Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer
-
Johnson, DH, Fehrenbacher, L, Novotny, WF, et al. Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer. J Clin Oncol 22 (2004), 2184–2191.
-
(2004)
J Clin Oncol
, vol.22
, pp. 2184-2191
-
-
Johnson, D.H.1
Fehrenbacher, L.2
Novotny, W.F.3
-
21
-
-
2942657615
-
Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer
-
Johnson, DH, Fehrenbacher, L, Novotny, WF, et al. Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer. J Clin Oncol 22 (2004), 2184–2191.
-
(2004)
J Clin Oncol
, vol.22
, pp. 2184-2191
-
-
Johnson, D.H.1
Fehrenbacher, L.2
Novotny, W.F.3
-
22
-
-
43049111427
-
Restrictive eligibility limits access to newer therapies in non-small-cell lung cancer: the implications of Eastern Cooperative Oncology Group 4599
-
Somer, RA, Sherman, E, Langer, CJ, Restrictive eligibility limits access to newer therapies in non-small-cell lung cancer: the implications of Eastern Cooperative Oncology Group 4599. Clin Lung Cancer 9:2 (2008), 102–105.
-
(2008)
Clin Lung Cancer
, vol.9
, Issue.2
, pp. 102-105
-
-
Somer, R.A.1
Sherman, E.2
Langer, C.J.3
-
23
-
-
63049122188
-
Retrospective evaluation of the clinical and radiographic risk factors associated with severe pulmonary hemorrhage in first-line advanced, unresectable non-small-cell lung cancer treated with Carboplatin and Paclitaxel plus bevacizumab
-
Sandler, AB, Schiller, JH, Gray, R, Dimery, I, Brahmer, J, Samant, M, et al. Retrospective evaluation of the clinical and radiographic risk factors associated with severe pulmonary hemorrhage in first-line advanced, unresectable non-small-cell lung cancer treated with Carboplatin and Paclitaxel plus bevacizumab. J Clin Oncol 27:9 (2009), 1405–1412.
-
(2009)
J Clin Oncol
, vol.27
, Issue.9
, pp. 1405-1412
-
-
Sandler, A.B.1
Schiller, J.H.2
Gray, R.3
Dimery, I.4
Brahmer, J.5
Samant, M.6
-
24
-
-
33846440150
-
Food and Drug Administration drug approval summary: Sunitinib malate for the treatment of gastrointestinal stromal tumor and advanced renal cell carcinoma
-
Rock, EP, Goodman, V, Jiang, JX, Mahjoob, K, Verbois, SL, Morse, D, et al. Food and Drug Administration drug approval summary: Sunitinib malate for the treatment of gastrointestinal stromal tumor and advanced renal cell carcinoma. Oncologist 12:1 (2007 Jan), 107–113.
-
(2007)
Oncologist
, vol.12
, Issue.1
, pp. 107-113
-
-
Rock, E.P.1
Goodman, V.2
Jiang, J.X.3
Mahjoob, K.4
Verbois, S.L.5
Morse, D.6
-
25
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
Escudier, B, Eisen, T, Stadler, WM, Szczylik, C, Oudard, S, Siebels, M, et al. Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med 356:2 (2007), 125–134.
-
(2007)
N Engl J Med
, vol.356
, Issue.2
, pp. 125-134
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
Szczylik, C.4
Oudard, S.5
Siebels, M.6
-
26
-
-
33744984843
-
Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma
-
Ratain, MJ, Eisen, T, Stadler, WM, Flaherty, KT, Kaye, SB, Rosner, GL, et al. Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma. J Clin Oncol 24:16 (2006), 2505–2512.
-
(2006)
J Clin Oncol
, vol.24
, Issue.16
, pp. 2505-2512
-
-
Ratain, M.J.1
Eisen, T.2
Stadler, W.M.3
Flaherty, K.T.4
Kaye, S.B.5
Rosner, G.L.6
-
27
-
-
31544460436
-
Phase I trial of sorafenib and gemcitabine in advanced solid tumors with an expanded cohort in advanced pancreatic cancer
-
Siu, LL, Awada, A, Takimoto, CH, Piccart, M, Schwartz, B, Giannaris, T, et al. Phase I trial of sorafenib and gemcitabine in advanced solid tumors with an expanded cohort in advanced pancreatic cancer. Clin Cancer Res 12:1 (2006 Jan 1), 144–151.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.1
, pp. 144-151
-
-
Siu, L.L.1
Awada, A.2
Takimoto, C.H.3
Piccart, M.4
Schwartz, B.5
Giannaris, T.6
-
28
-
-
0142121282
-
-
Bevacizumab, bleeding, thrombosis, and warfarin. J Clin Oncol;21(18):3542; author reply 3543.
-
Kilickap S, Abali H, Celik I. Bevacizumab, bleeding, thrombosis, and warfarin. J Clin Oncol;21(18):3542; author reply 3543.
-
-
-
Kilickap, S.1
Abali, H.2
Celik, I.3
-
29
-
-
3042548695
-
Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts
-
Inai, T, Mancuso, M, Hashizume, H, Baffert, F, Haskell, A, Baluk, P, et al. Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts. Am J Pathol 165:1 (2004), 35–52.
-
(2004)
Am J Pathol
, vol.165
, Issue.1
, pp. 35-52
-
-
Inai, T.1
Mancuso, M.2
Hashizume, H.3
Baffert, F.4
Haskell, A.5
Baluk, P.6
-
30
-
-
32944474182
-
VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature
-
Kamba, T, Tam, BY, Hashizume, H, Haskell, A, Sennino, B, Mancuso, MR, et al. VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature. Am J Physiol Heart Circ Physiol 290:2 (2006), H560–H576.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.290
, Issue.2
, pp. H560-H576
-
-
Kamba, T.1
Tam, B.Y.2
Hashizume, H.3
Haskell, A.4
Sennino, B.5
Mancuso, M.R.6
-
31
-
-
70449598259
-
Variable effects of alpha v suppression on VEGFR-2 expression in endothelial cells of different vascular beds
-
Dardik, R, Livnat, T, Seligsohn, U, Variable effects of alpha v suppression on VEGFR-2 expression in endothelial cells of different vascular beds. Thromb Haemost 102:5 (2009), 975–982.
-
(2009)
Thromb Haemost
, vol.102
, Issue.5
, pp. 975-982
-
-
Dardik, R.1
Livnat, T.2
Seligsohn, U.3
-
32
-
-
61649127110
-
Thrombosis associated with angiogenesis inhibitors
-
Elice, F, Rodeghiero, F, Falanga, A, Rickles, FR, Thrombosis associated with angiogenesis inhibitors. Best Pract Res Clin Haematol 22:1 (2009), 115–128.
-
(2009)
Best Pract Res Clin Haematol
, vol.22
, Issue.1
, pp. 115-128
-
-
Elice, F.1
Rodeghiero, F.2
Falanga, A.3
Rickles, F.R.4
-
33
-
-
55549105814
-
Hemostatic complications of angiogenesis inhibitors in cancer patients
-
Elice, F, Jacoub, J, Rickles, FR, Falanga, A, Rodeghiero, F, Hemostatic complications of angiogenesis inhibitors in cancer patients. Am J Hematol 83:11 (2008), 862–870.
-
(2008)
Am J Hematol
, vol.83
, Issue.11
, pp. 862-870
-
-
Elice, F.1
Jacoub, J.2
Rickles, F.R.3
Falanga, A.4
Rodeghiero, F.5
-
34
-
-
33645351051
-
Safety of low-dose aspirin (ASA) in a pooled analysis of 3 randomized, controlled trials (RCTs) of bevacizumab (BV) with chemotherapy (CT) in patients (pts) with metastatic colorectal cancer (mCRC)
-
(abstract 3554).
-
Hambleton, J, Skillings, J, Kabbinavar, F, Bergsland, E, Holmgren, E, Holden, SN, et al. Safety of low-dose aspirin (ASA) in a pooled analysis of 3 randomized, controlled trials (RCTs) of bevacizumab (BV) with chemotherapy (CT) in patients (pts) with metastatic colorectal cancer (mCRC). J Clin Oncol, 23(suppl), 2005, 259s (abstract 3554).
-
(2005)
J Clin Oncol
, vol.23
, pp. 259s
-
-
Hambleton, J.1
Skillings, J.2
Kabbinavar, F.3
Bergsland, E.4
Holmgren, E.5
Holden, S.N.6
-
35
-
-
18744380623
-
Bevacizumab does not increase bleeding in patients with metastatic colorectal cancer receiving concurrent anticoagulation
-
abstract 3528.
-
Hambleton, J, Novotny, WF, Hurwitz, H, Fehrenbacher, L, Cartwright, T, Hainsworth, J, et al. Bevacizumab does not increase bleeding in patients with metastatic colorectal cancer receiving concurrent anticoagulation. J Clin Oncol, 2(suppl), 2004 abstract 3528.
-
(2004)
J Clin Oncol
, vol.2
-
-
Hambleton, J.1
Novotny, W.F.2
Hurwitz, H.3
Fehrenbacher, L.4
Cartwright, T.5
Hainsworth, J.6
|