In situ artificial membrane permeation assay under hydrodynamic control: Permeability-ph profiles of warfarin and verapamil

Pharmaceutical Research

Volumn 27, Issue 8, 2010, Pages 1644-1658

  Velický, Matěj ^a   Bradley, Dan F ^a   Tam, Kin Y ^b   Dryfe, Robert A W ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

hydrodynamic control; in situ permeation; PAMPA; permeability; unstirred water layer

Indexed keywords

VERAPAMIL; WARFARIN; ANTICOAGULANT AGENT; ARTIFICIAL MEMBRANE; CALCIUM CHANNEL BLOCKING AGENT;

ARTICLE; ARTIFICIAL MEMBRANE; ASSAY; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; DIFFUSION; DRUG ABSORPTION; HYDRODYNAMICS; IN SITU ARTIFICIAL MEMBRANE PERMEATION ASSAY; LIPID MEMBRANE; LIPOPHILICITY; MEMBRANE MODEL; MEMBRANE PERMEABILITY; MEMBRANE STRUCTURE; PH; PRIORITY JOURNAL; ULTRAVIOLET SPECTROPHOTOMETRY; WATER PERMEABILITY; BIOLOGICAL MODEL; HUMAN; MICROFLUIDIC ANALYSIS; MICROFLUIDICS; PERMEABILITY; PROCEDURES; TIME;

ANTICOAGULANTS; CALCIUM CHANNEL BLOCKERS; HUMANS; HYDROGEN-ION CONCENTRATION; MEMBRANES, ARTIFICIAL; MICROFLUIDIC ANALYTICAL TECHNIQUES; MICROFLUIDICS; MODELS, BIOLOGICAL; PERMEABILITY; TIME FACTORS; VERAPAMIL; WARFARIN;

EID: 77955468068     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-010-0150-6     Document Type: Article

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