High-throughput lipophilicity measurement with immobilized artificial membranes

Journal of Medicinal Chemistry

Volumn 48, Issue 7, 2005, Pages 2571-2576

  Faller, Bernard ^a   Grimm, Hans Peter ^b   Loeuillet Ritzler, Frédérique ^a   Arnold, Sabine ^a   Briand, Xavier ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

^b GiMS mbH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMILORIDE; AMIODARONE; BENZOIC ACID; CHLORPROMAZINE; CLOZAPINE; DICLOFENAC; DILTIAZEM; FAMOTIDINE; FUROSEMIDE; GANCICLOVIR; HYDROCHLOROTHIAZIDE; KETOPROFEN; NICARDIPINE; NORTRIPTYLINE; OCTANOL; PENBUTOLOL; PROPRANOLOL; SULFAMETHIZOLE; TERFENADINE; VALSARTAN; WARFARIN; WATER;

ACCURACY; ARTICLE; ARTIFICIAL MEMBRANE; CALIBRATION; DIFFUSION COEFFICIENT; DRUG DETERMINATION; DRUG DIFFUSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMOBILIZATION; LIPOPHILICITY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MEMBRANE PERMEABILITY; PARTITION COEFFICIENT; PH; POROSITY; POTENTIOMETRY;

1-OCTANOL; ALGORITHMS; CHEMISTRY, PHYSICAL; DIFFUSION; DRUG DESIGN; KINETICS; MEMBRANES, ARTIFICIAL; PERMEABILITY; PHARMACEUTICAL PREPARATIONS; POROSITY; STRUCTURE-ACTIVITY RELATIONSHIP; WATER;

EID: 17144428075     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm049377w     Document Type: Article

References (23)

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