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note
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2 until TLC indicated the complete consumption of the starting material. The reaction mixture was cooled to rt and the mixture was filtered through a plug of silica gel. The evaporation of the solvent gave the desired product 1-methyl-tetralin A in >97% yield. The product was identified by NMR and MS analysis and the data are consistent with the reported values.
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77
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Synthesis
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77955431335
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note
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The pH value of the reaction system, at the beginning of the reaction, was measured to be around 6. However, it changed to 2 after one hour and remained around 2 afterward.
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