Indium-Catalyzed Addition of Active Methylene Compounds to 1-Alkynes

Journal of the American Chemical Society

Volumn 125, Issue 43, 2003, Pages 13002-13003

  Nakamura, Masaharu ^a   Endo, Kohei ^a   Nakamura, Eiichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYNE DERIVATIVE; CARBENE; INDIUM; PHENYLACETIC ACID;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; MOLECULAR INTERACTION; STEREOCHEMISTRY; STOICHIOMETRY;

EID: 0142183454     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja038006m     Document Type: Article

References (22)

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17. Zinc, copper, and lanthanoid triflate did not promote the coupling reaction under the same reaction conditions.
18. 3N and n-BuLi is unknown at this time. A large amount of uncharacterized side products formed without the bases.
19. 2 = H) and an alkyne gave the corresponding α-alkylidene compound due to transposition of the double bond after the C-C bond formation.
20. The alkyne substrates act as the trapping agent for TfOH and gives, upon hydrolysis, a corresponding ketone, such as acetophenone.
21. (a) Nakamura, E.; Miyachi, Y.; Koga, N.; Morokuma, K. J. Am. Chem. Soc. 1992, 114, 6686-6692.
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