Effect of metabolic and respiratory acidosis on intracellular calcium in osteoblasts

American Journal of Physiology - Renal Physiology

Volumn 299, Issue 2, 2010, Pages

  Frick, Kevin K ^a   Bushinsky, David A ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

OGR1; Proton

Indexed keywords

BICARBONATE; CALCIUM; CARBON DIOXIDE; PROTEIN OGR1; RECEPTOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE CELL; CALCIUM ABSORPTION; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM URINE LEVEL; CARBON DIOXIDE TENSION; CHO CELL; IN VIVO STUDY; METABOLIC ACIDOSIS; MOUSE; NEWBORN; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; PERFUSION; PH; PRIORITY JOURNAL; RESPIRATORY ACIDOSIS;

EID: 77955406117     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00136.2010     Document Type: Article

References (63)

1. Al-Hosney HA, Grassian VH. Carbonic acid: an important intermediate in the surface chemistry of calcium carbonate. J Am Chem Soc 126: 8068-8069, 2004.
2. Baudoiun-Legros M, Hamdaoui N, Borot F, Fritsch J, Ollero M, Planelles G, Edelman A. Control of basal CFTR gene expression by bicarbonate-sensitive adenylyl cyclase in human pulmonary cells. Cell Physiol Biochem 21: 75-86, 2008.
3. Bushinsky DA. Net proton influx into bone during metabolic, but not respiratory, acidosis. Am J Physiol Renal Fluid Electrolyte Physiol 254: F306-F310, 1988.
4. Bushinsky DA. Internal exchanges of hydrogen ions: bone. In: The Regulation of Acid-Base Balance, edited by Seldin DW and Giebisch G. New York: Raven, 1989, p. 69-88.
5. Bushinsky DA. Net calcium efflux from live bone during chronic metabolic, but not respiratory, acidosis. Am J Physiol Renal Fluid Electrolyte Physiol 256: F836-F842, 1989.
6. Bushinsky DA. Metabolic acidosis. In: The Principles and Practice of Nephrology, edited by Jacobson HR, Striker GE, and Klahr S. St. Louis, MO: Mosby, 1995, p. 924-932.
7. Bushinsky DA. Stimulated osteoclastic and suppressed osteoblastic activity in metabolic but not respiratory acidosis. Am J Physiol Cell Physiol 268: C80-C88, 1995.
8. Bushinsky DA. The contribution of acidosis to renal osteodystrophy. Kidney Int 47: 1816-1832, 1995.
9. Bushinsky DA. Metabolic alkalosis decreases bone calcium efflux by suppressing osteoclasts and stimulating osteoblasts. Am J Physiol Renal Fluid Electrolyte Physiol 271: F216-F222, 1996. (Pubitemid 26298897)
10. Bushinsky DA, Chabala JM, Gavrilov KL, Levi-Setti R. Effects of in vivo metabolic acidosis on midcortical bone ion composition. Am J Physiol Renal Physiol 277: F813-F819, 1999.
11. Bushinsky DA, Gavrilov K, Chabala JM, Featherstone JDB, Levi-Setti R. Effect of metabolic acidosis on the potassium content of bone. J Bone Miner Res 12: 1664-1671, 1997. (Pubitemid 27422367)
12. Bushinsky DA, Gavrilov K, Stathopoulos VM, Krieger NS, Chabala JM, Levi-Setti R. Effects of osteoclastic resorption on bone surface ion composition. Am J Physiol Cell Physiol 271: C1025-C1031, 1996.
13. Bushinsky DA, Goldring JM, Coe FL. Cellular contribution to pH-mediated calcium flux in neonatal mouse calvariae. Am J Physiol Renal Fluid Electrolyte Physiol 248: F785-F789, 1985.
14. Bushinsky DA, Krieger NS. Role of the skeleton in calcium homeostasis. In: The Kidney: Physiology and Pathophysiology, edited by Seldin DW and Giebisch G. New York: Raven, 1992, p. 2395-2430.
15. Bushinsky DA, Krieger NS, Geisser DI, Grossman EB, Coe FL. Effects of pH on bone calcium and proton fluxes in vitro. Am J Physiol Renal Fluid Electrolyte Physiol 245: F204-F209, 1983.
16. Bushinsky DA, Lam BC, Nespeca R, Sessler NE, Grynpas MD. Decreased bone carbonate content in response to metabolic, but not respiratory, acidosis. Am J Physiol Renal Fluid Electrolyte Physiol 265: F530-F536, 1993. (Pubitemid 23325871)
17. Bushinsky DA, Lechleider RJ. Mechanism of proton-induced bone calcium release: calcium carbonate dissolution. Am J Physiol Renal Fluid Electrolyte Physiol 253: F998-F1005, 1987.
18. Bushinsky DA, Levi-Setti R, Coe FL. Ion microprobe determination of bone surface elements: effects of reduced medium pH. Am J Physiol Renal Fluid Electrolyte Physiol 250: F1090-F1097, 1986.
19. Bushinsky DA, Nilsson EL. Additive effects of acidosis and parathyroid hormone on mouse osteoblastic and osteoclastic function. Am J Physiol Cell Physiol 269: C1364-C1370, 1995.
20. Bushinsky DA, Parker WR, Alexander KM, Krieger NS. Metabolic, but not respiratory, acidosis increases bone PGE2 levels and calcium release. Am J Physiol Renal Physiol 281: F1058-F1066, 2001. (Pubitemid 33776696)
21. Bushinsky DA, Sessler NE. Critical role of bicarbonate in calcium release from bone. Am J Physiol Renal Fluid Electrolyte Physiol 263: F510-F515, 1992.
22. Bushinsky DA, Sessler NE, Krieger NS. Greater unidirectional calcium efflux from bone during metabolic, compared with respiratory, acidosis. Am J Physiol Renal Fluid Electrolyte Physiol 262: F425-F431, 1992.
23. Bushinsky DA, Smith SB, Gavrilov KL, Gavrilov LF, Levi-Setti R. Chronic acidosis-induced alteration in bone bicarbonate and phosphate. Am J Physiol Renal Physiol 285: F532-F539, 2003.
24. Bushinsky DA, Smith SB, Gavrilov KL, Gavrilov LF, Li J, Levi-Setti R. Acute acidosis-induced alteration in bone bicarbonate and phosphate. Am J Physiol Renal Physiol 283: F1091-F1097, 2002.
25. Bushinsky DA, Wolbach W, Sessler NE, Mogilevsky R, Levi-Setti R. Physicochemical effects of acidosis on bone calcium flux and surface ion composition. J Bone Miner Res 8: 93-102, 1993. (Pubitemid 23034000)
26. Bushinsky DA. Acidosis and renal bone disease. In: The Spectrum of Mineral and Bone Disorder in Chronic Kidney Disease, edited by Olgaard K, Salusky IB, and Silver J. New York: Oxford Univ., 2010, in press.
27. Canzanello VJ, Bodvarsson M, Kraut JA, Johns CA, Slatopolsky E, Madias NE. Effect of chronic respiratory acidosis on urinary calcium excretion in the dog. Kidney Int 38: 409-416, 1990.
28. Centrella M, Casinghino S, McCarthy TL. Differential actions of prostaglandins in separate cell populations from fetal rat bone. Endocrinology 135: 1611-1620, 1994.
29. Chabala JM, Levi-Setti R, Bushinsky DA. Alteration in surface ion composition of cultured bone during metabolic, but not respiratory, acidosis. Am J Physiol Renal Fluid Electrolyte Physiol 261: F76-F84, 1991.
30. Fowler CJ, Tiger G. Calibration of Fura-2 signals introduces errors into measurement of thrombin-stimulated calcium mobilisation in human platelets. Clin Chim Acta 265: 247-261, 1997. (Pubitemid 27438283)
31. Frick KK, Bushinsky DA. Chronic metabolic acidosis reversibly inhibits extracellular matrix gene expression in mouse osteoblasts. Am J Physiol Renal Physiol 275: F840-F847, 1998. (Pubitemid 128731561)
32. Frick KK, Bushinsky DA. In vitro metabolic and respiratory acidosis selectively inhibit osteoblastic matrix gene expression. Am J Physiol Renal Physiol 277: F750-F755, 1999.
33. Frick KK, Bushinsky DA. Metabolic acidosis stimulates RANK ligand RNA expression in bone through a cyclooxygenase dependent mechanism. J Bone Miner Res 18: 1317-1325, 2003.
34. Frick KK, Jiang L, Bushinsky DA. Acute metabolic acidosis inhibits the induction of osteoblastic egr-1 and type 1 collagen. Am J Physiol Cell Physiol 272: C1450-C1456, 1997. (Pubitemid 127750717)
35. Frick KK, LaPlante K, Bushinsky DA. RANK ligand and TNF-α mediate acid-induced bone calcium efflux in vitro. Am J Physiol Renal Physiol 289: F1005-F1011, 2005.
36. Frick KK, Krieger NS, Nehrke K, Bushinsky DA. Metabolic acidosis increases intracellular calcium in bone cells through activation of the proton receptor OGR1. J Bone Miner Res 24: 305-313, 2009.
37. Geng W, Hill K, Zerwekh JE, Kohler T, Muller R, Moe OW. Inhibition of osteoclast formation and function by bicarbonate: role of soluble adenylyl cyclase. J Cell Physiol 220: 332-340, 2009.
38. + transport by soluble adenylyl cyclase in kidney collecting duct cells. J Biol Chem 284: 5774-5783, 2009.
39. Ho ML, Chang JK, Chuang LY, Hsu HK, Wang GJ. Effects of nonsteroidal anti-inflammatory drugs and prostaglandins on osteoblastic functions. Biochem Pharmacol 58: 983-990, 1999.
40. Ichikawa S, Koller D, Curry L, Lai D, Xuei X, Edenberg H, Hui S, Peacock M, Foroud T, Econs M. Association of adenylate cyclase 10 (ADCY10) polymorphisms and bone mineral density in healthy adults. Calcif Tissue Int 84: 97-102, 2009.
41. Ishii S, Kihara Y, Shimizu T. Identification of T cell death-associated gene 8 (TDAG8) as a novel acid sensing G protein-coupled receptor. J Biol Chem 280: 9083-9087, 2005.
42. Jehle S, Zanetti A, Muser J, Hulter HN, Krapf R. Partial neutralization of the acidogenic Western diet with potassium citrate increases bone mass in postmenopausal women with osteopenia. J Am Soc Nephrol 17: 3213-3222, 2006. (Pubitemid 44707783)
43. King-Smith C, Chen P, Garcia D, Rey H, Burnside B. Calcium-independent regulation of pigment granule aggregation and dispersion in teleost retinal pigment epithelial cells. J Cell Sci 109: 33-43, 1996.
44. Krieger NS. Demonstration of sodium/calcium exchange in rodent osteoblasts. J Bone Miner Res 7: 1105-1111, 1992.
45. Krieger NS, Frick KK, Bushinsky DA. Mechanism of acid-induced bone resorption. Curr Opin Nephrol Hypertens 13: 423-436, 2004.
46. Krieger NS, Hefley TJ. Differential effects of parathyroid hormone on protein phosphorylation in two osteoblast-like cell populations isolated from neonatal mouse calvaria. Calcif Tissue Int 44: 192-199, 1989.
47. Krieger NS, Parker WR, Alexander KM, Bushinsky DA. Prostaglandins regulate acid-induced cell-mediated bone resorption. Am J Physiol Renal Physiol 279: F1077-F1082, 2000.
48. Krieger NS, Sessler NE, Bushinsky DA. Acidosis inhibits osteoblastic and stimulates osteoclastic activity in vitro. Am J Physiol Renal Fluid Electrolyte Physiol 262: F442-F448, 1992.
49. Lau K, Rodriquez Nichols F, Tannen RL. Renal excretion of divalent ions in response to chronic acidosis: evidence that systemic pH is not the controlling variable. J Lab Clin Med 109: 27-33, 1987. (Pubitemid 17232239)
50. Lemann J Jr, Bushinsky DA, Hamm LL. Bone buffering of acid and base in humans. Am J Physiol Renal Physiol 285: F811-F832, 2003.
51. Ludwig MG, Vanek M, Gueirine D, Gasser JA, Jones CE, Junker U, Hofstetter H, Wolf RM, Seuwen K. Proton-sensing G protein-coupled receptors. Nature 425: 93-98, 2003.
52. Missner A, Pohl P. 110 Years of the Meyer-Overton rule: predicting membrane permeability of gases and other small compounds. Chemphyschem 10: 1405-1414, 2009.
53. Murakami N, Yokomizo T, Okuno T, Shimizu T. G2A is a proton-sensing G protein-coupled receptor antagonized by lysophosphatidylcholine. J Biol Chem 279: 42484-42491, 2004.
54. Nunes AR, Monteiro EC, Johnson SM, Gauda EB. Bicarbonate-regulated soluble adenylyl cyclase (sAC) mRNA expression and activity in peripheral chemoreceptors. Adv Exp Med Biol 648: 241, 2009.
55. Ori Y, Lee SG, Krieger NS, Bushinsky DA. Osteoblastic intracellular pH and calcium in metabolic and respiratory acidosis. Kidney Int 47: 1790-1796, 1995.
56. Paunescu TG, Ljubojevic M, Russo LM, Winter C, McLaughlin MM, Wagner CA, Breton S, Brown D. Cyclic AMP stimulates apical VATPase accumulation, microvillar elongation, and proton extrusion in kidney collecting duct A-intercalated cells. Am J Physiol Renal Physiol 298: F643-F654, 2010.
57. 2 fractions, calcium, and phosphorus during chronic hypercapnia. J Appl Physiol 48: 802-811, 1980.
58. Sprague SM, Krieger NS, Bushinsky DA. Greater inhibition of in vitro bone mineralization with metabolic than respiratory acidosis. Kidney Int 46: 1199-1206, 1994.
59. 2 inducible osteogenic colony forming units in cultures of cells isolated from the neonatal rat calvarium. J Cell Physiol 166: 76-83, 1996.
60. Townsend PD, Holliday PM, Fenyk S, Hess KC, Gray MA, Hodgson DRW, Cann MJ. Stimulation of mammalian G protein-responsive adenylyl cyclases by carbon dioxide. J Biol Chem 284: 784-791, 2009.
61. Tresguerres M, Parks SK, Salazar E, Levin LR, Goss GG, Buck J. Bicarbonate-sensing soluble adenylyl cyclase is an essential sensor for acid/base homeostasis. Proc Natl Acad Sci USA 107: 442-447, 2009.
62. Wang JQ, Kon J, Mogi C, Tobo M, Damirin A, Sato K, Komachi M, Malcinkhuu E, Murata N, Kimura T, Kuwabara A, Wakamatsu K, Koizumi H, Ueda T, Tsujimoto G, Kurose H, Sato T, Harada A, Misawa N, Tomura H, Okajima F. TDAG8 is a proton-sensing and psychosine-sensitive G protein-coupled receptor. J Biol Chem 279: 45626-45633, 2004.
63. Yamaguchi DT, Hahn TJ, Iida-Klein A, Kleeman CR, Muallem S. Parathyroid hormone-activated calcium channels in an osteoblast-like clonal osteosarcoma cell line. cAMP-dependent and cAMP-independent calcium channels. J Biol Chem 262: 7711-7718, 1987. (Pubitemid 17103903)