Increased β-cell mass by islet transplantation and PLAG1 overexpression causes hyperinsulinemic normoglycemia and hepatic insulin resistance in mice

Diabetes

Volumn 59, Issue 8, 2010, Pages 1957-1965

  Declercq, Jeroen ^a   Kumar, Anujith ^a   Van Diepen, Janna A ^b   Vroegrijk, Irene O C M ^b   Gysemans, Conny ^a   Di Pietro, Caterina ^a   Voshol, Peter J ^b,d   Mathieu, Chantal ^a   Ectors, Nadine ^c   Van De Ven, Wim J M ^a   Verfaillie, Catherine M ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^d Metabolic Research Laboratories   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CONTROLLED STUDY; GENE; GLUCOSE HOMEOSTASIS; HORMONAL REGULATION; HYPERINSULINEMIA; IMMUNOHISTOCHEMISTRY; INSULIN RESISTANCE; INSULIN SYNTHESIS; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET TRANSPLANTATION; PLAG1 GENE; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMALS; BLOOD GLUCOSE; CELL DIVISION; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GLUCAGON; GLUCOSE CLAMP TECHNIQUE; GLUCOSE TOLERANCE TEST; HOMEOSTASIS; HYPERINSULINISM; INSULIN; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS TRANSPLANTATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC;

EID: 77955396609     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db09-1446     Document Type: Article

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