Hepatic insulin resistance after pancreas transplantation in type I diabetes

Diabetes

Volumn 45, Issue 2, 1996, Pages 134-138

  Rooney, Desmond P ^a   Robertson, R Paul ^a,b  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; DISEASE CLASSIFICATION; FEMALE; GLUCAGON BLOOD LEVEL; GLUCOSE CLAMP TECHNIQUE; HORMONAL REGULATION; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN METABOLISM; INSULIN RESISTANCE; MALE; PANCREAS TRANSPLANTATION; PREDICTION; PRIORITY JOURNAL;

EID: 0030042092     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.45.2.134     Document Type: Article

References (24)

1. Sutherland DER: Pancreas transplantation: state of the art. Trans Proc 24:762-766, 1992
2. Robertson RP: Pancreas and islet transplantation for diabetes: cures or curiosities? N Engl J Med 327:1861-1868, 1992
3. Robertson RP, Diem P, Sutherland DER: Time-related, cross-sectional and prospective follow-up of pancreatic endocrine function after pancreas allograft transplantation in type 1 insulin-dependent diabetic patients. Diabetologia 34 (Suppl. 1):S57-S60, 1991
4. Luzi L, Secchi A, Facchini F, Battezatti A, Staudacher C, Spotti D, Castoldi R, Ferrari G, Carlo VD, Pozza G: Reduction of insulin resistance by combined kidney-pancreas transplantation in type 1 (insulin-dependent) diabetic patients. Diabetologia 33:549-556, 1990
5. Saudek F, Pelkanova T, Bartos V, Reneltova I, Kazdova L, Kovar J, Karasova L: Insulin action and insulin binding following pancreas transplantation Diabetologia 34 (Suppl. 1):S71-S75, 1991
6. Osei K, Cottrell DA, Henry ML, Tesi RJ, Ferguson RM, O'Dorisio TM: Insulin insensitivity and glucose effectiveness in type 1 diabetic allograft pancreas recipients. Trans Proc 24:828-830, 1992
7. Boden G, Chen X, Ruiz J, Heifets M, Morris M, Badosa F. Insulin receptor down-regulation and impaired antilipolytic action of insulin in diabetic patients after pancreas/kidney transplantation. J Clin Endocrinol Metab 78:657-663, 1994
8. Diem P, Abid M, Redmon JB, Sutherland DER, Robertson RP: Systemic-venous drainage of pancreas allografts as independent cause of hyperinsulinemia in type 1 diabetic recipients. Diabetes 39:534-540, 1990
9. McMahon M, Gerich J, Rizza R: Effects of glucocorticoids on carbohydrate metabolism. Diabetes Metab Rev 4:17-30, 1988
10. Homan M, Nicholson CP, Katz H, Perkins J, Haymond M, Jensen M, Butler P, Rizza R. Effects of chronic systemic insulin delivery on insulin action in dogs. Diabetologia 34:702-708, 1991
11. Rizza RA, Mandarino LJ, Gerich JE: Dose-response characteristics for effects of insulin on production and utilization of glucose in man Am J Physiol 240:E630-EG39, 1981
12. Consoli A, Nurjhan N, Capani F, Gerich J: Predominant role of glucone-ogenesis in increased hepatic glucose production in NIDDM. Diabetes 38:550-557, 1989
13. Firth RG, Bell PM, Marsh HM, Hansen I, Rizza RA: Postprandial hyperglycemia in patients with non-insulin-dependent diabetes mellitus: role of hepatic and extra hepatic tissues. J Clin Invest 77:1525-1532, 1986
14. Seaquist ER, Pyzdrowski K, Moran A, Teuscher AU, Robertson RP: Insulin-mediated and glucose-mediated glucose uptake following hemipancreatectomy in healthy human donors. Diabetologia 37:1036-1043, 1994
15. Somogyi M: Determination of blood sugar J Biol Chem 160:69-73, 1945
16. Teuscher AU, Seaquist ER, Robertson RP: Diminished insulin secretory reserve in diabetic pancreas transplant and nondiabetic kidney transplant recipients. Diabetes 43:593-598, 1994
17. Steele R, Wall JS, De Bodo RC, Altszuler N Measurement of size and turnover rate of body glucose pool by the isotope dilution method. Am J Physiol 187:15-25, 1956
18. 14 glucose. Rec Prog Horm Res 19:445-448, 1963
19. Eigler N, Sacca L, Sherwin RS: Synergistic interactions of physiologic increments of glucagon, epinephrine, and cortisol in the dog. J Clin Invest 63,114-123, 1979
20. Horwitz DL, Starr JI, Mako ME, Blackard WG, Rubenstein AH: Proinsulin, insulin, and C-peptide concentrations in human portal and peripheral blood J Clin Invest 55:1278-1283. 1975
21. 3H]glucose J Clin Invest 78 1479-1486, 1986
22. Williamson JR, Kreisberg RA, Felts PW: Mechanism for the stimulation of gluconeogenesis by fatty acids in perfused rat liver. Proc Natl Acad Sci USA 50:247-254, 1966
23. Katz H, Homan M, Velosa J, Robertson RP, Rizza R Effects of pancreas transplantation on postprandial glucose metabolism. N Engl J Med 325.1278-1283, 1991
24. Baron AD, Kolterman OG, Bell J, Mandarino LI, Olefsky JM: Rates of non-insulin-mediated glucose uptake are elevated in type II diabetic-subjects J Clin Invest 76:1782-1788, 1985