-
1
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov R, Preston-Hurlburt P, Janeway CA, Jr. (1997) A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388(6640): 394-7.
-
(1997)
Nature
, vol.388
, Issue.6640
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway Jr., C.A.3
-
2
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak A, He X, Smirnova I, Liu MY, Van Huffel C, et al. (1998) Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282(5396): 2085-8.
-
(1998)
Science
, vol.282
, Issue.5396
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
van Huffel, C.5
-
3
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira S, Uematsu S, Takeuchi O (2006) Pathogen recognition and innate immunity. Cell 124(4): 783-801.
-
(2006)
Cell
, vol.124
, Issue.4
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
4
-
-
5444262511
-
Toll-like receptor control of the adaptive immune responses
-
Iwasaki A, Medzhitov R (2004) Toll-like receptor control of the adaptive immune responses. Nat Immunol 5(10): 987-95.
-
(2004)
Nat Immunol
, vol.5
, Issue.10
, pp. 987-995
-
-
Iwasaki, A.1
Medzhitov, R.2
-
5
-
-
35349016235
-
Recognition of microorganisms and activation of the immune response
-
Medzhitov R (2007) Recognition of microorganisms and activation of the immune response. Nature 449(7164): 819-26.
-
(2007)
Nature
, vol.449
, Issue.7164
, pp. 819-826
-
-
Medzhitov, R.1
-
6
-
-
0037061453
-
Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
-
Leadbetter EA, Rifkin IR, Hohlbaum AM, Beaudette BC, Shlomchik MJ, et al. (2002) Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature 416(6881): 603-7.
-
(2002)
Nature
, vol.416
, Issue.6881
, pp. 603-607
-
-
Leadbetter, E.A.1
Rifkin, I.R.2
Hohlbaum, A.M.3
Beaudette, B.C.4
Shlomchik, M.J.5
-
7
-
-
2642528779
-
Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG
-
Lovgren T, Eloranta ML, Bave U, Alm GV, Ronnblom L (2004) Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG. Arthritis Rheum 50(6): 1861-72.
-
(2004)
Arthritis Rheum
, vol.50
, Issue.6
, pp. 1861-1872
-
-
Lovgren, T.1
Eloranta, M.L.2
Bave, U.3
Alm, G.V.4
Ronnblom, L.5
-
8
-
-
0019972228
-
Systemic lupus erythematosus: Presence in human serum of an unusual acid-labile leukocyte interferon
-
Preble OT, Black RJ, Friedman RM, Klippel JH, Vilcek J (1982) Systemic lupus erythematosus: presence in human serum of an unusual acid-labile leukocyte interferon. Science 216(4544): 429-31.
-
(1982)
Science
, vol.216
, Issue.4544
, pp. 429-431
-
-
Preble, O.T.1
Black, R.J.2
Friedman, R.M.3
Klippel, J.H.4
Vilcek, J.5
-
9
-
-
33748472865
-
Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus
-
Christensen SR, Shupe J, Nickerson K, Kashgarian M, Flavell R A, et al. (2006) Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus. Immunity 25(3): 417-28.
-
(2006)
Immunity
, vol.25
, Issue.3
, pp. 417-428
-
-
Christensen, S.R.1
Shupe, J.2
Nickerson, K.3
Kashgarian, M.4
Flavell, R.A.5
-
10
-
-
33750369226
-
Toll-like receptors in systemic autoimmune disease
-
Marshak-Rothstein A (2006) Toll-like receptors in systemic autoimmune disease. Nat Rev Immunol 6(11): 823-35.
-
(2006)
Nat Rev Immunol
, vol.6
, Issue.11
, pp. 823-835
-
-
Marshak-Rothstein, A.1
-
11
-
-
71849117626
-
Inhibitors of TLR8 reduce TNF production from human rheumatoid synovial membrane cultures
-
Sacre SM, Lo A, Gregory B, Simmonds RE, Williams L, Feldmann M, et al. (2008) Inhibitors of TLR8 reduce TNF production from human rheumatoid synovial membrane cultures. J Immunol 181(11): 8002-9.
-
(2008)
J Immunol
, vol.181
, Issue.11
, pp. 8002-8009
-
-
Sacre, S.M.1
Lo, A.2
Gregory, B.3
Simmonds, R.E.4
Williams, L.5
Feldmann, M.6
-
12
-
-
33646882893
-
Identification of small heat shock protein B8 (HSP22) as a novel TLR4 ligand and potential involvement in the pathogenesis of rheumatoid arthritis
-
Roelofs MF, Boelens WC, Joosten LA, Abdollahi-Roodsaz S, Geurts J, et al. (2006) Identification of small heat shock protein B8 (HSP22) as a novel TLR4 ligand and potential involvement in the pathogenesis of rheumatoid arthritis. J Immunol 176(11): 7021-7.
-
(2006)
J Immunol
, vol.176
, Issue.11
, pp. 7021-7027
-
-
Roelofs, M.F.1
Boelens, W.C.2
Joosten, L.A.3
Abdollahi-Roodsaz, S.4
Geurts, J.5
-
13
-
-
33846208784
-
Age-associated defect in human TLR-1/2 function
-
van Duin D, Mohanty S, Thomas V, Ginter S, Montgomery RR, et al. (2007) Age-associated defect in human TLR-1/2 function. J Immunol 178(2): 970-5.
-
(2007)
J Immunol
, vol.178
, Issue.2
, pp. 970-975
-
-
van Duin, D.1
Mohanty, S.2
Thomas, V.3
Ginter, S.4
Montgomery, R.R.5
-
14
-
-
0036344106
-
Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1-and TLR2-deficient mice
-
Alexopoulou L, Thomas V, Schnare M, Lobet Y, Anguita J, et al. (2002) Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1-and TLR2-deficient mice. Nat Med 8(8): 878-84.
-
(2002)
Nat Med
, vol.8
, Issue.8
, pp. 878-884
-
-
Alexopoulou, L.1
Thomas, V.2
Schnare, M.3
Lobet, Y.4
Anguita, J.5
-
15
-
-
47749112908
-
Dysregulation of TLR3 impairs the innate immune response to West Nile virus in the elderly
-
Kong KF, Delroux K, Wang X, Qian F, Arjona A, et al. (2008) Dysregulation of TLR3 impairs the innate immune response to West Nile virus in the elderly. J Virol 82(15): 7613-23.
-
(2008)
J Virol
, vol.82
, Issue.15
, pp. 7613-7623
-
-
Kong, K.F.1
Delroux, K.2
Wang, X.3
Qian, F.4
Arjona, A.5
-
16
-
-
26444448943
-
Role for macrophage migration inhibitory factor in asthma
-
Mizue Y, Ghani S, Leng L, McDonald C, Kong P, et al. (2005) Role for macrophage migration inhibitory factor in asthma. Proc Natl Acad Sci USA 102(40): 14410-5.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.40
, pp. 14410-14415
-
-
Mizue, Y.1
Ghani, S.2
Leng, L.3
McDonald, C.4
Kong, P.5
-
18
-
-
0020333131
-
Random-effects models for longitudinal data
-
Laird NM, Ware JH (1982) Random-effects models for longitudinal data. Biometrics; 38: 963-974.
-
(1982)
Biometrics
, vol.38
, pp. 963-974
-
-
Laird, N.M.1
Ware, J.H.2
-
19
-
-
0003526944
-
-
G. Verbeke and G. Molenberghs, Editors. Springer, New York
-
Verbeke G, Molenberghs G (1997) Linear mixed models in practice, in A SAS oriented approach, G. Verbeke and G. Molenberghs, Editors. Springer, New York.
-
(1997)
Linear Mixed Models In Practice, In a SAS Oriented Approach
-
-
Verbeke, G.1
Molenberghs, G.2
-
20
-
-
85047692516
-
Signalling pathways of the TNF superfamily: A doubleedged sword
-
Aggarwal BB (2003) Signalling pathways of the TNF superfamily: a doubleedged sword. Nat Rev Immunol 3(9): 745-56.
-
(2003)
Nat Rev Immunol
, vol.3
, Issue.9
, pp. 745-756
-
-
Aggarwal, B.B.1
-
21
-
-
0036776560
-
Activation of terminally differentiated human monocytes/macrophages by dengue virus: Productive infection, hierarchical production of innate cytokines and chemokines, and the synergistic effect of lipopolysaccharide
-
Chen YC, Wang SY (2002) Activation of terminally differentiated human monocytes/macrophages by dengue virus: productive infection, hierarchical production of innate cytokines and chemokines, and the synergistic effect of lipopolysaccharide. J Virol 76(19): 9877-87.
-
(2002)
J Virol
, vol.76
, Issue.19
, pp. 9877-9887
-
-
Chen, Y.C.1
Wang, S.Y.2
-
22
-
-
0036561069
-
A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis
-
Baugh JA, Chitnis S, Donnelly SC, Monteiro J, Lin X, et al. (2002) A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis. Genes Immun 3(3): 170-6.
-
(2002)
Genes Immun
, vol.3
, Issue.3
, pp. 170-176
-
-
Baugh, J.A.1
Chitnis, S.2
Donnelly, S.C.3
Monteiro, J.4
Lin, X.5
-
23
-
-
33646582629
-
Association of macrophage migration inhibitory factor gene -173 G/C polymorphism with prognosis in Turkish children with juvenile rheumatoid arthritis
-
Berdeli A, Ozyurek AR, Ulger Z, Gurses D, Levent E, et al. (2006) Association of macrophage migration inhibitory factor gene -173 G/C polymorphism with prognosis in Turkish children with juvenile rheumatoid arthritis. Rheumatol Int 26(8): 726-31.
-
(2006)
Rheumatol Int
, vol.26
, Issue.8
, pp. 726-731
-
-
Berdeli, A.1
Ozyurek, A.R.2
Ulger, Z.3
Gurses, D.4
Levent, E.5
-
24
-
-
34248639550
-
Macrophage migration inhibitory factor upregulates angiogenic factors and correlates with clinical measures in rheumatoid arthritis
-
Kim HR, Park MK, Cho ML, Yoon CH, Lee SH, et al. (2007) Macrophage migration inhibitory factor upregulates angiogenic factors and correlates with clinical measures in rheumatoid arthritis. J Rheumatol 34(5): 927-36.
-
(2007)
J Rheumatol
, vol.34
, Issue.5
, pp. 927-936
-
-
Kim, H.R.1
Park, M.K.2
Cho, M.L.3
Yoon, C.H.4
Lee, S.H.5
-
25
-
-
34548475357
-
Macrophage migration inhibitory factor gene: Influence on rheumatoid arthritis susceptibility
-
Martinez A, Orozco G, Varade J, Sanchez Lopez M, Pascual D, et al. (2007) Macrophage migration inhibitory factor gene: influence on rheumatoid arthritis susceptibility. Hum Immunol 68(9): 744-7.
-
(2007)
Hum Immunol
, vol.68
, Issue.9
, pp. 744-747
-
-
Martinez, A.1
Orozco, G.2
Varade, J.3
Sanchez, L.M.4
Pascual, D.5
-
26
-
-
0036260373
-
Macrophage migration inhibitory factor in rheumatoid arthritis: Clinical correlations
-
Morand EF, Leech M, Weedon H, Metz C, Bucala R, et al. (2002) Macrophage migration inhibitory factor in rheumatoid arthritis: clinical correlations. Rheumatology (Oxford) 41(5): 558-62.
-
(2002)
Rheumatology (Oxford)
, vol.41
, Issue.5
, pp. 558-562
-
-
Morand, E.F.1
Leech, M.2
Weedon, H.3
Metz, C.4
Bucala, R.5
-
27
-
-
0042329644
-
Infectious complications in SLE after immunosuppressive therapies
-
Kang I, Park SH (2003) Infectious complications in SLE after immunosuppressive therapies. Curr Opin Rheumatol 15(5): 528-34.
-
(2003)
Curr Opin Rheumatol
, vol.15
, Issue.5
, pp. 528-534
-
-
Kang, I.1
Park, S.H.2
-
28
-
-
34147224052
-
Risk and predictors of infection leading to hospitalisation in a large primary-care-derived cohort of patients with inflammatory polyarthritis
-
Franklin J, Lunt M, Bunn D, Symmons D, Silman A (2007) Risk and predictors of infection leading to hospitalisation in a large primary-care-derived cohort of patients with inflammatory polyarthritis. Ann Rheum Dis 66(3): 308-12.
-
(2007)
Ann Rheum Dis
, vol.66
, Issue.3
, pp. 308-312
-
-
Franklin, J.1
Lunt, M.2
Bunn, D.3
Symmons, D.4
Silman, A.5
-
29
-
-
0035924325
-
MIF regulates innate immune responses through modulation of Toll-like receptor 4
-
Roger T, David J, Glauser MP, Calandra T (2001) MIF regulates innate immune responses through modulation of Toll-like receptor 4. Nature 414(6866): 920-4.
-
(2001)
Nature
, vol.414
, Issue.6866
, pp. 920-924
-
-
Roger, T.1
David, J.2
Glauser, M.P.3
Calandra, T.4
-
30
-
-
0038627759
-
Macrophage migration inhibitory factor (MIF) regulates host responses to endotoxin through modulation of Toll-like receptor 4 (TLR4)
-
Roger T, Froidevaux C, Martin C, Calandra T (2003) Macrophage migration inhibitory factor (MIF) regulates host responses to endotoxin through modulation of Toll-like receptor 4 (TLR4). J Endotoxin Res 9(2): 119-23.
-
(2003)
J Endotoxin Res
, vol.9
, Issue.2
, pp. 119-123
-
-
Roger, T.1
Froidevaux, C.2
Martin, C.3
Calandra, T.4
-
31
-
-
0028305693
-
The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor
-
Calandra T, Bernhagen J, Mitchell RA, Bucala R (1994) The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor. J Exp Med 179(6): 1895-902.
-
(1994)
J Exp Med
, vol.179
, Issue.6
, pp. 1895-1902
-
-
Calandra, T.1
Bernhagen, J.2
Mitchell, R.A.3
Bucala, R.4
-
32
-
-
0034614492
-
Macrophage migration inhibitory factor up-regulates expression of matrix metalloproteinases in synovial fibroblasts of rheumatoid arthritis
-
Onodera S, Kaneda K, Mizue Y, Koyama Y, Fujinaga M, et al. (2000) Macrophage migration inhibitory factor up-regulates expression of matrix metalloproteinases in synovial fibroblasts of rheumatoid arthritis. J Biol Chem 275(1): 444-50.
-
(2000)
J Biol Chem
, vol.275
, Issue.1
, pp. 444-450
-
-
Onodera, S.1
Kaneda, K.2
Mizue, Y.3
Koyama, Y.4
Fujinaga, M.5
-
33
-
-
0034971443
-
Regulation of synoviocyte phospholipase A2 and cyclooxygenase 2 by macrophage migration inhibitory factor
-
Sampey AV, Hall PH, Mitchell RA, Metz CN, Morand EF (2001) Regulation of synoviocyte phospholipase A2 and cyclooxygenase 2 by macrophage migration inhibitory factor. Arthritis Rheum 44(6): 1273-80.
-
(2001)
Arthritis Rheum
, vol.44
, Issue.6
, pp. 1273-1280
-
-
Sampey, A.V.1
Hall, P.H.2
Mitchell, R.A.3
Metz, C.N.4
Morand, E.F.5
-
34
-
-
0038681576
-
Regulation of p53 by macrophage migration inhibitory factor in inflammatory arthritis
-
Leech M, Lacey D, Xue JR, Santos L, Hutchinson P, et al. (2003) Regulation of p53 by macrophage migration inhibitory factor in inflammatory arthritis. Arthritis Rheum 48(7): 1881-9.
-
(2003)
Arthritis Rheum
, vol.48
, Issue.7
, pp. 1881-1889
-
-
Leech, M.1
Lacey, D.2
Xue, J.R.3
Santos, L.4
Hutchinson, P.5
-
35
-
-
26844555755
-
Correlation of rheumatoid arthritis severity with the genetic functional variants and circulating levels of macrophage migration inhibitory factor
-
Radstake TR, Sweep FC, Welsing P, Franke B, Vermeulen SH, et al. (2005) Correlation of rheumatoid arthritis severity with the genetic functional variants and circulating levels of macrophage migration inhibitory factor. Arthritis Rheum 52(10): 3020-9.
-
(2005)
Arthritis Rheum
, vol.52
, Issue.10
, pp. 3020-3029
-
-
Radstake, T.R.1
Sweep, F.C.2
Welsing, P.3
Franke, B.4
Vermeulen, S.H.5
|