Global gene expression analysis on the target genes of PQS and HHQ in J774A.1 monocyte/macrophage cells

Microbial Pathogenesis

Volumn 49, Issue 4, 2010, Pages 174-180

  Kim, Kiwan ^a   Kim, Seol Hee ^a   Lépine, Francois ^b   Cho, You Hee ^a   Lee, Gap Ryol ^a  

^a Sogang University   (South Korea)

^b INRS INSTITUT ARMAND FRAPPIER   (Canada)

Author keywords

HHQ; Macrophage activation; Microarray; PQS; Pseudomonas aeruginosa

Indexed keywords

2 HEPTYL 3,4 DIHYDROXYQUINOLINE; 4 HYDROXY 2 HEPTYLQUINOLINE; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CCR9; CHLORIDE CHANNEL; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; HISTONE DEACETYLASE 7; HOMEODOMAIN PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 5; INTERLEUKIN 6; JANUS KINASE 1; LIPOPOLYSACCHARIDE; MINICHROMOSOME MAINTENANCE PROTEIN; NETRIN 1; NITRIC OXIDE; PARATHYROID HORMONE RELATED PROTEIN; PROGRAMMED DEATH 1 LIGAND 1; PROLINE RICH PROTEIN; QUINOLINE DERIVATIVE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SEMAPHORIN; SEMAPHORIN 7A; SERINE PROTEINASE; SOS PROTEIN; SYNDECAN 2; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL LINE; CELL STRUCTURE; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; GENE EXPRESSION PROFILING; GENE TARGETING; GENETIC REGULATION; GENETIC TRANSCRIPTION; HOST CELL; HOST RESISTANCE; IMMUNE RESPONSE; IMMUNE SYSTEM; MACROPHAGE; MACROPHAGE ACTIVATION; MONOCYTE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UNINDEXED SEQUENCE;

ANIMALS; GENE EXPRESSION REGULATION; HYDROQUINONES; IMMUNOLOGIC FACTORS; MACROPHAGES; MICE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PSEUDOMONAS AERUGINOSA; QUINOLONES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

PSEUDOMONAS AERUGINOSA;

EID: 77955268367     PISSN: 08824010     EISSN: 10961208     Source Type: Journal    
DOI: 10.1016/j.micpath.2010.05.009     Document Type: Article

References (24)

1. Rello J., Diaz E. Pneumonia in the intensive care unit. Crit Care Med 2003, 31:2544-2551.
2. Chastre J., Fagon J.Y. Ventilator-associated pneumonia. Am J Respir Crit Care Med 2002, 165:867-903.
3. Diggle S.P., Cornelis P., Williams P., Camara M. 4-quinolone signalling in Pseudomonas aeruginosa: old molecules, new perspectives. Int J Med Microbiol 2006, 296:83-91.
4. Gallagher L.A., McKnight S.L., Kuznetsova M.S., Pesci E.C., Manoil C. Functions required for extracellular quinolone signaling by Pseudomonas aeruginosa. J Bacteriol 2002, 184:6472-6480.
5. Deziel E., Lepine F., Milot S., He J., Mindrinos M.N., Tompkins R.G., et al. Analysis of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) reveals a role for 4-hydroxy-2-heptylquinoline in cell-to-cell communication. Proc Natl Acad Sci U S A 2004, 101:1339-1344.
6. Lepine F., Milot S., Deziel E., He J., Rahme L.G. Electrospray/mass spectrometric identification and analysis of 4-hydroxy-2-alkylquinolines (HAQs) produced by Pseudomonas aeruginosa. J Am Soc Mass Spectrom 2004, 15:862-869.
7. Hooi D.S., Bycroft B.W., Chhabra S.R., Williams P., Pritchard D.I. Differential immune modulatory activity of Pseudomonas aeruginosa quorum-sensing signal molecules. Infect Immun 2004, 72:6463-6470.
8. Skindersoe M.E., Zeuthen L.H., Brix S., Fink L.N., Lazenby J., Whittall C., et al. Pseudomonas aeruginosa quorum-sensing signal molecules interfere with dendritic cell-induced T-cell proliferation. FEMS Immunol Med Microbiol 2009, 55:335-345.
9. Kim K., Kim Y.U., Koh B.H., Hwang S.S., Kim S.H., Lepine F., et al. HHQ and PQS, two Pseudomonas aeruginosa quorum-sensing molecules, down-regulate the innate immune responses through the nuclear factor-kappaB pathway. Immunology 2010, 129:578-588.
10. Verschueren K., Remacle J.E., Collart C., Kraft H., Baker B.S., Tylzanowski P., et al. SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5'-CACCT sequences in candidate target genes. J Biol Chem 1999, 274:20489-20498.
11. Comijn J., Berx G., Vermassen P., Verschueren K., van Grunsven L., Bruyneel E., et al. The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion. Mol Cell 2001, 7:1267-1278.
12. Park S.M., Gaur A.B., Lengyel E., Peter M.E. The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev 2008, 22:894-907.
13. Katoh M. Integrative genomic analyses of ZEB2: transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB. Int J Oncol 2009, 34:1737-1742.
14. Plath K., Mlynarczyk-Evans S., Nusinow D.A., Panning B. Xist RNA and the mechanism of X chromosome inactivation. Annu Rev Genet 2002, 36:233-278.
15. Kelsey G. Epigenetics and imprinted genes: insights from the imprinted Gnas locus. Horm Res 2009, 71(Suppl. 2):22-29.
16. Sha K. A mechanistic view of genomic imprinting. Annu Rev Genomics Hum Genet 2008, 9:197-216.
17. Serizawa S., Miyamichi K., Sakano H. One neuron-one receptor rule in the mouse olfactory system. Trends Genet 2004, 20:648-653.
18. Alexander M.K., Mlynarczyk-Evans S., Royce-Tolland M., Plocik A., Kalantry S., Magnuson T., et al. Differences between homologous alleles of olfactory receptor genes require the Polycomb Group protein Eed. J Cell Biol 2007, 179:269-276.
19. Mosser D.M., Edwards J.P. Exploring the full spectrum of macrophage activation. Nat Rev Immunol 2008, 8:958-969.
20. Billack B. Macrophage activation: role of toll-like receptors, nitric oxide, and nuclear factor kappa B. Am J Pharm Educ 2006, 70:102.
21. Ma J., Chen T., Mandelin J., Ceponis A., Miller N.E., Hukkanen M., et al. Regulation of macrophage activation. Cell Mol Life Sci 2003, 60:2334-2346.
22. Diggle S.P., Winzer K., Chhabra S.R., Worrall K.E., Camara M., Williams P. The Pseudomonas aeruginosa quinolone signal molecule overcomes the cell density-dependency of the quorum sensing hierarchy, regulates rhl-dependent genes at the onset of stationary phase and can be produced in the absence of LasR. Mol Microbiol 2003, 50:29-43.
23. Diggle S.P., Lumjiaktase P., Dipilato F., Winzer K., Kunakorn M., Barrett D.A., et al. Functional genetic analysis reveals a 2-alkyl-4-quinolone signaling system in the human pathogen Burkholderia pseudomallei and related bacteria. Chem Biol 2006, 13:701-710.
24. Hwang S.S., Kim Y.U., Lee W., Lee G.R. Differential expression of nuclear receptors in T helper cells. J Microbiol Biotechnol 2009, 19:208-214.