Synthesis of carbon-11-labeled tricyclic necroptosis inhibitors as new potential PET agents for imaging of tumor necrosis factor α (TNF-α)

Applied Radiation and Isotopes

Volumn 68, Issue 10, 2010, Pages 1950-1958

  Gao, Mingzhang ^a   Lola, Christian M ^a   Wang, Min ^a   Miller, Kathy D ^a   Sledge, George W ^a   Hutchins, Gary D ^a   Zheng, Qi Huang ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Imaging; Positron emission tomography; Radiotracers; Tricyclic necroptosis inhibitors; Tumor necrosis factor

Indexed keywords

BASIC CONDITIONS; CARBON-11; RADIOCHEMICAL PURITY; RADIOCHEMICAL YIELD; SPECIFIC ACTIVITY; SYNTHESIS TIME; TUMOR NECROSIS FACTORS;

GLYCOPROTEINS; MACROPHAGES; POSITRONS; RADIOACTIVE TRACERS; TUMORS;

POSITRON EMISSION TOMOGRAPHY;

3,3A,4,5 TETRAHYDRO 2H BENZ[G]INDAZOLE DERIVATIVE; CARBON 11; RADIOPHARMACEUTICAL AGENT; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG DESIGN; DRUG ISOLATION; DRUG PURITY; DRUG SPECIFICITY; DRUG STRUCTURE; DRUG SYNTHESIS; ISOTOPE LABELING; ISOTOPE TRACING; MOLECULAR IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIOCHEMISTRY; RADIOISOTOPE DECAY; SOLID PHASE EXTRACTION;

CARBON RADIOISOTOPES; HUMANS; ISOTOPE LABELING; NECROSIS; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77955266457     PISSN: 09698043     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.apradiso.2010.04.030     Document Type: Article

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