The relative health benefits of different sexual activities

Journal of Sexual Medicine

Volumn 7, Issue 4 PART 1, 2010, Pages 1336-1361

  Brody, Stuart ^a  

^a UNIVERSITY OF THE WEST OF SCOTLAND   (United Kingdom)

Author keywords

Health Behaviors; Masturbation; Sexual Intercourse

Indexed keywords

ANTIBIOTIC AGENT; ASCORBIC ACID;

ALEXITHYMIA; ANUS INTERCOURSE; BREAST CANCER; CARDIOVASCULAR FUNCTION; CLINICAL TRIAL; CONDOM; CONSULTATION; DEFENSE MECHANISM; DEPRESSION; DRUG MEGADOSE; ERECTILE DYSFUNCTION; EVIDENCE BASED PRACTICE; HORMONAL REGULATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LIFE EXPECTANCY; MASTURBATION; MENTAL DISEASE; MENTAL HEALTH; MOOD DISORDER; MUSCULOSKELETAL DISEASE; PEER REVIEW; PELVIS PAIN SYNDROME; PHYSICAL ACTIVITY; PREECLAMPSIA; PRIORITY JOURNAL; PROSTATE CANCER; PSYCHOLOGICAL ASPECT; PSYCHOTHERAPY; REVIEW; RISK ASSESSMENT; SEXUAL BEHAVIOR; SEXUAL EDUCATION; SEXUAL HEALTH; SEXUAL INTERCOURSE; SEXUAL SATISFACTION;

EID: 77955263582     PISSN: 17436095     EISSN: 17436109     Source Type: Journal    
DOI: 10.1111/j.1743-6109.2009.01677.x     Document Type: Review

References (174)

1. Brody S. Penile-vaginal intercourse is better: Evidence trumps ideology. Sex Relat Ther 2006, 21:393-403.
2. Levin RJ. Sexual activity, health and well-being-The beneficial roles of coitus and masturbation. Sex Relat Ther 2007, 22:135-48.
3. Whipple B, Koch PB, Moglia RF, Owens AF, Samuels H. The Health Benefits of Sexual Expression. 2007, http://www.hawaii.edu/hivandaids/Health%20Benefits%20of%20Sexual%20Expression.pdf, Planned Parenthood Federation of America, Available at: (accessed November 30, 2009
4. Henning K, Jones AR, Holdford R. I didn't do it, but if I did I had a good reason": Minimization, denial, and attributions of blame among male and female domestic violence offenders. J Fam Violence 2005, 20:131-9.
5. Wiechman SA, Smith RE, Smoll FL, Ptacek JT. Masking effects of social desirability response set on relations between psychosocial factors and sport injuries: A methodological note. J Sci Med Sport 2000, 3:194-202.
6. Novotny JA, Rumpler WV, Riddick H, Hebert JR, Rhodes D, Judd JT, Baer DJ, McDowell M, Briefel R. Personality characteristics as predictors of underreporting of energy intake on 24-hour dietary recall interviews. J Am Diet Assoc 2003, 103:1146-51.
7. Scagliusi FB, Ferriolli E, Pfrimer K, Laureano C, Cunha CS, Gualano B, Lourenco BH, Lancha AH. Characteristics of women who frequently under report their energy intake: A doubly labelled water study. Eur J Clin Nutr 2009, 63:1192-9.
8. Taren DL, Tobar M, Hill A, Howell W, Shisslak C, Bell I, Ritenbaugh C. The association of energy intake bias with psychological scores of women. Eur J Clin Nutr 1999, 53:570-8.
9. Brody S, Veit R, Rau H. Lie scores are associated with less cardiovascular reactivity to baroreceptor stimulation and to mental arithmetic stress. Pers Individ Dif 1997, 22:677-81.
10. Brody S, Wagner D, Heinrichs M, James A, Hellhammer D, Ehlert U. Social desirability scores are associated with higher morning cortisol levels in firefighters. J Psychosom Res 2000, 49:227-8.
11. Brody S, Costa RM. Satisfaction (sexual, life, relationship, and mental health) is associated directly with penile-vaginal intercourse but inversely with other sexual behavior frequencies. J Sex Med 2009, 6:1947-54.
12. Brody S. Vaginal orgasm is associated with better psychological function. Sex Relat Ther 2007, 22:173-91.
13. Lewin B, Fugl-Meyer K, Helmius G, Lalos A, Mansson S-A. Sex in Sweden: On the Swedish sexual life 2000, The National Institute of Public Health (Sweden)
14. Langstrom N, Hanson RK. High rates of sexual behavior in the general population: Correlates and predictors. Arch Sex Behav 2006, 35:37-52.
15. Costa RM, Brody S. Women's relationship quality is associated with specifically penile-vaginal intercourse orgasm and frequency. J Sex Marital Ther 2007, 33:319-27.
16. Hurlbert DF, Apt C. Female sexual desire, response, and behavior. Behav Modif 1994, 18:488-504.
17. Gebhard PH. Factors in marital orgasm. J Soc Issues 1966, 22:88-95.
18. Parker JD, Taylor GJ, Bagby RM. Alexithymia: Relationship with ego defense and coping styles. Compr Psychiatry 1998, 39:91-8.
19. Madioni F, Mammana LA. Toronto alexithymia scale in outpatients with sexual disorders. Psychopathology 2001, 34:95-8.
20. Wise TN, Osborne C, Strand J, Fagan PJ, Schmidt CW. Alexithymia in patients attending a sexual disorders clinic. J Sex Marital Ther 2002, 28:445-50.
21. Brody S. Alexithymia is inversely associated with women's frequency of vaginal intercourse. Arch Sex Behav 2003, 32:73-7.
22. Brody S, Laan E, Van Lunsen RHW. Concordance between women's physiological and subjective sexual arousal is associated with consistency of orgasm during intercourse but not other sexual behavior. J Sex Marital Ther 2003, 29:15-23.
23. Brody S. Intercourse orgasm consistency, concordance of women's genital and subjective sexual arousal, and erotic stimulus presentation sequence. J Sex Marital Ther 2007, 33:31-9.
24. Brody S, Costa RM. Vaginal orgasm is associated with less use of immature psychological defense mechanisms. J Sex Med 2008, 5:1167-76.
25. Costa RM, Brody S. Condom use for penile-vaginal intercourse is associated with immature psychological defense mechanisms. J Sex Med 2008, 5:2522-32.
26. Bond M. Empirical studies of defense style: Relationships with psychopathology and change. Harv Rev Psychiatry 2004, 12:263-78.
27. Perry JC, Cooper SH. An empirical study of defense mechanisms. I. Clinical interview and life vignette ratings. Arch Gen Psychiatry 1989, 46:444-52.
28. Diagnostic and statistical manual of mental disorders 2000, American Psychiatric Association, 4th, edition. Text Revision ed, Washington, DC, American Psychiatric Association
29. Cramer P. Personality, personality disorders, and defense mechanisms. J Pers 1999, 67:535-54.
30. Andrews G, Singh M, Bond M. The defense style questionnaire. J Nerv Ment Dis 1993, 181:246-56.
31. Costa RM, Brody S. Immature defense mechanisms are associated with lesser vaginal orgasm consistency and greater alcohol consumption before sex. J Sex Med 2009, Nov 3 [Epub ahead of print] doi: 10.1111/j.1743-6109.2009.01559.x
32. Crosby R, Milhausen R, Yarber WL, Sanders SA, Graham CA. Condom "turn offs" among adults: An exploratory study. Int J STD AIDS 2008, 19:590-4.
33. Morrill AC, Ickovics JR, Golubchikov VV, Beren SE, Rodin J. Safer sex: Social and psychological predictors of behavioral maintenance and change among heterosexual women. J Consult Clin Psychol 1996, 64:819-28.
34. Husted J, Edwards A. Personality correlates of male sexual arousal and behavior. Arch Sex Behav 1976, 5:149-56.
35. Frohlich P, Meston C. Sexual functioning and self-reported depressive symptoms among college women. J Sex Res 2002, 39:321-5.
36. Cyranowski JM, Bromberger J, Youk A, Matthews K, Kravitz HM, Powell LH. Lifetime depression history and sexual function in women at midlife. Arch Sex Behav 2004, 33:539-48.
37. Das A. Masturbation in the United States. J Sex Marital Ther 2007, 33:301-17.
38. Gallup GG, Burch RL, Platek SM. Does semen have antidepressant properties? Arch Sex Behav. 2002, 31:289-93.
39. Burch RL, Gallup GGJ. The psychobiology of human semen. Female infidelity and paternal uncertainty: Evolutionary perspectives on male anti-cuckoldry tactics 2006, 141-72. Platek SM, Shackelford TK. In, eds., New York, Cambridge University Press
40. Gerressu M, Mercer CH, Graham CA, Wellings K, Johnson AM. Prevalence of masturbation and associated factors in a British national probability survey. Arch Sex Behav 2008, 37:266-78.
41. Sandfort TG, de Graaf R, Bijl RV, Schnabel P. Same-sex sexual behavior and psychiatric disorders: Findings from the Netherlands Mental Health Survey and Incidence Study (NEMESIS). Arch Gen Psychiatry 2001, 58:85-91.
42. Sandfort TG, Bakker F, Schellevis FG, Vanwesenbeeck I. Sexual orientation and mental and physical health status: Findings from a Dutch population survey. Am J Public Health 2006, 96:1119-25.
43. de Graaf R, Sandfort TG, ten Have M. Suicidality and sexual orientation: Differences between men and women in a general population-based sample from the Netherlands. Arch Sex Behav 2006, 35:253-62.
44. Blaya C, Dornelles M, Blaya R, Kipper L, Heldt E, Isolan L, Bond M, Manfro GG. Do defense mechanisms vary according to the psychiatric disorder? Rev Bras Psiquiatr 2006, 28:179-83.
45. Multiple chances: Findings from the United Kingdom gay men's sex survey 2006. 2008, http://www.sigmaresearch.co.uk/files/report2008c.pdf, Sigma Research, Available at: (accessed November 30, 2009
46. Testing targets: Findings from the United Kingdom gay men's sex survey 2007. 2009, http://www.sigmaresearch.co.uk/files/report2009f.pdf, Sigma Research, Available at: (accessed November 30, 2009
47. Zietsch BP, Verweij KJH, Bailey JM, Wright MJ, Martin NG. Sexual orientation and vulnerability psychiatric: A twin study of neuroticism and psychoticism. Arch Sex Behav 2009, Jul 9 [Epub ahead of print] doi: 10.1007/s10508-009-9508-4
48. Macdonald S, Halliday J, MacEwan T, Sharkey V, Farrington S, Wall S, McCreadie RG. Nithsdale Schizophrenia Surveys 24: Sexual dysfunction: Case-control study. Br J Psychiatry 2003, 182:50-6.
49. Clayton AH, Balon R. The impact of mental illness and psychotropic medications on sexual functioning: The Evidence and Management. J Sex Med 2009, 6:1200-11.
50. Raboch J. Sexual development and life of psychiatric female patients. Arch Sex Behav 1986, 15:341-53.
51. Kratochvil S. Sexualni stimulace a zensky orgasmus [Sexual stimulation and female orgasm. Ceska a Slovenska Psychiatrie 1993, 89:191-9.
52. Nedoma K, Sipova I. Sexual behavior and reactivity in prostitutes. Ceskoslovenska Psychiatr 1972, 68:214-7.
53. Brody S, Potterat JJ, Muth SQ, Woodhouse DE. Psychiatric and characterological factors relevant to excess mortality in a long-term cohort of prostitute women. J Sex Marital Ther 2005, 31:97-112.
54. Potterat JJ, Brewer DD, Muth SQ, Rothenberg RB, Woodhouse DE, Muth JB, Stites HK, Brody S. Mortality in a long-term open cohort of prostitute women. Am J Epidemiol 2004, 159:778-85.
55. Althof SE, Turner LA, Levine SB, Risen C, Kursh ED, Bodner D, Resnick M. Intracavernosal injection in the treatment of impotence: A prospective study of sexual, psychological, and marital functioning. J Sex Marital Ther 1987, 13:155-67.
56. Drabick JJ, Gambel JM, Mackey JF. Prostatodynia in United Nations peacekeeping forces in Haiti. Mil Med 1997, 162:380-3.
57. Whipple B, Komisaruk BR. Analgesia produced in women by genital self-stimulation. J Sex Res 1988, 24:130-40.
58. Komisaruk BR, Whipple B. The suppression of pain by genital stimulation in females. Ann Rev Sex Res 1995, 6:151-86.
59. Crowley WR, Rodriguez-Sierra JF, Komisaruk BR. Analgesia induced by vaginal stimulation in rats is apparently independent of a morphine-sensitive process. Psychopharmacology 1977, 54:223-5.
60. Levin RJ. Do women gain anything from coitus apart from pregnancy? Changes in the human female genital tract activated by coitus. J Sex Marital Ther 2003, 29:59-69.
61. Nicholas A, Brody S, de Sutter P, de Carufel F. A woman's history of vaginal orgasm is discernible from her walk. J Sex Med 2008, 5:2119-24.
62. Brody S. Slimness is associated with greater intercourse and lesser masturbation frequency. J Sex Marital Ther 2004, 30:251-61.
63. Edmonds ES, Withyachumnarnkul B. Sexual behavior of the obese male Zucker rat. Physiol Behav 1980, 24:1139-41.
64. Wetsman A, Marlowe F. How universal are preferences for female waist-to-hip ratios? Evidence from the Hadza of Tanzania. Evol Hum Behav 1999, 20:219-28.
65. Williamson DF, Thompson TJ, Anda RF, Dietz WH, Felitti V. Body weight and obesity in adults and self-reported abuse in childhood. Int J Obes Relat Metab Disord 2002, 26:1075-82.
66. Goldbacher EM, Matthews KA. Are psychological characteristics related to risk of the metabolic syndrome? A review of the literature. Ann Behav Med 2007, 34:240-52.
67. Brody S, Preut R. Cannabis, tobacco, and caffeine use modify the blood pressure reactivity protection of ascorbic acid. Pharmacol Biochem Behav 2002, 72:811-6.
68. Brody S, Preut R, Schommer K, Schurmeyer TH. A randomized controlled trial of high dose ascorbic acid for reduction of blood pressure, cortisol, and subjective responses to psychological stress. Psychopharmacology 2002, 159:319-24.
69. Brody S. High-dose ascorbic acid increases intercourse frequency and improves mood: A randomized controlled clinical trial. Biol Psychiatry 2002, 52:371-4.
70. Brody S, Preut R. Vaginal intercourse frequency and heart rate variability. J Sex Marital Ther 2003, 29:371-80.
71. Brody S, Veit R, Rau H. A preliminary report relating frequency of vaginal intercourse to heart rate variability, Valsalva ratio, blood pressure, and cohabitation status. Biol Psychol 2000, 52:251-7.
72. Fogari R, Zoppi A, Preti P, Rinaldi A, Marasi G, Vanasia A, Mugellini A. Sexual activity and plasma testosterone levels in hypertensive males. Am J Hypertens 2002, 15:217-21.
73. Brody S. Blood pressure reactivity to stress is better for people who recently had penile-vaginal intercourse than for people who had other or no sexual activity. Biol Psychol 2006, 71:214-22.
74. Bohlen JG, Held JP, Sanderson MO, Patterson RP. Heart rate, rate-pressure product, and oxygen uptake during four sexual activities. Arch Int Med 1984, 144:1745-8.
75. Klonoff-Cohen HS, Savitz DA, Cefalo RC, McCann MF. An epidemiologic study of contraception and preeclampsia. JAMA 1989, 262:3143-7.
76. Einarsson JI, Sangi-Haghpeykar H, Gardner MO. Sperm exposure and development of preeclampsia. Am J Obstet Gynecol 2003, 188:1241-3.
77. Koelman CA, Coumans AB, Nijman HW, Doxiadis II, Dekker GA, Claas FH. Correlation between oral sex and a low incidence of preeclampsia: A role for soluble HLA in seminal fluid? J Reprod Immunol 2000, 46:155-66.
78. Jannini EA, Screponi E, Carosa E, Pepe M, Lo Giudice F, Trimarchi F, Benvenga S. Lack of sexual activity from erectile dysfunction is associated with a reversible reduction in serum testosterone. Int J Androl 1999, 22:385-92.
79. Carosa E, Benvenga S, Trimarchi F, Lenzi A, Pepe M, Simonelli C, Jannini EA. Sexual inactivity results in reversible reduction of LH bioavailability. Int J Impot Res 2002, 14:93-9.
80. Saraiva KL, Silva AK, Wanderley MI, De Araujo AA, De Souza JR, Peixoto CA. Chronic treatment with sildenafil stimulates Leydig cell and testosterone secretion. Int J Exp Pathol 2009, 90:454-62.
81. Akinwale SO. Comparative study of coitus and non-coitus in the treatment of menopausal symptoms. Afr J Med Med Sci 2007, 36:17-21.
82. Brody S. Age at first intercourse is inversely related to female cortisol stress reactivity. Psychoneuroendocrinology 2002, 27:933-43.
83. Kohlert JG, Rowe RK, Meisel RL. Intromissive stimulation from the male increases extracellular dopamine release from fluoro-gold-identified neurons within the midbrain of female hamsters. Horm Behav 1997, 32:143-54.
84. Kruger TH, Haake P, Hartmann U, Schedlowski M, Exton MS. Orgasm-induced prolactin secretion: Feedback control of sexual drive? Neurosci Biobehav Rev 2002, 26:31-44.
85. Kruger TH, Hartmann U, Schedlowski M. Prolactinergic and dopaminergic mechanisms underlying sexual arousal and orgasm in humans. World J Urol 2005, 23:130-8.
86. Brody S, Kruger THC. The post-orgasmic prolactin increase following intercourse is greater than following masturbation and suggests greater satiety. Biol Psychol 2006, 71:312-5.
87. Philippsohn S, Hartmann U. Determinants of sexual satisfaction in a sample of German women. J Sex Med 2009, 6:1001-10.
88. Corona G, Ricca V, Boddi V, Bandini E, Lotti F, Fisher AD, Sforza A, Forti G, Mannucci E, Maggi M. Autoeroticism, mental health, and organic disturbances in patients with erectile dysfunction. J Sex Med 2010, 7:182-91.
89. Sofikitis NV, Miyagawa I. Endocrinological, biophysical, and biochemical parameters of semen collected via masturbation versus sexual intercourse. J Androl 1993, 14:366-73.
90. Purvis K, Magnus O, Morkas L, Abyholm T, Rui H. Ejaculate composition after masturbation and coitus in the human male. Int J Androl 1986, 9:401-6.
91. Zavos PM, Goodpasture JC. Clinical improvements of specific seminal deficiencies via intercourse with a seminal collection device versus masturbation. Fertil Steril 1989, 51:190-3.
92. Giles GG, Severi G, English DR, McCredie MR, Borland R, Boyle P, Hopper JL. Sexual factors and prostate cancer. BJU Int 2003, 92:211-6.
93. Leitzmann MF, Platz EA, Stampfer MJ, Willett WC, Giovannucci E. Ejaculation frequency and subsequent risk of prostate cancer. JAMA 2004, 291:1578-86.
94. Brody S. Sexual factors and prostate cancer. BJU Int 2004, 93:180.
95. Dimitropoulou P, Lophatananon A, Easton D, Pocock R, Dearnaley DP, Guy M, Edwards S, O'Brien L, Hall A, Wilkinson R, Eeles R, Muir KR. Sexual activity and prostate cancer risk in men diagnosed at a younger age. BJU Int 2009, 103:178-85.
96. Bosland MC. The etiopathogenesis of prostatic cancer with special reference to environmental factors. Adv Cancer Res 1988, 51:1-106.
97. Mandel JS, Schuman LM. Sexual factors and prostatic cancer: Results from a case-control study. J Gerontol 1987, 42:259-64.
98. Le MG, Bachelot A, Hill C. Characteristics of reproductive life and risk of breast cancer in a case-control study of young nulliparous women. J Clin Epidemiol 1989, 42:1227-33.
99. Gjorgov AN. Barrier contraceptive practice and male infertility as related factors to breast cancer in married women. Oncology 1978, 35:97-100.
100. Gjorgov AN. Breast cancer and barrier contraception: Postulated and corroborated potential for prevention. Folia Med 1998, 40:17-23.
101. Rossing MA, Stanford JL, Weiss NS, Daling JR. Indices of exposure to fetal and sperm antigens in relation to the occurrence of breast cancer. Epidemiology 1996, 7:309-11.
102. Fraumeni JF, Lloyd JW, Smith EM, Wagoner JK. Cancer mortality among nuns: Role of marital status in etiology of neoplastic disease in women. J Natl Cancer Inst 1969, 42:455-68.
103. St Lawrence JS, Klaskala W, Kankasa C, West JT, Mitchell CD, Wood C. Factors associated with HIV prevalence in a pre-partum cohort of Zambian women. Int J STD AIDS 2006, 17:607-13.
104. Potterat JJ, Muth SQ, Brody S. Evidence undermining the adequacy of the HIV reproduction number formula. Sex Transm Dis 2000, 27:644-5.
105. Potterat JJ, Brody S. Does sex explain HIV transmission dynamics in developing countries? Sex Transm Dis 2001, 28:730.
106. Potterat JJ, Brody S. HIV epidemicity in context of STI declines: A telling discordance. Sex Transm Infect 2002, 78:467.
107. Potterat JJ. HIV infection in rural Florida. N Engl J Med 1993, 328:1351. author reply 2
108. Gisselquist D, Potterat JJ, Brody S, Vachon F. Let it be sexual: How health care transmission of AIDS in Africa was ignored. Int J STD AIDS 2003, 14:148-61.
109. Gisselquist D, Potterat JJ, Brody S. Running on empty: Sexual co-factors are insufficient to fuel Africa's turbocharged HIV epidemic. Int J STD AIDS 2004, 15:442-52.
110. Gisselquist D, Potterat JJ, Brody S. HIV transmission during paediatric health care in sub-Saharan Africa-Risks and evidence. S Afr Med J 2004, 94:109-16.
111. Gisselquist D, Potterat JJ. Confound it: Latent lessons from the Mwanza trial of STD treatment to reduce HIV transmission. Int J STD AIDS 2003, 14:179-84.
112. Gisselquist D, Friedman E, Potterat JJ, Minkin SF, Brody S. Four policies to reduce HIV transmission through unsterile health care. Int J STD AIDS 2003, 14:717-22.
113. Gisselquist D. Points to consider: Responses to HIV/AIDS in Africa, Asia, and the Caribbean 2008, http://davidgisselquist.googlepages.com/pointstoconsider, London, Adonis & Abbey Publishers, Available at: (accessed November 30, 2009
114. Deuchert E, Brody S. The role of health care in the spread of HIV/AIDS in Africa: Evidence from Kenya. Int J STD AIDS 2006, 17:749-52.
115. Deuchert E, Brody S. Lack of autodisable syringe use and health care indicators are associated with high HIV prevalence: An international ecologic analysis. Ann Epidemiol 2007, 17:199-207.
116. Deuchert E, Brody S. The evidence for health-care transmission of HIV in Africa should determine prevention priorities. Int J STD AIDS 2007, 18:290-1.
117. Brody S, Potterat JJ. Assessing the role of anal intercourse in the epidemiology of AIDS in Africa. Int J STD AIDS 2003, 14:431-6.
118. Brody S, Potterat JJ. Establishing valid AIDS monitoring and research in countries with generalized epidemics. Int J STD AIDS 2004, 15:1-6.
119. Brody S. Heterosexual transmission of HIV. N Engl J Med 1994, 331:1718.
120. Brody S. Patients misrepresenting their risk factors for AIDS. Int J STD AIDS 1995, 6:392-8.
121. Brody S. Lack of evidence for transmission of human-immunodeficiency-virus through vaginal intercourse. Arch Sex Behav 1995, 24:383-93.
122. Brody S. Continued lack of evidence for transmission of human immunodeficiency virus through vaginal intercourse: A reply to Carey and Kalichman. Arch Sex Behav 1996, 25:329-37.
123. Brody S. The unhealthy attempts by CDC and WHO to deny the importance of HIV transmission through unsafe health care. Int J STD AIDS 2009, 20:70-2.
124. Brewer DD, Potterat JJ, Roberts JM, Brody S. Male and female circumcision associated with prevalent HIV infection in virgins and adolescents in Kenya, Lesotho, and Tanzania. Ann Epidemiol 2007, 17:217-26.
125. Brewer DD, Potterat JJ, Roberts JM, Brody S. Circumcision-related HIV risk and the unknown mechanism of effect in the male circumcision trials. Ann Epidemiol 2007, 17:928-9.
126. Brewer DD, Potterat JJ, Gisselquist D, Dinsmore WW, St Lawrence JS, Brody S. Valid evaluation of iatrogenic and sexual HIV transmission requires proof. AIDS 2007, 21:2556-7.
127. Brewer DD, Potterat JJ, Brody S. Male circumcision in HIV prevention. Lancet 2007, 369:1597.
128. Brody S. Declining HIV rates in Uganda: Due to cleaner needles, not abstinence or condoms. Int J STD AIDS 2004, 15:440-1.
129. Peters EJ, Brewer DD, Udonwa NE, Jombo GTA, Essien OE, Umoh VA, Otu AA, Eduwem DU, Potterat JJ. Diverse blood exposures associated with incident HIV infection in Calabar, Nigeria. Int J STD AIDS 2009, 20:846-51.
130. Deuchert E, Brody S. Plausible and implausible parameters for mathematical modeling of nominal heterosexual HIV transmission. Ann Epidemiol 2007, 17:237-44.
131. McQuillan GM, Kruszon-Moran D, Granade T, Feldman JW. Seroprevalence of human immunodeficiency virus in the US household population aged 18-49 years: The National Health and Nutrition Examination Surveys, 1999-2006. J Acquir Immune Defic Syndr 2010, 53:117-23.
132. Dezzutti CS, Guenthner PC, Cummins JE, Cabrera T, Marshall JH, Dillberger A, Lal RB. Cervical and prostate primary epithelial cells are not productively infected but sequester human immunodeficiency virus type 1. J Infect Dis 2001, 183:1204-13.
133. Greenhead P, Hayes P, Watts PS, Laing KG, Griffin GE, Shattock RJ. Parameters of human immunodeficiency virus infection of human cervical tissue and inhibition by vaginal virucides. J Virol 2000, 74:5577-86.
134. Bouschbacher M, Bomsel M, Verronese E, Gofflo S, Ganor Y, Dezutter-Dambuyant C, Valladeau J. Early events in HIV transmission through a human reconstructed vaginal mucosa. AIDS 2008, 22:1257-66.
135. Ratnam KV. Effect of sexual practices on T cell subsets and delayed hypersensitivity in transsexuals and female sex workers. Int J STD AIDS 1994, 5:257-61.
136. Richards JM, Bedford JM, Witkin SS. Rectal insemination modifies immune responses in rabbits. Science 1984, 224:390-2.
137. Peters B, Whittall T, Babaahmady K, Gray K, Vaughan R, Lehner T. Effect of heterosexual intercourse on mucosal alloimmunisation and resistance to HIV-1 infection. Lancet 2004, 363:518-24.
138. Palmore EB. Predictors of the longevity difference: A 25-year follow-up. Gerontologist 1982, 22:513-8.
139. Davey Smith G, Frankel S, Yarnell J. Sex and death: Are they related? Findings from the Caerphilly cohort study. Br Med J 1997, 315:1641-4.
140. Brody S. Sex at risk: Lifetime number of partners, frequency of intercourse, and the low AIDS risk of vaginal intercourse 1997, New Brunswick, NJ, Transaction Publishers
141. Wysowski DK, Farinas E, Swartz L. Comparison of reported and expected deaths in sildenafil (Viagra) users. Am J Cardiol 2002, 89:1331-4.
142. Giri S, Thompson PD, Kiernan FJ, Clive J, Fram DB, Mitchel JF, Hirst JA, McKay RG, Waters DD. Clinical and angiographic characteristics of exertion-related acute myocardial infarction. JAMA 1999, 282:1731-6.
143. Wagner WE, Kelley RJ, Tucker KR, Harper CJ. Females receive a life-span benefit from male ejaculates in a field cricket. Evolution 2001, 55:994-1001.
144. Knoll J, Yen TT, Miklya I. Sexually low performing male rats die earlier than their high performing peers and (-)deprenyl treatment eliminates this difference. Life Sci 1994, 54:1047-57.
145. Miller GF. Are polygenic mutations and Holocene selective sweeps the only evolutionary-genetic processes left for explaining heritable variation in human psychological traits? The evolution of personality and individual differences Buss DMHawley PH. In, eds., New York, Oxford University Press, in press
146. Slimp JC, Hart BL, Goy RW. Heterosexual, autosexual and social behavior of adult male rhesus monkeys with medial preoptic-anterior hypothalamic lesions. Brain Res 1978, 142:105-22.
147. Komisaruk BR, Whipple B. Love as sensory stimulation: Physiological consequences of its deprivation and expression. Psychoneuroendocrinology 1998, 23:927-44.
148. Komisaruk BR, Whipple B. Functional MRI of the brain during orgasm in women. Annu Rev Sex Res 2005, 16:62-86.
149. Gellhorn E. Principles of autonomic-somatic integrations 1967, Minneapolis, University of Minnesota Press
150. Pfaus JG, Manitt C, Coopersmith CB. Effects of pelvic, pudendal, or hypogastric nerve cuts on Fos induction in the rat brain following vaginocervical stimulation. Physiol Behav 2006, 89:627-36.
151. Shafik A. Vaginocavernosus reflex. Clinical significance and role in sexual act. Gynecol Obstet Invest 1993, 35:114-7.
152. Shafik A. Cervico-motor reflex: Description of the reflex and role in sexual acts. J Sex Res 1996, 33:153-7.
153. Dawkins R. The selfish gene 1989, New York, Oxford University Press
154. Johnston RE, Zahorik DM, Immler K, Zakon H. Alterations of male sexual behavior by learned aversions to hamster vaginal secretion. J Comp Physiol Psychol 1978, 92:85-93.
155. Dawood K, Kirk KM, Bailey JM, Andrews PW, Martin NG. Genetic and environmental influences on the frequency of orgasm in women. Twin Res Hum Genet 2005, 8:27-33.
156. Dunn KM, Cherkas LF, Spector TD. Genetic influences on variation in female orgasmic function: A twin study. Biol Lett 2005, 1:260-3.
157. Harris JM, Cherkas LF, Kato BS, Heiman JR, Spector TD. Normal variations in personality are associated with coital orgasmic infrequency in heterosexual women: A population-based study. J Sex Med 2008, 5:1177-83.
158. Hayashi M, Miyake Y, Minakawa K. Reliability and validity of the Japanese edition of the Defense Style Questionnaire 40. Psychiatry Clin Neurosci 2004, 58:152-6.
159. Harden KP, Mendle J, Hill JE, Turkheimer E, Emery RE. Rethinking timing of first sex and delinquency. J Youth Adolesc 2008, 37:373-85.
160. Rosen R, Brown C, Heiman J, Leiblum S, Meston C, Shabsigh R, Ferguson D, D'Agostino R. The Female Sexual Function Index (FSFI): A multidimensional self-report instrument for the assessment of female sexual function. J Sex Marital Ther 2000, 26:191-208.
161. Rosen RC, Riley A, Wagner G, Osterloh IH, Kirkpatrick J, Mishra A. The international index of erectile function (IIEF): A multidimensional scale for assessment of erectile dysfunction. Urology 1997, 49:822-30.
162. Brody S, Weiss P. Vaginal orgasm is associated with vaginal (not clitoral) sex education, focusing mental attention on vaginal sensations, intercourse duration, and a preference for a longer penis. J Sex Med 2009, Sep 1 [Epub ahead of print] doi: 10.1111/j.1743-6109.2009.01469.x
163. de Carufel F, Trudel G. Effects of a new functional-sexological treatment for premature ejaculation. J Sex Marital Ther 2006, 32:97-114.
164. Pierce AP. The coital alignment technique (CAT): An overview of studies. J Sex Marital Ther 2000, 26:257-68.
165. Kegel AH. The Kinsey report. JAMA 1953, 153:1303-4.
166. Perry JD. The primitive psychology of Alfred Kinsey. 1984, http://www.doctorg.com/primitive-psychology-kinsey.htm, Presented as a paper at the Spring Scientific Meeting of the Maine Psychological Association, Lewiston, Available at: (accessed November 30, 2009
167. Weiss P, Brody S. Female sexual arousal disorder with and without a distress criterion: Prevalence and correlates in a representative Czech sample. J Sex Med 2009, 6:3385-94.
168. Weiss P, Brody S. Women's partnered orgasm consistency is associated with greater duration of penile-vaginal intercourse but not of foreplay. J Sex Med 2009, 6:135-41.
169. Foster R, Mears A, Goldmeier D. A literature review and case reports series on the use of phosphodiesterase inhibitors in the treatment of female sexual dysfunction. Int J STD AIDS 2009, 20:152-7.
170. Brody S. Phosphodiesterase inhibitors and vaginal intercourse orgasm. Int J STD AIDS 2009, 20:440.
171. Esposito K, Ciotola M, Maiorino MI, Giugliano F, Autorino R, De Sio M, Cozzolino D, Saccomanno F, Giugliano D. Hyperlipidemia and sexual function in premenopausal women. J Sex Med 2009, 6:1696-703.
172. Muller MM, Rau H, Brody S, Elbert T, Heinle H. The relationship between habitual anger coping style and serum-lipid and lipoprotein concentrations. Biol Psychol 1995, 41:69-81.
173. Waldstein SR, Polefrone JM, Bachen EA, Muldoon MF, Kaplan JR, Manuck SB. Relationship of cardiovascular reactivity and anger expression to serum lipid concentrations in healthy young men. J Psychosom Res 1993, 37:249-56.
174. Goldstein I. The mutually reinforcing triad of depressive symptoms, cardiovascular disease, and erectile dysfunction. Am J Cardiol 2000, 86:41F-5.