메뉴 건너뛰기




Volumn 22, Issue 8, 2010, Pages 952-960

Detection of hepatitis B virus covalently closed circular DNA in paraffin-embedded and cryo-preserved liver biopsies of chronic hepatitis B patients

Author keywords

cccDNA; cryo preserved liver biopsies; hepatitis B; paraffin embedded liver biopsies

Indexed keywords

CIRCULAR DNA; COVALENTLY CLOSED CIRCULAR DNA; EDETIC ACID; FORMALDEHYDE; PARAFFIN; UNCLASSIFIED DRUG; VIRUS DNA; HEPATITIS B(E) ANTIGEN;

EID: 77955207859     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/MEG.0b013e3283376a63     Document Type: Article
Times cited : (15)

References (31)
  • 1
    • 42249105661 scopus 로고    scopus 로고
    • Hepatitis B
    • World Health Organization. Revised August 2008 World Health Organization
    • World Health Organization. Hepatitis B. World Health Organization Fact Sheet 204 (Revised August 2008). World Health Organization, 2007.
    • (2007) World Health Organization Fact Sheet , pp. 204
  • 4
    • 0001435504 scopus 로고    scopus 로고
    • Hapdnaviridae: The viruses and their replication
    • Knipe DM, Howley PM, editors 4th edn. Philadelphia: Wolters Kluwer Chapter 29
    • Ganem D, Schneider RJ. Hapdnaviridae: the viruses and their replication. In: Knipe DM, Howley PM, editors. Fields virology. 4th edn. Philadelphia: Wolters Kluwer; 2002. pp. 2923-2968. Chapter 29.
    • (2002) Fields Virology , pp. 2923-2968
    • Ganem, D.1    Schneider, R.J.2
  • 5
    • 0023028191 scopus 로고
    • Formation of the pool of covalently closed circular viral DNA in hepadnavirus-infected cells
    • Tuttleman JS, Pourcel C, Summers J. Formation of the pool of covalently closed circular viral DNA in hepadnavirus-infected cells. Cell 1986; 47:451-460.
    • (1986) Cell , vol.47 , pp. 451-460
    • Tuttleman, J.S.1    Pourcel, C.2    Summers, J.3
  • 6
    • 0029037074 scopus 로고
    • The covalently closed duplex form of the hepadnavirus genome exists in situ as a heterogeneous population of viral minichromosomes
    • Newbold JE, Xin H, Tencza M, Sherman G, Dean J, Bowden S, Locarnini S. The covalently closed duplex form of the hepadnavirus genome exists in situ as a heterogeneous population of viral minichromosomes. J Virol 1995; 69:3350-3357.
    • (1995) J Virol , vol.69 , pp. 3350-3357
    • Newbold, J.E.1    Xin, H.2    Tencza, M.3    Sherman, G.4    Dean, J.5    Bowden, S.6    Locarnini, S.7
  • 7
    • 2942532722 scopus 로고    scopus 로고
    • Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy
    • Werle-Lapostolle B, Bowden S, Locarnini S,Wursthorn K, Petersen J, Lau G, et al. Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy. Gastroenterology 2004; 126:1750-1758.
    • (2004) Gastroenterology , vol.126 , pp. 1750-1758
    • Werle-Lapostolle, B.1    Bowden, S.2    Locarnini, S.3    Wursthorn, K.4    Petersen, J.5    Lau, G.6
  • 8
    • 34548475512 scopus 로고    scopus 로고
    • Impaired intrahepatic hepatitis B virus productivity contributes to low viremia in most HBeAg-negative patients
    • Volz T, Lutgehetmann M, Wachtler P, Jacob A, Quaas A, Murray JM, et al. Impaired intrahepatic hepatitis B virus productivity contributes to low viremia in most HBeAg-negative patients. Gastroenterology 2007; 133:843-852.
    • (2007) Gastroenterology , vol.133 , pp. 843-852
    • Volz, T.1    Lutgehetmann, M.2    Wachtler, P.3    Jacob, A.4    Quaas, A.5    Murray, J.M.6
  • 9
    • 33748939050 scopus 로고    scopus 로고
    • Intrahepatic levels and replicative activity of covalently closed circular hepatitis B virus DNA in chronically infected patients
    • Laras A, Koskinas J, Dimou E, Kostamena A, Hadziyannis SJ. Intrahepatic levels and replicative activity of covalently closed circular hepatitis B virus DNA in chronically infected patients. Hepatology 2006; 44:694-702.
    • (2006) Hepatology , vol.44 , pp. 694-702
    • Laras, A.1    Koskinas, J.2    Dimou, E.3    Kostamena, A.4    Hadziyannis, S.J.5
  • 10
    • 0029838758 scopus 로고    scopus 로고
    • The hepatitis B virus persists for decades after patient's recovery from acute viral hepatitis despite active maintenance of a cytotoxic T-lymphocyte response
    • Rehermann B, Ferrari C, Pasquinelli C, Chisari FV. The hepatitis B virus persists for decades after patient's recovery from acute viral hepatitis despite active maintenance of a cytotoxic T-lymphocyte response. Nat Med 1996; 2:1104-1108.
    • (1996) Nat Med , vol.2 , pp. 1104-1108
    • Rehermann, B.1    Ferrari, C.2    Pasquinelli, C.3    Chisari, F.V.4
  • 11
    • 0031778788 scopus 로고    scopus 로고
    • Molecular basis for persistent hepatitis B virus infection in the liver after clearance of serum hepatitis B surface antigen
    • Mason AL, Xu L, Guo L, Kuhns M, Perrillo RP. Molecular basis for persistent hepatitis B virus infection in the liver after clearance of serum hepatitis B surface antigen. Hepatology 1998; 27:1736-1742.
    • (1998) Hepatology , vol.27 , pp. 1736-1742
    • Mason, A.L.1    Xu, L.2    Guo, L.3    Kuhns, M.4    Perrillo, R.P.5
  • 12
    • 33750964835 scopus 로고    scopus 로고
    • One-year entecavir or lamivudine therapy results in reduction of hepatitis B virus intrahepatic covalently closed circular DNA levels
    • Wong DK, Yuen MF, Ngai VW, Fung J, Lai CL. One-year entecavir or lamivudine therapy results in reduction of hepatitis B virus intrahepatic covalently closed circular DNA levels. Antivir Ther 2006; 11:909-916.
    • (2006) Antivir Ther , vol.11 , pp. 909-916
    • Wong, D.K.1    Yuen, M.F.2    Ngai, V.W.3    Fung, J.4    Lai, C.L.5
  • 13
    • 20444505037 scopus 로고    scopus 로고
    • Intrahepatic hepatitis B virus covalently closed circular DNA can be a predictor of sustained response to therapy
    • Sung JJ, Wong ML, Bowden S, Liew CT, Hui AY, Wong VW, et al. Intrahepatic hepatitis B virus covalently closed circular DNA can be a predictor of sustained response to therapy. Gastroenterology 2005; 128:1890-1897.
    • (2005) Gastroenterology , vol.128 , pp. 1890-1897
    • Sung, J.J.1    Wong, M.L.2    Bowden, S.3    Liew, C.T.4    Hui, A.Y.5    Wong, V.W.6
  • 14
    • 33748929265 scopus 로고    scopus 로고
    • Peginterferon alpha-2b plus adefovir induce strong cccDNA decline and HBsAg reduction in patients with chronic hepatitis B
    • Wursthorn K, Lutgehetmann M, Dandri M, Volz T, Buggisch P, Zollner B, et al. Peginterferon alpha-2b plus adefovir induce strong cccDNA decline and HBsAg reduction in patients with chronic hepatitis B. Hepatology 2006; 44:675-684.
    • (2006) Hepatology , vol.44 , pp. 675-684
    • Wursthorn, K.1    Lutgehetmann, M.2    Dandri, M.3    Volz, T.4    Buggisch, P.5    Zollner, B.6
  • 15
    • 4644296081 scopus 로고    scopus 로고
    • Quantitation of covalently closed circular hepatitis B virus DNA in chronic hepatitis B patients
    • Wong DK, Yuen MF, Yuan H, Sum SS, Hui CK, Hall J, Lai CL. Quantitation of covalently closed circular hepatitis B virus DNA in chronic hepatitis B patients. Hepatology 2004; 40:727-737.
    • (2004) Hepatology , vol.40 , pp. 727-737
    • Wong, D.K.1    Yuen, M.F.2    Yuan, H.3    Sum, S.S.4    Hui, C.K.5    Hall, J.6    Lai, C.L.7
  • 16
    • 0346055110 scopus 로고    scopus 로고
    • HBV cccDNA in patient's sera as an indicator for HBV reactivation and an early signal of liver damage
    • Chen Y, Sze J, He ML. HBV cccDNA in patient's sera as an indicator for HBV reactivation and an early signal of liver damage. World J Gastroenterol 2004; 10:82-85.
    • (2004) World J Gastroenterol , vol.10 , pp. 82-85
    • Chen, Y.1    Sze, J.2    He, M.L.3
  • 17
    • 66449095769 scopus 로고    scopus 로고
    • Validation of a sensitive and specific real-time PCR for detection and quantitation of hepatitis B virus covalently closed circular DNA in plasma of chronic hepatitis B patients
    • Takkenberg RB, Zaaijer HL, Molenkamp R, Menting S, Terpstra V,Weegink CJ, et al. Validation of a sensitive and specific real-time PCR for detection and quantitation of hepatitis B virus covalently closed circular DNA in plasma of chronic hepatitis B patients. J Med Virol 2009; 81:988-995.
    • (2009) J Med Virol , vol.81 , pp. 988-995
    • Takkenberg, R.B.1    Zaaijer, H.L.2    Molenkamp, R.3    Menting, S.4    Terpstra, V.5    Weegink, C.J.6
  • 19
    • 58149296156 scopus 로고    scopus 로고
    • EASL clinical practice guidelines: Management of chronic hepatitis B
    • European Association For The Study Of The Liver
    • European Association For The Study Of The Liver. EASL clinical practice guidelines: management of chronic hepatitis B. J Hepatol 2009; 50:227-242.
    • (2009) J Hepatol , vol.50 , pp. 227-242
  • 21
    • 0032894286 scopus 로고    scopus 로고
    • A highly sensitive assay for detection and quantitation of human cytomegalovirus DNA in serum and plasma by PCR and electrochemiluminescence
    • Boom R, Sol C, Weel J, Gerrits Y, De BM, Wertheim-van DP. A highly sensitive assay for detection and quantitation of human cytomegalovirus DNA in serum and plasma by PCR and electrochemiluminescence. J Clin Microbiol 1999; 37:1489-1497.
    • (1999) J Clin Microbiol , vol.37 , pp. 1489-1497
    • Boom, R.1    Sol, C.2    Weel, J.3    Gerrits, Y.4    De, B.M.5    Wertheim-Van, D.P.6
  • 22
    • 0026699493 scopus 로고
    • Detection of hepatitis C viral RNA sequences in fresh and paraffin-embedded liver biopsy specimens of non-A, non-B hepatitis patients
    • Bresters D, Cuypers HT, Reesink HW, Chamuleau RA, Schipper ME, Boeser-Nunnink BD, et al. Detection of hepatitis C viral RNA sequences in fresh and paraffin-embedded liver biopsy specimens of non-A, non-B hepatitis patients. J Hepatol 1992; 15:391-395.
    • (1992) J Hepatol , vol.15 , pp. 391-395
    • Bresters, D.1    Cuypers, H.T.2    Reesink, H.W.3    Chamuleau, R.A.4    Schipper, M.E.5    Boeser-Nunnink, B.D.6
  • 23
    • 0842276792 scopus 로고    scopus 로고
    • Anatomy and physiology of the liver
    • Zakim D, Boyer TD, editors Philidelphia: Elsevier Science
    • Saxena R, Zucker SD, Crawford JM. Anatomy and physiology of the liver. In: Zakim D, Boyer TD, editors. Hepatology; a textbook of liver disease. Philidelphia: Elsevier Science; 2003. pp. 3-30.
    • (2003) Hepatology; A Textbook of Liver Disease , pp. 3-30
    • Saxena, R.1    Zucker, S.D.2    Crawford, J.M.3
  • 24
  • 25
    • 33845722719 scopus 로고    scopus 로고
    • Quantitative analysis of HBV cccDNA from clinical specimens: Correlation with clinical and virological response during antiviral therapy
    • Bourne EJ, Dienstag JL, Lopez VA, Sander TJ, Longlet JM, Hall JG, et al. Quantitative analysis of HBV cccDNA from clinical specimens: correlation with clinical and virological response during antiviral therapy. J Viral Hepat 2007; 14:55-63.
    • (2007) J Viral Hepat , vol.14 , pp. 55-63
    • Bourne, E.J.1    Dienstag, J.L.2    Lopez, V.A.3    Sander, T.J.4    Longlet, J.M.5    Hall, J.G.6
  • 26
    • 36549058611 scopus 로고    scopus 로고
    • Serum hepatitis B surface antigen quantitation can reflect hepatitis B virus in the liver and predict treatment response
    • Chan HL, Wong VW, Tse AM, Tse CH, Chim AM, Chan HY, et al. Serum hepatitis B surface antigen quantitation can reflect hepatitis B virus in the liver and predict treatment response. Clin Gastroenterol Hepatol 2007; 5:1462-1468.
    • (2007) Clin Gastroenterol Hepatol , vol.5 , pp. 1462-1468
    • Chan, H.L.1    Wong, V.W.2    Tse, A.M.3    Tse, C.H.4    Chim, A.M.5    Chan, H.Y.6
  • 27
    • 33846473749 scopus 로고    scopus 로고
    • Hepatitis B virus-induced oncogenesis
    • Lupberger J, Hildt E. Hepatitis B virus-induced oncogenesis. World J Gastroenterol 2007; 13:74-81.
    • (2007) World J Gastroenterol , vol.13 , pp. 74-81
    • Lupberger, J.1    Hildt, E.2
  • 28
    • 59149088774 scopus 로고    scopus 로고
    • Intracellular levels of hepatitis B virus DNA and pregenomic RNA in peripheral blood mononuclear cells of chronically infected patients
    • Lu L, Zhang HY, Yueng YH, Cheung KF, Luk JM, Wang FS, Lau GK. Intracellular levels of hepatitis B virus DNA and pregenomic RNA in peripheral blood mononuclear cells of chronically infected patients. J Viral Hepat 2009; 16:104-112.
    • (2009) J Viral Hepat , vol.16 , pp. 104-112
    • Lu, L.1    Zhang, H.Y.2    Yueng, Y.H.3    Cheung, K.F.4    Luk, J.M.5    Wang, F.S.6    Lau, G.K.7
  • 29
    • 0030957914 scopus 로고    scopus 로고
    • Transcription of hepatitis B virus in peripheral blood mononuclear cells from persistently infected patients
    • Stoll-Becker S, Repp R, Glebe D, Schaefer S, Kreuder J, Kann M, et al. Transcription of hepatitis B virus in peripheral blood mononuclear cells from persistently infected patients. J Virol 1997; 71:5399-5407.
    • (1997) J Virol , vol.71 , pp. 5399-5407
    • Stoll-Becker, S.1    Repp, R.2    Glebe, D.3    Schaefer, S.4    Kreuder, J.5    Kann, M.6
  • 30
    • 0034235838 scopus 로고    scopus 로고
    • Molecular analysis of hepatitis B virus DNA in serum and peripheral blood mononuclear cells from hepatitis B surface antigen-negative cases
    • Cabrerizo M, Bartolome J, Caramelo C, Barril G, Carreno V. Molecular analysis of hepatitis B virus DNA in serum and peripheral blood mononuclear cells from hepatitis B surface antigen-negative cases. Hepatology 2000; 32:116-123.
    • (2000) Hepatology , vol.32 , pp. 116-123
    • Cabrerizo, M.1    Bartolome, J.2    Caramelo, C.3    Barril, G.4    Carreno, V.5
  • 31
    • 33750332486 scopus 로고    scopus 로고
    • Real-time PCR quantitation of hepatitis B virus total DNA and covalently closed circular DNA in peripheral blood mononuclear cells from hepatitis B virusinfected patients
    • Mazet-Wagner AA, Baclet MC, Loustaud-Ratti V, Denis F, Alain S. Real-time PCR quantitation of hepatitis B virus total DNA and covalently closed circular DNA in peripheral blood mononuclear cells from hepatitis B virusinfected patients. J Virol Methods 2006; 138:70-79.
    • (2006) J Virol Methods , vol.138 , pp. 70-79
    • Mazet-Wagner, A.A.1    Baclet, M.C.2    Loustaud-Ratti, V.3    Denis, F.4    Alain, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.