A novel strategy for therapeutic intervention for the genetic disease: Preventing proteolytic cleavage using small chemical compound

International Journal of Biochemistry and Cell Biology

Volumn 42, Issue 9, 2010, Pages 1401-1407

  Yamada, Masami ^a   Hirotsune, Shinji ^a   Wynshaw Boris, Anthony ^b  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Calpain inhibitor; Genetic disease; Haploinsufficiency; Lissencephaly; Protein augmentation

Indexed keywords

CALPAIN; DYNEIN ADENOSINE TRIPHOSPHATASE; KINESIN; 1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; MICROTUBULE ASSOCIATED PROTEIN; PAFAH1B1 PROTEIN, HUMAN;

AGYRIA; CELL TRANSPORT; CELLULAR DISTRIBUTION; GENE; GENE MUTATION; GENETIC DISORDER; LIS1 GENE; MICROTUBULE; NONHUMAN; PROTEIN DEGRADATION; SHORT SURVEY; ANIMAL; GENETIC DISEASES, INBORN; GENETICS; HUMAN; LISSENCEPHALY; METABOLISM; MOUSE;

1-ALKYL-2-ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; ANIMALS; DYNEINS; GENETIC DISEASES, INBORN; HUMANS; LISSENCEPHALY; MICE; MICROTUBULE-ASSOCIATED PROTEINS;

EID: 77955176430     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2010.05.017     Document Type: Short Survey

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