Variations in p53-like cDNA sequence are correlated with mussel haemic neoplasia: A potential molecular-level tool for biomonitoring

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 701, Issue 2, 2010, Pages 145-152

  Vassilenko, Ekaterina I ^a   Muttray, Annette F ^a   Schulte, Patricia M ^a   Baldwin, Susan A ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Biomonitoring; Bivalve mollusk; Haemic neoplasia; Leukemia; Mytilus; P53; Single nucleotide polymorphisms

Indexed keywords

BIOLOGICAL MARKER; COMPLEMENTARY DNA; PROTEIN P53;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOLOGICAL MONITORING; BIVALVE; CANADA; CODING; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA SEQUENCE; GENE LOCATION; GENETIC VARIABILITY; GENOTYPE; HEMIC NEOPLASIA; HEMOLYMPH; LEUKEMIA; MUSSEL; MYTILUS TROSSULUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC MUTATION; ANIMAL; BLOOD CELL; CYTOLOGY; GENETICS; TUMOR SUPPRESSOR GENE; ULTRASTRUCTURE;

ANIMALS; BASE SEQUENCE; BIVALVIA; DNA, COMPLEMENTARY; GENES, P53; HEMOCYTES; LEUKEMIA; POLYMORPHISM, SINGLE NUCLEOTIDE;

ANIMALIA; BIVALVIA; MYA; MYTILUS; MYTILUS TROSSULUS;

EID: 77955174142     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2010.06.001     Document Type: Article

References (56)

1. Gosling E. The Mussel Mytilus: Ecology, Physiology, Genetics and Culture 1992, Elsevier, Amsterdam.
2. Human Activity and the Environment: Annual Statistics 2006, Statistics Canada Environment Accounts and Statistics Division System of National Accounts, Ottawa.
3. Gosling E. Bivalve Mollusks. Biology, Ecology and Culture 2003, Wiley-Blackwell, Hoboken, NJ.
4. Gagné F., André C., Cejka P., Hausler R., Fournier M., Blaise C. Immunotoxic effects on freshwater mussels of a primary-treated wastewater before and after ozonation: A pilot plant study. Ecotoxicol. Environ. Saf. 2008, 69:366-373.
5. Calisi A., Lionetto M., Caricato R., Giordano M., Schettino T. Morphometric alterations in Mytilus galloprovincialis granulocytes: a new biomarker. Environ. Toxicol. Chem. 2008, 27:1435-1441.
6. Reinisch C.L., Charles A.M., Stone A.M. Epizootic neoplasia from softshell clams collected from New Bedford Harbour. Hazard. Waste 1984, 1:73-81.
7. St-Jean S.D., Stephens R.E., Courtenay S.C., Reinisch C.L. Detecting p53 family proteins in leukemia cells of Mytilus edulis from Pictou Harbour, Nova Scotia. Can. J. Fish. Aquat. Sci. 2005, 62:2055-2066.
8. Denslow N.D., Larkin P. Utilizing molecular technologies for bioindicator research. Environ. Bioindicators 2006, 1:40-59.
9. Bower S.M. The summer mortality syndrome and haemic neoplasia in the blue mussels (Mytilus edulis) from British Columbia. Can Techn Rep Fish Aquat Sci 1989, 1703:1-65.
10. Moore J.D. Pathogenesis of Disseminated Neoplasia in Eastern Pacific mussel Mytilus trossulus 1993, University of Washington, Seattle.
11. Gonzalez-Tizon A., Martinez-Lage A., Ausio J., Mendez J. Polyploidy in a natural population of mussel, Mytilus trossulus. Genome 2000, 43.
12. Moore J.D., Elston R.A., Drum A.S., Wilkinson M.T. Alternate pathogenesis of systemic neoplasia in the bivalve mollusc Mytilus. J Invertebr. Pathol. 1991, 58:231-243.
13. Farley C.A. Proliferative disorders in bivalve molluscs. Mar. Fish. Rev. 1976, 38:30-33.
14. Barber B.J. Neoplastic diseases of commercially important marine bivalves. Aquat. Living Resour. 2004, 17:449-466.
15. Bower S.M. Synopsis of Infectious Diseases and Parasites of Commercially Exploited Shellfish: Haemocytic Neoplasia of Mussels 2006.
16. Kelley M.L., Winge P., Heaney J.D., Stephens R.E., Farell J.H., Beneden R.J.V., Reinisch C.L., Lesser M.P., Walker C.W. Expression of homologues for p53 and p73 in the softshell clam (Mya arenaria), a naturally-occurring model for human cancer. Oncogene 2001, 20:748-758.
17. Muttray A.F, Schulte P.M., Baldwin S.A. Invertebrate p53-like mRNA isoforms are differentially expressed in mussel haemic neoplasia. Mar. Environ. Res. 2008, 66:412-421.
18. Cetin-Atalay R., Ozturk M. p53 mutations as fingerprints of environmental carcinogens. Pure Appl. Chem. 2000, 72:995-999.
19. Greenblatt M., Bennett W., Hollstein M., Harris C. Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis. Cancer Res. 1994, 54:4855-4878.
20. Kato S., Han S.-Y., Liu W., Otsuka H.S.K., Kanamaru R., Ishioka C. Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis. PNAS 2003, 100:8424-8429.
21. Cox R.L., Stephens R.E., Reinisch C.L. p63/73 homologues in surf clam: novel signaling motifs and implications for control of expression. Gene 2003, 320:49-58.
22. Jessen-Eller K., Kreiling J.A., Begley G.S., Steele M.E., Walker C.W., Stephens R.E., Reinisch C.L. A new invertebrate member of the p53 gene family is developmentally expressed and responds to polychlorinated biphenyls. Environ. Health Perspect. 2002, 110:377-385.
23. McGladdery S.E., Reinisch C.L., MacCallum G.S., Stephens R.E., Walker C.L., Davidson J.T. Haemic neoplasia in soft-shell clams (Mya arenaria): Recent outbreaks in Atlantic Canada and discovery of a p53 gene homologue associated with the condition. Bull. Aquacult. Assoc. Canada 2001, 101:19-26.
24. Muttray A.F., Cox R.L., St-Jean S.D., Poppelen P.v., Reinisch C.L., Baldwin S.A. Identification and phylogenetic comparison of p53 in two distinct mussel species (Mytilus), Comp. Biochem. Physiol. C. Toxicol. Pharmacol. 2005, 140:237-250.
25. Muttray A.F., Cox R.L., St-Jean S.D., Poppelen P.v., Reinisch C.L., Baldwin S.A. Identification of DeltaN isoform and polyadenylation site choice variants in molluscan p63/p73-like homologues. Mar. Biotechnol. 2007, 9:217-230.
26. Belyi V.A., Ak P., Markert E., Wang H., Hu W., Puzio-Kuter A., Levine A.J. The origins and evolution of the p53 family of genes. Cold Spring Harb. Perspect. Biol. 2010, 1-17.
27. Stifanic M., Micic M., Ramšak A., Blaškovic S., Ruso A., Zahn R.K., Batel R. p63 in Mytilus galloprovincialis and p53 family members in the phylum Mollusca. Comp. Biochem. Physiol. Part B 2009, 154:264-273.
28. Lu W.-J., Amatruda J.F., Abrams J.M. p53 ancestry: gazing through an evolutionary lens. Nat. Rev. Cancer 2009, 9:758-762.
29. Walker C., Bottger S., Low B. Mortalin-based cytoplasmic sequestration of p53 in a nonmammalian cancer model. Am. J. Pathol. 2006, 168:1526-1530.
30. Benard J., Douc-Rasy S., Ahomadegbe J.-C. Tp53 family members and human cancers. Hum. Mutat. 2003, 21:182-191.
31. Stephens R.E., Walker C.W., Reinisch C.L. Multiple protein differences distinguish clam leukemia cells from normal hemocytes: Evidence for the involvement of p53 homologues. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 2001, 129:329-338.
32. Concin N., Becker K., Slade N., Erster S., Mueller-Holzner E., Ulmer H., Daxenbichler G., Zeimet A., Zeillinger R., Marth C., Moll U. Transdominant DeltaTAp73 isoforms are frequently up-regulated in ovarian cancer. Evidence for their role as epigenetic p53 inhibitors in vivo. Cancer Res. 2004, 64:2449-2460.
33. Barker C.M., Calvert R.J., Walker C.W., Reinisch C.L. Detection of mutant p53 in clam leukemia cells. Exp. Cell Res. 1997, 232:240-245.
34. Heath D.D., Rawson P.D., Hilbish T.J. PCR-based nuclear markers identify alien blue mussel (Mytilus spp.) genotypes on the west coast of Canada. Can. J. Fish. Aquat. Sci. 1995, 52:2621-2627.
35. Dyrynda E.A., Pipe R.K., Ratcliffe N.A. Sub-populations of haemocytes in the adult and developing marine mussel. Cell Tissue Res. 1997, 289:527-536.
36. Cheng T.C. Bivalves. Invertebrate blood cells 1981, 233-300. Academic Press, New York, Chapter 8. N. Ratcliffe, A. Rowley (Eds.).
37. Pipe R.K., Farley S.R., Coles J.A. The separation and characterisation of haemocytes from the mussel Mytilus edulis. Cell Tissue Res. 1997, 289:537-545.
38. Hine P.M. The inter-relationships of bivalve haemocytes. Fish Shellfish Immunol. 1999, 9:367-385.
39. Pipe R.K. Differential binding of lectins to haemocytes of the mussel Mytilus edulis. Cell Tissue Res. 1990, 261:261-268.
40. Carballal M., Lopez M., Azevedo C., Villalba A. Hemolymph cell types of the mussel Mytilus galloprovincialis. Dis. Aquat. Org. 1997, 29:127-135.
41. Smolowitz R.M., Miosky D., Reinisch C.L. Ontogeny of leukemic cells of the soft shell clam. J. Invert. Pathol. 1989, 53:41-51.
42. Elston R.A., Kent M.L., Drum A.S. Progression, lethality and remission of hemic neoplasia in the bay mussel Mytilus edulis, Dis. Aquat. Org. 1988, 4:135-142.
43. Petitjean A., Mathe E., Kato S., Ishioka C., Tavtigian S., Hainaut P., Olivier M. Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: Lessons from recent developments in the IARC TP53 database. Hum. Mutat. 2007, 6:622-629.
44. Giaccia A., Kastan M. The complexity of p53 modulation: Emerging patterns from divergent signals. Genes Dev. 2006, 12:2973-2983.
45. Nedelcu A.M., Tan C. Early diversification and complex evolutionary history of the p53 tumor suppressor gene family. Dev. Genes. Evol. 2007, 217:801-806.
46. M.L. Kelley, C.W. Walker, R.J.V. Beneden. Accession number FJ041332, Direct Submission to Genbank, Submitted (13-AUG-2008) School of Marine Sciences, University of Maine, 5751 Murray Hall, Orono, ME 04469-5751, USA (2008).
47. Wheelan S.J., Church D.M., Ostell J.M. Spidey: a tool for mRNA-to-genomic alignments. Genome Res. 2001, 11:1952-1957.
48. Tiu R., Gondek L., O'Keefe C., Maciejewski J. Clonality of the stem cell compartment during evolution of myelodysplastic syndromes and other bone marrow failure syndromes. Leukemia 2007, 21:1648-1657.
49. Shabalina S., Ogurtsov A., Spiridonov N. A periodic pattern of mRNA secondary structure created by the genetic code. Nucleic Acids Res. 2006, 34:2428-2437.
50. Latchman D. Gene Regulation 2002, Nelson Thorns Ltd, Cheltenham, U.K.
51. Babendure J.R., Babendure J.L., Ding J.-H. Control of mammalian translation by mRNA structure near caps. RNA 2009, 12:851-861.
52. Chao H., Hsiao K., Su T. A silent mutation induces exon skipping in the phenylalanine hydroxylase gene in phenylketonuria. Hum. Genet. 2001, 108:14-19.
53. Bourdon J.-C., Fernandes K., Murray-Zmijewski F., Liu G., Diot A., Xirodimas D., Saville M., Lane D. p53 isoforms can regulate p53 transcriptional activity. Genes Dev. 2005, 19:2122-2137.
54. Kouidou S., Malousi A., Maglaveras N. Methylation and repeats in silent and nonsense mutations of p53. Mut. Res. 2006, 599:167-177.
55. Kouidou S., Agidou T., Kyrkou A., Andreou A., Katopodi T., Georgioua E., Krikelis D., Dimitriadou A., Spanos P., Tsilikas C., Destouni H., Tzimagiorgisa G. Non-CpG cytosine methylation of p53 exon 5 in non-small cell lung carcinoma. Lung Cancer 2005, 50:299-307.
56. Cortazzo P., Cerveñansky C., Marín M., Reiss C., Ehrlich R., Deana A. Silent mutations affect in vivo protein folding in Escherichia coli. Biochem. Biophys. Res. Commun. 2002, 293:537-541.