Immunotoxic effects on freshwater mussels of a primary-treated wastewater before and after ozonation: A pilot plant study

Ecotoxicology and Environmental Safety

Volumn 69, Issue 3, 2008, Pages 366-373

  Gagne F ^a   Andre C ^a   Cejka, P ^b   Hausler, R ^c   Fournier, M ^d   Blaise, C ^a  

^a ENVIRONMENT CANADA   (Canada)

^b Montreal Wastewater Treatment Plant   (Canada)

^c ÉCOLE DE TECHNOLOGIE SUPÉRIEURE   (Canada)

^d INRS INSTITUT ARMAND FRAPPIER   (Canada)

Author keywords

Hemocytes; Inflammation; Municipal wastewaters; Phagocytosis; Viability

Indexed keywords

FLUORESCEIN; NITRITE; POLYSTYRENE; PROSTAGLANDIN SYNTHASE;

BACTERIUM; BIVALVE; DISINFECTION; EFFLUENT; IMMUNOCOMPETENCE; OZONE; PATHOGEN; POLLUTION EFFECT; POLLUTION EXPOSURE; TOXICITY; WASTEWATER;

ARTICLE; BLOOD CELL; CELL ADHESION; CELL VIABILITY; CONCENTRATION RESPONSE; CYTOTOXICITY; DISINFECTION; EFFLUENT; ELLIPTIO COMPLANATA; ENZYME ACTIVITY; FRESHWATER SPECIES; HEMOLYMPH; IMMUNOCOMPETENCE; IMMUNOTOXICITY; MUSSEL; NONHUMAN; OZONATION; PHAGOCYTOSIS; PILOT STUDY; WASTE WATER; WASTE WATER MANAGEMENT;

ANIMALS; BIVALVIA; CELL SURVIVAL; FRESH WATER; HEMOCYTES; IMMUNOTOXINS; INFLAMMATION; OZONE; PHAGOCYTOSIS; PILOT PROJECTS; WASTE DISPOSAL, FLUID; WATER PURIFICATION;

ELLIPTIO COMPLANATA;

EID: 39749139768     PISSN: 01476513     EISSN: 10902414     Source Type: Journal    
DOI: 10.1016/j.ecoenv.2007.10.027     Document Type: Article

References (25)

1. Akaishi F.M., St Jean S.D., Biscay F., Clarke J., Rabitto S., and Oliveira Ribeiro C.A. Immunological responses, histopathological findings and disease resistance of blue mussels (Mytilus edulis) exposed to treated and untreated municipal wastewater. Aquat. Toxicol. 82 (2007) 1-14
2. Altman S.A., Randers L., and Rao G. Comparison of trypan blue dye exclusion and fluorometric assays for mammalian cell viability determinations. Biotechnol. Prog. 9 (1993) 671-674
3. Blaise C., Trottier S., Gagné F., Lallement C., and Hansen P.-D. Immunocompetence of bivalve hemocytes as evaluated by a miniaturized phagocytosis assay. Environ. Toxicol. 17 (2002) 160-169
4. Canesi L., Betti M., Ciacci C., Lorusso L.C., Gallo G., and Pruzzo C. Interactions between Mytilus haemocytes and different strains of Escherichia coli and Vibrio cholerae O1 El Tor: role of kinase-mediated signalling. Cell. Microbiol. 7 (2005) 667-674
5. Canesi L., Ciacci C., Lorusso L.C., Betti M., Guarnieri T., Tavolari S., and Gallo G. Immunomodulation by 17beta-estradiol in bivalve hemocytes. Am. J. Physio. Regul. Integr. Comp. Physiol. 291 (2006) 664-673
6. Canesi L., Lorusso L.C., Ciacci C., Betti M., Rocchi M., Pojana G., and Marcomini A. Immunomodulation of Mytilus hemocytes by individual estrogenic chemicals and environmentally relevant mixtures of estrogens: in vitro and in vivo studies. Aquat. Toxicol. 81 (2007) 36-44
7. Canesi L., Ciacci C., Lorusso L.C., Betti M., Gallo G., Pojana G., and Marcomini A. Effects of triclosan on Mytilus galloprovincialis hemocyte function and digestive gland enzyme activities: possible modes of action on non target organisms. Comp. Biochem. Physiol. 145C (2007) 464-472
8. Gagné F., and Blaise C. Estrogenic properties of municipal and industrial wastewaters evaluated with a rapid and sensitive chemoluminescent in situ hybridization assay (CISH) in rainbow trout hepatocytes. Aquat. Toxicol. 44 (1998) 83-91
9. Gagné F., Blaise C., Salazar M., Salazar S., and Hansen P.D. Evaluation of estrogenic effects of municipal effluents to the freshwater mussel Elliptio complanata. Comp. Biochem. Physiol. 128C (2001) 213-225
10. Gagné F., Berubé E., Fournier M., and Blaise C. Inflammatory properties of municipal effluents to Elliptio complanata mussels: lack of effects from anti-inflammatory drugs. Comp. Biochem. Physiol. 141C (2005) 332-337
11. Gagné F., Blaise C., Fournier M., and Hansen P.D. Effects of selected pharmaceutical products on phagocytic activity in Elliptio complanata mussels. Comp. Biochem. Physiol. 143C (2006) 179-186
12. Gagné F., André C., Cejka P., Gagnon C., and Blaise C. Toxicological effects of primary-treated urban wastewaters, before and after ozone treatment, on freshwater mussels (Elliptio complanata). Comp. Biochem. Physiol. 145C (2007) 542-552
13. Gauthier-Clerc S., Pellerin J., Fournier M., and Amiard J.C. Immunological and biochemical responses in Mya arenaria (Mollusca: Bivalvia) exposed in vivo to estradiol-17β. Comp. Biochem. Physiol. 144C (2006) 228-234
14. Gehr R., Wagner M., Veerasubramanian P., and Payment P. Disinfection efficiency of peracetic acid, UV and ozone after enhanced primary treatment of municipal wastewater. Water Res. 37 (2003) 4573-4586
15. Hed J. Methods for distinguishing ingested from adhering particles. Meth. Enzymol. 132 (1995) 198-204
16. Huggett D.B., Foran C.M., Brooks B.W., Weston J., Peterson B., Marsh K.E., La Point T.W., and Schlenk D. Comparison of in vitro and in vivo bioassays for estrogenicity in effluent from North American municipal wastewater facilities. Toxicol. Sci. 72 (2003) 77-83
17. Labreuche Y., Lambert C., Soudant P., Boule V., Huvet A., and Nicolas J.L. Cellular and molecular hemocyte responses of the Pacific oyster, Crassostrea gigas, following bacterial infection with Vibrio aestuarianus strain 01/32. Microbes Infect 8 (2006) 2715-2724
18. Lajeunesse A., and Gagnon C. Determination of acidic pharmaceutical products and carbamazepine in roughly primary-treated wastewater by solid-phase extraction and gas chromatography-tandem mass spectrometry. Int. J. Environ. Anal. Chem. 87 (2007) 565-578
19. Lorenzen A., and Kennedy S. A fluorescence-based protein assay for use with a microplate reader. Anal. Biochem. 214 (1993) 346-348
20. Metcalfe C.D., Koenig B.G., Bennie D.T., Servos M., Terns T.A., and Hirsch R. Occurrence of neutral and acidic drugs in the effluents of Canadian sewage treatment plants. Environ. Toxicol. Chem. 22 (2003) 2872-2880
21. Nieto-Fernandez F.E., Mattocks D., Cavany F., Salzet M., and Stefano G.B. Morphine coupling to invertebrate immunocyte nitric oxide release is dependent on intracellular calcium transients. Comp. Biochem. Physiol. 123B (1999) 295-299
22. Stefano G.B., Digenis A., Spector S., Leung M.K., Bilfinger T.V., Makman M.H., Scharrer B., and Abumrad N.N. Opiate-like substances in an invertebrate, an opiate receptor on invertebrate and human immunocytes, and a role in immunosuppression. Proc. Natl. Acad. Sci. USA 90 (1993) 11099-11103
23. Stefano G.B., Salzet M., and Magazine H.I. Cyclic nitric oxide release by human granulocytes, and invertebrate ganglia and immunocytes: nano-technological enhancement of amperometric nitric oxide determination. Med. Sci. Mon. 8 (2002) 199-204
24. Swietlik J., and Sikorska E. Application of fluorescence spectroscopy in the studies of natural organic matter fractions reactivity with chlorine dioxide and ozone. Water Res. 38 (2004) 3791-3799
25. Tafalla C., Novoa B., and Figueras A. Production of nitric oxide by mussel (Mytilus galloprovincialis) hemocytes and effect of exogenous nitric oxide on phagocytic functions. Comp. Biochem. Physiol. 132B (2002) 423-431