On the origin of the chemical barrier and tunneling in enzymes

Journal of Physical Organic Chemistry

Volumn 23, Issue 7, 2010, Pages 690-695

  MacHleder, Sara Quaytman ^a   Pineda, J R Exequiel T ^a   Schwartz, Steven D ^a,b  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b INSTITUT DES HAUTES ÉTUDES SCIENTIFIQUES   (France)

Author keywords

Conformational fluctuation; Free energy barrier; Potential energy; Promoting vibration

Indexed keywords

CHEMICAL BARRIERS; CHEMICAL FREE ENERGY; CONFIGURATION SPACE; CONFORMATIONAL FLUCTUATIONS; ENZYMATIC CATALYSIS; ENZYMATIC REACTION; EXPERIMENTAL GROUPS; FREE ENERGY SURFACE; HYDROGEN TRANSFER; LACTATE DEHYDROGENASE; THEORETICAL RESULT; TIGHT BINDING MODEL; TRANSITION STATE;

CATALYSIS; CATALYSTS; CONFORMATIONS; ENERGY BARRIERS; ENZYMES; POTENTIAL ENERGY; TUNNELING (EXCAVATION);

FREE ENERGY;

EID: 77955165752     PISSN: 08943230     EISSN: 10991395     Source Type: Journal    
DOI: 10.1002/poc.1688     Document Type: Article

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