Arginine methylation in subunits of mammalian pre-mRNA cleavage factor I

RNA

Volumn 16, Issue 8, 2010, Pages 1646-1659

  Martin, Georges ^a   Ostareck Lederer, Antje ^b   Chari, Ashwin ^c   Neuenkirchen, Nils ^c   Dettwiler, Sabine ^a   Blank, Diana ^a   Rüegsegger, Ursula ^a   Fischer, Utz ^c   Keller, Walter ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

CF Im; Mammalian cleavage factor I; PRMT1; PRMT2; PRMT5; Protein arginine methyltransferase

Indexed keywords

ARGININE; BINDING PROTEIN; CLEAVAGE FACTOR 1; MESSENGER RNA PRECURSOR; PROTEIN ARGININE METHYLTRANSFERASE; PROTEIN PABPN1; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PURIFICATION; GENE DELETION; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MASS SPECTROMETRY; METHYLATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PROCESSING; SITE DIRECTED MUTAGENESIS;

EID: 77955104829     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.2164210     Document Type: Article

References (60)

1. Bedford MT, Richard S. 2005. Arginine methylation an emerging regulator of protein function. Mol Cell 18: 263-272. (Pubitemid 41350532)
2. Bedford MT, Frankel A, Yaffe MB, Clarke S, Leder P, Richard S. 2000. Arginine methylation inhibits the binding of proline-rich ligands to Src homology 3, but not WW, domains. J Biol Chem 275: 16030-16036.
3. Berger I, Fitzgerald DJ, Richmond TJ. 2004. Baculovirus expression system for heterologous multiprotein complexes. Nat Biotechnol 22: 1583-1587.
4. Boisvert FM, Cote J, Boulanger MC, Richard S. 2003. A proteomic analysis of arginine-methylated protein complexes. Mol Cell Proteomics 2: 1319-1330.
5. Branscombe TL, Frankel A, Lee JH, Cook JR, Yang Z, Pestka S, Clarke S. 2001. PRMT5 (Janus kinase-binding protein 1) catalyzes the formation of symmetric dimethylarginine residues in proteins. J Biol Chem 276: 32971-32976.
6. Brown KM, Gilmartin GM. 2003. A mechanism for the regulation of pre-mRNA 39 processing by human cleavage factor Im. Mol Cell 12: 1467-1476.
7. Cardinale S, Cisterna B, Bonetti P, Aringhieri C, Biggiogera M, Barabino SM. 2007. Subnuclear localization and dynamics of the pre-mRNA 3′ end processing factor mammalian cleavage factor I 68-kDa subunit. Mol Biol Cell 18: 1282-1292.
8. Chari A, Golas MM, Klingenhager M, Neuenkirchen N, Sander B, Englbrecht C, Sickmann A, Stark H, Fischer U. 2008. An assembly chaperone collaborates with the SMN complex to generate spliceosomal snRNPs. Cell 135: 497-509.
9. Chen D, Ma H, Hong H, Koh SS, Huang SM, Schurter BT, Aswad DW, Stallcup MR. 1999. Regulation of transcription by a protein methyltransferase. Science 284: 2174-2177.
10. Colgan DF, Murthy KG, Prives C, Manley JL. 1996. Cell-cycle related regulation of poly(A) polymerase by phosphorylation. Nature 384: 282-285. (Pubitemid 26396981)
11. Cook JR, Lee JH, Yang ZH, Krause CD, Herth N, Hoffmann R, Pestka S. 2006. FBXO11/PRMT9, a new protein arginine methyltransferase, symmetrically dimethylates arginine residues. Biochem Biophys Res Commun 342: 472-481.
12. m. Nucleic Acids Res 36: 3474-3483.
13. m contains homologs of yeast proteins and bridges two other cleavage factors. EMBO J 19: 5895-5904.
14. m mediate RNA binding, protein-protein interactions, and subcellular localization. J Biol Chem 279: 35788-35797.
15. Dignam JD, Lebovitz RM, Roeder RG. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11: 1475-1489.
16. Frankel A, Yadav N, Lee J, Branscombe TL, Clarke S, Bedford MT. 2002. The novel human protein arginine N-methyltransferase PRMT6 is a nuclear enzyme displaying unique substrate specificity. J Biol Chem 277: 3537-3543.
17. Friesen WJ, Wyce A, Paushkin S, Abel L, Rappsilber J, Mann M, Dreyfuss G. 2002. A novel WD repeat protein component of the methylosome binds Sm proteins. J Biol Chem 277: 8243-8247. (Pubitemid 34968281)
18. Fronz K, Otto S, Kolbel K, Kühn U, Friedrich H, Schierhorn A, Beck-Sickinger AG, Ostareck-Lederer A, Wahle E. 2008. Promiscuous modification of the nuclear poly(A)-binding protein by multiple protein-arginine methyltransferases does not affect the aggregation behavior. J Biol Chem 283: 20408-20420.
19. Graveley BR. 2000. Sorting out the complexity of SR protein functions. RNA 6: 1197-1211.
20. Gunderson SI, Beyer K, Martin G, Keller W, Boelens WC, Mattaj LW. 1994. The human U1A snRNP protein regulates polyadenylation via a direct interaction with poly(A) polymerase. Cell 76: 531-541. (Pubitemid 24064173)
21. Gunderson SI, Polycarpou-Schwarz M, Mattaj IW. 1998. U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase. Mol Cell 1: 255-264.
22. Herrmann F, Lee J, Bedford MT, Fackelmayer FO. 2005. Dynamics of human protein arginine methyltransferase 1(PRMT1) in vivo. J Biol Chem 280: 38005-38010.
23. Ingham RJ, Colwill K, Howard C, Dettwiler S, Lim CS, Yu J, Hersi K, Raaijmakers J, Gish G, Mbamalu G, et al. 2005. WW domains provide a platform for the assembly of multiprotein networks. Mol Cell Biol 25: 7092-7106.
24. Jenny A, Keller W. 1995. Cloning of cDNAs encoding the 160 kDa subunit of the bovine cleavage and polyadenylation specificity factor. Nucleic Acids Res 23: 2629-2635.
25. Kaufmann I, Martin G, Friedlein A, Langen H, Keller W. 2004. Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase. EMBO J 23: 616-626. (Pubitemid 38282393)
26. Kühn U, Nemeth A, Meyer S, Wahle E. 2003. The RNA binding domains of the nuclear poly(A)-binding protein. J Biol Chem 278: 16916-16925.
27. Kühn U, Gundel M, Knoth A, Kerwitz Y, Rudel S, Wahle E. 2009. Poly(A) tail length is controlled by the nuclear poly(A)-binding protein regulating the interaction between poly(A) polymerase and the cleavage and polyadenylation specificity factor. J Biol Chem 284: 22803-22814.
28. Kyburz A, Friedlein A, Langen H, Keller W. 2006. Direct interactions between subunits of CPSF and the U2 snRNP contribute to the coupling of pre-mRNA 3′ end processing and splicing. Mol Cell 23: 195-205.
29. Lakowski TM, Frankel A. 2009. Kinetic analysis of human protein arginine N-methyltransferase 2: Formation of monomethyl- and asymmetric dimethyl-arginine residues on histone H4. Biochem J 421: 253-261.
30. Lee YH, Stallcup MR. 2009. Minireview: Protein arginine methylation of nonhistone proteins in transcriptional regulation. Mol Endocrinol 23: 425-433.
31. Lee J, Sayegh J, Daniel J, Clarke S, Bedford MT. 2005a. PRMT8, a new membrane-bound tissue-specific member of the protein arginine methyltransferase family. J Biol Chem 280: 32890-32896.
32. Lee JH, Cook JR, Yang ZH, Mirochnitchenko O, Gunderson SI, Felix AM, Herth N, Hoffmann R, Pestka S. 2005b. PRMT7, a new protein arginine methyltransferase that synthesizes symmetric dimethylarginine. J Biol Chem 280: 3656-3664.
33. Lin WJ, Gary JD, Yang MC, Clarke S, Herschman HR. 1996. The mammalian immediate-early TIS21 protein and the leukemiaassociated BTG1 protein interact with a protein-arginine N-methyltransferase. J Biol Chem 271: 15034-15044.
34. Martin G, Keller W. 2007. RNA-specific ribonucleotidyl transferases. RNA 13: 1834-1849.
35. Meister G, Eggert C, Buhler D, Brahms H, Kambach C, Fischer U. 2001. Methylation of Sm proteins by a complex containing PRMT5 and the putative U snRNP assembly factor pICln. Curr Biol 11: 1990-1994.
36. Meister G, Eggert C, Fischer U. 2002. SMN-mediated assembly of RNPs: A complex story. Trends Cell Biol 12: 472-478. (Pubitemid 35346518)
37. Miranda TB, Miranda M, Frankel A, Clarke S. 2004. PRMT7 is a member of the protein arginine methyltransferase family with a distinct substrate specificity. J Biol Chem 279: 22902-22907.
38. Neuenkirchen N, Chari A, Fischer U. 2008. Deciphering the assembly pathway of Sm-class U snRNPs. FEBS Lett 582: 1997-2003.
39. Nicholson TB, Chen T, Richard S. 2009. The physiological and pathophysiological role of PRMT1-mediated protein arginine methylation. Pharmacol Res 60: 466-474.
40. Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M. 2006. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell 127: 635-648.
41. Ostareck-Lederer A, Ostareck DH, Rucknagel KP, Schierhorn A, Moritz B, Huttelmaier S, Flach N, Handoko L, Wahle E. 2006. Asymmetric arginine dimethylation of heterogeneous nuclear ribonucleoprotein K by protein-arginine methyltransferase 1 inhibits its interaction with c-Src. J Biol Chem 281: 11115-11125.
42. Pahlich S, Zakaryan RP, Gehring H. 2006. Protein arginine methylation: Cellular functions and methods of analysis. Biochim Biophys Acta 1764: 1890-1903.
43. Pawlak MR, Scherer CA, Chen J, Roshon MJ, Ruley HE. 2000. Arginine N-methyltransferase 1 is required for early postimplantation mouse development, but cells deficient in the enzyme are viable. Mol Cell Biol 20: 4859-4869.
44. Qi C, Chang J, Zhu Y, Yeldandi AV, Rao SM, Zhu YJ. 2002. Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor alpha. J Biol Chem 277: 28624-28630.
45. Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, et al. 2005. Towards a proteome-scale map of the human protein-protein interaction network. Nature 437: 1173-1178.
46. m involved in the 3′ end processing of messenger RNA precursors. J Biol Chem 271: 6107-6113.
47. m is related to spliceosomal SR proteins and can be reconstituted in vitro from recombinant subunits. Mol Cell 1: 243-253.
48. m68 functions in mRNA export. Mol Biol Cell 20: 5211-5223.
49. Ryan K, Bauer DL. 2008. Finishing touches: Post-translational modification of protein factors involved in mammalian premRNA 3′ end formation. Int J Biochem Cell Biol 40: 2384-2396.
50. Shen EC, Henry MF, Weiss VH, Valentini SR, Silver PA, Lee MS. 1998. Arginine methylation facilitates the nuclear export of hnRNP proteins. Genes Dev 12: 679-691.
51. Shi Y, Di Giammartino DC, Taylor D, Sarkeshik A, Rice WJ, Yates JR 3rd, Frank J, Manley JL. 2009. Molecular architecture of the human pre-mRNA 3′ processing complex. Mol Cell 33: 365-376.
52. Shimazu T, Horinouchi S, Yoshida M. 2007. Multiple histone deacetylases and the CREB-binding protein regulate pre-mRNA 3′-end processing. J Biol Chem 282: 4470-4478.
53. Smith JJ, Rucknagel KP, Schierhorn A, Tang J, Nemeth A, Linder M, Herschman HR, Wahle E. 1999. Unusual sites of arginine methylation in poly(A)-binding protein II and in vitro methylation by protein arginine methyltransferases PRMT1 and PRMT3. J Biol Chem 274: 13229-13234.
54. Tang J, Gary JD, Clarke S, Herschman HR. 1998. PRMT3, a type I protein arginine N-methyltransferase that differs from PRMT1 in its oligomerization, subcellular localization, substrate specificity, and regulation. J Biol Chem 273: 16935-16945.
55. Vagner S, Vagner C, Mattaj IW. 2000. The carboxyl terminus of vertebrate poly(A) polymerase interacts with U2AF 65 to couple 3′-end processing and splicing. Genes Dev 14: 403-413. (Pubitemid 30131886)
56. Venkataraman K, Brown KM, Gilmartin GM. 2005. Analysis of a noncanonical poly(A) site reveals a tripartite mechanism for vertebrate poly(A) site recognition. Genes Dev 19: 1315-1327.
57. Vethantham V, Rao N, Manley JL. 2008. Sumoylation regulates multiple aspects of mammalian poly(A) polymerase function. Genes Dev 22: 499-511.
58. Wahle E, Keller W. 1996. The biochemistry of polyadenylation. Trends Biochem Sci 21: 247-250.
59. Wolf SS. 2009. The protein arginine methyltransferase family: An update about function, new perspectives and the physiological role in humans. Cell Mol Life Sci 66: 2109-2121.
60. Zhao J, Hyman L, Moore C. 1999. Formation of mRNA 3′ ends in eukaryotes: Mechanism, regulation, and interrelationships with other steps in mRNA synthesis. Microbiol Mol Biol Rev 63: 405-445. (Pubitemid 29264977)