Effects of sphingosylphosphorylcholine against cholestatic oxidative stress and liver damage in the common bile duct ligated rats

Journal of Pediatric Surgery

Volumn 44, Issue 4, 2009, Pages 702-710

  Aksu, Burhan ^a   Umit, Hasan ^a   Kanter, Mehmet ^a   Guzel, Ahmet ^a   Inan, Mustafa ^a   Civelek, Sabiha ^b   Aktas, Cevat ^a   Uzun, Hafize ^b  

^a TRAKYA UNIVERSITY   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Bile duct ligation; Extrahepatic cholestasis; Impaired bile flow; Lipid peroxidation; Oxidative stress; SPC

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA SMOOTH MUSCLE ACTIN; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; BILIRUBIN GLUCURONIDE; COLLAGEN; GAMMA GLUTAMYLTRANSFERASE; HYDROXYPROLINE; MALONALDEHYDE; MYELOPEROXIDASE; NITRIC OXIDE; SPHINGOSYLPHOSPHORYLCHOLINE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT LIGATION; BILIRUBIN BLOOD LEVEL; BIOACCUMULATION; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFECT; ENZYME ACTIVITY; EXTRAHEPATIC BILE DUCT OBSTRUCTION; HEPATITIS; HISTOPATHOLOGY; LEUKOCYTE ACTIVATION; LIVER CELL; LIVER HISTOLOGY; LIVER INJURY; LIVER PROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANALYSIS OF VARIANCE; ANIMALS; CHOLESTASIS, EXTRAHEPATIC; COMMON BILE DUCT; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; IMMUNOHISTOCHEMISTRY; LIGATION; LIPID PEROXIDATION; LIVER DISEASES; LIVER FUNCTION TESTS; MALE; MALONDIALDEHYDE; NITRIC OXIDE; OXIDATIVE STRESS; PHOSPHORYLCHOLINE; PROBABILITY; RANDOM ALLOCATION; RATS; RATS, WISTAR; REFERENCE VALUES; SENSITIVITY AND SPECIFICITY; SPHINGOSINE;

EID: 63649129338     PISSN: 00223468     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpedsurg.2008.09.016     Document Type: Article

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