Behavioral sequelae following acute diisopropylfluorophosphate intoxication in rats: Comparative effects of atropine and cannabinomimetics

Neurotoxicology and Teratology

Volumn 32, Issue 3, 2010, Pages 329-335

  Wright, Linnzi K M ^a   Liu, Jing ^a   Nallapaneni, Anuradha ^a   Pope, Carey N ^a  

^a OKLAHOMA STATE UNIVERSITY   (United States)

Author keywords

Atropine; Diisopropylfluorophosphate (DFP); Elevated plus maze; Fatty acid amide hydrolase (FAAH); Forced swimming test; Monoacylglycerol lipase (MAGL); Motor activity; URB597; URB602

Indexed keywords

ATROPINE; BIPHENYL 3 YLCARBAMIC ACID CYCLOHEXYL ESTER; CANNABINOID RECEPTOR AGONIST; CHOLINESTERASE; CYCLOHEXYLCARBAMIC ACID 3' CARBAMOYLBIPHENYL 3 YL ESTER; DYFLOS; UNCLASSIFIED DRUG; URB 602;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY DISORDER; ARTICLE; BRAIN REGION; CHOLINESTERASE INHIBITION; CONTROLLED STUDY; DEPRESSION; DRUG MECHANISM; ENZYME ACTIVITY; FORCED SWIMMING TEST; MALE; MAZE TEST; MOTOR ACTIVITY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; WEIGHT REDUCTION;

ANIMALS; ATROPINE; BEHAVIOR, ANIMAL; BENZAMIDES; BIPHENYL COMPOUNDS; BRAIN; CARBAMATES; CHOLINESTERASE INHIBITORS; CHOLINESTERASES; ENDOCANNABINOIDS; ISOFLUROPHATE; MALE; MAZE LEARNING; MOTOR ACTIVITY; RATS; RATS, SPRAGUE-DAWLEY; SWIMMING;

RATTUS;

EID: 77951205497     PISSN: 08920362     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ntt.2009.12.006     Document Type: Article

References (62)

1. Adamczyk P., Golda A., McCreary A.C., Filip M., Przegalinski E. Activation of endocannabinoid transmission induces antidepressant-like effects in rats. J. Physiol. Pharmacol. 2008, 59:217-228.
2. Assini F.L., Zanette K.D., Brocardo P.S., Pandolfo P., Rodrigues A.L., Takahashi R.N. Behavioral effects and ChE measures after acute and repeated administration of malathion in rats. Environ. Toxicol Pharmacol. 2005, 20:443-449.
3. Bowden C.A., Krenzelok E.P. Clinical applications of commonly used contemporary antidotes. A US perspective. Drug Saf. 1997, 16:9-47.
4. Cheer J.F., Wassum K.M., Sombers L.A., Heien M.L., Ariansen J.L., Aragona B.J., Phillips P.E., Wightman R.M. Phasic dopamine release evoked by abused substances requires cannabinoid receptor activation. J. Neurosci. 2007, 27:791-795.
5. Cheng A.T., Chen T.H., Chen C.C., Jenkins R. Psychosocial and psychiatric risk factors for suicide. Case-control psychological autopsy study. Br. J. Psychiatry. 2000, 177:360-365.
6. Colosio C., Tiramani M., Maroni M. Neurobehavioral effects of pesticides: state of the art. Neurotoxicology 2003, 24:577-591.
7. Cota D., Marsicano G., Tschop M., Grubler Y., Flachskamm C., Schubert M., Auer D., Yassouridis A., Thone-Reineke C., Ortmann S., et al. The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. Clin. Invest. 2003, 112:423-431.
8. de Silva H.J., Wijewickrema R., Senanayake N. Does pralidoxime affect outcome of management in acute organophosphorus poisoning?. Lancet 1992, 339:113-1138.
9. Degroot A., Kofalvi A., Wade M.R., Davis R.J., Rodrigues R.J., Rebola N., Cunha R.A., Nomikos G.G. CB1 receptor antagonism increases hippocampal acetylcholine release: site and mechanism of action. Mol. Pharmacol. 2006, 70:1236-1245.
10. Delgado E., McConnell R., Miranda J., Keifer M., Lundberg I., Partanen T., Wesseling C. Central nervous system effects of acute organophosphate poisoning in a two-year follow-up. Scand. J. Work Environ. Health 2004, 30:362-370.
11. Detke M.J., Rickels M., Lucki I. Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants. Psychopharmacology 1995, 121:66-72.
12. Eddleston M., Buckley N.A., Eyer P., Dawson A.H. Management of acute organophosphorus pesticide poisoning. Lancet 2008, 371:597-607.
13. Fegley D., Gaetani S., Duranti A., Tontini A., Mor M., Tarzia G., Piomelli D. Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3′-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation. J. Pharmacol. Exp. Ther. 2005, 313:352-358.
14. Fride E. Endocannabinoids in the central nervous system-an overview. Prostaglandins Leukot. Essent. Fatty Acids 2002, 66:221-233.
15. Gifford A.N., Ashby C.R. Electrically evoked acetylcholine release from hippocampal slices is inhibited by the cannabinoid receptor agonist, WIN 55212-2, and is potentiated by the cannabinoid antagonist, SR 141716A. J. Pharmacol. Exp. Ther. 1996, 277:1431-1436.
16. Glowinski J., Iversen L.L. Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain. J. Neurochem. 1966, 13:655-669.
17. Gobbi G., Bambico F.R., Mangieri R., Bortolato M., Campolongo P., Solinas M., Cassano T., Morgese M.G., Debonnel G., Duranti A., et al. Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:18620-18625.
18. Hill M.N., Miller G.E., Ho W.S., Gorzalka B.B., Hillard C.J. Serum endocannabinoid content is altered in females with depressive disorders: a preliminary report. Pharmacopsychiatry 2008, 41:48-53.
19. Hungund B.L., Vinod K.Y., Kassir S.A., Basavarajappa B.S., Yalamanchili R., Cooper T.B., Mann J.J., Arango V. Upregulation of CB1 receptors and agonist-stimulated [35S]GTPgammaS binding in the prefrontal cortex of depressed suicide victims. Mol. Psychiatry. 2004, 9:184-190.
20. Inskip H.M., Harris E.C., Barraclough B. Lifetime risk of suicide for affective disorder, alcoholism and schizophrenia. Br. J. Psychiatry 1998, 172:35-37.
21. Jaga K., Dharmani C. The interrelation between organophosphate toxicity and the epidemiology of depression and suicide. Rev. Environ. Health 2007, 22:57-73.
22. Johnson C.D., Russell R.L. A rapid, simple radiometric assay for cholinesterase, suitable for multiple determinations. Anal. Biochem. 1975, 64:229-238.
23. Kathuria S., Gaetani S., Fegley D., Valino F., Duranti A., Tontini A., Mor M., Tarzia G., La Rana G., Calignano A., et al. Modulation of anxiety through blockade of anandamide hydrolysis. Nat. Med. 2003, 9:76-81.
24. Kiely T., Donaldson D., Grube A. Pesticides industry sales and usage: 2000 and 2001 market estimates. U.S. Environmental Protection Agency 2004.
25. King A.R., Duranti A., Tontini A., Rivara S., Rosengarth A., Clapper J.R., Astarita G., Geaga J.A., Luecke H., Mor M., et al. URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices. Chem Biol 2007, 14:1357-1365.
26. Levenes C., Daniel H., Soubrie P., Crepel F. Cannabinoids decrease excitatory synaptic transmission and impair long-term depression in rat cerebellar Purkinje cells. J. Physiol. 1998, 510(Pt 3):867-879.
27. London L., Flisher A.J., Wesseling C., Mergler D., Kromhout H. Suicide and exposure to organophosphate insecticides: cause or effect?. Am. J. Ind. Med. 2005, 47:308-321.
28. Lotti M. Treatment of acute organophosphate poisoning. Med. J. Aust. 1991, 154:51-55.
29. Lucki I. The forced swimming test as a model for core and component behavioral effects of antidepressant drugs. Behav. Pharmacol. 1997, 8:523-532.
30. Mancinelli A., Borsini F., d'Aranno V., Lecci A., Meli A. Cholinergic drug effects on antidepressant-induced behaviour in the forced swimming test. Eur. J. Pharmacol. 1988, 158:199-205.
31. Marrs T.C., Vale J.A. Management of organophosphorus pesticide poisoning. Toxicology of organophosphate and carbamate compounds 2006, 715-734. Elsevier Academic Press, Amsterdam. R.C. Gupta (Ed.).
32. Martin M., Ledent C., Parmentier M., Maldonado R., Valverde O. Involvement of CB1 cannabinoid receptors in emotional behaviour. Psychopharmacology 2002, 159:379-387.
33. Michelsen K.A., Prickaerts J., Steinbusch H.W. The dorsal raphe nucleus and serotonin: implications for neuroplasticity linked to major depression and Alzheimer's disease. Prog. Brain Res. 2008, 172:233-264.
34. Miller A.S., Walker J.M. Effects of a cannabinoid on spontaneous and evoked neuronal activity in the substantia nigra pars reticulata. Eur. J. Pharmacol. 1995, 279:179-185.
35. Millis R.M., Archer P.W., Whittaker J.A., Trouth C.O. The role of hypoxia in organophosphorus nerve agent intoxication. Neurotoxicology 1988, 9:273-285.
36. Moser V.C., McCormick J.P., Creason J.P., MacPhail R.C. Comparison of chlordimeform and carbaryl using a functional observational battery. Fundam. Appl. Toxicol. 1988, 11:189-206.
37. Nakazi M., Bauer U., Nickel T., Kathmann M., Schlicker E. Inhibition of serotonin release in the mouse brain via presynaptic cannabinoid CB1 receptors. Naunyn Schmiedebergs Arch. Pharmacol. 2000, 361:19-24.
38. Nallapaneni A., Liu J., Karanth S., Pope C. Modulation of paraoxon toxicity by the cannabinoid receptor agonist WIN 55, 212-2. Toxicology 2006, 227:173-183.
39. Nallapaneni A., Liu J., Karanth S., Pope C. Pharmacological enhancement of endocannabinoid signaling reduces the cholinergic toxicity of diisopropylfluorophosphate. Neurotoxicology 2008, 29:1037-1043.
40. Nomura D.K., Blankman J.L., Simon G.M., Fujioka K., Issa R.S., Ward A.M., Cravatt B.F., Casida J.E. Activation of the endocannabinoid system by organophosphorus nerve agents. Nat. Chem. Biol. 2008, 4:373-378.
41. Page M.E., Detke M.J., Dalvi A., Kirby L.G., Lucki I. Serotonergic mediation of the effects of fluoxetine, but not desipramine, in the rat forced swimming test. Psychopharmacology 1999, 147:162-167.
42. Pellow S., Chopin P., File S.E., Briley M. Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J. Neurosci. Methods 1985, 14:149-167.
43. Quistad G.B., Liang S.N., Fisher K.J., Nomura D.K., Casida J.E. Each lipase has a unique sensitivity profile for organophosphorus inhibitors. Toxicol. Sci. 2006, 91:166-172.
44. Quistad G.B., Sparks S.E., Casida J.E. Fatty acid amide hydrolase inhibition by neurotoxic organophosphorus pesticides. Toxicol. Appl. Pharmacol. 2001, 173:48-55.
45. Quistad G.B., Sparks S.E., Segall Y., Nomura D.K., Casida J.E. Selective inhibitors of fatty acid amide hydrolase relative to neuropathy target esterase and acetylcholinesterase: toxicological implications. Toxicol. Appl. Pharmacol. 2002, 179:57-63.
46. Roberts R.E., Lee E.S. Occupation and the prevalence of major depression, alcohol, and drug abuse in the United States. Environ. Res. 1993, 61:266-278.
47. Rodriguez de Fonseca F., Del Arco I., Bermudez-Silva F.J., Bilbao A., Cippitelli A., Navarro M. The endocannabinoid system: physiology and pharmacology. Alcohol Alcohol. 2005, 40:2-14.
48. Rosenstock L., Keifer M., Daniell W.E., McConnell R., Claypoole K. Chronic central nervous system effects of acute organophosphate pesticide intoxication. The Pesticide Health Effects Study Group. Lancet 1991, 338:223-227.
49. Sanchez-Amate M.C., Flores P., Sanchez-Santed F. Effects of chlorpyrifos in the plus-maze model of anxiety. Behav. Pharmacol. 2001, 12:285-292.
50. Sanchis-Segura C., Cline B.H., Marsicano G., Lutz B., Spanagel R. Reduced sensitivity to reward in CB1 knockout mice. Psychopharmacology 2004, 176:223-232.
51. Sanne B., Mykletun A., Moen B.E., Dahl A.A., Tell G.S. Farmers are at risk for anxiety and depression: the Hordaland Health Study. Occup. Med. 2004, 54:92-100.
52. Savage E.P., Keefe T.J., Mounce L.M., Heaton R.K., Lewis J.A., Burcar P.J. Chronic neurological sequelae of acute organophosphate pesticide poisoning. Arch. Environ. Health 1988, 43:38-45.
53. Schlicker E., Timm J., Zentner J., Gothert M. Cannabinoid CB1 receptor-mediated inhibition of noradrenaline release in the human and guinea-pig hippocampus. Naunyn Schmiedebergs Arch. Pharmacol. 1997, 356:583-589.
54. Schulz H., Desi I., Nagymajtenyi L. Behavioral effects of subchronic intoxication with parathion-methyl in male Wistar rats. Neurotoxicol. Teratol. 1990, 12:125-127.
55. Shen M., Piser T.M., Seybold V.S., Thayer S.A. Cannabinoid receptor agonists inhibit glutamatergic synaptic transmission in rat hippocampal cultures. J. Neurosci. 1996, 16:4322-4334.
56. Sirkka U., Nieminen S.A., Ylitalo P. Neurobehavioral toxicity with low doses of sarin and soman. Methods Find. Exp. Clin. Pharmacol. 1990, 12:245-250.
57. Stallones L., Beseler C. Pesticide poisoning and depressive symptoms among farm residents. Ann. Epidemiol. 2002, 12:389-394.
58. Steenland K., Jenkins B., Ames R.G., O'Malley M., Chrislip D., Russo J. Chronic neurological sequelae to organophosphate pesticide poisoning. Am. J. Public Health 1994, 84:731-736.
59. Steffens M., Engler C., Zentner J., Feuerstein T.J. Cannabinoid CB1 receptor-mediated modulation of evoked dopamine release and of adenylyl cyclase activity in the human neocortex. Br. J. Pharmacol. 2004, 141:1193-1203.
60. Tzavara E.T., Wade M., Nomikos G.G. Biphasic effects of cannabinoids on acetylcholine release in the hippocampus: site and mechanism of action. J. Neurosci. 2003, 23:9374-9384.
61. Valvassori S.S., Fortunato J.J., Gomes K.M., Reus G.Z., Martins M.R., Gavioli E.C., Schetinger M.R., Dal-Pizzol F., Quevedo J. Acute and subacute exposure to malathion impairs aversive but not non-associative memory in rats. Neurotox. Res. 2007, 12:71-79.
62. Wesseling C., Keifer M., Ahlbom A., McConnell R., Moon J.D., Rosenstock L., Hogstedt C. Long-term neurobehavioral effects of mild poisonings with organophosphate and n-methyl carbamate pesticides among banana workers. Int. J. Occup. Environ. Health 2002, 8:27-34.