The sphingosine-1-phosphate pathway is upregulated in response to partial urethral obstruction in male rats and activates RhoA/Rho-kinase signalling

BJU International

Volumn 106, Issue 4, 2010, Pages 562-571

  Aydin, Memduh ^a   Downing, Keith ^a   Villegas, Guillermo ^a   Zhang, Xinhua ^a   Chua, Rowena ^a   Melman, Arnold ^a   Disanto, Michael E ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

bladder; outlet obstruction; Rho kinase; sphingosine 1 phosphate

Indexed keywords

MESSENGER RNA; RECOMBINANT ENZYME; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; LYSOPHOSPHOLIPID; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CROSS LINKING; ENZYME ACTIVATION; GENETIC TRANSFECTION; IN VITRO STUDY; MALE; NONHUMAN; OVERACTIVE BLADDER; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE CONTRACTION; UPREGULATION; URETHRA OBSTRUCTION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; BLADDER OBSTRUCTION; GENETICS; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT;

ANIMALS; BLOTTING, WESTERN; LYSOPHOSPHOLIPIDS; MALE; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION; SPHINGOSINE; UP-REGULATION; URINARY BLADDER NECK OBSTRUCTION;

EID: 77955061735     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2009.09156.x     Document Type: Article

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