Effect of Age on the Role of Rho-Kinase in Short-term Partial Bladder Outlet Obstruction

Urology

Volumn 71, Issue 3, 2008, Pages 541-545

  Guven, Ahmet ^a,c   Lin, Wei Yu ^b,c,d   Neuman, Paul ^d   Kogan, Barry A ^c   Levin, Robert ^c,d,e   Mannikarottu, Anita ^c,d  

^a GULHANE SCHOOL OF MEDICINE   (Turkey)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^c ALBANY MEDICAL COLLEGE   (United States)

^d ALBANY COLLEGE OF PHARMACY AND HEALTH SCIENCES   (United States)

^e STRATTON VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; RHO KINASE;

ARTICLE; BLADDER NECK STENOSIS; CONTROLLED STUDY; DETRUSOR MUSCLE; DISEASE COURSE; ISOMER; MALE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

AGE FACTORS; ANIMALS; ISOENZYMES; MALE; MUSCLE, SMOOTH; RABBITS; RHO-ASSOCIATED KINASES; TIME FACTORS; URINARY BLADDER; URINARY BLADDER NECK OBSTRUCTION;

EID: 40649129026     PISSN: 00904295     EISSN: 15279995     Source Type: Journal    
DOI: 10.1016/j.urology.2007.11.010     Document Type: Article

References (21)

1. Chatelain C., Denis L., Foo K., et al. Benign Prostatic Hyperplasia (2001), Health Publications Ltd, Paris 535
2. Levin R.M., Haugaard N., O'Connor L., et al. Obstructive response of human bladder to BPH vs. rabbit bladder response to partial outlet obstruction: a direct comparison. Neurourol Urodyn 19 (2000) 609-629
3. Andersson K.E., and Arner A. Urinary bladder contraction and relaxation: physiology and pathophysiology. Physiol Rev 84 (2004) 935-986
4. Levin R.M., Chicester P., Hass M.A., et al. Obstructive bladder dysfunction: morphological, biochemical, and molecular changes. Eur Urol Suppl 1 (2002) 14-20
5. Guven A., Kalorin C., Onal B., et al. Novel biomarkers of bladder decompensation after partial bladder obstruction. Neurourol Urodyn 26 7 (2007) 1036-1042
6. Somlyo A.P., and Somlyo A.V. Signal transduction by G-proteins, rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II. J Physiol 522 (2000) 177-185
7. Takahashi R., Nishimura J., Hirano K., et al. Ca2+ sensitization in contraction of human bladder smooth muscle. J Urol 172 (2004) 748-752
8. Horowitz A., Menice C.B., Laporte R., et al. Mechanisms of smooth muscle contraction. Physiol Rev 76 (1996) 967-1003
9. Amano M., Ito M., Kimura K., et al. Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase). J Biol Chem 271 (1996) 20246-20249
10. Feng J., Ito M., Ichikawa K., et al. Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle myosin phosphatase. J Biol Chem 274 (1999) 37385-37390
11. Bing W., Chang S., Hypolite J.A., et al. Obstruction-induced changes in urinary bladder smooth muscle contractility: a role for Rho kinase. Am J Physiol Renal Physiol 285 (2003) F990-F997
12. Wibberley A., Chen Z., Hu E., et al. Expression and functional role of Rho-kinase in rat urinary bladder smooth muscle. Br J Pharmacol 138 (2003) 757-766
13. Guven A., Onal B., Kalorin V., et al. Long term partial bladder outlet obstruction induced contractile dysfunction in male rabbits: a role for Rho-kinase. Neurourol Urodyn 26 7 (2007) 1043-1049
14. Mannikarottu A.S., Hypolite J.A., Zderic S.A., et al. Regional alterations in the expression of smooth muscle myosin isoforms in response to partial bladder outlet obstruction. J Urol 173 (2005) 302-308
15. Ridley A.J., and Hall A. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70 (1992) 389-399
16. Aikawa R., Komuro I., Yamazaki T., et al. Rho family small G proteins play critical roles in mechanical stress-induced hypertrophic responses in cardiac myocytes. Circ Res 84 (1999) 458-466
17. Uehata M., Ishizaki T., Satoh H., et al. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 389 (1997) 990-994
18. Rajasekaran M., Wilkes N., Kuntz S., et al. Rho-kinase inhibition suppresses bladder hyperactivity in spontaneously hypertensive rats. Neurourol Urodyn 24 (2005) 295-300
19. Sylvester J.T. The tone of pulmonary smooth muscle: ROK and Rho music?. Am J Physiol Lung Cell Mol Physiol 287 (2004) L624-L630
20. Greenland J.E., and Brading A.F. The effect of bladder outflow obstruction on detrusor blood flow changes during the voiding cycle in conscious pigs. J Urol 165 (2001) 245-248
21. Rikitake Y., Kim H.H., Huang Z., et al. Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection. Stroke 36 (2005) 2251-2257