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Volumn 132, Issue 30, 2010, Pages 10278-10285

Isolation, structural elucidation, and absolute stereochemistry of enigmazole a, a cytotoxic phosphomacrolide from the papua new guinea marine sponge cinachyrella enigmatica

Author keywords

[No Author keywords available]

Indexed keywords

ABSOLUTE STEREOCHEMISTRY; ANTI-TUMORS; CELL LINES; CHEMICAL DERIVATIZATION; CHIRAL CENTERS; CYTOTOXIC; MACROLIDES; MARINE SOURCES; MARINE SPONGE; MICRO-SCALES; OXAZOLES; PAPUA NEW GUINEA; STRUCTURAL ELUCIDATION; TETRAHYDROPYRAN;

EID: 77955048478     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja1016766     Document Type: Article
Times cited : (74)

References (81)
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    • Prialt (Elan Pharmaceuticals), also known as ziconotide, is a synthetic form of the cone snail toxin f-conotoxin VIIA
    • Prialt (Elan Pharmaceuticals), also known as ziconotide, is a synthetic form of the cone snail toxin f-conotoxin VIIA.
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    • Yondelis (Zeltia and Johnson & Johnson/OrthoBiotech), also known as trabectedin, ecteinascidin-743, or ET-743, was originally isolated from the ascidian Ecteinascidia turbinata. Wright, A. E., Forleo, D. A., Gunawardana, G. P., Gunasekera, S. P., Koehn, F. E., and McConnell, O. J. J. Org. Chem. 1990, 55, 4508-4512
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    • Molecular Targets Laboratory. Catalog of Compounds, https://ccrod.cancer. gov/confluence/display/CCRMTDPBeu/Introduction+to+MTL.
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    • Cinachyrella enigmatica (Burton, 1934) is the accepted taxonomic classification, but this sponge has also been described in the past as Raphidotethya enigmatica. In;, Eds.; Kluwer Academic/Plenum Publishers: New York
    • Cinachyrella enigmatica (Burton, 1934) is the accepted taxonomic classification, but this sponge has also been described in the past as Raphidotethya enigmatica. Van Soest, R. W. M. and Rützler, K. In Systema Porifera: A Guide to the Classification of Sponges; Hooper, J. N. A. and Van Soest, R. W. M., Eds.; Kluwer Academic/Plenum Publishers: New York, 2002; pp 85-98.
    • (2002) Systema Porifera: A Guide to the Classification of Sponges , pp. 85-98
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    • CP = 5.3 Hz and slight broadening of d 38.7 (C6) were observed
    • CP = 5.3 Hz and slight broadening of d 38.7 (C6) were observed
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    • A recent study has verified that hydrolysis of alkyl phosphate monoesters proceeds by a unimolecular mechanism. See
    • A recent study has verified that hydrolysis of alkyl phosphate monoesters proceeds by a unimolecular mechanism. See: Grzyska, P. K., Czyryca, P. G., Purcell, J., and Hengge, A. C. J. Am. Chem. Soc. 2003, 125, 13106-13111
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    • 1H NMR spectrum and the mass spectrum showed no evidence of deuterium incorporation
    • 1H NMR spectrum and the mass spectrum showed no evidence of deuterium incorporation


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.