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Love, G. D.; Grosjean, E.; Stalvies, C.; Fike, D. A.; Grotzinger, J. P.; Bradley, A. S.; Kelly, A. E.; Bhatia, M.; Meredith, W.; Snape, C. E.; Bowring, S. A.; Condon, D. J.; Summons, R. E. Nature 2009, 457, 718.
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0029034588
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For example, the bacterial population in Xestospongia testudinaria accounts for >50% of cells
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For example, the bacterial population in Xestospongia testudinaria accounts for >50% of cells: (a) Brantley, S. E.; Molinski, T. F.; Preston, C. M.; Delong, E. F. Tetrahedron 1995, 51, 7667.
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0029854666
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(b) Searle, P. A.; Molinski, T. F.; Brzezinski, L. J.; Leahy, J. W. J. Am. Chem. Soc. 1996, 118, 9422.
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(a) MacMillan, J. B.; Xiong-Zhou, G.; Skepper, C. K.; Molinski, T. F. J. Org. Chem. 2008, 73, 3699.
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Molinski, T.F.4
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34247112862
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13
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0011205674
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A typical value for similar hexahydro-1H-isoindolone geminal couplings is J = -9 Hz
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A typical value for similar hexahydro-1H-isoindolone geminal couplings is J = -9 Hz.(a) Back, T. G.; Brunner, K.; Codding, P. W.; Roszak, A. W. Heterocycles 1989, 28, 219.
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0003289262
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(b) Jeffs, P. W.; Molina, G.; Cortese, N. A.; Hauck, P. R.; Wolfram, J. J. Org. Chem. 1982, 47, 3876.
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15
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0028200031
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3-Methyl-3-ethylazetidinone is J = -5.4 Hz
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3-Methyl-3-ethylazetidinone is J = -5.4 Hz:(c) Cativiela, C.; Diaz-de-Villegas, M. D.; Galvez, J. A. J. Org. Chem. 1994, 59, 2497.
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17
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67650549651
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note
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H17-C15) 2.5 Hz (HETLOC) - require the C14 methyl group be extended exo to the macrocycle and relays the configuration C5 to C14 and C17.
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-
-
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18
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67650528729
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note
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Molecular mechanics (MMFF94, Spartan 04) and constraints from NOE and J data. The C2-C3 and C12-C13 double bonds were both E (NOE).
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20
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18744394940
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Masuno, M. N.; Young, D. M.; Hoepker, A. C.; Skepper, C. K.; Molinski, T. F. J. Org. Chem. 2005, 70, 4162.
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Molinski, T.F.5
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21
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0035793253
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(a) Paterson, I.; Davies, R. D. M.; Marquez, R. Angew. Chem., Int. Ed. 2001, 40, 603.
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23
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0034649726
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(c) Olivo, H. F.; Velazquez, F.; Trevisan, H. C. Org. Lett. 2000, 2, 4055.
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Olivo, H.F.1
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Trevisan, H.C.3
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25
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67650519018
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note
-
1H NMR and CD.
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-
-
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26
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67650555345
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note
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R = 13.84, 11.19, 9.05, and 9.90 min, respectively.
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-
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27
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67650528730
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note
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50 96.5 μg/mL) and antifungal activity against Cryptococcus neoformans (MIC 16 μ g/mL).
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28
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67650510611
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One report describes 1,1,1,7,7,7-hexachloro-2,6-dihydroxyheptan-4- one - formally, the double aldol addition product of acetone and chloral - from the Mongolian plant Oxytropis glabra
-
One report describes 1,1,1,7,7,7-hexachloro-2,6-dihydroxyheptan-4- one - formally, the double aldol addition product of acetone and chloral - from the Mongolian plant Oxytropis glabra: Yu, R.; Li, X.; Zhu, T.; Yang, G.; Li, Z.; Yang, B. Shenyang Yaoxueyuan Xuebao 1991, 8, 113.
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Yu, R.1
Li, X.2
Zhu, T.3
Yang, G.4
Li, Z.5
Yang, B.6
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29
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0001025484
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Unrelated 4,4,4-trichloroleucine peptides have been known from the sponge Dysidea herbacea since 1977
-
Unrelated 4,4,4-trichloroleucine peptides have been known from the sponge Dysidea herbacea since 1977: Kazlauskas, R.; Lidgard, R. O.; Wells, R. J.; Vetter, W. Tetrahedron Lett. 1977, 18, 3183.
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Tetrahedron Lett.
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Kazlauskas, R.1
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Wells, R.J.3
Vetter, W.4
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0030830667
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(a) Klein, D.; Braekman, J. C.; Daloze, D.; Hoffmann, L.; Demoulin, V. J. Nat. Prod. 1997, 60, 1057.
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Klein, D.1
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(b) Luesch, H.; Yoshida, W. Y.; Harrigan, G. G.; Doom, J. P.; Moore, R. E.; Paul, V. J. J. Nat. Prod. 2002, 65, 1945.
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Luesch, H.1
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Paul, V.J.6
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