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Volumn 131, Issue 22, 2009, Pages 7552-7553

A tetrachloro polyketide hexahydro-1H-isoindolone, muironolide A, from the marine sponge Phorbas sp. natural products at the nanomole scale

Author keywords

[No Author keywords available]

Indexed keywords

ABSOLUTE CONFIGURATION; CYANOBACTERIUM; MACROLIDE; MARINE SPONGE; MICRO-PROBE; NATURAL PRODUCTS; NEW CHEMICAL ENTITIES; NMR DATA; PHORBOXAZOLES; POLYKETIDE; REFORMATSKY REACTION;

EID: 67650523186     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9024929     Document Type: Article
Times cited : (62)

References (33)
  • 2
    • 0029034588 scopus 로고
    • For example, the bacterial population in Xestospongia testudinaria accounts for >50% of cells
    • For example, the bacterial population in Xestospongia testudinaria accounts for >50% of cells: (a) Brantley, S. E.; Molinski, T. F.; Preston, C. M.; Delong, E. F. Tetrahedron 1995, 51, 7667.
    • (1995) Tetrahedron , vol.51 , pp. 7667
    • Brantley, S.E.1    Molinski, T.F.2    Preston, C.M.3    Delong, E.F.4
  • 13
    • 0011205674 scopus 로고
    • A typical value for similar hexahydro-1H-isoindolone geminal couplings is J = -9 Hz
    • A typical value for similar hexahydro-1H-isoindolone geminal couplings is J = -9 Hz.(a) Back, T. G.; Brunner, K.; Codding, P. W.; Roszak, A. W. Heterocycles 1989, 28, 219.
    • (1989) Heterocycles , vol.28 , pp. 219
    • Back, T.G.1    Brunner, K.2    Codding, P.W.3    Roszak, A.W.4
  • 17
    • 67650549651 scopus 로고    scopus 로고
    • note
    • H17-C15) 2.5 Hz (HETLOC) - require the C14 methyl group be extended exo to the macrocycle and relays the configuration C5 to C14 and C17.
  • 18
    • 67650528729 scopus 로고    scopus 로고
    • note
    • Molecular mechanics (MMFF94, Spartan 04) and constraints from NOE and J data. The C2-C3 and C12-C13 double bonds were both E (NOE).
  • 25
    • 67650519018 scopus 로고    scopus 로고
    • note
    • 1H NMR and CD.
  • 26
    • 67650555345 scopus 로고    scopus 로고
    • note
    • R = 13.84, 11.19, 9.05, and 9.90 min, respectively.
  • 27
    • 67650528730 scopus 로고    scopus 로고
    • note
    • 50 96.5 μg/mL) and antifungal activity against Cryptococcus neoformans (MIC 16 μ g/mL).
  • 28
    • 67650510611 scopus 로고
    • One report describes 1,1,1,7,7,7-hexachloro-2,6-dihydroxyheptan-4- one - formally, the double aldol addition product of acetone and chloral - from the Mongolian plant Oxytropis glabra
    • One report describes 1,1,1,7,7,7-hexachloro-2,6-dihydroxyheptan-4- one - formally, the double aldol addition product of acetone and chloral - from the Mongolian plant Oxytropis glabra: Yu, R.; Li, X.; Zhu, T.; Yang, G.; Li, Z.; Yang, B. Shenyang Yaoxueyuan Xuebao 1991, 8, 113.
    • (1991) Shenyang Yaoxueyuan Xuebao , vol.8 , pp. 113
    • Yu, R.1    Li, X.2    Zhu, T.3    Yang, G.4    Li, Z.5    Yang, B.6
  • 29
    • 0001025484 scopus 로고    scopus 로고
    • Unrelated 4,4,4-trichloroleucine peptides have been known from the sponge Dysidea herbacea since 1977
    • Unrelated 4,4,4-trichloroleucine peptides have been known from the sponge Dysidea herbacea since 1977: Kazlauskas, R.; Lidgard, R. O.; Wells, R. J.; Vetter, W. Tetrahedron Lett. 1977, 18, 3183.
    • Tetrahedron Lett. , vol.1977 , Issue.18 , pp. 3183
    • Kazlauskas, R.1    Lidgard, R.O.2    Wells, R.J.3    Vetter, W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.