Crystal structure of the nosiheptide-resistance methyltransferase of streptomyces actuosus

Biochemistry

Volumn 49, Issue 30, 2010, Pages 6440-6450

  Yang, Huirong ^a,b,c   Wang, Zhe ^b   Shen, Yan ^b   Wang, Ping ^b,c   Jia, Xu ^b   Zhao, Liang ^b   Zhou, Pei ^b   Gong, Rui ^b,c   Li, Ze ^b,c   Yang, Ying ^b,c   Chen, Dongrong ^b   Murchie, Alastair I H ^b   Xu, Yanhui ^a,b,c  

^a FUDAN UNIVERSITY SHANGHAI CANCER CENTER   (China)

^b FUDAN UNIVERSITY   (China)

^c FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL ANALYSIS; CATALYTIC DOMAINS; CATALYTIC MECHANISMS; CRITICAL REGION; HOMODIMERS; METHYL GROUP; METHYLTRANSFERASE ACTIVITY; METHYLTRANSFERASES; N-TERMINALS; PEPTIDE ANTIBIOTICS; RNA BINDING DOMAINS; RNA RECOGNITION; RNA SUBSTRATE; S ADENOSYL L METHIONINES; STRUCTURAL MODELS; STRUCTURAL STUDIES; SUBSTRATE RECOGNITION;

ANTIBIOTICS; ESCHERICHIA COLI; HYDROCARBONS; MODEL STRUCTURES; PEPTIDES; RNA; SULFUR;

CRYSTAL STRUCTURE;

HOMODIMER; METHYLTRANSFERASE; NOSIHEPTIDE; NOSIHEPTIDE RESISTANCE METHYLTRANSFERASE; RNA 23S; RNA METHYLTRANSFERASE; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANTIBIOTIC RESISTANCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME ACTIVITY; ENZYME MODIFICATION; ENZYME SUBSTRATE; MOLECULAR RECOGNITION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RNA ANALYSIS; RNA BINDING; STREPTOMYCES; STREPTOMYCES ACTUOSUS;

BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; DRUG RESISTANCE, BACTERIAL; METHYLATION; METHYLTRANSFERASES; PROTEIN MULTIMERIZATION; RNA; STREPTOMYCES; SUBSTRATE SPECIFICITY; THIAZOLES;

ESCHERICHIA COLI; STREPTOMYCES ACTUOSUS;

EID: 77955026872     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi1005915     Document Type: Article

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