Structure of the thiostrepton resistance methyltransferase-S-adenosyl-L-methionine complex and its interaction with ribosomal RNA

Journal of Biological Chemistry

Volumn 284, Issue 25, 2009, Pages 17013-17020

  Dunstan, Mark S ^a   Hang, Pei C ^b   Zelinskaya, Natalia V ^c   Honek, John F ^b   Conn, Graeme L ^a,c  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF WATERLOO   (Canada)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING DOMAIN; BIOLOGICAL UNITS; ELECTROSTATIC SURFACES; HOMODIMER; IN-VITRO; IN-VITRO ANALYSIS; INTERNAL LOOPS; METHYLTRANSFERASE; MOLECULAR DOCKING; N-TERMINAL; N-TERMINAL DOMAINS; RIBOSOMAL RNA; RIBOSOMAL RNA (RRNA); RNA BINDING; S ADENOSYL L METHIONINES; STRUCTURAL ELEMENTS; TARGET DOMAIN; TARGET RECOGNITION; TARGET SITES; THIOSTREPTON; X RAY CRYSTAL STRUCTURES;

ALKYLATION; AMINES; AMINO ACIDS; ENZYMES; METHYLATION; NUCLEIC ACIDS; NUCLEOTIDES; ORGANIC ACIDS; RNA; TARGETS;

CRYSTAL STRUCTURE;

ADENINE; METHYLTRANSFERASE; NUCLEOTIDE; PHENYLALANINE; RIBOSOME RNA; S ADENOSYLMETHIONINE; THIOSTREPTON RESISTANCE RNA METHYLTRANSFERASE; UNCLASSIFIED DRUG; URACIL;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME STRUCTURE; IN VITRO STUDY; METHYLATION; MOLECULAR DOCKING; MOLECULAR RECOGNITION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN RNA BINDING; X RAY;

BASE SEQUENCE; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; DRUG RESISTANCE, BACTERIAL; MACROMOLECULAR SUBSTANCES; METHYLTRANSFERASES; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; RNA, BACTERIAL; RNA, RIBOSOMAL, 23S; S-ADENOSYLMETHIONINE; STAPHYLOCOCCUS AUREUS; STATIC ELECTRICITY; THIOSTREPTON;

EID: 67650544978     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M901618200     Document Type: Article

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