Insights into catalysis by a knotted TrmD tRNA methyltransferase

Journal of Molecular Biology

Volumn 333, Issue 5, 2003, Pages 931-949

  Elkins, Patricia A ^a   Watts, Joseph M ^b   Zalacain, Magdalena ^a   Van Thiel, Adam ^b,f   Vitazka, Patrik R ^b,c   Redlak, Maria ^b,c   Andraos Selim, Cecile ^d   Rastinejad, Fraydoon ^e   Holmes, Walter M ^b  

^a GLAXOSMITHKLINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^d HAMPTON UNIVERSITY   (United States)

^e UNIVERSITY OF VIRGINIA   (United States)

^f UNIVERSITY OF THE WEST OF ENGLAND   (United Kingdom)

Author keywords

Crystal structure; Knot; Methylation; Mutagenesis; tRNA

Indexed keywords

ADENINE; BACTERIAL ENZYME; DIMER; METHIONINE; MONOMER; PEPTIDE; S ADENOSYLHOMOCYSTEINE; THROMBOSPONDIN; TRANSFER RNA METHYLTRANSFERASE;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME DEGRADATION; ESCHERICHIA COLI; HYDROPHOBICITY; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE BINDING SITE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN METHYLATION; PROTEIN RNA BINDING;

ESCHERICHIA COLI; HOMO; LOTUS;

EID: 0142216637     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2003.09.011     Document Type: Article

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