Differential impact of milk fatty acid profiles on cardiovascular risk biomarkers in healthy men and women

European Journal of Clinical Nutrition

Volumn 64, Issue 7, 2010, Pages 752-759

  Malpuech Brugere C ^a,b,c   Mouriot, J ^a,b,c,d   Boue Vaysse, C ^e   Combe, N ^e   Peyraud, J L ^f   Leruyet, P ^g   Chesneau, G ^d   Morio, B ^a,b,c   Chardigny, J M ^a,b,c  

^a INRA and University of Auvergne   (France)

^b UNIVERSITÉ CLERMONT AUVERGNE   (France)

^c CRNH AUVERGNE   (France)

^d Département de Nutrition ^*  (France)

^e Institut des Corps Gras   (France)

^f CEMAGREF   (France)

^g Lactalis Research and Development   (France)

Author keywords

cardiovascular risk factors; cholesterol; human nutrition; lipids; milk fat; trans fatty acids

Indexed keywords

APOLIPOPROTEIN B; BIOLOGICAL MARKER; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MILK FAT; MONOUNSATURATED FATTY ACID; POLYUNSATURATED FATTY ACID; SATURATED FATTY ACID; TRANS FATTY ACID;

ADULT; ARTICLE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DAIRY PRODUCT; DOUBLE BLIND PROCEDURE; FAT CONTENT; FAT INTAKE; FATTY ACID ANALYSIS; FEMALE; FOOD ANALYSIS; FOOD COMPOSITION; FOOD INTAKE; HUMAN; HUMAN EXPERIMENT; INTERVENTION STUDY; LIPID COMPOSITION; MALE; NORMAL HUMAN; PARALLEL DESIGN; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE;

ADOLESCENT; ADULT; ANIMALS; BIOLOGICAL MARKERS; CARDIOVASCULAR DISEASES; CATTLE; CHOLESTEROL; DAIRY PRODUCTS; DIETARY FATS; DOUBLE-BLIND METHOD; FATTY ACIDS; FEMALE; HUMANS; LIPIDS; MALE; MIDDLE AGED; MILK; RISK FACTORS; TRANS FATTY ACIDS; YOUNG ADULT;

EID: 77955013814     PISSN: 09543007     EISSN: 14765640     Source Type: Journal    
DOI: 10.1038/ejcn.2010.73     Document Type: Article

References (30)

1. Afssa (2005). Risques et benefices pour la sante des acides gras trans apportes par les aliments-Health risks and benefits of trans fatty acids in food-Recommendations (synthesis), pp. 1-217. AFSSA, Maison-Alfort.
2. Ascherio A, Katan MB, Zock PL, Stampfer MJ, Willett WC (1999). Trans fatty acids and coronary heart disease. N Engl J Med 340, 1994-1998.
3. Baylin A, Kabagambe EK, Ascherio A, Spiegelman D, Campos H (2003). High 18:2 trans-fatty acids in adipose tissue are associated with increased risk of nonfatal acute myocardial infarction in Costa Rican adults. J Nutr 133, 1186-1191.
4. Booker CS, Mann JI (2008). Trans fatty acids and cardiovascular health: translation of the evidence base. Nutr Metab Cardiovasc Dis 18, 448-456.
5. Chardigny JM, Destaillats F, Malpuech-Brugere C, Moulin J, Bauman DE, Lock AL et al. (2008). Do trans fatty acids from industrially produced sources and from natural sources have the same effect on cardiovascular disease risk factors in healthy subjects? Results of the trans Fatty Acids Collaboration (TRANSFACT) study. Am J Clin Nutr 87, 558-566.
6. Chardigny JM, Malpuech-Brugere C, Dionisi F, Bauman DE, German B, Mensink RP et al. (2006). Rationale and design of the TRANSFACT project phase I: a study to assess the effect of the two different dietary sources of trans fatty acids on cardiovascular risk factors in humans. Contemp Clin Trials 27, 364-373.
7. Chilliard Y, Ferlay A (2004). Dietary lipids and forages interactions on cow and goat milk fatty acid composition and sensory properties. Reprod Nutr Dev 44, 467-492.
8. Dalainas I, Ioannou HP (2008). The role of trans fatty acids in atherosclerosis, cardiovascular disease and infant development. IntAngiol 27, 146-156.
9. European Heart Network (2008). European cardiovascular disease statistics. In: Allender S, Scarborough P, Peto V, Rayner M, Leal J, Luengo-Fernandez R et al. (eds), 2008 edn. European Heart Network: Brussels. pp 7-8.
10. Gebauer SK, Psota TL, Harris WS, Kris-Etherton PM (2006). n-3 fatty acid dietary recommendations and food sources to achieve essentiality and cardiovascular benefits. Am J Clin Nutr 83, 1526S-1535S.
11. Gebauer SK, Psota TL, Kris-Etherton PM (2007). The diversity of health effects of individual trans fatty acid isomers. Lipids 42, 787-799.
12. Hu FB, Stampfer MJ, MansonJE, Rimm E, Colditz GA, Rosner BA et al. (1997). Dietary fat intake and the risk of coronary heart disease in women. N Engl J Med 337, 1491-1499.
13. Jakobsen MU, Overvad K, Dyerberg J, Heitmann BL (2008). Intake of ruminant trans fatty acids and risk of coronary heart disease. Int J Epidemiol 37, 173-182.
14. Katan MB, Zock PL, Mensink RP (1995). Trans fatty acids and their effects on lipoproteins in humans. Annu Rev Nutr 15, 473-493.
15. Mansour MP, Li D, Sinclair AJ (2001). The occurrence of trans-18:1 isomers in plasma lipids classes in humans. Eur J Clin Nutr 55, 59-64.
16. Mensink RP, Zock PL, Kester AD, Katan MB (2003). Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta- analysis of 60 controlled trials. Am J Clin Nutr 77, 1146-1155.
17. Motard-Belanger A, Charest A, Grenier G, Paquin P, Chouinard Y, Lemieux S et al. (2008). Study of the effect of trans fatty acids from ruminants on blood lipids and other risk factors for cardiovascular disease. Am J Clin Nutr 87, 593-599.
18. Mozaffarian D, Clarke R (2009). Quantitative effects on cardiovascular risk factors and coronary heart disease risk of replacing partially hydrogenated vegetable oils with other fats and oils. Eur J Clin Nutr 63 (Suppl 2), S22-S33.
19. Poppitt SD, Keogh GF, Mulvey TB, McArdle BH, MacGibbon AK, Cooper GJ (2002). Lipid-lowering effects of a modified butter-fat: a controlled intervention trial in healthy men. Eur J Clin Nutr 56, 64-71.
20. Rivellese AA, Maffettone A, Vessby B, Uusitupa M, Hermansen K, Berglund L et al. (2003). Effects of dietary saturated, monounsa- turated and n-3 fatty acids on fasting lipoproteins, LDL size and post-prandial lipid metabolism in healthy subjects. Atherosclerosis 167, 149-158.
21. Roy A, Ferlay A, Chilliard Y (2006). Production of butter fat rich in trans10-C18:1 for use in biomedical studies in rodents. Reprod Nutr Dev 46, 211-218.
22. Scientific Panel on Dietetic Products NaA (2004). Opinion of the Scientific Panel on Dietetic Products, Nutrition and Allergies on a request from the Commission related to the presence of trans fatty acids in foods and the effect on human health of the consumption of trans fatty acids (Request No EFSA-Q-2003-022). EFSA J 81, 1-49.
23. Seidel C, Deufel T, Jahreis G (2005). Effects of fat-modified dairy products on blood lipids in humans in comparison with other fats. Ann Nutr Metab 49, 42-48.
24. Stampfer MJ, Sacks FM, Salvini S, Willett WC, Hennekens CH (1991). A prospective study of cholesterol, apolipoproteins, and the risk of myocardial infarction. N Engl J Med 325, 373-381.
25. Stender S, Dyerberg J (2003). The influence of trans fatty acids on health. 4th edn. A Report from the Danish Nutrition Council Publication. Danish Nutrition Council: Copenhagen, Denmark. Publication No. 34.
26. Stender S, Dyerberg J (2004). Influence of trans fatty acids on health. Ann Nutr Metab 48, 61-66.
27. Tholstrup T, Raff M, Basu S, Nonboe P, Sejrsen K, Straarup EM (2006). Effects of butter high in ruminant trans and monounsaturated fatty acids on lipoproteins, incorporation of fatty acids into lipid classes, plasma C-reactive protein, oxidative stress, hemostatic variables, and insulin in healthy young men. Am J Clin Nutr 83, 237-243.
28. Tricon S, Burdge GC, Jones EL, Russell JJ, El-Khazen S, Moretti E et al. (2006). Effects of dairy products naturally enriched with cis-9,trans-11 conjugated linoleic acid on the blood lipid profile in healthy middle-aged men. Am J Clin Nutr 83, 744-753.
29. Vermunt SH, Beaufrere B, Riemersma RA, Sebedio JL, Chardigny JM, Mensink RP (2001). Dietary trans alpha-linolenic acid from deodorised rapeseed oil and plasma lipids and lipoproteins in healthy men: the TransLinE Study. Br J Nutr 85, 387-392.
30. Yu S, Derr J, Etherton TD, Kris-Etherton PM (1995). Plasma cholesterol-predictive equations demonstrate that stearic acid is neutral and monounsaturated fatty acids are hypocholesterol- emic. Am J Clin Nutr 61, 1129-1139.