메뉴 건너뛰기




Volumn 2, Issue 4, 2010, Pages 461-465

Reslizumab for pediatric eosinophilic esophagitis

Author keywords

Cinquil ; eosinophils; IL 5; pediatric eosinophilic esophagitis; reslizumab

Indexed keywords

ALLERGEN; CHEMOKINE RECEPTOR CCR3; CINQUIL; CORTICOSTEROID; CYTOKINE; EOTAXIN; EOTAXIN 3; EP 00763592; EP 00765392; INTERLEUKIN 5; OVALBUMIN; RESLIZUMAB; UNCLASSIFIED DRUG; US 06316227; US 06734286; WO 09201472; WO 09535375;

EID: 77955003518     PISSN: 1750743X     EISSN: None     Source Type: Journal    
DOI: 10.2217/imt.10.41     Document Type: Review
Times cited : (5)

References (37)
  • 1
    • 36448979869 scopus 로고    scopus 로고
    • Eosinophilic esophagitis: Association with allergic disorders
    • Assaad A: Eosinophilic esophagitis: association with allergic disorders. Gastrointest. Endosc. Clin. N. Am. 18, 119-132 (2008).
    • (2008) Gastrointest. Endosc. Clin. N. Am. , vol.18 , pp. 119-132
    • Assaad, A.1
  • 2
    • 42749087173 scopus 로고    scopus 로고
    • Atopic characteristics of adult patients with eosinophilic esophagitis
    • Roy-Ghanta S, Larosa DF, Katzka DA: Atopic characteristics of adult patients with eosinophilic esophagitis. Clin. Gastroenterol. Hepatol. 6, 531-535 (2008).
    • (2008) Clin. Gastroenterol. Hepatol. , vol.6 , pp. 531-535
    • Roy-Ghanta, S.1    Larosa, D.F.2    Katzka, D.A.3
  • 3
    • 34047223408 scopus 로고    scopus 로고
    • Polysensitization to aeroallergens and food in eosinophilic esophagitis in a pediatric population
    • Plaza-Martin AM, Jimenez-Feijoo R, Andaluz C et al.: Polysensitization to aeroallergens and food in eosinophilic esophagitis in a pediatric population. Allergolog. Immunopathol. 35, 35-37 (2007).
    • (2007) Allergolog. Immunopathol. , vol.35 , pp. 35-37
    • Plaza-Martin, A.M.1    Jimenez-Feijoo, R.2    Andaluz, C.3
  • 4
    • 35148820622 scopus 로고    scopus 로고
    • Dichotomy of food and inhalant allergen sensitization in eosinophilic esophagitis
    • Sugnanam KK, Collins JT, Smith PK et al.: Dichotomy of food and inhalant allergen sensitization in eosinophilic esophagitis. Allergy 62, 1257-1260 (2007).
    • (2007) Allergy , vol.62 , pp. 1257-1260
    • Sugnanam, K.K.1    Collins, J.T.2    Smith, P.K.3
  • 5
    • 41949132491 scopus 로고    scopus 로고
    • Eosinophilic esophagitis: Management and pharmacotherapy
    • De Angelis P, Morino G, Pane A et al.: Eosinophilic esophagitis: management and pharmacotherapy. Exp. Opin. Pharmacother. 9, 731-740 (2008).
    • (2008) Exp. Opin. Pharmacother. , vol.9 , pp. 731-740
    • De Angelis, P.1    Morino, G.2    Pane, A.3
  • 6
    • 32444443951 scopus 로고    scopus 로고
    • Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis
    • Blanchard C, Wang N, Stringer KF et al.: Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis. J. Clin. Invest. 116, 536-547 (2006).
    • (2006) J. Clin. Invest. , vol.116 , pp. 536-547
    • Blanchard, C.1    Wang, N.2    Stringer, K.F.3
  • 7
    • 0035218441 scopus 로고    scopus 로고
    • Idiopathic eosinophilic esophagitis is associated with a T(H)2-type allergic inflammatory response
    • Straumann A, Bauer M, Fischer B, Blaser K, Simon HU: Idiopathic eosinophilic esophagitis is associated with a T(H)2-type allergic inflammatory response. J. Allergy Clin. Immunol. 108, 954-961 (2001).
    • (2001) J. Allergy Clin. Immunol. , vol.108 , pp. 954-961
    • Straumann, A.1    Bauer, M.2    Fischer, B.3    Blaser, K.4    Simon, H.U.5
  • 8
    • 0242406890 scopus 로고    scopus 로고
    • Intratracheal IL-13 induces eosinophilic esophagitis by an IL-5, eotaxin-1, and STAT6-dependent mechanism
    • Mishra A, Rothenberg ME: Intratracheal IL-13 induces eosinophilic esophagitis by an IL-5, eotaxin-1, and STAT6-dependent mechanism. Gastroenterology 125, 1419-1427 (2003).
    • (2003) Gastroenterology , vol.125 , pp. 1419-1427
    • Mishra, A.1    Rothenberg, M.E.2
  • 9
    • 0035174173 scopus 로고    scopus 로고
    • An etiological role for aeroallergens and eosinophils in experimental esophagitis
    • Mishra A, Hogan SP, Brandt EB, Rothenberg ME: An etiological role for aeroallergens and eosinophils in experimental esophagitis. J. Clin. Invest. 107, 83-90 (2001).
    • (2001) J. Clin. Invest. , vol.107 , pp. 83-90
    • Mishra, A.1    Hogan, S.P.2    Brandt, E.B.3    Rothenberg, M.E.4
  • 11
    • 55349135527 scopus 로고    scopus 로고
    • Eosinophilic gastroenteritis
    • Oh HE, Chetty R: Eosinophilic gastroenteritis. J. Gastroenterol. 43, 741-750 (2008).
    • (2008) J. Gastroenterol. , vol.43 , pp. 741-750
    • Oh, H.E.1    Chetty, R.2
  • 12
    • 36448972235 scopus 로고    scopus 로고
    • Pharmacologic treatment of eosinophilic esophagitis
    • Liacouras CA: Pharmacologic treatment of eosinophilic esophagitis. Gastrointest. Endosc. Clin. N. Am. 18, 169-178 (2008).
    • (2008) Gastrointest. Endosc. Clin. N. Am. , vol.18 , pp. 169-178
    • Liacouras, C.A.1
  • 13
    • 0032694450 scopus 로고    scopus 로고
    • Advances in the immunobiology of eosinophils and their role in disease
    • Walsh GM: Advances in the immunobiology of eosinophils and their role in disease. Crit. Rev. Clin. Lab. Sci. 36 5 453-496 (1999).
    • (1999) Crit. Rev. Clin. Lab. Sci. , vol.36 , Issue.5 , pp. 453-496
    • Walsh, G.M.1
  • 15
    • 0030028768 scopus 로고    scopus 로고
    • Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model
    • Foster PS, Hogan SP, Ramsay AJ, Matthaei KI, Young IG: Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model. J. Exp. Med. 183, 195-201 (1996).
    • (1996) J. Exp. Med. , vol.183 , pp. 195-201
    • Foster, P.S.1    Hogan, S.P.2    Ramsay, A.J.3    Matthaei, K.I.4    Young, I.G.5
  • 16
    • 0029081157 scopus 로고
    • Evaluation of airway hyperreactivity in interleukin-5 transgenic mice
    • Iwamoto T, Takatsu K: Evaluation of airway hyperreactivity in interleukin-5 transgenic mice. Int. Arch. Allergy Immunol. 1(Suppl.), 28-30 (1995).
    • (1995) Int. Arch. Allergy Immunol. , vol.1 , Issue.SUPPL. , pp. 28-30
    • Iwamoto, T.1    Takatsu, K.2
  • 17
    • 4944235680 scopus 로고    scopus 로고
    • Anti-interleukin-5 therapy for asthma and hypereosinophilic syndrome
    • Kay AB, Klion AD: Anti-interleukin-5 therapy for asthma and hypereosinophilic syndrome. Immunol. Allergy Clin. North Am. 24, 645-666 (2004).
    • (2004) Immunol. Allergy Clin. North Am. , vol.24 , pp. 645-666
    • Kay, A.B.1    Klion, A.D.2
  • 18
    • 34347342792 scopus 로고    scopus 로고
    • Interplay of adaptative Th2 immunity with eotaxin-3 C-C chemokine receptor 3 in eosinophilic esophagitis
    • Bullock JZ, Villanueva JM, Blanchard C et al.: Interplay of adaptative Th2 immunity with eotaxin-3 C-C chemokine receptor 3 in eosinophilic esophagitis. J. Pediatr. Gastroenterol. Nutr. 45, 22-31 (2007).
    • (2007) J. Pediatr. Gastroenterol. Nutr. , vol.45 , pp. 22-31
    • Bullock, J.Z.1    Villanueva, J.M.2    Blanchard, C.3
  • 19
    • 32444443951 scopus 로고    scopus 로고
    • Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis
    • Blanchard C, Wang N, Stringer KF et al.: Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis. J. Clin. Invest. 116, 536-547 (2006).
    • (2006) J. Clin. Invest. , vol.116 , pp. 536-547
    • Blanchard, C.1    Wang, N.2    Stringer, K.F.3
  • 20
    • 0036884942 scopus 로고    scopus 로고
    • Decreased expression of membrane IL-5 receptor alpha on human eosinophils: I. Loss of membrane IL-5 receptor alpha on airway eosinophils and increased soluble IL-5 receptor a in the airway after allergen challenge
    • Liu LY, Sedgwick JB, Bates ME et al.: Decreased expression of membrane IL-5 receptor alpha on human eosinophils: I. Loss of membrane IL-5 receptor alpha on airway eosinophils and increased soluble IL-5 receptor a in the airway after allergen challenge. J. Immunol. 169, 6452-6458 (2002).
    • (2002) J. Immunol. , vol.169 , pp. 6452-6458
    • Liu, L.Y.1    Sedgwick, J.B.2    Bates, M.E.3
  • 21
    • 0036884097 scopus 로고    scopus 로고
    • Decreased expression of membrane IL-5 receptor alpha on human eosinophils: II. IL-5 down-modulates its receptor via a proteinase-mediated process
    • Liu LY, Sedgwick JB, Bates ME et al.: Decreased expression of membrane IL-5 receptor alpha on human eosinophils: II. IL-5 down-modulates its receptor via a proteinase-mediated process. J. Immunol. 169, 6459-6466 (2002).
    • (2002) J. Immunol. , vol.169 , pp. 6459-6466
    • Liu, L.Y.1    Sedgwick, J.B.2    Bates, M.E.3
  • 22
    • 0037514567 scopus 로고    scopus 로고
    • Enhanced soluble interleukin-5 receptor alpha expression in nasal polyposis
    • Gevaert P, Bachert C, Holtappels G et al.: Enhanced soluble interleukin-5 receptor alpha expression in nasal polyposis. J. Allergy 58, 371-379 (2003).
    • (2003) J. Allergy , vol.58 , pp. 371-379
    • Gevaert, P.1    Bachert, C.2    Holtappels, G.3
  • 23
    • 0001269056 scopus 로고    scopus 로고
    • Effect of Sch 55700, a humanized monoclonal antibody to human interleukin-5, on eosinophilic responses and bronchial hyperreactivity
    • Egan RW, Athwal D, Bodmer MW et al.: Effect of Sch 55700, a humanized monoclonal antibody to human interleukin-5, on eosinophilic responses and bronchial hyperreactivity. Arzneimittelforschung 49(9), 779-790 (1999).
    • (1999) Arzneimittelforschung , vol.49 , Issue.9 , pp. 779-790
    • Egan, R.W.1    Athwal, D.2    Bodmer, M.W.3
  • 24
    • 0029010479 scopus 로고
    • Inhibition of pulmonary eosinophilia and hyperreactivity by antibodies to interleukin-5
    • Egan RW, Athwahl D, Chou C-C et al.: Inhibition of pulmonary eosinophilia and hyperreactivity by antibodies to interleukin-5. Int. Arch. Allergy Immunol. 107, 321-322 (1995).
    • (1995) Int. Arch. Allergy Immunol. , vol.107 , pp. 321-322
    • Egan, R.W.1    Athwahl, D.2    Chou, C.-C.3
  • 25
    • 8944227052 scopus 로고    scopus 로고
    • Structure and humanization of a rat monoclonal Fab to human interleukin-5
    • Cook WJ, Walter LJ, Murgolo NJ et al.: Structure and humanization of a rat monoclonal Fab to human interleukin-5. Protein Eng. 9, 623-628 (1996).
    • (1996) Protein Eng. , vol.9 , pp. 623-628
    • Cook, W.J.1    Walter, L.J.2    Murgolo, N.J.3
  • 26
    • 71949107298 scopus 로고    scopus 로고
    • Mepolizumab and eosinophil-mediated disease
    • Walsh GM: Mepolizumab and eosinophil-mediated disease. Curr. Med. Chem. 16, 4774-4778 (2009).
    • (2009) Curr. Med. Chem. , vol.16 , pp. 4774-4778
    • Walsh, G.M.1
  • 27
    • 0038643527 scopus 로고    scopus 로고
    • Effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma: A pilot study
    • Kips JC, OConnor BJ, Langley SJ et al.: Effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma: a pilot study. Am. J. Resp. Crit. Care Med. 167, 1655-1659 (2003).
    • (2003) Am. J. Resp. Crit. Care Med. , vol.167 , pp. 1655-1659
    • Kips, J.C.1    Oconnor, B.J.2    Langley, S.J.3
  • 28
    • 67650245693 scopus 로고    scopus 로고
    • Reslizumab, a humanized anti-IL-5 mAb for the treatment of eosinophil-mediated inflammatory conditions
    • Walsh GM: Reslizumab, a humanized anti-IL-5 mAb for the treatment of eosinophil-mediated inflammatory conditions. Curr. Opin. Mol. Ther. 11(3), 329-336 (2009).
    • (2009) Curr. Opin. Mol. Ther. , vol.11 , Issue.3 , pp. 329-336
    • Walsh, G.M.1
  • 30
    • 73449140151 scopus 로고    scopus 로고
    • Anti-interleukin-5 antibody treatment (mepolizumab) in active eosinophilic oesophagitis: A randomised, placebo-controlled, double-blind trial
    • Straumann A, Conus S, Grzonka P et al.: Anti-interleukin-5 antibody treatment (mepolizumab) in active eosinophilic oesophagitis: a randomised, placebo-controlled, double-blind trial. Gut 59(1), 21-30 (2010).
    • (2010) Gut , vol.59 , Issue.1 , pp. 21-30
    • Straumann, A.1    Conus, S.2    Grzonka, P.3
  • 31
    • 0029148025 scopus 로고
    • Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo
    • Collins PD, Marleau S, Griffiths-Johnson DA, Jose PJ, Williams TJ: Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo. J. Exp. Med. 182(4), 1169-1174 (1995)
    • (1995) J. Exp. Med. , vol.182 , Issue.4 , pp. 1169-1174
    • Collins, P.D.1    Marleau, S.2    Griffiths-Johnson, D.A.3    Jose, P.J.4    Williams, T.J.5
  • 32
    • 33750508779 scopus 로고    scopus 로고
    • Nasal IL-5 levels determine the response to anti-IL-5 treatment in patients with nasal polyps
    • Gevaert P, Lang-Loidolt D, Lackner A et al.: Nasal IL-5 levels determine the response to anti-IL-5 treatment in patients with nasal polyps. J. Allergy Clin. Immunol. 118, 1133-1141 (2006).
    • (2006) J. Allergy Clin. Immunol. , vol.118 , pp. 1133-1141
    • Gevaert, P.1    Lang-Loidolt, D.2    Lackner, A.3
  • 33
    • 9644287854 scopus 로고    scopus 로고
    • Rebound eosinophilia after treatment of hypereosinophilic syndrome and eosinophilic gastroenteritis with monoclonal anti-IL-5 antibody SCH55700
    • Kim YJ, Prussin C, Martin B et al.: Rebound eosinophilia after treatment of hypereosinophilic syndrome and eosinophilic gastroenteritis with monoclonal anti-IL-5 antibody SCH55700. J. Allergy Clin. Immunol. 114, 1449-1455 (2004).
    • (2004) J. Allergy Clin. Immunol. , vol.114 , pp. 1449-1455
    • Kim, Y.J.1    Prussin, C.2    Martin, B.3
  • 34
    • 61849155730 scopus 로고    scopus 로고
    • Mepolizumab for prednisone-dependent asthma with sputum eosinophilia
    • Nair P, Pizzichini MM, Kjarsgaard M et al.: Mepolizumab for prednisone-dependent asthma with sputum eosinophilia. N. Engl. J. Med. 360, 985-993 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , pp. 985-993
    • Nair, P.1    Pizzichini, M.M.2    Kjarsgaard, M.3
  • 35
    • 61849086181 scopus 로고    scopus 로고
    • Mepolizumab and exacerbations of refractory eosinophilic asthma
    • Haldar P, Brightling CE, Hargadon B et al.: Mepolizumab and exacerbations of refractory eosinophilic asthma. N. Engl. J. Med. 360, 973-984 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , pp. 973-984
    • Haldar, P.1    Brightling, C.E.2    Hargadon, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.