-
1
-
-
7044238416
-
Neurodegenerative diseases: A decade of discoveries paves the way for therapeutic breakthroughs
-
DOI 10.1038/nm1113
-
MS Forman, JQ Trojanowski, VM Lee: Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs. Nat Med 10, 1055-1063 (2004) (Pubitemid 39424865)
-
(2004)
Nature Medicine
, vol.10
, Issue.10
, pp. 1055-1063
-
-
Forman, M.S.1
Trojanowski, J.Q.2
Lee, V.M.-Y.3
-
2
-
-
33645728523
-
Neurodegenerative diseases: New concepts of pathogenesis and their therapeutic implications
-
DM Skovronsky, VM Lee, JQ Trojanowski: Neurodegenerative diseases: new concepts of pathogenesis and their therapeutic implications. Annu Rev Pathol 1, 151-170 (2006)
-
(2006)
Annu Rev Pathol
, vol.1
, pp. 151-170
-
-
Skovronsky, D.M.1
Lee, V.M.2
Trojanowski, J.Q.3
-
3
-
-
33744946694
-
The role of biomarkers in clinical trials for Alzheimer disease
-
DOI 10.1097/01.wad.0000191420.61260.a8, PII 0000209320060100000003
-
LJ Thal, K Kantarci, EM Reiman, WE Klunk, MW Weiner, H Zetterberg, D Galasko, D Praticò, S Griffin, D Schenk, E Siemers: The role of biomarkers in clinical trials for Alzheimer's disease. Alzheimer Dis Assoc Disord 20, 6-15 (2006) (Pubitemid 44356888)
-
(2006)
Alzheimer Disease and Associated Disorders
, vol.20
, Issue.1
, pp. 6-15
-
-
Thal, L.J.1
Kantarci, K.2
Reiman, E.M.3
Klunk, W.E.4
Weiner, M.W.5
Zetterberg, H.6
Galasko, D.7
Pratico, D.8
Griffin, S.9
Schenk, D.10
Siemers, E.11
-
4
-
-
37349048311
-
Biomarkers for early detection of Alzheimer pathology
-
DOI 10.1159/000109754
-
CM Clark, C Davatzikos, A Borthakur, A Newberg, S Leight, VM Lee, JQ Trojanowski: Biomarkers for early detection of Alzheimer pathology. Neurosignals 16, 11-18 (2008) (Pubitemid 350308316)
-
(2008)
NeuroSignals
, vol.16
, Issue.1
, pp. 11-18
-
-
Clark, C.M.1
Davatzikos, C.2
Borthakur, A.3
Newberg, A.4
Leight, S.5
Lee, V.M.-Y.6
Trojanowski, J.Q.7
-
5
-
-
11044230530
-
Genomic characterization of Alzheimer's disease and genotype-related phenotypic analysis of biological markers in dementia
-
DOI 10.1517/14622416.5.8.1049
-
R Cacabelos: Genomic characterization of Alzheimer's disease and genotype-related phenotypic analysis of biological markers in dementia. Pharmacogenomics 5, 1049-1105 (2004) (Pubitemid 40045250)
-
(2004)
Pharmacogenomics
, vol.5
, Issue.8
, pp. 1049-1105
-
-
Cacabelos, R.1
-
6
-
-
41149125591
-
Pharmacogenomics and therapeutic prospects in dementia
-
DOI 10.1007/s00406-007-1006-x
-
R Cacabelos: Pharmacogenomics and therapeutic prospects in dementia. Eur Arch Psychiatry Clin Neurosci 258, 28-47 (2008) (Pubitemid 351424036)
-
(2008)
European Archives of Psychiatry and Clinical Neuroscience
, vol.258
, Issue.SUPPL. 1
, pp. 28-47
-
-
Cacabelos, R.1
-
7
-
-
0033850870
-
Pharmacological treatment of alzheimer disease: From psychotropic drugs and cholinesterase inhibitors to pharmacogenomics
-
R Cacabelos, A Alvarez, V Lombardi, L Fernández-Novoa, L Corzo, P Pérez, M Laredo, V Pichel, A Hernández, M Varela, J Figueroa, J Jr Prous, M Windisch, C Vigo: Pharmacological treatment of Alzheimer disease: from psychotropic drugs and cholinesterase inhibitors to pharmacogenomics. Drugs Today (Barc) 36, 415-499 (2000)
-
(2000)
Drugs Today (Barc)
, vol.36
, pp. 415-499
-
-
Cacabelos, R.1
Alvarez, A.2
Lombardi, V.3
Fernández-Novoa, L.4
Corzo, L.5
Pérez, P.6
Laredo, M.7
Pichel, V.8
Hernández, A.9
Varela, M.10
Figueroa, J.11
Prous Jr., J.12
Windisch, M.13
Vigo, C.14
-
8
-
-
0037013327
-
Intracellular amyloid-β1-42, but not extracellular soluble amyloid-β peptides, induces neuronal apoptosis
-
DOI 10.1074/jbc.M200887200
-
P Kienlen-Campard, S Miolet, B Tasiaux, JN Octave: Intracellular amyloid-beta 1-42 but not extracellular soluble amyloid-beta peptides induces neuronal apoptosis. J Biol Chem 277, 15666-15670 (2002) (Pubitemid 34967839)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.18
, pp. 15666-15670
-
-
Kienlen-Campard, P.1
Miolet, S.2
Tasiaux, B.3
Octave, J.-N.4
-
9
-
-
33746310315
-
Alzheimer's disease
-
DOI 10.1016/S0140-6736(06)69113-7, PII S0140673606691137
-
K Blennow, MJ de Leon, H Zetterberg: Alzheimer's disease. Lancet 368, 387-403 (2006) (Pubitemid 44108123)
-
(2006)
Lancet
, vol.368
, Issue.9533
, pp. 387-403
-
-
Blennow, K.1
De Leon, M.J.2
Zetterberg, H.3
-
10
-
-
19944375450
-
Tau pathology in Alzheimer disease and other tauopathies
-
DOI 10.1016/j.bbadis.2004.09.008, PII S0925443904001784
-
K Iqbal, AC Alonso, S Chen, MO Chohan, E El-Akkad, CX Gong, S Khatoon, B Li, F Liu, A Rahman, H Tanimukai I Grundke-Iqbal: Tau pathology in Alzheimer disease and other tauopathies. Biochim. Biophys Acta 1739, 198-210 (2005) (Pubitemid 40018538)
-
(2005)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1739
, Issue.2
, pp. 198-210
-
-
Iqbal, K.1
Del C. Alonso, A.2
Chen, S.3
Chohan, M.O.4
El-Akkad, E.5
Gong, C.-X.6
Khatoon, S.7
Li, B.8
Liu, F.9
Rahman, A.10
Tanimukai, H.11
Grundke-Iqbal, I.12
-
11
-
-
0041689948
-
Caspase cleavage of tau: Linking amyloid and neurofibrillary tangles in Alzheimer's disease
-
DOI 10.1073/pnas.1630428100
-
TC Gamblin, F Chen, A Zambrano, A Abraha, S Lagalwar, AL Guillozet, M Lu, Y Fu, F Garcia-Sierra, N LaPointe, R Miller, RW Berry, LI Binder, VL Cryns: Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease. Proc Natl Acad Sci U S A 100, 10032-10037 (2003) (Pubitemid 37087063)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.17
, pp. 10032-10037
-
-
Gamblin, T.C.1
Chen, F.2
Zambrano, A.3
Abraha, A.4
Lagalwar, S.5
Guillozet, A.L.6
Lu, M.7
Fu, Y.8
Garcia-Sierra, F.9
LaPointe, N.10
Miller, R.11
Berry, R.W.12
Binder, L.I.13
Cryns, V.L.14
-
12
-
-
34248187134
-
Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders
-
DOI 10.2741/2130
-
C Mancuso, G Scapagnini, D Currò, AM Giuffrida Stella, C De Marco, DA Butterfield, V Calabrese: Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders. Front Biosci 12, 1107-1123 (2007) (Pubitemid 46846882)
-
(2007)
Frontiers in Bioscience
, vol.12
, Issue.3
, pp. 1107-1123
-
-
Mancuso, C.1
Scapagnini, G.2
Curro, D.3
Giuffrida Stella, A.M.4
De Marco, C.5
Butterfield, D.A.6
Calabrese, V.7
-
13
-
-
1242264290
-
The pharmacogenomics of Alzheimer's disease
-
DOI 10.1016/j.arr.2003.07.003
-
V Crentsil: The pharmacogenomics of Alzheimer's disease. Ageing Res Rev 3, 153-169 (2004) (Pubitemid 38232679)
-
(2004)
Ageing Research Reviews
, vol.3
, Issue.2
, pp. 153-169
-
-
Crentsil, V.1
-
14
-
-
0036434139
-
Pharmacogenomics for the treatment of dementia
-
DOI 10.1080/078538902320772115
-
R Cacabelos: Pharmacogenomics for the treatment of dementia. Ann Med 34, 357-379 (2002) (Pubitemid 35351825)
-
(2002)
Annals of Medicine
, vol.34
, Issue.5
, pp. 357-379
-
-
Cacabelos, R.1
-
15
-
-
0027327267
-
Association of apolipoprotein E allele ε4 with late-onset familial and sporadic Alzheimer's disease
-
AM, Saunders, WJ Strittmatter, D Schmechel, PH George-Hyslop, MA Pericak-Vance, SH Joo, BL Rosi, JF Gusella, DR Crapper-MacLachlan, MJ Alberts: Association of apolipoprotein E allele ε4 with late-onset familial and sporadic Alzheimer's disease. Neurology 43, 1467-1472 (1993) (Pubitemid 23230526)
-
(1993)
Neurology
, vol.43
, Issue.8
, pp. 1467-1472
-
-
Saunders, A.M.1
Strittmatter, W.J.2
Schmechel, D.3
St. George-Hyslop, P.H.4
Pericak-Vance, M.A.5
Joo, S.H.6
Rosi, B.L.7
Gusella, J.F.8
Crapper-MacLachlan, D.R.9
Alberts, M.J.10
Hulette, C.11
Crain, B.12
Goldgaber, D.13
Roses, A.D.14
-
16
-
-
55049142500
-
Genome-wide association analysis reveals putative alzheimer's disease susceptibility loci in addition to APOE
-
L Bertram, C Lange, K Mullin, M Parkinson, M Hsiao, MF Hogan, BM Schjeide, B Hooli, J Divito, I Ionita, H Jiang, N Laird, T Moscarillo, KL Ohlsen, K Elliott, X Wang, D Hu-Lince, M Ryder, A Murphy, SL Wagner, D Blacker, KD Becker, RE Tanzi: Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. Am J Hum Genet 83, 623-632 (2008)
-
(2008)
Am J Hum Genet
, vol.83
, pp. 623-632
-
-
Bertram, L.1
Lange, C.2
Mullin, K.3
Parkinson, M.4
Hsiao, M.5
Hogan, M.F.6
Schjeide, B.M.7
Hooli, B.8
Divito, J.9
Ionita, I.10
Jiang, H.11
Laird, N.12
Moscarillo, T.13
Ohlsen, K.L.14
Elliott, K.15
Wang, X.16
Hu-Lince, D.17
Ryder, M.18
Murphy, A.19
Wagner, S.L.20
Blacker, D.21
Becker, K.D.22
Tanzi, R.E.23
more..
-
17
-
-
28244435928
-
Candidate genes for late-onset Alzheimer's disease: Focus on chromosome 12
-
DOI 10.1016/j.mad.2005.08.004, PII S0047637405002009
-
F Panza, AM Colacicco, A D'Introno, C Capurso, M Liaci, SA Capurso, A Capurso, V Solfrizzi: Candidate genes for late-onset Alzheimer's disease: focus on chromosome 12. Mech Ageing Dev 127, 36-47 (2006) (Pubitemid 41713512)
-
(2006)
Mechanisms of Ageing and Development
, vol.127
, Issue.1
, pp. 36-47
-
-
Panza, F.1
Colacicco, A.M.2
D'Introno, A.3
Capurso, C.4
Liaci, M.5
Capurso, S.A.6
Capurso, A.7
Solfrizzi, V.8
-
18
-
-
60549101350
-
GAB2 as an alzheimer disease susceptibility gene: Follow-up of genomewide association results
-
BM Schjeide, B Hooli, M Parkinson, MF Hogan, J DiVito, K Mullin, D Blacker, RE Tanzi, L Bertram: GAB2 as an Alzheimer disease susceptibility gene: follow-up of genomewide association results. Arch Neurol 66, 250-254 (2009)
-
(2009)
Arch Neurol
, vol.66
, pp. 250-254
-
-
Schjeide, B.M.1
Hooli, B.2
Parkinson, M.3
Hogan, M.F.4
DiVito, J.5
Mullin, K.6
Blacker, D.7
Tanzi, R.E.8
Bertram, L.9
-
19
-
-
33644694711
-
The multiple function of Grb2 associated binder (Gab) adaptor/scaffolding protein in immune cell signaling
-
DOI 10.1016/j.imlet.2005.11.017, PII S0165247805003627, Signal and Signaling Processing in the Immune System
-
G Sármay, A Angyal, A Kertész, M Maus, D Medgyesi: The multiple function of Grb2 associated binder (Gab) adaptor/scaffolding protein in immune cell signaling. Immunol Lett 104, 76-82 (2006) (Pubitemid 43330712)
-
(2006)
Immunology Letters
, vol.104
, Issue.1-2
, pp. 76-82
-
-
Sarmay, G.1
Angyal, A.2
Kertesz, A.3
Maus, M.4
Medgyesi, D.5
-
20
-
-
0037181483
-
The gift of Gab
-
DOI 10.1016/S0014-5793(02)02425-0, PII S0014579302024250
-
Y Liu, LR Rohrschneider: The gift of Gab. FEBS Lett 515, 1-7 (2002) (Pubitemid 34273887)
-
(2002)
FEBS Letters
, vol.515
, Issue.1-3
, pp. 1-7
-
-
Liu, Y.1
Rohrschneider, L.R.2
-
21
-
-
49649119504
-
Phosphorylation regulates tau interactions with src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cγ1, grb2, and src family kinases
-
CH Reynolds, CJ Garwood, S Wray, C Price, S Kellie, T Perera, M Zvelebil, A Yang, PW Sheppard, IM Varndell, DP Hanger, BH Anderton: Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cγ1, Grb2, and Src family kinases. J Biol Chem 283, 18177-18186 (2008)
-
(2008)
J Biol Chem
, vol.283
, pp. 18177-18186
-
-
Reynolds, C.H.1
Garwood, C.J.2
Wray, S.3
Price, C.4
Kellie, S.5
Perera, T.6
Zvelebil, M.7
Yang, A.8
Sheppard, P.W.9
Varndell, I.M.10
Hanger, D.P.11
Anderton, B.H.12
-
22
-
-
34250304714
-
Amyloid precursor protein and presenilin1 interact with the adaptor GRB2 and modulate ERK1,2 signaling
-
DOI 10.1074/jbc.M610146200
-
M Nizzari, V Venezia, E Repetto, V Caorsi, R Magrassi, MC Gagliani, P Carlo, T Florio, G Schettini, C Tacchetti, T Russo, A Diaspro, C Russo: Amyloid precursor protein and presenilin1 interact with the adaptor GRB2 and modulate ERK 1, 2 signaling. J Biol Chem 282, 13833-13844 (2007) (Pubitemid 47100564)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.18
, pp. 13833-13844
-
-
Nizzari, M.1
Venezia, V.2
Repetto, E.3
Caorsi, V.4
Magrassi, R.5
Gagliani, M.C.6
Carlo, P.7
Florio, T.8
Schettini, G.9
Tacchetti, C.10
Russo, T.11
Diaspro, A.12
Russo, C.13
-
23
-
-
37649011164
-
Alzheimer's disease and genetics of inflammation: A pharmacogenomic vision
-
S Vasto, G Candore, G Duro, D Lio, MP Grimaldi, C Caruso: Alzheimer's disease and genetics of inflammation: a pharmacogenomic vision. Pharmacogenomics 8, 1735-1745 (2007)
-
(2007)
Pharmacogenomics
, vol.8
, pp. 1735-1745
-
-
Vasto, S.1
Candore, G.2
Duro, G.3
Lio, D.4
Grimaldi, M.P.5
Caruso, C.6
-
24
-
-
33646073705
-
Association between the HLA-A2 allele and alzheimer disease
-
F Listì, G Candore, CR Balistreri, MP Grimaldi, V Orlando, S Vasto, G Colonna-Romano, D Lio, F Licastro, C Franceschi, C Caruso: Association between the HLA-A2 allele and Alzheimer disease. Rejuvenation Res 9, 99-101 (2006)
-
(2006)
Rejuvenation Res
, vol.9
, pp. 99-101
-
-
Listì, F.1
Candore, G.2
Balistreri, C.R.3
Grimaldi, M.P.4
Orlando, V.5
Vasto, S.6
Colonna-Romano, G.7
Lio, D.8
Licastro, F.9
Franceschi, C.10
Caruso, C.11
-
25
-
-
53749105025
-
Association between the interleukin-1beta polymorphisms and alzheimer's disease: A systematic review and meta-analysis
-
D Di Bona, A Plaia, S Vasto, L Cavallone, F Lescai, C Franceschi, F Licastro, G Colonna-Romano, D Lio, G Candore, C Caruso: Association between the interleukin-1beta polymorphisms and Alzheimer's disease: a systematic review and meta-analysis. Brain Res Rev 59, 155-163 (2008)
-
(2008)
Brain Res Rev
, vol.59
, pp. 155-163
-
-
Di Bona, D.1
Plaia, A.2
Vasto, S.3
Cavallone, L.4
Lescai, F.5
Franceschi, C.6
Licastro, F.7
Colonna-Romano, G.8
Lio, D.9
Candore, G.10
Caruso, C.11
-
26
-
-
0035691112
-
CSF total tau, Aβ42 and phosphorylated tau protein as biomarkers for Alzheimer's disease
-
K Blennow, E Vanmechelen, H Hampel: CSF total tau, Abeta42 and phosphorylated tau protein as biomarkers for Alzheimer's disease. Mol Neurobiol 24, 87-97 (2001) (Pubitemid 34066679)
-
(2001)
Molecular Neurobiology
, vol.24
, Issue.1-3
, pp. 87-97
-
-
Blennow, K.1
Vanmechelen, E.2
Hampel, H.3
-
27
-
-
0141738373
-
CSF markers for incipient Alzheimer's disease
-
DOI 10.1016/S1474-4422(03)00530-1
-
K Blennow, H Hampel: CSF markers for incipient Alzheimer's disease. Lancet Neurol 2, 605-613 (2003) (Pubitemid 37162569)
-
(2003)
Lancet Neurology
, vol.2
, Issue.10
, pp. 605-613
-
-
Blennow, K.1
Hampel, H.2
-
28
-
-
0346124139
-
Cerebrospinal Fluid Tau and β-Amyloid: How Well Do These Biomarkers Reflect Autopsy-Confirmed Dementia Diagnoses?
-
DOI 10.1001/archneur.60.12.1696
-
CM Clark, S Xie, J Chittams, D Ewbank, E Peskind, D Galasko, JC Morris, DW Jr McKeel, M Farlow, SL Weitlauf, J Quinn, J Kaye, D Knopman, H Arai, RS Doody, C DeCarli, S Leight, VM Lee, JQ Trojanowski: Cerebrospinal fluid tau and beta-amyloid: how well do these biomarkers reflect autopsy-confirmed dementia diagnoses? Arch Neurol 60, 1696-1702 (2003) (Pubitemid 37521622)
-
(2003)
Archives of Neurology
, vol.60
, Issue.12
, pp. 1696-1702
-
-
Clark, C.M.1
Xie, S.2
Chittams, J.3
Ewbank, D.4
Peskind, E.5
Galasko, D.6
Morris, J.C.7
McKeel Jr., D.W.8
Farlow, M.9
Weitlauf, S.L.10
Quinn, J.11
Kaye, J.12
Knopman, D.13
Arai, H.14
Doody, R.S.15
DeCarli, C.16
Leight, S.17
Lee, V.M.-Y.18
Trojanowski, J.Q.19
-
29
-
-
0030698647
-
Elevated cerebrospinal fluid tau protein level as a predictor of dementia in memory-impaired individuals
-
H Arai, T Nakagawa, Y Kosaka, M Higuchi, T Matsui, N Okamura, M Tashiro, H Sasaki: Elevated cerebrospinal fluid tau protein level as a predictor of dementia in memory-impaired patients. Alzheimer's Research 3, 211-213 (1997) (Pubitemid 27475104)
-
(1997)
Alzheimer's Research
, vol.3
, Issue.5
, pp. 211-213
-
-
Arai, H.1
Nakagawa, T.2
Kosaka, Y.-I.3
Higuchi, M.4
Matsui, T.5
Okamura, N.6
Tashiro, M.7
Sasaki, H.8
-
30
-
-
0013359320
-
Cerebrospinal fluid tau levels in Alzheimer's disease are elevated when compared with vascular dementia but do not correlate with measures of cerebral atrophy
-
DOI 10.1016/S0165-1781(03)00197-5, PII S0165178103001975
-
P Schönknecht, J Pantel, T Hartmann, E Werle, M Volkmann, M Essig, M Amann, N Zanabili, H Bardenheuer, A Hunt, J Schröder: Cerebrospinal fluid tau levels in Alzheimer's disease are elevated when compared with vascular dementia but do not correlate with measures of cerebral atrophy. Psychiatry Res 120, 231-238 (2003) (Pubitemid 38366050)
-
(2003)
Psychiatry Research
, vol.120
, Issue.3
, pp. 231-238
-
-
Schonknecht, P.1
Pantel, J.2
Hartmann, T.3
Werle, E.4
Volkmann, M.5
Essig, M.6
Amann, M.7
Zanabili, N.8
Bardenheuer, H.9
Hunt, A.10
Schroder, J.11
-
31
-
-
0035066999
-
Tracking of Alzheimer's disease progression with cerebrospinal fluid tau protein phosphorylated at threonine 231 [3]
-
DOI 10.1002/ana.111
-
H Hampel, K Buerger, R Kohnken, SJ Teipel, R Zinkowski, HJ Moeller, SI Rapoport, P Davies: Tracking of Alzheimer's disease progression with cerebrospinal fluid tau protein phosphorylated at threonine 231. Ann Neurol 49, 545-546 (2001) (Pubitemid 32281345)
-
(2001)
Annals of Neurology
, vol.49
, Issue.4
, pp. 545-546
-
-
Hampel, H.1
Buerger, K.2
Kohnken, R.3
Teipel, S.J.4
Zinkowski, R.5
Moeller, H.-J.6
Rapoport, S.I.7
Davies, P.8
-
32
-
-
0030967243
-
Assessment of CSF levels of tau protein in mildly demented patients with Alzheimer's disease
-
D Galasko, C Clark, L Chang, B Miller, RC Green, R Motter, P Seubert: Assessment of CSF levels of tau protein in mildly demented patients with Alzheimer's disease. Neurology 48, 632-635 (1997) (Pubitemid 27120097)
-
(1997)
Neurology
, vol.48
, Issue.3
, pp. 632-635
-
-
Galasko, D.1
Clark, C.2
Chang, L.3
Miller, B.4
Green, R.C.5
Motter, R.6
Seubert, P.7
-
33
-
-
0035108753
-
Evaluation of CSFtau and CSF-abeta42 as diagnostic markers for alzheimer disease in clinical practice
-
N Andreasen, L Minthon, P Davidsson, E Vanmechelen, H Vanderstichele, B Winblad, K Blennow: Evaluation of CSFtau and CSF-Abeta42 as diagnostic markers for Alzheimer disease in clinical practice. Arch Neurol 58, 373-379 (2005)
-
(2005)
Arch Neurol
, vol.58
, pp. 373-379
-
-
Andreasen, N.1
Minthon, L.2
Davidsson, P.3
Vanmechelen, E.4
Vanderstichele, H.5
Winblad, B.6
Blennow, K.7
-
34
-
-
39749105380
-
Toward a plasma marker for Alzheimer disease: Some progress, but still a long way to go
-
DOI 10.1212/01.wnl.0000299905.05595.68, PII 0000611420080219000002
-
HA Crystal, P Davies: Toward a plasma marker for Alzheimer disease: Some progress, but still a long way to go. Neurology 70, 586-587 (2008) (Pubitemid 351294634)
-
(2008)
Neurology
, vol.70
, Issue.8
, pp. 586-587
-
-
Crystal, H.A.1
Davies, P.2
-
35
-
-
29244432517
-
Problems associated with biological markers of Alzheimer's disease
-
DOI 10.1007/s11064-005-8827-7
-
HJ Frey, KM Mattila, MA Korolainen, T Pirttila: Problems associated with biological markers of Alzheimer's disease. Neurochem Res 30, 1501-1510 (2005) (Pubitemid 41818932)
-
(2005)
Neurochemical Research
, vol.30
, Issue.12
, pp. 1501-1510
-
-
Frey, H.J.1
Mattila, K.M.2
Korolainen, M.A.3
Pirttila, T.4
-
36
-
-
47549117283
-
Biochemical markers in persons with preclinical familial alzheimer disease
-
JM Ringman, SG Younkin, D Pratico, JM Ringman, SG Younkin, D Pratico: Biochemical markers in persons with preclinical familial Alzheimer disease. Neurology 71, 85-92 (2008)
-
(2008)
Neurology
, vol.71
, pp. 85-92
-
-
Ringman, J.M.1
Younkin, S.G.2
Pratico, D.3
Ringman, J.M.4
Younkin, S.G.5
Pratico, D.6
-
37
-
-
67649544381
-
Biomarker discovery in neurodegenerative diseases: A proteomic approach
-
M Shi, WM Caudle, J Zhang: Biomarker discovery in neurodegenerative diseases: a proteomic approach. Neurobiol Dis 35, 157-164 (2009)
-
(2009)
Neurobiol Dis
, vol.35
, pp. 157-164
-
-
Shi, M.1
Caudle, W.M.2
Zhang, J.3
-
38
-
-
42949119345
-
CSF multianalyte profile distinguishes Alzheimer and Parkinson diseases
-
DOI 10.1309/W01Y0B808EMEH12L
-
J Zhang, I Sokal, ER Peskind, JF Quinn, J Jankovic, C Kenney, KA Chung, SP Millard, JG Nutt, TJ Montine: CSF multianalyte profile distinguishes Alzheimer and Parkinson diseases. Am J Clin Pathol 129, 526-529 (2008) (Pubitemid 352029270)
-
(2008)
American Journal of Clinical Pathology
, vol.129
, Issue.4
, pp. 526-529
-
-
Zhang, J.1
Sokal, I.2
Peskind, E.R.3
Quinn, J.F.4
Jankovic, J.5
Kenney, C.6
Chung, K.A.7
Millard, S.P.8
Nutt, J.G.9
Montine, T.J.10
-
39
-
-
43849111501
-
Identification of a novel panel of cerebrospinal fluid biomarkers for Alzheimer's disease
-
DOI 10.1016/j.neurobiolaging.2007.01.011, PII S0197458007000188
-
AH Simonsen, J McGuire, VN Podust, H Davies, L Minthon, I Skoog, N Andreasen, A Wallin, G Waldemar, K Blennow: Identification of a novel panel of cerebrospinal fluid biomarkers for Alzheimer's disease. Neurobiol Aging 29, 961-968 (2008) (Pubitemid 351697984)
-
(2008)
Neurobiology of Aging
, vol.29
, Issue.7
, pp. 961-968
-
-
Simonsen, A.H.1
McGuire, J.2
Podust, V.N.3
Davies, H.4
Minthon, L.5
Skoog, I.6
Andreasen, N.7
Wallin, A.8
Waldemar, G.9
Blennow, K.10
-
40
-
-
33750596715
-
Proteome-based plasma biomarkers for Alzheimer's disease
-
DOI 10.1093/brain/awl279
-
A Hye, S Lynham, M Thambisetty, M Causevic, J Campbell, HL Byers, C Hooper, F Rijsdijk, SJ Tabrizi, S Banner, CE Shaw, C Foy, M Poppe, N Archer, G Hamilton, J Powell, RG Brown, P Sham, M Ward, S Lovestone: Proteome-based plasma biomarkers for Alzheimer's disease. Brain 129, 3042-3050 (2006) (Pubitemid 44684524)
-
(2006)
Brain
, vol.129
, Issue.11
, pp. 3042-3050
-
-
Hye, A.1
Lynham, S.2
Thambisetty, M.3
Causevic, M.4
Campbell, J.5
Byers, H.L.6
Hooper, C.7
Rijsdijk, F.8
Tabrizi, S.J.9
Banner, S.10
Shaw, C.E.11
Foy, C.12
Poppe, M.13
Archer, N.14
Hamilton, G.15
Powell, J.16
Brown, R.G.17
Sham, P.18
Ward, M.19
Lovestone, S.20
more..
-
41
-
-
34547813002
-
Serum biomarkers for Alzheimer's disease: Proteomic discovery
-
DOI 10.1016/j.biopha.2007.05.009, PII S0753332207001138
-
DC German: Serum biomarkers for Alzheimer's disease: proteomic discovery. Biomed Pharmacother 61, 383-389 (2007) (Pubitemid 47239345)
-
(2007)
Biomedicine and Pharmacotherapy
, vol.61
, Issue.7
, pp. 383-389
-
-
German, D.C.1
Gurnani, P.2
Nandi, A.3
Garner, H.R.4
Fisher, W.5
Diaz-Arrastia, R.6
O'Suilleabhain, P.7
Rosenblatt, K.P.8
-
42
-
-
33847776233
-
Association between the polymorphism of CCR5 and Alzheimer's disease: Results of a study performed on male and female patients from northern Italy
-
DOI 10.1196/annals.1386.012, Estrogens and Human Diseases
-
CR Balistreri, MP Grimaldi, S Vasto, F Listi, M Chiappelli, F Licastro, D Lio, C Caruso, G Candore: Association between the polymorphism of CCR5 and Alzheimer's disease: results of a study performed on male and female patients from Northern Italy. Ann N Y Acad Sci 1089, 454-461 (2006) (Pubitemid 47092067)
-
(2006)
Annals of the New York Academy of Sciences
, vol.1089
, pp. 454-461
-
-
Balistreri, C.R.1
Grimaldi, M.P.2
Vasto, S.3
Listi, F.4
Chiappelli, M.5
Licastro, F.6
Lio, D.7
Caruso, C.8
Candore, G.9
-
43
-
-
51349095918
-
Alzheimer's disease: New diagnostic and therapeutic tools
-
M Racchi, D Uberti, S Govoni, M Memo, C Lanni, S Vasto, G Candore, C Caruso, L Romeo, G Scapagnini: Alzheimer's disease: new diagnostic and therapeutic tools. Immun Ageing 5, 7 (2008)
-
(2008)
Immun Ageing
, vol.5
, pp. 7
-
-
Racchi, M.1
Uberti, D.2
Govoni, S.3
Memo, M.4
Lanni, C.5
Vasto, S.6
Candore, G.7
Caruso, C.8
Romeo, L.9
Scapagnini, G.10
-
44
-
-
33745996107
-
Identification of a mutant-like conformation of p53 in fibroblasts from sporadic Alzheimer's disease patients
-
DOI 10.1016/j.neurobiolaging.2005.06.013, PII S0197458005002010
-
D Uberti, C Lanni, T Carsana, S Francisconi, C Missale, M Racchi, S Govoni, M Memo: Identification of a mutant-like conformation of p53 in fibroblasts from sporadic Alzheimer's disease patients. Neurobiol Aging 27, 1193-1201 (2006) (Pubitemid 44067307)
-
(2006)
Neurobiology of Aging
, vol.27
, Issue.9
, pp. 1193-1201
-
-
Uberti, D.1
Lanni, C.2
Carsana, T.3
Francisconi, S.4
Missale, C.5
Racchi, M.6
Govoni, S.7
Memo, M.8
-
45
-
-
40449133643
-
Conformationally altered p53: A putative peripheral marker for Alzheimer's disease
-
DOI 10.1159/000113704
-
D Uberti, C Lanni, M Racchi, S Govoni, M Memo: Conformationally altered p53: a putative peripheral marker for Alzheimer's disease. Neurodegener Dis 5, 209-211 (2008) (Pubitemid 351347852)
-
(2008)
Neurodegenerative Diseases
, vol.5
, Issue.3-4
, pp. 209-211
-
-
Uberti, D.1
Lanni, C.2
Racchi, M.3
Govoni, S.4
Memo, M.5
-
46
-
-
34548585114
-
Unfolded p53: A potential biomarker for Alzheimer's disease
-
The Multifaceted Aspects of Alzheimer's Disease: From Social to Molecular Problems
-
C Lanni, D Uberti, M Racchi, S Govoni, M Memo: Unfolded p53: a potential biomarker for Alzheimer's disease. J Alzheimers Dis 12, 93-99 (2007) (Pubitemid 47396308)
-
(2007)
Journal of Alzheimer's Disease
, vol.12
, Issue.1
, pp. 93-99
-
-
Lanni, C.1
Uberti, D.2
Racchi, M.3
Govoni, S.4
Memo, M.5
-
47
-
-
43949090196
-
Conformationally altered p53: A novel Alzheimer's disease marker?
-
DOI 10.1038/sj.mp.4002060, PII 4002060
-
C Lanni, M Racchi, G Mazzini, A Ranzenigo, R Polotti, E Sinforiani, L Olivari, M Barcikowska, M Styczynska, J Kuznicki, A Szybinska, S Govoni, M Memo, D Uberti: Conformationally altered p53: a novel Alzheimer's disease marker? Mol Psychiatry 13, 641-647 (2008) (Pubitemid 351704936)
-
(2008)
Molecular Psychiatry
, vol.13
, Issue.6
, pp. 641-647
-
-
Lanni, C.1
Racchi, M.2
Mazzini, G.3
Ranzenigo, A.4
Polotti, R.5
Sinforiani, E.6
Olivari, L.7
Barcikowska, M.8
Styczynska, M.9
Kuznicki, J.10
Szybinska, A.11
Govoni, S.12
Memo, M.13
Uberti, D.14
-
48
-
-
0028339544
-
Attenuated protein kinase C activity and translocation in Alzheimer's disease brain
-
DOI 10.1016/0197-4580(94)90023-X
-
HY Wang, MR Pisano, E Friedman: Attenuated protein kinase C activity and translocation in Alzheimer's disease brain. Neurobiol Aging 15, 293-298 (1994) (Pubitemid 24194869)
-
(1994)
Neurobiology of Aging
, vol.15
, Issue.3
, pp. 293-298
-
-
Wang, H.-Y.1
Pisano, M.R.2
Friedman, E.3
-
49
-
-
0032865258
-
Protein kinase C anchoring deficit in postmortem brains of Alzheimer's disease patients
-
DOI 10.1006/exnr.1999.7151
-
F Battaini, A Pascale, L Lucchi, GM Pasinetti, S Govoni: Protein kinase C anchoring deficit in postmortem brains of Alzheimer's disease patients. Exp Neurol 159, 559-564 (1999) (Pubitemid 29485243)
-
(1999)
Experimental Neurology
, vol.159
, Issue.2
, pp. 559-564
-
-
Battaini, F.1
Pascale, A.2
Lucchi, L.3
Pasinetti, G.M.4
Govoni, S.5
-
50
-
-
3342934646
-
Therapeutic effects of PKC activators in Alzheimer's disease transgenic mice
-
DOI 10.1073/pnas.0403921101
-
R Etcheberrigaray, M Tan, I Dewachter, C Kuiperi, I Van der Auwera, S Wera: Therapeutic effects of PKC activators in Alzheimer's disease transgenic mice. Proc Natl Acad Sci U S A 101, 11141-11146 (2004) (Pubitemid 38989597)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.30
, pp. 11141-11146
-
-
Etcheberrigaray, R.1
Tan, M.2
Dewachtert, I.3
Kuiperi, C.4
Van Der Auwera, I.5
Wera, S.6
Qiao, L.7
Bank, B.8
Nelson, T.J.9
Kozikowski, A.P.10
Van Leuven, F.11
Alkon, D.L.12
-
51
-
-
0031985192
-
Peripheral markers in testing pathophysiological hypotheses and diagnosing Alzheimer's disease
-
L Gasparini, M Racchi, G Binetti, M Trabucchi, SB Solerte, D Alkon, R Etcheberrigaray, G Gibson, J Blass, R Paoletti, S Govoni: Peripheral markers in testing pathophysiological hypotheses and diagnosing Alzheimer's disease. FASEB J 12, 17-34 (1998) (Pubitemid 28060268)
-
(1998)
FASEB Journal
, vol.12
, Issue.1
, pp. 17-34
-
-
Gasparini, L.1
Racchi, M.2
Binetti, G.3
Trabucchi, M.4
Solerte, S.B.5
Alkon, D.6
Etcheberrigaray, R.7
Gibson, G.8
Blass, J.9
Paoletti, R.10
Govoni, S.11
-
52
-
-
34548588380
-
Redox proteomics identification of oxidatively modified brain proteins in Alzheimer's disease and mild cognitive impairment: Insights into the progression of this dementing disorder
-
The Multifaceted Aspects of Alzheimer's Disease: From Social to Molecular Problems
-
DA Butterfield, R Sultana: Redox proteomics identification of oxidatively modified brain proteins in Alzheimer's disease and mild cognitive impairment: insights into the progression of this dementing disorder. J Alzheimers Dis 12, 61-72 (2007) (Pubitemid 47396301)
-
(2007)
Journal of Alzheimer's Disease
, vol.12
, Issue.1
, pp. 61-72
-
-
Butterfield, D.A.1
Sultana, R.2
-
53
-
-
33947644871
-
Protein oxidation and lipid peroxidation in brain of subjects with Alzheimer's disease: Insights into mechanism of neurodegeneration from redox proteomics
-
R Sultana, M Perluigi, DA Butterfield: Protein oxidation and lipid peroxidation in brain of subjects with Alzheimer's disease: insights into mechanism of neurodegeneration from redox proteomics. Antioxid Redox Signal 8, 2021-2037 (2006) (Pubitemid 46499264)
-
(2006)
Antioxidants and Redox Signaling
, vol.8
, Issue.11-12
, pp. 2021-2037
-
-
Sultana, R.1
Perluigi, M.2
Butterfield, D.A.3
-
54
-
-
0008881566
-
The heme oxygenase system and its functions in the brain
-
MD Maines: The heme oxygenase system and its functions in the brain. Cell Mol Biol (Noisy-le-grand) 46, 573-585 (2000)
-
(2000)
Cell Mol Biol (Noisy-le-grand)
, vol.46
, pp. 573-585
-
-
Maines, M.D.1
-
55
-
-
0036839590
-
Gene expression profiles of heme oxygenase isoforms in the rat brain
-
DOI 10.1016/S0006-8993(02)03338-3, PII S0006899302033383
-
G Scapagnini, V D'Agata, V Calabrese, A Pascale, C Colombrita, D Alkon, S Cavallaro: Gene expression profiles of heme oxygenase isoforms in the rat brain. Brain Res 954, 51-59 (2002) (Pubitemid 35223440)
-
(2002)
Brain Research
, vol.954
, Issue.1
, pp. 51-59
-
-
Scapagnini, G.1
D'Agata, V.2
Calabrese, V.3
Pascale, A.4
Colombrita, C.5
Alkon, D.6
Cavallaro, S.7
-
56
-
-
33947606911
-
Nitrosative stress, cellular stress response, and thiol homeostasis in patients with Alzheimer's disease
-
V Calabrese, R Sultana, G Scapagnini, E Guagliano, M Sapienza, R Bella, J Kanski, G Pennisi, C Mancuso, AM Stella, DA Butterfield: Nitrosative stress, cellular stress response, and thiol homeostasis in patients with Alzheimer's disease. Antioxid Redox Signal 8, 1975-1986 (2006) (Pubitemid 46489625)
-
(2006)
Antioxidants and Redox Signaling
, vol.8
, Issue.11-12
, pp. 1975-1986
-
-
Calabrese, V.1
Sultana, R.2
Scapagnini, G.3
Guagliano, E.4
Sapienza, M.5
Bella, R.6
Kanski, J.7
Pennisi, G.8
Mancuso, C.9
Stella, A.M.G.10
Butterfield, D.A.11
-
57
-
-
0034052839
-
Overexpression of heme oxygenase in neuronal cells, the possible interaction with tau
-
DOI 10.1074/jbc.275.8.5395
-
A Takeda, G Perry, NG Abraham, BE Dwyer, RK Kutty, JT Laitinen, RB Petersen, MA Smith: Overexpression of heme oxygenase in neuronal cells, the possible interaction with Tau. J Biol Chem 275, 5395-5399 (2000) (Pubitemid 30115170)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.8
, pp. 5395-5399
-
-
Takeda, A.1
Perry, G.2
Abraham, N.G.3
Dwyer, B.E.4
Kutty, R.K.5
Laitinen, J.T.6
Petersen, R.B.7
Smith, M.A.8
-
58
-
-
54749083106
-
Synergistic effect of heme oxygenase-1 and tau genetic variants on alzheimer's disease risk
-
I Mateo, P Sánchez-Juan, E Rodríguez-Rodríguez, J Infante, JL Vázquez-Higuera, I García-Gorostiaga, J Berciano, O Combarros: Synergistic effect of heme oxygenase-1 and tau genetic variants on Alzheimer's disease risk. Dement Geriatr Cogn Disord 26, 339-342 (2008)
-
(2008)
Dement Geriatr Cogn Disord
, vol.26
, pp. 339-342
-
-
Mateo, I.1
Sánchez-Juan, P.2
Rodríguez-Rodríguez, E.3
Infante, J.4
Vázquez-Higuera, J.L.5
García-Gorostiaga, I.6
Berciano, J.7
Combarros, O.8
-
59
-
-
0034724251
-
Evaluation of heme oxygenase-1 as a systemic biological marker of sporadic AD
-
HM Schipper, H Chertkow, K Mehindate, D Frankel, C Melmed, H Bergman: Evaluation of heme oxygenase-1 as a systemic biological marker of sporadic AD. Neurology 54, 1297-1304 (2000) (Pubitemid 30174050)
-
(2000)
Neurology
, vol.54
, Issue.6
, pp. 1297-1304
-
-
Schipper, H.M.1
Chertkow, H.2
Mehindate, K.3
Frankel, D.4
Melmed, C.5
Bergman, H.6
-
60
-
-
0035846536
-
Blood HO-1 mRNA in AD and MCI
-
HM Schipper, Y Mawal, H Chertkow, H Bergman: Blood HO-1 mRNA in AD and MCI. Neurology 57, 2142-2143 (2001) (Pubitemid 33126895)
-
(2001)
Neurology
, vol.57
, Issue.11
, pp. 2142-2143
-
-
Schipper, H.M.1
Mawal, Y.2
Chertkow, H.3
Bergman, H.4
|