Evaluation of heme oxygenase-1 as a systemic biological marker of sporadic AD

Neurology

Volumn 54, Issue 6, 2000, Pages 1297-1304

  Schipper, Hyman M ^a,b,c   Chertkow, H ^a,b,c,d   Mehindate, K ^a   Frankel, D ^a   Melmed, C ^b,c   Bergman, H ^b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d CENTRE DE RECHERCHE   (Canada)

Author keywords

AD; Aging; Biologic marker; Dementia; Diagnosis; Heme oxygenase 1

Indexed keywords

BIOLOGICAL MARKER; HEME OXYGENASE; MESSENGER RNA;

AGED; AGING; ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; ENZYME BLOOD LEVEL; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME REGULATION; FEMALE; HUMAN; HUMAN CELL; LYMPHOCYTE; MAJOR CLINICAL STUDY; MALE; NORTHERN BLOTTING; PRIORITY JOURNAL;

EID: 0034724251     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.54.6.1297     Document Type: Article

References (40)

1. McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984;34:939-944.
2. Galasko D, Hansen L, Katzman R, et al. Clinical-neuropathological correlations in Alzheimer's disease and related dementias. Arch Neurol 1994;51:888-895.
3. Gearing M, Mirra SS, Hedreen JC, et al. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part X. Neuropathology confirmation of the clinical diagnosis of Alzheimer's disease. Neurology 1995;45:461-466.
4. Kennard M. Diagnostic markers for Alzheimer's disease. Neurobiol Aging 1998;19:131-132.
5. Levy R. Aging-associated cognitive decline. Working party of the International Psychogeriatric Association in collaboration with the World Health Organization. Int Psychogeriatr 1994; 6:63-68.
6. Rubin EH, Morris JC, Grant E, Vendegna T. Very mild senile dementia of the Alzheimer type. I. Clinical assessment. Arch Neurol 1989;46:379-382.
7. Chertkow H, Bergman H, Wolfson C, Babins L, Kelner N. Standard neuropsychological tests do not predict development of Alzheimer's disease in individuals with "age-associated cognitive decline." Can J Neurol Sci 1998;25(suppl 1):S27-S28.
8. Dawe B, Procter A, Philpot M. Concepts of mild memory impairment in the elderly and their relationship to dementia - a review. Int J Geriatr Psychiatry 1992;7:473-479.
9. Trojanowski JQ, Growdon JH. A new consensus report on biomarkers for the early antemortem diagnosis of Alzheimer disease: current status, relevance to drug discovery, and recommendations for future research. J Neuropathol Exp Neurol 1998;57:643-644.
10. St. George-Hyslop PH. Role of genetics in tests of genotype, status, and disease progression in early-onset Alzheimer's disease. Neurobiol Aging 1998;19:133-137.
11. Hyman BT. Biomarkers in Alzheimer's disease. Neurobiol Aging 1998;19:159-160.
12. Motter R, Vigo-Pelfrey C, Kholodenko D, et al. Reduction of beta-amyloid peptide 42 in the cerebrospinal fluid of patients with Alzheimer's disease. Ann Neurol 1995;38:643-648.
13. Ida N, Hartmann T, Pantel J, et al. Analysis of heterogeneous betaA4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay. J Biol Chem 1996;271:22908-22914.
14. Hock C, Golombowski S, Naser W, et al. Increased levels of tau protein in cerebrospinal fluid of patients with Alzheimer's disease-Correlation with cognitive impairment. Ann Neurol 1995;37:414-415.
15. de la Monte SM, Volicer L, Hauser SL, et al. Increased levels of neuronal thread protein in cerebrospinal fluid of patients with Alzheimer's disease. Ann Neurol 1992;32:733-742.
16. Iwatsubo T. Amyloid beta protein in plasma as a diagnostic marker for Alzheimer's disease. Neurobiol Aging 1998;19:161-163.
17. Kennard ML, Feldman H, Yamada T, Jefferies WA. Serum levels of the iron binding protein p97 are elevated in Alzheimer's disease. Nat Med 1996;2:1230-1235.
18. Feldman H. Diagnosis of Alzheimer's disease. Presented at the annual meeting of the Royal College of Physicians & Surgeons (Canada); Vancouver; September 25-28, 1997.
19. Tenhunen R, Marver HS, Schmid R. Microsomal heme oxygenase: characterization of the enzyme. J Biol Chem 1969; 244:6388-6394.
20. Stocker R, Yamamoto Y, McDonagh AF, et al. Bilirubin is an antioxidant of possible physiological importance. Science 1987;235:1043-1046.
21. Schipper HM, Bernier L, Mehindate K, et al. Mitochondrial iron sequestration in dopamine-challenged astroglia: role of HO-1 and the permeability transition pore. J Neurochem 1999;72:1802-1811.
22. Schipper HM, Cissé S, Stopa EG. Expression of heme oxygenase-1 in the senescent and Alzheimer-diseased brain. Ann Neurol 1995;37:758-768.
23. Smith MA, Kutty RK, Richey PL, et al. Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease. Am J Pathol 1994;145:42-47.
24. Folstein M, Folstein F, McHugh P. "Mini-mental state": a practical method for grading the cognitive state of patients for the clinician. J Clin Res 1975;12:189-198.
25. Hughes CP, Berg L, Danziger WL, Coben LA, Martin RL. A new clinical scale for the staging of dementia. Br J Psychiatry 1982;140:566-572.
26. Wang GP, Iqbal K, Ducht G, Winblad B, Wisniewski HM, Grundke-Iqbal I. Alzheimer's disease: paired helical filament immunoreactivity in cerebrospinal fluid. Acta Neuropathol 1991;82:6-12.
27. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chlorophorm extraction. Analyt Biochem 1987;162:156-159.
28. Feinberg AP, Vogelstein B. A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity. Analyt Biochem 1984;137:266-267.
29. Noonberg SB, Scott GK, Hunt CA, Benz CC. Detection of triplex-forming RNA oligonucleotides by triplex blotting. BioTechniques 1994;16:1070-1072.
30. Church GM, Gilbert W. Genomic sequencing. Proc Natl Acad Sci USA 1984;81:1991-1995.
31. Menzel DB, Rasmussen RE, Lee E, et al. Human lymphocyte heme oxygenase-1 as a response biomarker to inorganic arsenic. Biochem Biophys Res Commun 1998;250:653-656.
32. Ponka P, Beaumont C, Richardson DR. Function and regulation of transferrin and ferritin. Sem Hematol 1998;35:35-54.
33. Famulari AL, Marschoff ER, Llesuy SF, et al. The antioxidant enzymatic blood profile in Alzheimer's and vascular diseases. Their association and a possible assay to differentiate demented subjects and controls. J Neurol Sci 1996;141:69-78.
34. Kimpara T, Takeda A, Watanabe K, et al. Microsatellite polymorphism in the human heme oxygenase-1 gene promoter and its application in association studies with Alzheimer and Parkinson disease. Hum Genet 1997;100:145-147.
35. Abraham NG, Drummond GS, Lutton JD, Kappas A. The biological significance and physiological role of heme oxygenase. Cell Physiol Biochem 1996;6:129-168.
36. Balldin J, Gottfries C, Karlsson I, Lindstedt G, Langstrom G, Walinder J. Dexamethasone suppression test and serum prolactin in dementia disorders. Br J Psychiatr 1983:143-277-281.
37. Litvan I. Methodological and research issues in the evaluation of biological diagnostic markers for Alzheimer's disease. Neurobiol Aging 1998;19:121-123.
38. Liebson E, Albert ML. Cognitive changes in dementia of the Alzheimer type. In: Calne DB, ed. Neurodegenerative diseases. Philadelphia: WB Saunders, 1994:615-629.
39. Thal L. Potential prevention strategies for Alzheimer's disease. Alzheimer Dis Assoc Disord 1996;10(suppl 1):6-8.
40. Klunk WE. Biological markers of Alzheimer's disease. Neurobiol Aging 1998;19:145-147.