Review of periodic limb movement and restless leg syndrome

Journal of Postgraduate Medicine

Volumn 56, Issue 2, 2010, Pages 157-162

  Natarajan, R ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Periodic limb movement; PLM; restless leg syndrome; RLS

Indexed keywords

BENZODIAZEPINE RECEPTOR STIMULATING AGENT; CLONAZEPAM; DIPRENORPHINE C 11; DOMPERIDONE; GABAPENTIN; IRON; LAMOTRIGINE; LEVODOPA; OPIATE; PERGOLIDE; PRAMIPEXOLE; ROPINIROLE; TRAMADOL; UNCLASSIFIED DRUG; ZALEPLON; ZOLPIDEM;

ATTENTION DEFICIT DISORDER; AWARENESS; BEDTIME DOSAGE; CLINICAL PRACTICE; CLINICAL TRIAL; DIABETIC NEUROPATHY; DISEASE ASSOCIATION; DISEASE EXACERBATION; DISEASE TRANSMISSION; DIZZINESS; DOPAMINERGIC SYSTEM; FLUID RETENTION; GENETICS; HEART MUSCLE FIBROSIS; HUMAN; INSOMNIA; IRON DEFICIENCY; LIMB MOVEMENT; MEDIASTINUM DISEASE; MEDICAL SPECIALIST; MEDLINE; NAUSEA; NEUROPATHY; NIGRONEOSTRIATAL SYSTEM; NOSE CONGESTION; PATHOPHYSIOLOGY; PHYSICIAN; POLYSOMNOGRAPHY; PREVALENCE; RESTLESS LEGS SYNDROME; RETROPERITONEAL FIBROSIS; REVIEW; SIDE EFFECT; SLEEP APNEA SYNDROME; SLEEP DISORDER; SOMNOLENCE; UPPER AIRWAY RESISTANCE SYNDROME; UPPER RESPIRATORY TRACT;

DOPAMINE AGENTS; HUMANS; INDIA; NOCTURNAL MYOCLONUS SYNDROME; PREVALENCE; QUALITY OF LIFE; RESTLESS LEGS SYNDROME;

EID: 77954969396     PISSN: 00223859     EISSN: 09722823     Source Type: Journal    
DOI: 10.4103/0022-3859.65284     Document Type: Review

References (49)

1. Rijsman RM, de Weerd AW. Secondary periodic limb movement disorder and restless legs syndrome. Sleep Med Rev 1999;3:147-158
2. Stiasny K, Oertel WH, Trenkwalder C. Clinical symptomatology and treatment of restless legs syndrome and periodic limb movement disorder. Sleep Med Rev 2002;6:253-265
3. Recording and scoring leg movements. The Atlas Task Force. Sleep 1993;16:748-759
4. Exar EN, Collop NA. The association of upper airway resistance with periodic limb movements. Sleep 2001;24:188-192
5. Baran AS, Richert AC, Roffwarg HP. Periodic limb movements and nasal CPAP. Sleep 2000;23:A336.
6. Baran AS, Richert AC, Douglass AB, May W, Ansarin K. Change in periodic limb movement index during treatment of obstructive sleep apnea with continuous positive airway pressure. Sleep 2003;26:717-720
7. Norman RG, Ahmed MM, Walsleben JA, Rapoport DM. Detection of respiratory events during NPSG: Nasal cannula/pressure sensor versus thermistor. Sleep 1997;20:1175-1184
8. Allen RP, Picchietti D, Hening WA, Trenkwalder C, Walters AS, Montplaisi J, et al. Restless legs syndrome: Diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. Sleep Med 2003;4:101-119
9. Hening W, Walters AS, Allen RP, Montplaisir J, Myers A, Ferini-Strambi L. Impact, diagnosis and treatment of restless legs syndrome (RLS) in a primary care population: The REST (RLS epidemiology, symptoms, and treatment) primary care study. Sleep Med 2004;5:237-246
10. Tan EK, Seah A, See SJ, Lim E, Wong MC, Koh KK. Restless legs syndrome in an Asian population: A study in Singapore. Mov Disord 2001;16:577-579
11. Kim J, Choi C, Shin K, Yi H, Park M, Cho N, et al. Prevalence of restless legs syndrome and associated factors in the Korean adult population: The Korean Health and Genome Study. Psychiatry Clin Neurosci 2005;59:350-353
12. Rangarajan S, Rangarajan S, D'Souza GA. Restless legs syndrome in an Indian urban population. Sleep Med 2007;9:88-93.
13. Berger K, Luedemann J, Trenkwalder C, John U, Kessler C. Sex and the risk of restless legs syndrome in the general population. Arch Intern Med 2004;164:196-202.
14. Phillips B, Young T, Finn L, Asher K, Hening WA, Purvis C. Epidemiology of restless legs symptoms in adults. Arch Intern Med 2000;160:2137-2141
15. Lee HB, Hening WA, Allen RP, Earley CJ, Eaton WW, Lyketsos CG. Race and restless legs syndrome symptoms in an adult community sample in east Baltimore. Sleep Med 2006;7:642-645
16. Winkelman JW, Chertow GM, Lazarus JM. Restless legs syndrome in end-stage renal disease. Am J Kidney Dis 1996;28:372-378
17. Manconi M, Govoni V, De Vito A, Economou NT, Cesnik E, Mollica G, et al. Pregnancy as a risk factor for restless legs syndrome. Sleep Med 2004;5:305-308
18. Polo-Kantola P, Erkkola R. Sleep and the menopause. J Br Menopause Soc 2004;10:145-150
19. Högl B, Frauscher B, Seppi K, Ulmer H, Poewe W. Transient restless legs syndrome after spinal anesthesia: A prospective study. Neurology 2002;59:1705-1707
20. Skomro RP, Ludwig S, Salamon E, Kryger MH. Sleep complaints and restless legs syndrome in adult type 2 diabetics. Sleep Med 2001;2:417-422
21. Merlino G, Fratticci L, Valente M, Del Giudice A, Noacco C, Dolso P, et al. Association of restless legs syndrome in type 2 diabetes: A case-control study. Sleep 2007;30:866-871
22. Gómez-Esteban JC, Zarranz JJ, Tijero B, Velasco F, Barcena J, Rouco I, et al. Restless legs syndrome in Parkinson's disease. Mov Disord 2007;22:1912-1916
23. Rye DB, Adler CH, Allen RP, Becker P, Buchfuhrer MJ, Chokroverty S, et al. RLS Medical Bulletin. Rochester, Minnesota: Restless Legs Syndrome Foundation; 2005.
24. Brown LK, Dedrick DL, Doggett JW, Guido PS. Antidepressant medication use and restless legs syndrome in patients presenting with insomnia. Sleep Med 2005;6:443-450
25. Picchietti DL, England SJ, Walters AS, Willis K, Verrico T. Periodic limb movement disorder and restless legs syndrome in children with attention-deficit hyperactivity disorder. J Child Neurol 1998;13:588-594
26. Walters AS, Mandelbaum DE, Lewin DS, Kugler S, England SJ, Miller M. Dopaminergic therapy in children with restless legs/periodic limb movements in sleep and ADHD. Dopaminergic Therapy Study Group. Pediatr Neurol 2000;22:182-186
27. Aukerman MM, Aukerman D, Bayard M, Tudifer F, Thorp L, Bailey B. Exercise and restless legs syndrome: A randomized controlled trial. J Am Board Fam Med 2006;19:487-493
28. Esteves AM, de Mello MT, Pradella-Hallinan M, Tufik S. Effect of acute and chronic physical exercise on patients with periodic leg movements. Med Sci Sports Exerc 2009;41:237-242
29. Walters AS, Hickey K, Maltzman J, Verrico T, Joseph D, Hening W, et al. A questionnaire study of 138 patients with restless legs syndrome: the "Night-Walkers" survey. Neurology. 1996;46: 92-95 .
30. Dhawan V, Ali M, Chaudhuri KR. Genetic aspects of restless legs syndrome. Postgrad Med J 2006;82:626-629
31. Stefansson H, Rye DB, Hicks A, Petursson H, Ingason A, Thorgeirsson TE, et al. A genetic risk factor for periodic limb movements in sleep. N Engl J Med 2007;357:639-647
32. Winkelmann J, Muller-Myhsok B. Genetics of restless legs syndrome: A burning urge to move. Neurology 2008;70:664-665
33. Winkelmann J, Muller-Myhsok B, Wittchen HU, Hock B, Prager M, Pfister H, et al. Complex segregation analysis of restless legs syndrome provides evidence for an autosomal dominant mode of inheritance in early age at onset families. Ann Neurol 2002;52:297-302.
34. Ondo WG, He Y, Rajasekaran S, Le WD. Clinical correlates of 6-hydroxydopamine injections into A11 dopaminergic neurons in rats: A possible model for restless legs syndrome. Mov Disord 2000;15:154-158
35. Earley CJ, Connor JR, Beard JL, Malecki EA, Epstein DK, Allen RP. Abnormalities in CSF concentrations of ferritin and transferrin in restless legs syndrome. Neurology 2000;54:1698-1700
36. Earley CJ, B Barker P, Horska A, Allen RP. MRI-determined regional brain iron concentrations in early-and late-onset restless legs syndrome. Sleep Med 2006;7:458-461
37. Connor JR, Wang XS, Patton SM, Menzies SL, Troncoso JC, Earley CJ, et al. Decreased transferrin receptor expression by neuromelanin cells in restless legs syndrome. Neurology 2004;62:1563-1567
38. Earley CJ, Allen RP, Beard JL, Connor JR. Insight into the pathophysiology of restless legs syndrome. J Neurosci Res 2000;62:623-628
39. Paulus W, Dowling P, Rijsman R, Stiasy-Kolster K, Trenkwalder C and Weerd A. Pathophysiological concepts of restless legs syndrome, Mov Disord, 2007;22:1451 6
40. von Spiczak S, Whone AL, Hammers A, Asselin MC, Turkheimer F, Tings T, et al. The role of opioids in restless legs syndrome: An [11C]diprenorphine PET study. Brain 2005;128:906-917
41. Hening W, Allen R, Earley C, Kushida C, Picchietti D, Silber M. The treatment of restless leg syndrome and periodic limb movement disorder: An American Academy of Sleep Medicine Review. Sleep 1999;22:970-999
42. Hening WA, Allen RP, Earley CJ, Picchietti DL, Silber MH; Restless Legs Syndrome Task Force of the Standards of Practice Committee of the American Academy of Sleep Medicine. An update on the dopaminergic treatment of restless legs syndrome and periodic limb movement disorder. Sleep 2004;27:560-583
43. Agarwal P, Fahn S, Frucht SJ. Diagnosis and management of pergolide-induced fibrosis. Mov Disord 2004;19:699-704.
44. Allen RP, Earley CJ. Augmentation of the restless legs syndrome with carbidopa/levodopa. Sleep 1996;19:205-213
45. Walters AS, Winkelmann J, Trenkwalder C, Fry JM, Kataria V, Wagner M, et al. Long-term follow-up on restless legs syndrome patients treated with opioids. Mov Disord 2001;16:1105-1109 (Pubitemid 36041223)
46. Happe S, Klosch G, Saletu B, Zeitlhofer J. Treatment of idiopathic restless legs syndrome (RLS) with gabapentin. Neurology 2001;57:1717-1719
47. Garcia-Borreguero D, Larrosa O, de la Llave Y, Verger K, Masramon X, Hernandez G. Treatment of restless legs syndrome with gabapentin: A double-blind, cross-over study. Neurology 2002;59:1573-1579
48. Mellick GA, Mellick LB. Management of restless legs syndrome with gabapentin (Neurontin). Sleep 1996;19:224-226
49. Staedt J, Stoppe G, Riemann H, Hajak G, Ruther E, Riederer P. Lamotrigine in the treatment of nocturnal myoclonus syndrome (NMS): Two case reports. J Neural Transm 1996;103:355-361